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Journal of Agromedicine and Medical Sciences
Published by Universitas Jember
ISSN : 24609048     EISSN : 27145654     DOI : -
Core Subject : Health,
Jurnal Agromedicine and Medical Sciences (AMS) adalah jurnal berkala empat bulan (Februari, Juni dan Oktober) yang berisi berbagai artikel dalam bentuk penelitian, tinjauan sistematis dan laporan kasus dalam bidang kedokteran dengan fokus pada ilmu-ilmu kedokteran dasar, kedokteran klinis dan agromedis.
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Articles 305 Documents
Association between Physical Activity with Burnout Syndrome After the Second Wave of the COVID-19 Pandemic in Health Workers at RSD dr. Soebandi Jember Dilar Bambang Sudito; Ancah C N Marchianti; Adelia Handoko
Journal of Agromedicine and Medical Sciences Vol 10 No 2 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i2.30975

Abstract

Health workers have a key role in handling the COVID-19 pandemic. Working in a stressful environment can affect the emotional stability of health workers and can trigger burnout syndrome. Physical activity is one of the factors that can trigger burnout syndrome. Therefore, this study was conducted to analyze the relationship between physical activity and the incidence of burnout syndrome after the peak of the second wave of the COVID-19 pandemic among health workers at RSD dr. Soebandi Jember. This cross-sectional analytic observational study conducted from November to December 2021 was attended by 84 doctors and nurses working at RSD dr. Soebandi. The data were obtained using the Global Physical Activity Questionnaire and the Maslach Burnout Inventory. Ordinal logistic regression analysis showed a significant relationship between work activities and the level of burnout syndrome (p = 0.04). The effect of physical activity on burnout syndrome in this study was 32%. Our recommend is that further research is needed on the factors that can affect burnout syndrome with more objective research methods so that more valid results are obtained.
Effect of Andaliman Fruit Extract (Zanthoxylum acanthopodium DC.) on The Liver of Tartrazine Induced Rat (Rattus norvegicus L.) Juandi AlGani Sika; Husnarika Febriani; Syukriah Syukriah
Journal of Agromedicine and Medical Sciences Vol 10 No 1 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i1.39415

Abstract

Effect of tartrazine as synthetic food coloring that is consumed for long time has a toxic effect by free radicals in large quantities creating an imbalance in body and triggering disturbances, namely liver function. Free radicals can be minimized with antioxidants so they can reduce free radicals in body. Antioxidants can be found in all types of plants, one of which is Andaliman fruit. The purpose of this study was to determine effect ethanol extract of Andaliman fruit on SGOT-SGPT levels and histology of tartrazine-induced white rats. The research design used 25 white rats with 5 treatments and 5 replications for 30 days. Negative control group induced by 1% CMC, positive control induced by tartrazine 15 mg/kg BW, treatment groups 1, 2, 3 induced by tartrazine 15 mg/kg BW and ethanol extract andaliman fruit 150 mg/kg BW, 300 mg/kg BW, and 450 mg/kg BW. The stages in this study were screening for phytochemicals, total flavonoids and antioxidant activity as well as measurement of SGOT-SGPT levels and observation of liver histology. Data were analyzed using one way Anova and Duncan's further test. Results showed that phytochemical screening of Andaliman fruit extract contained flavonoids, terpenoids, steroids and tannins. Total flavonoid content in extract was 7.8163 mgQE/g extract. And level antioxidant activity in the extract has an IC50 value of 102.35 ppm. The results of this study also showed that the extract had an effect on decreasing levels of SGOT-SGPT and could minimize liver histological damage after being induced by tartrazine. Keywords: Andaliman, tartrazine, SGOT-SGPT, liver histology
Diet Reduce Apnea Hypopnea Index (Ahi) Score in Obstructive Sleep Apnea Patient: Systematic Review and Meta-analysis Adella Bintang Saputri; Nindya Shinta Rumastika; Muhammad Afiful Jauhani; Wiwien Sugih Utami; Jauhar Firdaus
Journal of Agromedicine and Medical Sciences Vol 10 No 2 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i2.38538

Abstract

Obstructive sleep apnea (OSA) is a breathing disorder during sleep that can cause obstruction to the flow of breathing with characteristics such as collapse of the upper airway which can cause breathing to stop, either completely (apnea) or partial (hypopnea). Based on a study of taxi drivers in Jakarta, it was found that 52,5% of the sample had OSA. One of the main factors for OSA is obesity. Based on The American Academy of Sleep Medicine (AASM) recommends weight loss through lifestyle modifications (eg applying diet) as a treatment option for AHI improvement in OSA. The purpose of writing this article is to prove that adopting a diet can reduce the apnea hypopnea index (AHI) of OSA. The method in this study is a systematic review and meta-analysis using secondary data derived from PubMed, Science Direct, and Springer databases published from 2019 to 2022.. A total of six randomized controlled trial (RCT) articles were investigated by meta-analysis The weighted mean difference in AHI (-6,77 event/d with 95% CI: -13,42 to -0,1) significantly favoured diet over control arms. Based on the results of a systematic review and meta-analysis of six articles, the application of a diet is proven to reduce AHI scores in OSA patients. Keywords: Obstructive sleep apnea, Apnea hypopnea index, Diet
Anti-lipase Activity of Kemuning (Murraya paniculata) Leaves Extract and Its Fractions Nuri Nuri; Tazkiyatul Fitriyah; Endah Puspitasari; Bawon Triatmoko; Dewi Dianasari
Journal of Agromedicine and Medical Sciences Vol 10 No 1 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i1.44240

Abstract

Kemuning (Murraya paniculata) belongs to the Rutaceae family, it grows a lot in tropical areas such as Indonesia. Traditionally, Kemuning leaves are used for weight loss preparations and are believed to contain compounds that can inhibit pancreatic lipase, including flavonoids. This study aimed to reveal the antilipase activity of Kemuning leaves extract and its fractions. The extraction of Kemuning leaves was carried out by maceration with 70% ethanol as solvent. The vacuum liquid chromatography method was used to separate the secondary metabolites in the extract with the stationary phase of silica gel and the eluent mixture of n-hexane, ethyl acetate, and methanol in a gradient manner. Meanwhile, the antilipase activity was tested by colorimetric method, with p-nitrophenyl butyrate as a substrate and orlistat as a positive control. The extract obtained was 19.94% of the weight of the simplicia. The separated extract was collected in 20 flasks and then combined based on the Rf value of the spots observed on thin layer chromatography (TLC) producing 8 fractions (fractions A-H). The percentage yields of fractions A-H were 1.20, 1.33, 1.80, 3.92, 3.57, 4.20, 16.85, and 14.47%, respectively. Antilipase activity was indicated by IC50 values, which were 17.603 ± 1.660 and 108.554 ± 1.660 µg/mL for orlistat and extract, respectively. The antilipase activities of fractions A-H were 130.19 ± 2.90, 119.52 ± 1.95, 96.95 ± 1.81, 91.65 ± 0.78, 95.30 ± 1.46, 114.76 ± 2.87, 127.07 ± 3.56, and 134,04 ± 3.16 µg/mL, respectively. Based on these results, it can be concluded that the extract and its fractions exhibit very strong antilipase activity. Keywords: Murraya paniculata; extract; fraction; antilipase
Ventricular Septal Defect And Maternal History Of Epilepsy: A Case Report Ngurah Agung Reza Satria Nugraha Putra; Nyoman Suciawan; Ida Bagus Komang Arjawa
Journal of Agromedicine and Medical Sciences Vol 10 No 1 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i1.44182

Abstract

Pregnancy with epilepsy can cause major risks for both the mother and the offspring. It is known that the use of antiepileptic drugs (AEDs) during pregnancy can increase the risk of cardiac malformations. This journal reports a 19-day-old male infant who came with complaints of shortness of breath and a blue lip 2 days before admission. The mother had a history of epilepsy and had regularly taken epilepsy medication since before pregnancy. Physical examination revealed cyanotic lips, chest wall retraction, coarse crackles, and murmurs. The patient's symptoms and signs were associated with congenital heart disease, so he was further observed in the NICU. After bedside echocardiography, the results showed a patent foramen ovale and perimembranous ventricular septal defect. The teratogenic effect of AED is thought to be one of the major causative factors of congenital heart disease. A ventricular septal defect is the most common cardiac malformation found in population-based studies. The long-term effects of AED exposure during pregnancy require further investigation, both in terms of the type of AED (old or new) and the duration of AED consumption. It is important to educate mothers-to-be about this, especially to avoid the risk of congenital heart disease in their offspring. Keywords: epilepsy, ventricular septal defect, cardiac malformation.
Successful Treatment of Severe Generalized Tetanus with Refractory Spasm and Pneumonia Co-Infection: a Case Report Komang Yunita Wiryaning Putri; Ichlasul Mahdi Fardhani; Muhammad Isra Rafidin Rayyan
Journal of Agromedicine and Medical Sciences Vol 10 No 2 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i2.47191

Abstract

Background: Tetanus is a high mortality rate infectious disease caused by Clostridium tetani. Although it can be prevented through vaccination, tetanus remains a significant problem, especially in developing countries, so comprehensive management is needed to prevent more fatal complications. Case report: A 52-year-old patient was diagnosed with tetanus due to exposure to tree thorns and experienced muscle spasms and jaw stiffness that could not be controlled with benzodiazepine agents alone. The patient was treated for more than 30 days in the intensive care unit with mechanical ventilation, immunoglobulin, antibiotics, antispasms, and sedatives. Patients experience autonomic dysfunction, causing bradycardia, tachycardia, and fluctuating blood pressure. In addition, the patient was also infected with Pseudomonas aeruginosa pneumonia during the treatment period. Finally, the patient was successfully treated and removed. Conclusion: This case report highlights the importance of multidisciplinary ICU care in diagnosis and therapy, which is expected to provide the best patient outcomes. Keywords: Generalized tetanus; refractory spasms; pneumonia; neuroinfectious disease
Cover Vol 10 No.3 2024 Febianti, Zahrah
Journal of Agromedicine and Medical Sciences Vol 10 No 3 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i3.53144

Abstract

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Reliability of Using the Scabies Detection Form (DESKAB) in Islamic Boarding Schools Prasasty, Gita Dwi; Anwar, Chairil; Hafy, Zen; Liberty, Iche Andriyani; Argentina, Fiva; Aryani, Inda Astri
Journal of Agromedicine and Medical Sciences Vol 10 No 3 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i3.44810

Abstract

Scabies is an infectious skin disease caused by the Sarcoptes scabiei. This mite infestations not only cause skin damage, but can develop into local, even systemic skin infections. Therefore, instruments are needed that help early detection of scabies, especially through diagnosis in communities such as Islamic boarding schools. This study aimed to analyze the reliability of the scabies detection form (DESKAB) between Madrasah Aliyah female student rater and dermatovenerologist rater. Based on the results of the examination and Cohen's kappa test, a coefficient of 0.84 was obtained, which means that the level of reliability of the DESKAB form is strong, and a p value of 0.019 means that there is agreement in the perception of the diagnosis of scabies by the two raters. The DESKAB form can be recommended as an early detection instrument for non-medical personnel before being confirmed by medical personnel Keywords: DESKAB; diagnosis; non-medic; scabies
Toxicity of Ceremai (Phyllanthus Acidus) and Zodia (Evodia Suaveolens) Leaf Extracts on Mortality of Aedes Aegypti Larvae Imtiyaz, Andi Hilman; Armiyanti, Yunita; Ulfa, Evi Umayah; Rohmah, Etik Ainun
Journal of Agromedicine and Medical Sciences Vol 10 No 3 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i3.48674

Abstract

Aedes aegypti is the vector that carries Dengue Hemorrhagic Fever (DHF). Various strategies have been implemented to control the spread of the Aedes aegypti, one of which is using temephos larvicide. The use of temephos causes Aedes aegypti resistance and environmental pollution. Therefore, it is necessary to develop a bio-larvicide using ceremai leaf (Phyllanthus acidus) and zodia leaf (Evodia suaveolens). This study aimed to determine the toxicity of ceremai leaf and zodia leaf extracts on the mortality of Aedes aegypti larvae. This type of research is a pure experiment using a Completely Randomized Design. The research sample was third instar Aedes aegypti larvae. There were 7 groups consisting of 1 negative control (aquadest and tween20), 1 positive control (temephos 0.008%) and 5 treatment groups (ceremai leaf extract and zodia leaf extract). Larval mortality data were observed after 24 hours of exposure. The results of the Kruskal Wallis test showed that there was a difference in mortality between groups with a value of p : 0.020 (p < 0.05). Zodia leaf extract at 0.2% has the highest toxicity to the mortality of Aedes aegypti larvae. The probit test results of zodia leaf extract showed LC50 and LC90 values of 0.075% and 0.121% within 24 hours of exposure. Zodia leaf ethanol extract has effectiveness as larvicide of Aedes aegypti. Keywords: Aedes aegypti, larvicide, extract, ceremai, zodia
Generalized Peritonitis due to Multiple Perforation and Necrotic of Ileum : a Case Report Rifqyan, Anizar; Tinelo, Ineza Fadia; Bellynda, Wynne; Islami, Ananda Aliza Nurul; Hertanto, Annisa Citra Herrastri
Journal of Agromedicine and Medical Sciences Vol 10 No 3 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i3.46889

Abstract

Peritonitis is a life-threatening condition with a mortality rate according to WHO of 5.9 million per year. We report the case of an elderly man who complained of severe pain in the entire abdominal region and the results of a plain abdominal radiograph showed peritonitis and obstructive ileus. Exploratory laparotomy and ileal resection were performed, and multiple ileal perforations, 120 cm of necrotic ileum and grade IV adhesions were found. There was post-surgical complications of sepsis and the patient died on the seventh post-operative day. Histopathological examination shows images that was not contributory to the diagnosis. There were no features of malignancy or tendency to a specific infection. Non-specific small bowel perforation can be considered as the etiology of peritonitis because there are no specific pathopneumonic characteristics. Diagnostic and management of surgical emergencies plays a very important role in patient prognosis. Keywords: generalized peritonitis;small bowel perforation;obstructive ileus.