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Angka Kejadian dan Karakteristik Klinis Pasien Infeksi Jamur Invasif di RSUP Dr. Hasan Sadikin Tahun 2020 – 2022 Alessandro, Ariella; Fauziah, Nisa; Megantara, Imam; Wisaksana, Rudi; Dewi, Intan Mauli Warma
Jurnal Penyakit Dalam Indonesia Vol. 10, No. 4
Publisher : UI Scholars Hub

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Introduction. Invasive fungal infection (IFI) is increasingly common in patients at risk, especially those with impaired immune response. In Indonesia, there is currently a low prevalence of IFI which may be influenced by challenges in diagnosis. This study aimed to determine the prevalence and clinical characteristics of IFI patients in Dr. Hasan Sadikin Hospital in Bandung, Indonesia. Methods. This cross-sectional study was conducted at Dr. Hasan Sadikin Hospital. Data were collected using medical records of IFI patients diagnosed between 2020 and 2022 which were selected using total sampling method. Demographic data, clinical symptoms, radiological appearance, and laboratory results were recorded. Results. The prevalence of IFI in Dr. Hasan Sadikin Hospital between 2020 and 2022 was 0,04% (40 per 100,000 patients). The most common cause of invasive fungal infection was Cryptococcus spp. and Candida spp. Fever and loss of consciousness were the two most common signs and symptoms found in this study. HIV/AIDS was present in 51,4% of cases. The diagnostic test was mostly done with cryptococcal antigen (CrAg) examination. Lung involvement was common, appearing as consolidation, infiltration, and ground glass opacity in the lungs. The mortality rate of IFI patients was 51,4%. Conclusions. The prevalence of IFI in Dr. Hasan Sadikin Hospital was quite low, with HIV/AIDS as the most common risk factor. However, there was a high mortality rate found this study is high. Thus, timely diagnosis and antifungal treatment induction should be considered to improve the outcome of invasive fungal infection patients.

Diagnostic Value of Coproantigen for Detection of Giardia Infection in Stunted Children Octoviani, Fanny Anggraeni; Kurniawan, Agnes; Sari, Ika Puspa; Fauziah, Nisa; Faridah, Lia; Adrizain, Riyadi
Althea Medical Journal Vol 10, No 3 (2023)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v10n3.2860

Background: Giardiasis is a protozoa infection caused by Giardia intestinalis, which commonly infects children, impairing children’s growth, development, and cognitive function. Standard diagnosis is carried out by microscopic examination of stool. This study aimed to evaluate coproantigen examination in stunted children compared to microscopic examination.Methods: A cross-sectional study was performed on stools collected from a survey among stunted children in Bandung in 2019. Stools were preserved in 10% formaldehyde and kept at -20oC until used. Direct microscopy examination with 2% lugol solution and coproantigen ELISA test using Giardia Cryptosporidium (combo test) coproantigen test kit were performed in Parasitology Laboratory Faculty of Medicine, Universitas Indonesia.Result: A total of 99 stools originated from stunted children aged 2-6 years. with boys predominant (52.5%). Microscopic examination showed that 12.1% (12/99) of the children were harboring intestinal parasites, such as the protozoa Giardia intestinalis, Blastocystis spp, and Entamoeba coli (E. coli). Giardia was the primary infection (9.1%), of which single Giardia infection (n = 8) and mixed infection of Giardia and Blastocystis spp (n = 1). Interestingly, coproantigen examination resulted in 6 positive samples, and 4 samples agreed with the microscopy result. With a sensitivity of 44.4% and a specificity of 97.7%. The positive and negative predictive values were 66.7% and 94.7%, respectively.Conclusion: A moderate prevalence of Giardia in stunted children in Bandung regency has been observed. The combo coproantigen test method has high specificity and is suitable for use as a confirmation test to exclude Giardia infection.

Effectiveness of Various Mosquito Attractant Solutions to Control Mosquito Population Faridah, Lia; Albert, Christian; Fauziah, Nisa
Global Medical & Health Communication (GMHC) Vol 7, No 1 (2019)
Publisher : Universitas Islam Bandung

The vector-borne disease is a disease caused by an organism that can transmit disease between human or animal to human. In Indonesia, several vector-borne diseases are a burden of the government including dengue fever, chikungunya, filariasis, and malaria. The attractive baited lethal ovitrap (ALOT) is a novel strategy to alleviate mosquito populations in three main actions: attraction, an adulticide, and larvacide. Research using plant infusion can attract mosquitoes to lay their eggs is needed. This study aims to compare the effectiveness of the mosquito repellent solution using materials from organic waste in Bandung. This study was a quantitative analytic study with a quasi-experimental design conducted in the Faculty of Medicine Universitas Padjadjaran area in October 2016–July 2017. Research subjects are mosquito eggs in a solution which placed at 25 different places for every solution. The analysis was performed using Kruskal-Wallis test followed by the Dunn test. The result of the Kruskal-Wallis test indicates the difference of effectiveness of each solution (p<0.05). Based on the results of the Dunn test, the most significant difference found in the solution of wood shavings with the vegetable waste solution and the solution of wood shavings with corn straw (p<0.05). In conclusion, there is a difference in the effectiveness of the mosquito repellent solutions and the most attractive solution for mosquitoes to oviposit is the corn straw solution. EFEKTIVITAS BERBAGAI LARUTAN PENARIK NYAMUK UNTUK MENGONTROL POPULASI NYAMUKPenyakit tular vektor adalah penyakit yang disebabkan oleh organisme yang dapat mentransmisikan penyakit antarmanusia atau hewan ke manusia. Di Indonesia, terdapat beberapa penyakit tular vektor yang masih menjadi beban pemerintah, di antaranya demam berdarah, chikungunya, penyakit kaki gajah, dan malaria. Attractive baited lethal ovitrap (ALOT) merupakan strategi baru untuk menurunkan populasi nyamuk dalam tiga aksi utama, yaitu attraction, adulticide, dan larvacide. Penelitian terkait larutan dari tanaman yang dapat menarik nyamuk sangat diperlukan. Penelitian ini bertujuan membandingkan efektivitas larutan penarik nyamuk dengan menggunakan bahan dari limbah organik yang ada di Kota Bandung. Penelitian ini adalah penelitian analitik kuantitatif dengan desain quasi-eksperimental yang dilakukan di lingkungan Fakultas Kedokteran Universitas Padjadjaran pada bulan Oktober 2016–Juli 2017. Subjek penelitian merupakan telur nyamuk yang ada pada larutan yang diletakkan pada 25 titik untuk setiap larutan. Analisis dengan Uji Kruskal-Wallis yang dilanjutkan dengan Uji Dunn. Hasil penelitian dengan Uji Kruskal-Wallis menunjukkan perbedaan efektivitas tiap-tiap larutan (p<0,05). Berdasar atas hasil Uji Dunn, perbedaan yang paling signifikan terdapat pada larutan serutan kayu dengan larutan sampah sayur dan larutan serutan kayu dengan jerami jagung (p<0,05). Simpulan, terdapat perbedaan efektivitas larutan penarik nyamuk dan larutan yang menarik nyamuk paling banyak untuk bertelur adalah larutan jerami jagung.

Arbovirus Detection of Adult Female Aedes aegypti for Dengue Surveillance: a Cohort Study in Bandung City, Indonesia Faridah, Lia; Ekawardhani, Savira; Fauziah, Nisa; Djati, Imam Damar; Putra, Ramadhani Eka; Watanabe, Kozo
Global Medical & Health Communication (GMHC) Vol 11, No 3 (2023)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v11i3.12749

Dengue surveillance is an important activity to prevent dengue outbreaks. This activity becomes a significant challenge for the region with limited logistic capabilities. Developing a simple mathematical model to predict the possibility of dengue incidence provides a reliable early warning system. This study compared the correlation between vector (adult female Aedes aegypti) and arbovirus detection on a vector to dengue incidence, which generalized linear mixed models tested. The incidence of adult female Aedes aegypti and dengue fever cases were interpolated through third-power inverse distance weighting (IDW). A spatial correlation between female Aedes aegypti incidence and dengue incidence was obtained from polynomial regression. Collection sites were 16 villages in Bandung city, one of the significant dengue endemic areas in January–December 2017. A total of 8,402 mosquitoes of Aedes aegypti, Aedes albopictus, and Culex sp., with 17% belonging to Aedes aegypti as the subject of the dengue virus (DENV) infection test. Data analysis only showed a weak correlation between the numbers of adult female Aedes aegypti and dengue incidence. On the other hand, there is no correlation between positive dengue infection of vector and dengue incidence. This study highlights the importance of constant arbovirus surveillance and integrated surveillance methods on all possible dengue vectors to develop an early warning system for dengue incidence.

Stakeholder Insights on Malaria Elimination Strategies in Pangandaran, West Java: a Qualitative Analysis Faridah, Lia; Fauziah, Nisa; Adams, Fayyaza Faiz; Mufida, Hasna; Akbar, Muhamad Lazuardi; Salsabila, Pricillia Laurenza; Rufinus, Wilbert Bernardi; Virajati, Abimanyu Athallah; Angga, Anggisti Nurdinda Chaerany Putri; Mahira, Khansa; Zahra, Ridha Beta
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13483

Indonesia has launched a determined effort to eliminate malaria by 2023, focusing on Java and Bali. Despite these efforts, Pangandaran in Java still faces malaria cases. This study aims to meticulously delve into the intricacies of the malaria elimination program's implementation while conducting a comprehensive evaluation of its effectiveness. Structured interviews were conducted with key stakeholders responsible for the malaria program in Pangandaran to extract invaluable insights. The study, carried out in November 2022, followed qualitative research with narrative analysis to reveal nuanced narratives from the participants. Findings from this rigorous analysis revealed a harmonious alignment between the malaria control program in Pangandaran and the Indonesian Ministry of Health guidelines. The strategy to combat malaria vectors in Pangandaran included mosquito net distribution, strategic larvicide application, and educational campaigns like Malaria Awareness Society (MASAMA). The expectation is that the current effective control program will resonate within the Pangandaran community, ultimately leading to the realization of the 2023 elimination target.

Infeksi Oportunistik pada Pasien HIV yang Dirawat Inap di RSUP Dr. Hasan Sadikin Bandung Tahun 2019-2022 Salma, Katarina; Hartantri, Yovita; Fauziah, Nisa
Jurnal Penyakit Dalam Indonesia
Publisher : UI Scholars Hub

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Introduction. Human Immunodeficiency Virus (HIV) is a virus that infects and attacks the human immune system. The high morbidity and mortality rates in HIV patients can be attributed to various factors, one of which is the presence of opportunistic infections due to the weakened immune response, making HIV patients highly susceptible to other infections. This study aims to provide an overview of opportunistic infections in HIV patients hospitalized at Dr. Hasan Sadikin General Hospital in Bandung within the period of 2019-2022. Methods. This descriptive observational study was conducted on 255 HIV patients with opportunistic infections who were hospitalized at dr. Hasan Sadikin Hospital (RSHS), Bandung. The study utilized secondary data from medical records from 2019 to 2022. The sampling method employed in this research was total sampling. Data processing and analysis of the relationship between two variables, namely the number of opportunistic infections and length of hospital stay, with HIV stage, were performed using IBM SPSS Statistics software version 26. The statistical methods used in this analysis included the Chi-square test and the Mann-Whitney test. Results. The research findings indicated that the most common opportunistic infection in HIV patients was oral candidiasis (60,0%), followed by pulmonary tuberculosis (453,1%) and toxoplasmosis (45,136,5%). The prevalence of opportunistic infections was higher in males (79,2%) compared to females. The age group most affected was patients aged 24-44 years. There was also a significant association between the HIV stage and the number of opportunistic infections, with a higher number of opportunistic infections occurring in patients with stage 4 HIV. Conclusions. Oral candidiasis and tuberculosis are opportunistic infections with the highest prevalence among HIV patients who were hospitalized at dr. Hasan Sadikin Hospital during the period of 2019-2022.

Prevalence, Lesion Characteristics, Risk Factors of Scabies Transmission in Cats (Felis catus) at Go Pet Care Animal Clinic (2020-2022) Dara, Sarah Azzahra Dwi; Fauziah, Nisa; Khairani, Shafia
Journal of Parasite Science Vol. 9 No. 1 (2025): Journal of Parasite Science
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jops.v9i1.61622

The COVID-19 pandemic (2019-2021) resulted in a surge in pet adoptions, potentially elevating the risk of various diseases in domestic cats, including scabies. Scabies, a highly contagious dermatological condition, is primarily caused by parasitic mites such as Notoedres cati and Sarcoptes scabiei. This study aimed to investigate the prevalence, clinical manifestations, and associated risk factors of scabies in domestic cats at Go Pet Care Animal Clinic in West Bandung Regency over the period from 2020 to 2022. Utilizing a cross-sectional study design, secondary data were extracted from medical records and analyzed using Microsoft Excel and SPSS version 29.0.1.0. A chi-square test was performed with a 95% confidence level (α = 0.05) to assess the statistical significance of the findings. Out of 71 cats diagnosed with scabies, the highest incidence was observed in cats under one year of age (kittens), long-haired breeds, and females. The prevalence of scabies showed a significant increase, rising from 2% to 11.2% over the study period. Common clinical manifestations included alopecia and crusting. Statistical analysis revealed that age was a significant risk factor influencing the prevalence of scabies. These findings underscore the need for heightened awareness and preventive measures for scabies, particularly in younger and long-haired cats.

Community Participation and Mosquito Breeding Sites in Cimahi City: Current Conditions and Challenges in Dengue Fever Control Faridah, Lia; Angga, Anggisti Nurdinda Chaerany Putri; Fauziah, Nisa; Jaya, I Gede Nyoman Mindra
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.14241

In 2021, Cimahi City recorded the 5th highest dengue fever (DF) cases among 27 districts/cities in West Java. Efforts to control DF have been going on for several decades, with one strategy being to involve community participation in eliminating mosquito breeding sites. This research evaluated community participation in Cimahi city by identifying mosquito breeding locations inside and outside the home. Samples were taken from 15 sub-districts in Cimahi city. The research population involved houses in 15 sub-districts, with a total sample of 1,560 houses representing each sub-district. Larval sampling was carried out in various water reservoirs, both natural and artificial, around residential areas. The successfully taken larvae were then identified and counted in the laboratory. The research showed that the most dominant mosquito breeding place was in bucket-type containers, namely 130 units (3.2%). Entomological data produced a free larva index (FLI) of 79.23%, a house index (HI) of 20.7%, a container index (CI) of 8.07%, and a Breteau index (BI) of 20.5%. This finding indicated a lack of community involvement in preventing vector-borne diseases by eliminating breeding sites. Cimahi city still had the potential to spread vector-borne diseases.

PREVALENCE AND CHARACTERISTICS OF PITYRIASIS VERSICOLOR RSUP DR. HASAN SADIKIN BANDUNG, PERIOD 2018–2022 Dinantha, Ahmad Zaky; Hidayah, Risa Miliawati Nurul; Fauziah, Nisa; ., Chrysanti; Pangastuti, Miranti
Media Dermato-Venereologica Indonesiana Vol 52 No 3 (2025): Media Dermato Venereologica Indonesiana
Publisher : Perhimpunan Dokter Spesialis Kulit dan Kelamin Indonesia (PERDOSKI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33820/mdvi.v52i3.480

Pendahuluan: Pitiriasis versikolor (PV) merupakan infeksi jamur superfisial yang disebabkan Malassezia spp. yang mengakibatkan perubahan warna kulit, sehingga menurunkan kualitas hidup pasien. Prevalensi PV di Indonesia masih belum pasti. Tujuan penelitian ini untuk mengetahui prevalensi dan karakteristik PV di salah satu rumah sakit rujukan tersier Jawa Barat. Metode: Penelitian ini dilakukan dengan metode deskriptif observasional retrospektif. Data berupa rekam medis pasien PV rawat jalan dan rawat inap di RSUP Dr. Hasan Sadikin, Bandung, periode 2018–2022. Hasil: Pada penelitian ini, didapatkan 47 pasien PV dari 386 pasien dermatomikosis. Pasien PV terbanyak pada kelompok usia 19–44 tahun, yaitu sebanyak 23 (48,9%); terdiri dari laki-laki 31 (66%) dan perempuan 16 (34%) orang. Lesi hipopigmentasi merupakan gejala terbanyak yang ditemukan pada 20 (42,3%) pasien. Badan dan ekstremitas merupakan lokasi terbanyak ditemukannya lesi, yaitu pada 12 (25,5%) pasien. Komorbid ditemukan pada 35 (74,5%) pasien. Tercatat 30 (63,8%) pasien tidak kontrol setelah pemeriksaan dan pemberian obat, serta ditemukan data yang tidak lengkap pada rekam medis. Kesimpulan: Kasus PV masih dapat ditemukan di fasilitas kesehatan tersier, kemungkinan karena terdiagnosis saat melakukan pemeriksaan untuk penyakit lainnya. Mayoritas pasien tidak kembali kontrol karena penyakit ini bersifat asimtomatis dan tidak dirasakan mengganggu

Community Participation and Mosquito Breeding Sites in Cimahi City: Current Conditions and Challenges in Dengue Fever Control Faridah, Lia; Angga, Anggisti Nurdinda Chaerany Putri; Fauziah, Nisa; Jaya, I Gede Nyoman Mindra
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.14138

In 2021, Cimahi City recorded the 5th highest dengue fever (DF) cases among 27 districts/cities in West Java. Efforts to control DF have been going on for several decades, with one strategy being to involve community participation in eliminating mosquito breeding sites. This research evaluated community participation in Cimahi city by identifying mosquito breeding locations inside and outside the home. Samples were taken from 15 sub-districts in Cimahi city. The research population involved houses in 15 sub-districts, with a total sample of 1,560 houses representing each sub-district. Larval sampling was carried out in various water reservoirs, both natural and artificial, around residential areas. The successfully taken larvae were then identified and counted in the laboratory. The research showed that the most dominant mosquito breeding place was in bucket-type containers, namely 130 units (3.2%). Entomological data produced a free larva index (FLI) of 79.23%, a house index (HI) of 20.7%, a container index (CI) of 8.07%, and a Breteau index (BI) of 20.5%. This finding indicated a lack of community involvement in preventing vector-borne diseases by eliminating breeding sites. Cimahi city still had the potential to spread vector-borne diseases.

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