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Global Medical and Health Communication
Published by Universitas Islam Bandung
ISSN : 23019123     EISSN : 24605441     DOI : https://doi.org/10.29313/gmhc
Core Subject : Health, Science,
Dentistry Health Professions Immunology & microbiology Nursing Public Health
Global Medical and Health Communication is a journal that publishes research articles on medical and health published every 4 (four) months (April, August, and December). Articles are original research that needs to be disseminated and written in English. Subjects suitable for publication include but are not limited to the following fields of anesthesiology and intensive care, biochemistry, biomolecular, cardiovascular, child health, dentistry, dermatology and venerology, endocrinology, environmental health, epidemiology, geriatric, hematology, histology, histopathology, immunology, internal medicine, nursing sciences, midwifery, nutrition, nutrition and metabolism, obstetrics and gynecology, occupational health, oncology, ophthalmology, oral biology, orthopedics and traumatology, otorhinolaryngology, pharmacology, pharmacy, preventive medicine, public health, pulmonology, radiology, and reproductive health.
Arjuna Subject : Kedokteran - Epidemilogi
Articles 12 Documents
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Search results for , issue "Vol 12, No 2 (2024)" : 12 Documents clear
Exploring the Association between Diabetes Mellitus, Obesity, and Recurrent Stroke Events: a Cross-sectional Study Marlina, Marlina; Sari, Maulida; Amni, Rahmalia
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13555

Abstract

Stroke is the most significant cause of death and cause of disability in the world because it causes neurological deficits in sufferers, such as muscle paralysis, swallowing weakness, communication damage, and vision disorders to cause death. Stroke can be recurrent and have a severe impact compared to the initial attack. The purpose of this study was to explore the association between diabetes mellitus, obesity, and the incidence of recurrent strokes in post-stroke patients at a regional general hospital in Aceh province. It is a cross-sectional study carried out from 3–12 August 2022. The sampling technique used in this study was a purposive sampling of 154 patients. The instruments used were questionnaires of patient demographic characteristics, data analysis using chi-square assays, and logistic regression. The results showed that there was no association between diabetes mellitus (p>0.05) and obesity (p>0.05) with the incidence of recurrent strokes. One of the preventive measures for the occurrence of recurrent strokes is to provide education about the prevention of recurrent strokes related to diabetes mellitus and obesity, one of which is a healthy lifestyle. In conclusion, there is no relationship between diabetes mellitus, obesity, and the incidence of recurrent strokes in post-stroke patients at a regional general hospital in Aceh province.
Evaluating Risk Factors for Early-onset Neonatal Sepsis Iskandar, Wedi; Juniartho, Rizky Dwi; Triyani, Yani; Permatagalih, Vidi
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13940

Abstract

Neonatal sepsis is a systemic infection that occurs in infants at 28 days of life and is a significant cause of morbidity and death in newborns. Early-onset neonatal sepsis (EONS) occurs within 72 hours after birth and is often associated with infections contracted before or during childbirth. The study aims to evaluate the risk factors of EONS. The study design was a case-control retrospective observational study that evaluated the medical records of neonates who were admitted to the neonatal care unit of Al Islam Hospital Bandung from January 2020 to December 2022. This study assessed the impact of independent variables such as gestational age, birth weight, premature rupture of membrane (PROM), miconeal amniotic fluid, APGAR score of 5 minutes, and the mother's white blood cell count elevation (>15,000/µl). The logistic regression analyses were employed to analyze the data. The logistic regression analyses were employed to analyze the data. The study included 3,103 neonates, of whom 124 met the inclusion criteria. Thirty-nine patients (31.35%) were diagnosed with sepsis, while 85 patients (68.55%) did not have sepsis. Based on bivariate analysis, EONS was significantly linked to low birth weight (p=0.027, 95% CI=0.184 to 0.902, OR=2.455), PROM (p=0.000, 95% CI=4.359 to 26.582, OR=10.764), and the mother's white blood cell count elevation (p=0.002, 95% CI=1.560 to 7.622, OR=3.448). On multivariate analysis, the risk factors were significantly associated (p<0.05), which had an influence of 38.4% on EONS (Nagelkerke R square=0.384). In conclusion, the risk factors for EONS were low birth weight, PROM, and elevation of white blood cell count in the mother, which increased by 38.4% with EONS.
Correlation of Subject Characteristics, Work Stress Levels, and Smoking Patterns among Educational Personnel at X University, Indonesia Makaginsar, Caecielia; Yuniarti, Yuniarti
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13842

Abstract

Human resources are among the crucial aspects of an organization, including in higher-education organizations. Educational personnel, a key component of the education system, are prone to work stress, which may trigger smoking behavior. Personal characteristics may also influence smoking behavior. This cross-sectional observational analytic study aimed to analyze the relationship between characteristics, work stress level, and smoking behavior of educational personnel of X University, Indonesia. On 30 April–Mei 2021, subjects were recruited through total sampling based on inclusion and exclusion criteria (n=100, all males). A questionnaire that had been tested for validity and reliability was used to collect data on subject characteristics and behaviors, while DASS-42 was used to measure work stress. Age, education level, length of work, and work stress were the independent variables, while smoking was the dependent variable. Data collected were analyzed univariately and bivariately using the chi-square test, with p<0.05 considered significant. Age, education, and length of work were found to be significantly correlated with smoking (p=0.007, 0.016, and 0.009, respectively). However, stress levels did not correlate with smoking (p=0.786). This suggests that age, education, and length of work significantly influence smoking behavior. It's crucial to interpret these findings with caution, especially considering that all subjects are males, who have been proven less prone to stress than females. This caution is necessary to ensure a comprehensive understanding of the factors influencing smoking behavior among educational personnel.
Self-medication for Cough: a Study of Smokers and Non-smokers in Surabaya Colleges Lorensia, Amelia; Suryadinata, Rivan Virlando; Hayati, Siti Nur; Suud, Suud
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.12367

Abstract

The number of smokers among students is increasing. Smoking can cause coughing, the body's defense mechanism for clearing the airways. Cough can be treated with self-medication, which can cause drug-related problems. The level of knowledge and perception can influence the choice of cough medicine used. The purpose of this study was to determine the knowledge and perceptions of cough medicine self-medication in smokers and non-smokers. This research method was a case-control study using a questionnaire of knowledge (definition, method of use, and indications) and perceptions (definition, side effects, and experience) regarding using self-medicated cough medicine. The research sample was adult students at a private university in Surabaya from January 2023 to April 2023, and it was collected using a purposive sampling method. The sample size was 124 respondents, 62 smoking and 62 non-smoking students. The level of knowledge in both groups was high, namely 51.62% in the smoker group and 58.84% in the non-smoker group. Meanwhile, the perception level in the smokers group was mostly bad (56.45%), in contrast to the non-smokers who had a good level of perception (64.52%). There was a significant difference in the level of knowledge (0.00) and perception (0.00) between smokers and non-smokers regarding cough medicine self-medication. Therefore, smokers have the same high level of expertise but lower levels of perception than non-smokers. Health promotion programs to increase knowledge are essential considerations in optimizing self-medication.
Effectiveness of Red Ginger (Zingiber officinale var. Rubrum) Foot Hydrotherapy in Lowering Blood Pressure among Pregnant Women with Hypertension Soviyati, Evi; Utari, Toto Sutarto Gani; Fazrin, Risa Mustika
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13993

Abstract

Pregnancy hypertension is one of the complications of pregnancy. One nonpharmacological treatment to reduce hypertension is the foot hydrotherapy method with red ginger (Zingiber officinale var. rubrum). The essential oil content of red ginger provides a warm effect and spicy aroma so that blood vessels widen and blood flow becomes smooth. The research aims to determine the effectiveness of red ginger foot hydrotherapy in lowering blood pressure among pregnant women with hypertension. This one-group pretest-posttest pre-experimental study design was conducted at the Talaga Community Health Centre, West Java, from May 2023 to July 2023. The sample was 32 pregnant women with hypertension. Bivariate analysis test using paired t-test. The average systolic blood pressure measurement results for pregnant women before the intervention were 154.09 mmHg, and after the intervention was given 140.22 mmHg, there was a decrease of 13.87 mmHg. The average diastole for pregnant women before the intervention was 100.22; after the intervention, it was 91.62, resulting in a reduction of around 8.6 mmHg. The paired t-test with a p-value <0.001 shows the effectiveness of foot hydrotherapy with red ginger in reducing blood pressure in pregnant women with hypertension. Red ginger using the foot hydrotherapy method has been proven effective in lowering blood pressure in pregnant women. To reduce the risk factors for pregnancy with hypertension, pharmacological and nonpharmacological therapy is a solution that needs to be considered. This research can become a reference for evidence-based midwifery practice in providing midwifery care.
Cardiac Histopathology Alterations Induced by Subchronic Mangosteen Rind Extract in Wistar Rats Ratwita, Welly; Nurrokhmawati, Yanti; Maheswari, Endah Nabilah
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13445

Abstract

Mangosteen (Garcinia mangostana L.) is renowned for its potent antioxidant characteristics, including free radical scavenging, and its antibacterial, antifungal, anti-inflammatory, and antidiabetic properties. This study aims to assess the subchronic toxicity effects of ethanol extract from mangosteen rind on the cardiac histopathology of male and female Wistar rats. This research was a posttest-only control group design. Forty biological specimens from 40 Wistar rats were divided into four groups, a control group, and three treatment groups, which were given ethanol extract of mangosteen rind with doses of 250 mg/kg, 500 mg/kg, and 1,000 mg/kg for 28 days. Cardiac specimens were prepared and examined using hematoxylin-eosin (HE) staining at the Anatomical Pathology Laboratory of Universitas Jenderal Achmad Yani in December 2021. The findings indicated that prolonged ingestion of large amounts of ethanol extract from mangosteen rind can cause toxic effects characterized by an inflammatory response in cardiac tissue. No fibrosis or hypertrophy was detected; however, inflammatory changes such as the presence of inflammatory cells, vacuolar changes, and neovascularization were observed. The inflammation observed might be due to excessive antioxidant administration leading to oxidative stress. Inflammatory cells may trigger fibrotic remodeling in the heart. The difference in the quantity of inflammatory cells between male and female rats suggests that gender influences the inflammatory response. Overall, administration of ethanol extract from mangosteen rind at doses of 250 mg/kg, 500 mg/kg, and 1,000 mg/kg cause subchronic toxicity effects on the heart histopathology of Wistar rats, marked by inflammation.
Effectiveness of Kegel Exercises on Perineal Wound Healing among Postpartum Women Rosyida, Desta Ayu Cahya; Hidyatunnikmah, Nina
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13736

Abstract

Perineal wound refers to a laceration or wound that occurs along the birth canal (perineum) due to the delivery process. Wound healing is a method involved in replacing and repairing damaged tissue's capacity. This study aims to determine the effectiveness of Kegel exercises on perineal wound healing. It was a quasi-experimental study with one group pretest-posttest design conducted in March–May 2023. Forty-five women with perineal wounds at the Arosbaya Public Health Center, a reputable healthcare facility in Bangkalan, East Java province, Indonesia known for its comprehensive postpartum care, were selected as the study samples through a random sampling technique. The pre-test was done by observing the perineal wound before doing Kegel exercises. At the intervention stage, respondents did Kegel exercises daily for seven days. The post-test was carried out on day 7, and then observation of the perineum wound was carried out. Data were collected using an observation sheet. T-test was applied for the statistical tests. The study results show that after carrying out Kegel exercises, the majority of the 45 respondents experienced changes; namely, 25 people experienced good wound healing, and the remaining 20 experienced poor wound healing. The calculated t value was higher than the t table value (−16.523>−2.015) and had a significance value of <0.05 (0.000<0.05). This study's findings have practical implications for postpartum care, as they highlight the potential of Kegel exercises in promoting perineal wound healing, thereby enhancing the knowledge and practice of healthcare professionals and postpartum women.
Stakeholder Insights on Malaria Elimination Strategies in Pangandaran, West Java: a Qualitative Analysis Faridah, Lia; Fauziah, Nisa; Adams, Fayyaza Faiz; Mufida, Hasna; Akbar, Muhamad Lazuardi; Salsabila, Pricillia Laurenza; Rufinus, Wilbert Bernardi; Virajati, Abimanyu Athallah; Angga, Anggisti Nurdinda Chaerany Putri; Mahira, Khansa; Zahra, Ridha Beta
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13483

Abstract

Indonesia has launched a determined effort to eliminate malaria by 2023, focusing on Java and Bali. Despite these efforts, Pangandaran in Java still faces malaria cases. This study aims to meticulously delve into the intricacies of the malaria elimination program's implementation while conducting a comprehensive evaluation of its effectiveness. Structured interviews were conducted with key stakeholders responsible for the malaria program in Pangandaran to extract invaluable insights. The study, carried out in November 2022, followed qualitative research with narrative analysis to reveal nuanced narratives from the participants. Findings from this rigorous analysis revealed a harmonious alignment between the malaria control program in Pangandaran and the Indonesian Ministry of Health guidelines. The strategy to combat malaria vectors in Pangandaran included mosquito net distribution, strategic larvicide application, and educational campaigns like Malaria Awareness Society (MASAMA). The expectation is that the current effective control program will resonate within the Pangandaran community, ultimately leading to the realization of the 2023 elimination target.
Impact of Propolis Administration on Osteocrin Expression and Osteoblast-to-Osteoclast Ratio in the Femurs of Rats Fed a High-fat Diet Widiyanti, Alvira; Tarawan, Vita Murniati; Lubis, Leonardo
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13833

Abstract

A high-fat diet (HFD) is associated with bone inflammatory processes that can affect bone remodeling balance. Osteocrin produced by periosteal osteoblasts correlates with osteoblast activity, is expressed on osteoblast-derived cells, and is localized in osteoblasts and young osteocytes. Propolis is an antioxidant and anti-inflammatory in bone remodeling by inhibiting proinflammatory factors NF-κB and COX-2, reducing inflammatory suppression of cytokines responsible for osteoclast differentiation and osteoblast apoptosis. The flavonoid content increases the production of nitric oxide and osteoprotegerin, which enhances osteoblastogenesis. This study determined the effect of propolis administration on bone formation and resorption in bone previously damaged by an HFD. This research was conducted in the Animal Laboratory of Postgraduate Building Dipati Ukur and Genetics and Molecular Laboratory Eycman Building, Faculty of Medicine, Universitas Padjadjaran. The research time was from January 2023–May 2024. Male Wistar rats were divided into four groups: normal chow diet (NCD), NCD with propolis administration, HFD, and HFD with propolis administration. The 12-week-old rats were given an HFD for 12 weeks and then treated with propolis at a 300 mg/kgBW dose for nine weeks. The administration of propolis increased the ratio of osteoblasts-osteoclast cells in the femur of the HFD rats but did not affect periosteal osteocrin expression.
Anti-hyperuricemia Potential of Ethyl Acetate Fraction from Ethanolic Stem Extract of Arcangelisia flava Fatmawati, Fatmawati; Saleh, Irsan; Parisa, Nita; Salni, Salni; Izzah, Puspita Nurul; Subandrate, Subandrate; Athiah, Medina
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13510

Abstract

Arcangelisia flava, with its secondary metabolites in flavonoids, has shown promising potential as an alternative treatment for hyperuricemia. The study aimed to determine the effectiveness of the ethyl acetate fraction from the ethanolic stem extract of Arcangelisia flava in inhibiting xanthine oxidase. This research, conducted at the Medical Basic Chemistry Laboratory Universitas Sriwijaya in September–December 2022, used in vitro study methods. The stem of Arcangelisia flava was extracted by maceration using ethanol. The ethanolic stem extract of Arcangelisia flava was then fractionated using n-hexane and ethyl acetate. The ethyl acetate fraction and ethanolic extract of Arcangelisia flava were measured to inhibit the xanthine oxidase using UV-vis spectrophotometry with allopurinol as a comparison. The IC50 was calculated by linear regression. The ethanol extract and ethyl acetate fraction have flavonoids, alkaloids, terpenoids, and quinones. The IC50 value of the ethanol extract was 30.04 ppm, the ethyl acetate fraction was 23.99 ppm, and the allopurinol was 17.16 ppm. The ethyl acetate fraction inhibited xanthine oxidase better than the ethanol extract. The study's significant finding is that the ethyl acetate fraction of the ethanolic stem extract of Arcangelisia flava strongly inhibits xanthine oxidase, offering a potential new avenue for treating hyperuricemia.

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