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ISSN : 23015977     EISSN : 25277154     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
The Unram Medical Journal managed by the Medical Faculty of Mataram University is a scientific journal to publish the results of the latest research in the field of medical and health related. This journal promote medical sciences generated from basic sciences, clinical, and community research to integrate researches in all aspects of human health. This journal publishes original articles, reviews, and also case reports.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 408 Documents
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Peran Akupunktur sebagai Terapi Penunjang untuk Fibrilasi Atrium Ayu Permata Sari
Unram Medical Journal Vol 11 No 4 (2022): volume 11 no 4
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i4.795

Abstract

Atrium fibrillation (AF) is a common tachyarrhythmia and its prevalence increases with age. AF causes increased morbidity and mortality, including stroke, heart failure and decreased quality of life. The current treatment for AF has pro-arrhythmic side effects, procedurally expensive and complex, invasive procedures have a low success rate, high costs and long-term consumption of antiarrhythmic drugs can damage other organs outside the heart. Acupuncture is a method that is widely studied for cardiac arrhythmia problems, such as atrium fibrillation. Acupuncture works by stimulating autonomic nerves, decreasing sympathetic and vagal activity, thereby decreasing AF induction in the heart. Furthermore, acupuncture therapy compared with the anti-arrhythmic drug amiodarone was not more beneficial in the long term, but with acupuncture there were fewer side effects. Recent studies have also tried auricular acupuncture which is a branch of the vagal nerve and as the result the heart rhythm changes immediately to sinus rhythm, without cardioversion, either pharmacological or electrical. Therefore, acupuncture deserves to be considered as an alternative therapy option for patients with atrium fibrillation. Keywords : acupuncture, atrium fibrillation, cardiac arrhythmia, cardioversion
HUBUNGAN ANTARA GAMBARAN SITOLOGI MENGGUNAKAN METODE FNAB DENGAN RESPONS TERAPI PADA PASIEN LIMFADENITIS TUBERKULOSIS DI PULAU LOMBOK Tri Riskinie Istiharoh; Fathul Djannah; Indana Eva Ajmala
Unram Medical Journal Vol 11 No 4 (2022): volume 11 no 4
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i4.797

Abstract

ABSTRAK Latar Belakang: Tuberkulosis merupakan salah satu penyakit global dengan tingkat mortalitas dan morbiditas yang tinggi, dan paling banyak dijumpai pada wilayah Asia Tenggara. Indonesia menjadi negara dengan peringkat ketiga dengan kasus Tuberkulosis terbanyak di dunia. Limfadenitis Tuberkulosis adalah salah satu bentuk tersering dari infeksi Tuberkulosis ekstraparu. Salah satu gejala tersering yang ditemukan adalah pembesaran ukuran nodul kelenjar limfa dan penurunan berat badan. Metode: Penelitian ini merupakan penelitian studi analitik prospektif dengan teknik pengambilan sampel berupa purposive sampling, dengan jumlah subjek penelitian sebanyak 51 pasien. Pengumpulan data dilakukan dari beberapa puskesmas yang tersebar di lima kabupaten/ kota di Pulau Lombok pada tahun 2021. Analisis data menggunakan uji hipotesis korelatif koefisien kontingensi melalui SPSS 28,0. Hasil: Dari 51 subjek, ditemukan 30 di antaranya memiliki gambaran sitologi Well-organized Granuloma dan 21 lainnya memiliki gambaran sitologi Poorly-organized granuloma. Nilai P value antara gambaran sitologi dengan berat badan setelah terapi adalah 0.263 dengan nilai korelasi sebesar 0.223. Nilai P value antara gambaran sitologi dengan ukuran nodul setelah terapi adalah 0.054 dengan nilai korelasi sebesar 0.928 Kesimpulan: Tidak terdapat hubungan yang signifikan antara gambaran sitologi menggunakan metode FNAB dengan respons terapi pada pasien limfadenitis tuberkulosis di pulau Lombok. Kata Kunci: Limfadenitis Tuberkulosis, FNAB, Gambaran Sitologi, Respons Terapi, dan Lombok
Pengaruh Intensitas Pruritus terhadap Kualitas Hidup Pasien Psoriasis Vulgaris di RSUD Provinsi NTB Ayu Niti Wedayani Anak Agung; Dedianto Hidajat
Unram Medical Journal Vol 11 No 4 (2022): volume 11 no 4
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i4.800

Abstract

Latar Belakang: Psoriasis merupakan penyakit sistemik berupa inflamasi kronis pada kulit dengan karakteristik berupa plak merah yang berbatas tegas dengan adanya skuama tebal sebagai hasil proses dari gangguan proliferasi dan diferensiasi lapisan epidermis. Psoriasis tidak mengancam jiwa, namun dapat mempengaruhi kualitas hidup pasien Tujuan: Penelitian ini bertujuan ntuk mengetahui adanya hubungan dampak intensitas pruritus terhadap kualitas hidup pasien psoriasis di Kota Mataram. Metode: Penelitian ini merupakan studi potong lintang untuk mengetahui pengaruh intensitas pruritus terhadap kualitas hidup pasien psoriasis pada periode 2019-2020. Data pasien psoriasis diperoleh dari RSUD Provinsi NTB. Intensitas pruritus diukur dengan VAS dan 5D. Kualitas hidup dinilai menggunakan DLQI. Hasil: Ada hubungan yang signifikan antara intensitas pruritus dengan kualitas hidup pasien psoriasis yang dapat dilihat dari nilai P=0.006<0.05. Berdasarkan intensitas pruritus didapatkan derajat keparahan VAS kategori sedang yaitu 29 responden (42.6%) dan 5D kategori moderate yaitu 36(52.9%), serta kualitas hidup terpengaruh sedang pada 28 responden (41.2%). Kesimpulan: Berdasarkan hasil penelitian, didapatkan adanya hubungan antara intesitas pruritus dengan kualitas hidup pasien psoriasis di Kota Mataram. Berdasarkan karakteristik VAS dan 5D didapatkan intensitas purirtus yang sedang, diikuti dengan sebagian besar pasien psoriasis vulgaris memiliki kualitas yang berpengaruh sedang (moderate effect) terhadap kehidupan pasien
Tatalaksana Non-Acetaminophen Induced Acute Liver Failure Dengan Menggunakan N-acetylcysteine Mia Putri Sahara
Unram Medical Journal Vol 11 No 4 (2022): volume 11 no 4
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i4.801

Abstract

Gagal hati akut adalah suatu kondisi di mana terjadi disfungsi hati akut. Ada dua jenis gagal hati akut, yaitu gagal hati akut yang diinduksi asetaminofen dan gagal hati akut yang diinduksi non-asetaminofen. Gagal hati akut memiliki angka kejadian 1-6 kasus per 1 juta orang setiap tahunnya di negara maju, sedangkan untuk negara berkembang penilaiannya diperkirakan angka kejadiannya lebih besar karena memiliki angka kejadian hepatitis yang tinggi, di Amerika diperkirakan sebesar sebanyak 2500 kasus gagal hati akut per tahun. Sampai saat ini, tidak ada pengobatan yang efektif untuk gagal hati akut yang tidak disebabkan oleh asetaminofen selain transplantasi hati. Berdasarkan hasil analisis penelitian yang dilakukan, pengobatan terapeutik N-acetylcysteine ????(NAC) pada gagal hati akut yang diinduksi non-asetamin terbuka dapat menjanjikan.
Hubungan antara Umur dengan Ekspresi MIF (Macrophage Migration Inhibitory Factor) pada Penderita Limfadenitis Tuberkulosis Nimas Resti; Fathul Djannah; Philip Habib
Unram Medical Journal Vol 11 No 4 (2022): volume 11 no 4
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i4.803

Abstract

Abstrak Latar belakang: Prevalensi TB ekstra paru pada tahun 2019 dilaporkan mencapai sekitar 16% dari 7,1 juta kasus kejadian TB di dunia. Di Indonesia dengan insidensi tinggi tuberkulosis, limfadenitis tuberkulosis merupakan kasus tersering dari TB ekstra paru. MIF (Macrophage Migration Inhibitory Factor) merupakan salah satu sitokin yang berperan dalam mempengaruhi ketahanan tubuh pasien limfadenitis TB. Kadar MIF pada setiap tingkatan umur berbeda-beda, mulai dari lahir hingga dewasa. Terdapat perbedaan hasil dari penelitian-penelitian sebelumnya terkait hubungan antara umur dengan ekspresi MIF, beberapa menyatakan keduanya memiliki hubungan, sedangkan yang lainnya menyatakan sebaliknya. Oleh karena itu, penelitian ini bertujuan untuk mengetahui hubungan antara umur dengan ekspresi MIF (Macrophage Migration Inhibitory Factor) pada penderita limfadenitis tuberkulosis. Metode: Desain penelitian menggunakan rancangan penelitian deskriptif analitik dengan pendekatan cross-sectional. Pemilihan sampel menggunakan consecutive sampling, yang diperoleh dari data rekam medis penderita limfadenitis tuberkulosis di Nusa Tenggara Barat berupa sampel blok parafin. Besar sampel penelitian berjumlah 100 orang dengan analisis statistik menggunakan uji korelasi rank spearman. Hasil: Total subjek penelitian berjumlah 100 orang, 54 sampel perempuan dan 46 sampel laki-laki. Penelitian ini didominasi oleh responden dengan rentang umur 20-60 tahun (74,0%), lalu diikuti oleh rentang umur 11-19 tahun (16,0%). Immunoreactive score yang dominan dalam penelitian ini yaitu IRS 1 (43,0%). Hasil dari uji korelasi spearman didapatkan nilai p= 0.567 dan (r didapat) < r minimal (0,4). Kesimpulan: Tidak terdapat hubungan antara umur dengan ekspresi MIF (Macrophage Migration Inhibitory Factor) pada penderita limfadenitis tuberkulosis. Kata kunci: MIF (Macrophage Migration Inhibitory Factor), umur, limfadenitis tuberkulosis, immunoreactive score, pewarnaan IHC.
Paraplegia Inferior Tipe UMN sebagai Manifestasi Klinis pada Pasien Spondilitis dengan Penyebab Infeksi Nonspesifik: Laporan Kasus Ni Wayan Ananda Hening Mayakosa
Unram Medical Journal Vol 11 No 4 (2022): volume 11 no 4
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i4.804

Abstract

Spondylitis with nonspecific infectious causes is a destructive infection of the spine or paraspinal structures due to nonspecific infectious agents. The development of spondylitis can result in destruction of the vertebrae and widespread inflammation into the epidural and paraspinal spaces. This can lead to spinal cord damage and other neurological complications, one of which is inferior paraplegia. The following is a case report of a 56-year-old man with clinical signs and symptoms and neurological deficits including low back pain with gradual onset, inferior paraplegia of the upper motor neuron (UMN) type with progressive gradual onset, and parahypoesthesia and parahypoalgesia at the level of the thoracic myelum segment 7. In the early stages of disease evaluation, these clinical signs and symptoms lead to a possible diagnosis of a myelum tumor with a differential diagnosis of tuberculous spondylitis. The results of bone tissue biopsy taken during surgery, it turned out that there was chronic inflammation that supported the diagnosis of infectious spondylitis with non-specific causes.
Effectiveness of Betahistine in the Management of Vertigo Ath-Thariq Ramadhan; Ilsa Hunaifi
Unram Medical Journal Vol 11 No 4 (2022): volume 11 no 4
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i4.812

Abstract

Vertigo is an illusion of self-movement or environmental movement. This symptom produces some sensation of disorientation in space and is accompanied by vegetative disturbances (nausea, vomiting, sweating) or auditory symptoms (hearing loss, tinnitus, ear fullness). Benign paroxysmal positional vertigo (BPPV), Ménière's disease, and vestibular neuritis are common cases in clinical practice. Treatment of vertigo usually includes the use of medication, physical therapy, and lifestyle adaptations. The most commonly used pharmacological modality is betahistine for the treatment of Ménière's disease and BPPV. Betahistine has activity modulating the histaminergic system, causing vasodilation and improving blood flow to the cochlea, thereby improving vertigo symptoms.
POTENSI OMEGA-3 BULU BABI (SEA URCHIN) DALAM KONTROL PROGRESIVITAS DEMENSIA ALZHEIMER Arina Windri Rivarti
Unram Medical Journal Vol 11 No 4 (2022): volume 11 no 4
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i4.838

Abstract

With the increasing prevalence of Alzheimer's dementia and the lack of effectiveness of existing drugs in inhibiting the progression of the disease, the investigation of new drug candidates will continue. Omega-3 fatty acids, especially docosahexaenoic acid (DHA), are compounds that can be used as drug candidates for this purpose. Recent scientific evidence, both from epidemiological studies and preclinical trials in experimental animals, shows the potential of these compounds in maintaining cognitive function and inhibiting the progression of Alzheimer's dementia through various mechanisms, including anti-inflammatory, anti-amyloidogenic, and brain neuroplasticity. These compounds are contained in various marine organisms, including sea urchins. Given the wide availability of marine life on the coast and its ability to biosynthesis of omega-3 fatty acids, this marine biota can be considered as the main source of omega-3 in the development of omega-3 as a drug for the protection of cognitive function in Alzheimer's disease dementia.
Comparing Flexible Ureteroscopy and Percutaneous Nephrolithotomy for Lower Pole Stone Pandu Ishaq Nandana; M. Hairul Umam
Unram Medical Journal Vol 11 No 4 (2022): volume 11 no 4
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i4.840

Abstract

A total of 10 comparative studies involving 1241 participants with lower pole calyx stone size 1.0 – 3.0 cm were included for this systematic review. Our review found out that stone free rate PCNL procedure range around 83.3% - 98.3% and FURS procedure range around 78.6% - 93.2%; operative time of PCNL procedure range around 46.2 + 24.3 to 85.5 + 41.1 minutes meanwhile FURS procedure range around 55.8 + 11.4 to 123.0 + 57.4 minutes; hospital stay of PCNL procedure range around 0.3 + 0.04 to 5.3 + 1.20 days and hospital stay of FURS procedure range around 0.16 + 0.04 to 3.2 + 0.52 days; and complications rate after PCNL procedure range around 4.4% - 25% and after FURS procedure range around 4.6% - 21.6%. Most of studies shown that PCNL procedure have higher stone free rate, shorter operative time, longer hospital stays and higher complications rate compared against FURS procedure.
GAMBARAN KASUS KEGAWATDARURATAN PASIEN SERANGAN HEWAN DI INSTALASI GAWAT DARURAT (IGD) RUMAH SAKIT SAIFUL ANWAR MALANG TAHUN 2012-2016, 2021, DAN 2022 Munsifah Zaiyanah; Taufiq Abdullah; Anom Josafat
Unram Medical Journal Vol 11 No 4 (2022): volume 11 no 4
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i4.841

Abstract

Background Indonesia as a tropical country with thousands of islands is one of the most diverse populations of animals in the world. Some of them are harmful towards humans. The research aim is to know and review the incidents of animal attacks that were reported to Saiful Anwar Hospital, Malang. The Method using a descriptive research method. Sample taken between 2012-2016, 2021, and 2022. The total of the sample is 362, all of which are patients that came to the ER of Saiful Anwar Hospital, Malang with complaints of animal attacks. The Results In the gender variable, there are 253 men and 109 women.. In the complaints variable, pain is the most frequent complaint, with 178 cases reported, followed by swelling 122 cases, 120 wound cases, 12 dizzy cases, 11 nauseous cases, 6 itchiness cases, 3 general weakness cases, and 2 diarrhea cases. In age variables, 260 patients were 18-60 years old, followed by 70 patients aged <18 years old, 32 patients >60 years old. The triage variables results are 120 patients sorted as green, 239 as yellow, and 3 as red. The cause of the attacst are 268 snake cases, followed by 36 unidentified cases, 24 dog cases, 17 scorpion and feline caused, and 3 monkey cases. Conclusion: The incident of animals attack tend to decrease every year, mostly man was the victim with age of 18-60 years old. The most frequent animal that cause the bite was snake, and P2 was the most cases in the ED

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