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Mutiara Medika: Jurnal Kedokteran dan Kesehatan
Published by Universitas Muhammadiyah Yogyakarta
ISSN : 14118033     EISSN : 26140101     DOI : 10.18196/mm
Core Subject : Health,
Health Professions Medicine & Pharmacology
Jurnal Mutiara Medika Fakultas Kedokteran dan Ilmu Kesehatan (MMJKK) Universitas Muhammadiyah Yogyakarta is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, and community or public health research to integrate researches in all aspects of human health.
Arjuna Subject : -
Articles 934 Documents
 86   87   88   89   90 
Determination of Stunting Risk Factors Using Spatial Interpolation Geographically Weighted Regression Kriging in Malang Henny Pramoedyo; Mudjiono Mudjiono; Adji Achmad Fernandes; Deby Ardianti; Kurniawati Septiani
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 20, No 2 (2020): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.200250

Abstract

Stunting is the condition toddlers have Stunting is the condition toddlers have less length or height if compared to age. The high percentage of stunting is influenced by several factors, namely access to healthy latrines, quality drinking water, hand washing behavior with soap, coverage of posyandu access and coverage of breast milk 1-6 months, and there are indications that if an area has a high stunting percentage, then there is a possibility that the nearest area has the same condition. So, the statistic method for this research use the spatial interpolation Geographically Weighted Regression Kriging. Geographically Weighted Regression (GWR) is a weighted regression in which the weighting function is used to describe the closeness of relations between regions. The weight used is distance based weight dan weighting by area (contiguity). Ordinary kriging method calculated with semivariogram which is one function to describe and model the spatial autocorrelation between data of a variable and function as a measure of variance. The results showed that based on value GWR model with weight Fixed Gaussian Kernel better to use then the weighted GWR model Rook Contiguity. The Predicted of prevelensi stunting in the form of map based on interpolation GWR Kriging. Keywords: Stunting, GWR, and Kriging.
Immunocytochemical Study of Rabbit-Polyclonal to Mycobacterium Tuberculosis, AB905: Improving Diagnostic of Tuberculous Lymphadenitis Humairah Medina Liza Lubis; Emni Purwoningsih; Ance Roslina; Muhammad Al Anas
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 21, No 2 (2021): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v21i2.11559

Abstract

Tuberculous lymphadenitis (TBLN) is the most common form of extrapulmonary tuberculosis. However, the optimal diagnosis using Fine-Needle Aspiration Cytology (FNAC) or excisional biopsy is uncertain. This research aims to improve the diagnostic of TBLN with FNAC and immunocytochemistry (ICC) compared to the response to antituberculosis therapy. The cross-sectional study involved 43 patients with the criteria for TBLN diagnosis based on the appropriate clinical history of tuberculosis and indicative cytological results. Immunocytochemical examination employed rabbit-polyclonal to Mycobacterium tuberculosis (MTB) antibody (AB905). The MTB expression was found in 35 out of 43 cases (81%) that appropriate cytological features of the tuberculosis process. Meanwhile, eight out of 43 cases (19%) did not express MTB. Diagnostic tests for lesions with a positive cytologic appearance of TBLN and ICC were compared to the response to anti-tuberculosis therapy, revealing the sensitivity, specificity, positive predictive value, and negative predictive value of 95.2%, 75%, 95.2%, and 17%, respectively. Besides, Fisher's exact tests utilized to identify the relationship between two variables; p 0.05 was considered significant. This research found immunocytochemical study was a sensitive and specific tool for improving the diagnostic of TBLN.
Life Quality of Pediatric Patient with Dengue Hemorrhagic Fever (DHF) Who Received Crystalloid and Colloid Fluid Treatment in PKU Muhammadiyah Hospital Yogyakarta Chotijatun Nasriyah; Dyah Aryani Perwitasari; Nurcholid Umam Kurniawan
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 19, No 2 (2019): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.190229

Abstract

Dengue hemorrhagic fever (DHF) in the community can have an impact of panic, death, and reduced age of hope in the family. Research on the quality of life of DHF pediatric patient who got the treatment of crystalloid and colloid fluids has never been done before. The purpose of this study was to determine the quality of life of DHF pediatric patients who received crystalloids and colloids with PedsQL instruments. The study design was a cohort with block randomization. The inclusion criteria in this study were hospitalized DHF pediatric patients aged one month -18 years from February to May 2018. The exclusion criteria were DHF patients who came with referrals from other hospitals who had received fluid therapy. Research data include the length of stay (LOS) and quality of life score with the PedsQL questionnaire. The statistical analysis was using an independent t-test and the Mann Whitney test. The length of stay for the crystalloid group is five days longer than the colloid group, which is four days. From a total of 48 subjects studied, the score for the physical function of the crystalloid fluid group 84.54 ± 9.90 was higher than the colloid group of 77.58 ± 19.30 (p = 0.125). The emotional functions in the crystalloid group obtained a score of 81.88 ± 12.14 higher than the colloid group, i.e., 79.17 ± 18.5 (p = 0.552). The social function in the crystalloid group had a score of 92.08 ± 8.84 higher than the colloid group of 86.67 ± 13.96 (p = 0.232). The school functions in the crystalloid group had a score of 50.42 ± 33.68 higher than in the colloid group of 37.92 ± 36.62 (p = 0.225). The results of this study showed that the crystalloid group had a higher quality of life score compared to the colloid group, although it was not significant. 
Persepsi dan Sikap Dokter dalam Pemberian Surat Keterangan Cuti Sakit di RS PKU Muhammadiyah Yogyakarta Dirwan Suryo Soularto; Ayu Azhimsari
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 8, No 2 (s) (2008): Oktober
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v8i2 (s).1637

Abstract

Doctor statement letter is a letter which is given by doctor professionally about a certain situation which is known and can be proven it’s truth. The aim of this research is to know the factors which influent the perception and behavior of doctor to give the sickness permission letter. The design of the research is non experimental. The subject of research is some doctors who work in PKUM uhammadiyah Hospital of Yogyakarta are 35 people. Responden who fulfill questioner about perception and attitude of doctor to give sickness permission letter. The analysis descriptive which is used with cross-sectional approach. The result of research is 63% agree every patient get a sickness permission letter, 60% disagree about the relation of friendship which influent the doctor to give sickness permission letter, 94% agree about the giving of period of sickness is a right of doctor absolutely, 71% disagree if doctor always give sickness permission letter to every patient who asked it, 74% doctor never give sickness permission letter which isn ’t suitable with the patient ’s condition, 60% doctor agree to give period of retirement sickness sometimes thinks the patient’s requirement, 97% doctor disagree to ask a certain free to give sickness permission letter. The conclusion of this research is perception and attitude of doctor in Muhammadiyah Hospital of Yogyakarta still suitable with etic of Indonesion medical.Surat keterangan dokter adalah surat yang diberikan oleh seorang dokter secara profesional mengenai keadaan tertentu yang diketahuinya dan dapat dibuktikan kebenarannya. Penelitian ini bertujuan untuk mengetahui faktor-faktor yangmempengaruhi persepsi dan sikap dokter dalam pemberian surat keterangan cuti sakit. Desain penelitian ini adalah non-eksperimental dengan pendekatan cross-sectional. Subyek penelitian adalah 35 orang dokter yang bekerja di RS PKU Muhammadiyah Yogyakarta. Responden mengisi kuesioner mengenai persepsi dan sikap dokter dalam memberikan surat keterangan cuti sakit. Hasil kuisioner dianalisa secara deskriptif. Hasil penelitian didapatkan 63% setuju setiap pasien mendapatkan surat keterangan cuti sakit, 60% tidak setuju hubungan kekerabatan mempengaruhi dokter dalam memberikan surat keterangan cuti sakit, 94% setuju pemberian lama cuti sakit merupakan hak/ kewenangan mutlak dokter, 71% tidak setuju jika dokter selalu memberikan surat keterangan cuti sakit kepada setiap pasien yang meminta, 74% dokter tidak pernah memberikan surat keterangan cuti sakit yang tidak sesuai dengan kondisi pasien, 60% dokter setuju dalam memberikan lama cuti sakit kadang-kadang mempertimbangkan permintaan pasien, 97% dokter tidak setuju menarik biaya tersendiri dalam pemberian surat keterangan cuti sakit. Disimpulkan bahwa persepsi dan sikap dokter di RS PKU Muhammadiyah Yogyakarta masih sesuai dengan kode etik kedokteran Indonesia.
Pewarnaan Gigi Buatan untuk Keperluan Penelitian Erlina Sih Mahanani
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 8, No 2 (2008)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v8i2.1480

Abstract

Nowadays, regarding the increased of aesthetic demands, the dental staining is a common problem. It can be caused by exogenous or endogenous source. It may adhere directly to the surface, contain within calculus and soft deposit, or incorporate within the tooth structure. Many studies are conducted to evaluate the ability of material or herbal to remove or inhibit dental staining. Therefore it is needed a method to produce the artificial stain for specimen.This article has an objective to give information about the artificial dental stain for research. Combination between chlorhexidine and tea has been reported that it can produce fast and optimum artificial stain. Meanwhile it is needed artificial saliva to stimulate pellicle in the specimen surface so the stain source can attach. The clear acrylic block is used as a specimen and spectrophotometer for measuring the optical density of staining and Lobene score index for visual assessment. Pewarnaan gigi adalah masalah yang seringteijadi, bisa disebabkan faktor dari dalam maupun dari luar, dan dapat bersifat sementara di permukaan, bersatu dengan karang gigi ataupun telah masuk dalam struktur gigi. Banyak penelitian dilakukan untuk mengetahui kemampuan suatu bahan untuk mengurangi atau mencegah terjadinya pewarnaan gigi. Oleh sebab itu diperlukan suatu metoda penelitian untuk menghasilkan pewarnaan buatan pada spesimen.Tujuan penulisan artikel ini adalah untuk memberikan suatu gambaran metoda pewarnaan gigi buatan untuk keperluan penelitian. Kombinasi antara teh dan obat kumur chlorhexidine telah banyak diteliti dapat menghasilkan pewarnaan yang cepat dan optimal. Selain itu diperlukan saliva buatan untuk menghasilkanpellicle di permukaan spesimen sehingga sumber pewarna bisa menempel. Digunakan akrilik jernih sebagai spesimen dan spektrofotometer untuk mengukur optical density pewarnaan gigi dan Lobene skor indek untuk penilaian visual.
Modifikasi Protein Akibat Pembebanan Glukosa dengan Model Reaksi Glikosilasi Nonenzimatik in vitro Eko Suhartono; Bambang Setiawan; - Mashuri; Maya Juniarti; Insanul Kamilah; - Haudhiya
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 8, No 1 (2008)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v8i1.1653

Abstract

Glycocylation reaction causes protein modification. Glycocylation is a reaction between aldehyde group from reducing sugar with amine group of protein. The aim of this study was to measure Advanced Glycation End Products (AGEs) formation, dicarbonyl compound and tyrosine degradation in glycocylation reaction in vitro. A quasi experimental study was done to four treated groups, i.e. P1= 5 ml Bovine Serum Albumin (BSA), 10 ml phosphate buffer dan 10 ml aquadest; P2= 5 ml BSA, 10 ml phosphate buffer and 10 ml glucose 125 mM; P3= 5 ml BSA, 10 ml phosphate buffer and 10 ml glucose 250 mM; P4= 5 ml BSA, 10 ml phosphate buffer and 10 ml glucose 500 mM. AGEs compound was measured for 21 days using spectrophotometer at X = 390 nm. Dicarbonyl compound was measured by DNPH odification methods at X = 470 nm. Tyrosine degradation was measured usingMillon-Nasse reaction. Anova and Tuckey HSD test concluded there are significant difference between each groups (P0,05). Based on correlation regresion test conclude that the increase of dicarbonyl compounds, AGEs and tyrosine degradation had positive correlation with increase of glucose concentration. Glucose overloading could induce protein modification in vitro.Salah satu penyebab modifikasi protein adalah reaksi glikosilasi. Reaksi glikosilasi adalah reaksi antara gugus aldehid gula pereduksi dengan gugus amina protein. Penelitian ini bertujuan mengukur Advanced Glycation End Products (AGEs), senyawa dikarbonil maupun degradasi tirosin pada reaksi glikosilasi in vitro. Penelitian ini merupakan penelitian eksperimental semu denganpre andpost control group design terhadap empat kelompok perlakuan, yaitu P1= 5 ml Bovine Serum Albumin (BSA), 10 ml buffer fosfat dan 10 ml aquadest; P2= 5 ml BSA, 10 ml buffer fosfat dan 10 ml glukosa 125 mM; P3= 5 ml BSA, 10 ml buffer fosfat dan 10 ml glukosa 250 mM; P4= 5 ml BSA, 10 ml buffer fosfat dan 10 ml glukosa 500 mM. Absorbansi senyawa AGEs diukur selama 21 hari pada X = 340 nm sedangkan absorbansi senyawa dikarbonil diukur dengan X = 390 nm dan absorbansi degradasi tirosin dengan k=470 nm. Pengukuran absorbansi senyawa dikarbonil menggunakan metoda DNPH yang dimodifikasi, sedangkan pengukuran degradasi tirosin menggunakan reaksi Millon-Nasse. Berdasarkan hasil uji Anova dan Beda Nyata Jujur, disimpulkan bahwa terdapat perbedaan yang signifikan (P0,05) tiap kelompok perlakuan. Berdasarkan uji korelasi regresi dapat disimpulkan bahwa pembentukan senyawa dikarbonil, AGEs dan degradasi tirosin berkorelasi positif dengan peningkatan konsentrasi glukosa. Pembebanan glukosa yang berlebih dapat memicu modifikasi protein in vitro.
Antioxidant Activity Potential of Red Pomegranate (Punica granatum L.) Peel as Herbal Tea Prima Vina Resti; Sri Utami; Muhammad Arsyad
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 20, No 2 (2020): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.200245

Abstract

Latar Belakang: Diet yang tidak sehat, gaya hidup yang tidak sehat, kebiasaan yang salah, polusi lingkungan, radiasi, sinar ultraviolet (UV)UV, asap rokok, dan stress merupakan sumber radikal bebas. Buah delima merah (Punica granatum L.) adalah salah satu sumber antioksidan polifenol, khususnya punikalagin (elagitanin) yang telah dibuktikan memiliki aktivitas antioksidan yang kuat, antiinflamasi, dan antikarsinogenik pada beberapa penelitian. Pada penelitian ini dilakukan pengolahan kulit delima merah menjadi teh sebagai antioksidan. Dalam Al-Quran, buah delima merah disebut beberapa kali sebagai bentuk nikmat dari Allah SWT untuk menjaga kesehatan karena manfaatnya yang banyak.Tujuan: Mengetahui aktivitas antioksidan pada seduhan teh dari kulit delima merah yang diujikan dengan metode DPPH dan mengetahui tinjaunnya menurut pandangan Islam. Metode: Kulit delima merah dikeringkan, kemudian dipotong kecil-kecil, dan digerus dengan menggunakan blender agar mendapatkan bubuk kulit delima merah. Sebagian bubuk kulit delima merah yang telah diperoleh diseduh dengan air mendidih 100° C. Sisa bubuk kulit delima merah dimaserasi dengan etanol 70% kemudian disaring dan filtratnya dipekatkan menggunakan vacuum rotary evaporator sehinga didapatkan ekstrak kental. Masing-masing sampel diukur aktivitas antioksidannya metode DPPH.Hasil: Aktivitas antioksidan dinyatakan dengan nilai IC50. Nilai IC50seduhan teh dari kulit delima merah adalah 17,59 ppm, ekstrak etanol kulit delima merah 9,58 ppm, dan asam askorbat 2,98 ppm.Kesimpulan: Seduhan teh dari kulit delima merah dan ekstrak kulit delima merah mempunyai aktivitas antioksidan yang sangat kuat. Ekstrak kulit delima merah memiliki aktivitas antioksidan yang lebih tinggi dari seduhan teh dari kulit delima merah. Penelitian ini sejalan dengan perintah Allah SWT untuk memanfaatkan seluruh kekayaan alam dalam hal kebaikan seperti menjaga kesehatan tubuh agar dapat menjalankan kewajiban keagamaan.
The Duration of Reading the Qur'an with the Stress Levels in Medical Faculty Students in Palembang Ahmad Ghiffari; Syahrul Muhammad; M. Avif Ababil
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 21, No 1 (2021): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v21i1.8488

Abstract

The level of stress in each education programs differ between medical students and other scholars. Students should able to cope to normalize their stress. The study aims to determine the relationship between the duration of reading the Qur'an with the level of stress on students. The study design was a cross-sectional study, with a simple random sampling. The collecting data technique was using the Depression Anxiety Stress Scale (DASS) questionnaires and duration questionnaires followed by the chi-square analysis. The respondents are 90 medical students of Universitas Muhammadiyah Palembang. The results showed that the duration of reading the Qur'an among students is poor, and the moderate duration is correlated with a good stress level (p=0,002). Concluded that there is a relation to the duration of reading The Qur'an with the level of stress in medical students.
The Presence of House Dust Mites in Residences and Classrooms of Students with Allergic Rhinitis Suri Dwi Lesmana; Harianto Harianto; Reyza Octarient
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 21, No 2 (2021): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v21i2.10975

Abstract

Allergy is still a health problem in Indonesia. One of the manifestations of allergies is allergic rhinitis. Many factors can trigger the recurrence of rhinitis, including exposure to house dust mites. This study aims to identify the population of house dust mites in the classrooms and student residences. This study was participated by 74 FK UNRI students with allergic rhinitis. The samples included dust collected from residences and classrooms consisting of four large classrooms, three small classrooms, four laboratories, two examination rooms, 12 skills lab rooms, and 15 tutorial rooms. Detection of dust was performed using the direct method. The results showed that no classroom (0%) was found with house dust mites. However, there were 37.8% of residences were positive. Based on the result, it can be concluded that the high population of house dust mites in the students’ residences becomes an essential factor as a chronic stressor for allergic rhinitis.
The Effect of Sunnah Fasting on Blood Pressure and Oral Hygiene Level Erlina Sih Mahanani; Hana Aulia Hapsari; Dinda Triani Ahyati
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 22, No 2 (2022): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v22i2.13721

Abstract

The Monday-Thursday fasting, as one of the sunnah highly recommended by Rasulullah, can be a key to maintaining health. This research aims to determine the difference in blood pressure and oral health among the santriwati in Madrasah Mu’allimat Muhammadiyah Yogyakarta who have gotten used to doing and those who have not gotten used to doing Monday-Thursday fasting. It is an observational quantitative research using a cross-sectional design. They were 48 santriwati of 14-18 years old as subjects. Blood pressure was measured thrice with a minimum measurement interval of 15 minutes. The dental and oral hygiene level was obtained using the OHI-S measurement index. The students who habitually carried out sunnah fasting had a normal blood pressure of 20.8% (of a total of 27.1%), and all students had a good level of OHI (27.1%). Meanwhile, among students who are not accustomed to fasting, 45.8% had abnormal blood pressure (a total of 72.9%), and the good level of OHI was only 47.9%. The analysis of Mann-Whitney data showed a significant value for the blood pressure category variable of 0.015 and the OHI-S category of 0.015. The significance level of p 0.05 for each measurement variable (blood pressure and OHI-S categories) illustrated that there were differences in blood pressure and oral hygiene among the santriwati who had gotten used to doing and those who had not gotten used to doing Monday-Thursday fasting.

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