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Mutiara Medika: Jurnal Kedokteran dan Kesehatan
Published by Universitas Muhammadiyah Yogyakarta
ISSN : 14118033     EISSN : 26140101     DOI : 10.18196/mm
Core Subject : Health,
Health Professions Medicine & Pharmacology
Jurnal Mutiara Medika Fakultas Kedokteran dan Ilmu Kesehatan (MMJKK) Universitas Muhammadiyah Yogyakarta is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, and community or public health research to integrate researches in all aspects of human health.
Arjuna Subject : -
Articles 934 Documents
 88   89   90   91   92 
Reading Holy Qur’an to Improve Verbal Fluency in Elderly Siti Munawaroh; Yunia Hastami; Adji Suwandono; Hartono Hartono; Ari Natalia Probandari; Fitriana Herawati; Ummu Ma’rifatul Afifah; Aldira Ayu Nastiti Nur Hanifah
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 23, No 1 (2023): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v23i1.15160

Abstract

The high prevalence of dementia that impairs verbal fluency has been a global source of concern. As a result, strategies for preserving or improving verbal fluency in the elderly are required. A neuroplasticity-based reading program has been shown to improve verbal fluency. This study aims to ascertain whether reading the Holy Qur'an has an effect on an older adult's ability to communicate fluently. It is an experimental study with a quasi-experimental design with pretest-posttest control groups. This study sampled 22 elderly individuals with the following criteria: age greater than 60 years, ability to speak and read the Holy Qur'an, a Mini-Mental State Examination (MMSE) score greater than 24, absence of psychiatric disorders, absence of head trauma, and absence of neurological disease. The intervention group read the Quran for two weeks, while the control group did not. Both groups were measured for Verbal fluency at the beginning and after the intervention. There were significant differences in post-test phonemic scores between the control group (CG) and the intervention group (IG) (p=0.019). Meanwhile, there was no significant difference in semantic score in all groups (p0.852). Reading the Holy Qur’an activity intervention for two weeks affected verbal fluency in the elderly by increasing phonemic but not semantic scores.
The Correlation between Various Types of Antihypertensive Drugs and the Incidence of Acute Stroke Athiyya Salma Hamida; Tri Wahyuliati
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 23, No 1 (2023): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v23i1.13955

Abstract

Stroke is the second leading cause of death and the third leading cause of disability, whose incidence increase with hypertension. Various antihypertensives are used as secondary therapy for stroke. However, the effectiveness of each drug is still debated. This study aims to determine the correlation between various types of antihypertensive drugs on the incidence of acute stroke. This research is a cross-sectional study. Inclusion criteria included hypertensive patients who had used antihypertensive drugs for at least a year and were aged 36. We included 78 subjects, 47 men and 31 women. The drugs were ACEI + CCB (13), ARB (8), ARB + CCB (22), and CCB (35). The subject had an ischemic stroke (8) and a hemorrhagic stroke (1). The logistic regression test showed ACEI + CCB as a reference category. The result consecutively showed ARB (OR, 4.95; CI, 0.72 to 33.89; p = 0.103), CCB (OR, 2.61; CI, 0.39 to 17.01; p = 0.317), and ARB + CCB (OR, 2.36; CI, 0.19 to 29.75; p = 0.507). The antihypertensive drugs had no significant correlation with the incidence of acute stroke. It indicated that stroke risk was not triggered by antihypertensive and could effectively control hypertension and protect patients against stroke
Self-Management and Quality of Life in Diabetic Type II Patients at Mataram University Hospital Luh Komang Diah Lakhsmi Paramita; Seto Priyambodo; Rifana Cholidah
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 23, No 1 (2023): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v23i1.16320

Abstract

Type 2 diabetes mellitus (DM) is the community's most common metabolic disease, indicated by increased blood glucose. Patients with type 2 DM cannot be cured but can be controlled by self-management. Self-management improves the quality of life (QoL) by increasing the quality of metabolic control and reducing the risk of hospitalization and mortality complications of type 2 DM. This study aims to examine the relationship between self-management and the QoL among patients with type 2 DM at the Mataram University Hospital. This study used a cross-sectional analytic method, and the population included outpatients with type 2 DM in Mataram University Hospital. This study employed 40 people selected by the consecutive sampling method and got interviewed to fill out the Diabetes Self-Management Questionnaires (DSMQ) and Asian Diabetes Quality of Life (Asian DQOL) questionnaires. The data analysis used the Spearman statistical test. The majority of the self-management respondents were good (87.5%), and the QoL (95%). The results obtained a p-value of 0.000 (p0.05), indicating a significant relationship between self-management and the QoL of type 2 DM patients in Mataram University Hospital. This result showed that the better the self-management of type 2 DM patients is, the better their QoL will be.
Antimicrobial Activity of Pecut Kuda Leaf Extract (Stachytarpheta jamaicensis (L. Vahl) against Mycobacterium smegmatis Putri Nadia Ramadhani; Ika Dyah Kurniati; Maya Dian Rakhmawatie
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 23, No 1 (2023): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v23i1.15599

Abstract

Mycobacterium smegmatis infrequently causes infection, but it is easy to be pathogenic in immunosuppressed patients. Many reported that M. smegmatis resistance to several antibiotics became an impetus for searching for new antimicrobials. Therefore, this study aims to prove the effect of Pecut Kuda leaf extract (Stachytarpheta jamaicensis (L.) Vahl) on the growth of M. smegmatis mc2 155. This research is an experimental study with a post-test control group design. The susceptibility test was carried out using the two-fold microdilution method and resazurin staining. The concentration of Pecut Kuda leaf ethanol extract was prepared in the concentration range of 10000.0 – 625.0 µg/ml.  Phytochemical analysis of the content of saponins, tannins, flavonoids, and alkaloids was also carried out on Pecut Kuda leaf ethanol extract. Pecut Kuda leaf ethanol extract can inhibit the growth of M. smegmatis with a minimum inhibitory concentration (MIC) of 5000 µg/ml (very weak activity) because, at the highest concentration of 10000 µg/ml, M. smegmatis still cannot be killed. Furthermore, Pecut Kuda leaf ethanol extract contains saponins, tannins, flavonoids, and alkaloids which are known to have antibacterial activity. However, further evaluation is needed to maximize the antibacterial activity of Pecut Kuda leaf extract, for example, by fractionating the extract.
The Pattern of Intraocular Pressure After Phacoemulsification Surgery In Senile Cataract Nur Shani Meida; Ahmad Ikliluddin; Yunani Setyandriana; Vania Rahmawati
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 23, No 1 (2023): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v23i1.15570

Abstract

Phacoemulsification is a surgical procedure for cataracts, which can increase intraocular pressure (IOP) and cause blindness due to glaucoma. It was known that the pattern of IOP changes after phacoemulsification surgery in senile cataracts. This study was an observational analytic study without a control group design. The study population was male and female senile cataract patients over 40 years of age who underwent phacoemulsification surgery at Kebumen Eye Centre Clinic in 2020. Intraocular pressure measurements using a Noncontact Tonometry by a nurse were carried out before surgery (D-0) and postoperatively on day 2 (D-2), day 9 (D-9), day 16 (D-16), and day- 23 (D-23). The data were analyzed using the Friedman test followed by the Post Hoc LSD test. The Friedman test results showed significant differences (p 0.05) in the IOP measurement at D-0, D-2, D-9, D-16, and D-23. Wilcoxon post hoc test showed IOP measurements on D-2  increased and then decreased normally. There was a change in the IOP pattern after phacoemulsification surgery, in which the IOP increased significantly on D-2 and then decreased normally.
Epithelial Mucosal Changes and An Inflammation Process of the Cavum Nasi Due to Inhaled Sawdust Yusmawati Yusran; Humairah Medina Liza Lubis
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 23, No 1 (2023): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v23i1.16623

Abstract

Woodworkers are particularly susceptible to inhalation of sawdust exposure. Exposure to sawdust for a long time causes various health problems and causes the damage of the epithelium to a barrier. This study aims to identify whether inhaled sawdust can cause changes in the nasal mucosa and the occurrence of an inflammatory process. This study was a cross-sectional analytical study. Data were collected from July 2021 to January 2022 from the nasal cavity swab of 35 woodworkers who had worked for 1 to 5 years. The assessment was carried out by cytological examination to identify epithelial changes in the form of mild and moderate dysplasia, while the inflammation was found in the form of acute and chronic inflammation. Twenty-six (74.3%) samples were normal, 7 (20%) samples had mild dysplasia, and 2 (5.7%) samples had moderate dysplasia. Whereas 20 (57.1%) were found to have no inflammation, 8 (22.9%) were with acute inflammation, and 7 (20.0%) were found to have chronic inflammation). Fisher’s exact test showed a relationship between the inflammatory process and epithelial changes (p 0.020). In conclusion, sawdust inhaled showed changes in the epithelial mucosa and inflammatory processes of the nasal cavity.
The Factors Related to Cadres’ Competency in Integrated Health Service Post during Pandemic Ferry Fadzlul Rahman; Susilo Nur Aji Cokro Darsono; Sri Sunarti
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 23, No 1 (2023): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v23i1.17236

Abstract

The competence of Posyandu (Integrated Service Post) cadres played a crucial role in response to the pandemic. They were responsible for raising awareness about COVID-19 and implementing preventive measures. The impact of their competence cannot be overstated and highlights the importance of investing in health worker training. This study aims to determine the factors related to the competence of Integrated Health Service Post cadres during the pandemic in the Samarinda Primary Healthcare working area. Observational research was employed with stratified random sampling, and primary data was collected from five Primary Healthcare in Samarinda. This study employed three steps to examine the effect of competency cadres: univariate analysis, bivariate analysis using the Spearman Rank test, and multivariate analysis with Multiple Linear Regression. The bivariate analysis results showed that supervision had a very strong correlation with the cadres’ competency, and social environment had a strong correlation with the cadres’ competency. At the same time, the organization had a moderate correlation with cadres’ competency. The multivariate test results showed that the social environment contributed 0.165 times to the competence of cadres, organizational support contributed 0.211 times in cadre competence, and supervision support contributed 0.652 times to cadre competence. It provides them with the necessary resources, training, and recognition for their work.
Improving Cytokines and HDL in Diabetic Wistar Rats by Using Combination of Curcumin and Metformin Dinanti, Fathia Kesuma; Mulyani, Sri Priyantini; Chodidjah, Chodidjah
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 23, No 1 (2023): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v23i1.17031

Abstract

In type 2 diabetes mellitus, lipid profile is often found in the form of high-density lipoprotein (HDL) decrease. TNFa and IL-6 are proinflammatory cytokines that are elevated in the blood in many patients with diabetes mellitus. Turmeric is one of the natural ingredients that have anti-cholesterol and anti-inflammatory effects through the work of its active substance, curcumin. This study aims to evaluate the effect of turmeric extract combined with metformin on HDL, TNFa, and IL-6 levels in diabetic rats. Twenty-four Wistar rats were injected intraperitoneally with streptozotocin and niacinamide. The diabetic rats were divided into control, metformin, turmeric, and combination groups. The dose of metformin and turmeric were given, respectively, 45mg/KgBW/day and 200 mg/KgBW/day. At the same time, the combo group was given a half dose of each. Blood serum was taken to examine the HDL, IL-6, and TNFa levels. The levels of HDL, IL-6, and TNFain diabetic rats that received the combination of metformin and turmeric extract (p0.05) were the best among all the groups. It indicated that the combination of metformin and turmeric was better in increasing HDL and reducing IL-6 and TNFa levels better than metformin or turmeric extract alone.
Correlation Between Platelets Count, Platelet Index and D-Dimer in Covid-19 Patients Nelly Tolla; Rachmawaty Rachmawaty; Andi Salsa Anggeraini; Darmmawaty R; Faidah Nur
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 23, No 1 (2023): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v23i1.16121

Abstract

Hypercoagulation in the alveoli of the lungs is one of the causes of death in SARS-CoV2 virus infection. Hypercoagulation is defined by an elevation in D-Dimer, which typically rises on the fifth day of therapy. This parameter is not available in all hospitals and is still relatively expensive in preventing premature death. Platelets count and indices are suggested to describe the thromboinflammatory condition in COVID-19 patients. This research is an observational analytic study with a cross-sectional study design in 59 COVID-19 patients treated at Hassanuddin University Hospital. The patients who are declared COVID-19 based on the results of radiological examinations and PCR swabs underwent routine blood tests and D-Dimer before undergoing therapy. Data were analyzed using the Spearmen test in SPSS version 26 to reveal the correlation between platelet count, platelet indices, and D Dimer in COVID-19 patients with severe and non-severe conditions.  Platelet count, platelet indices, especially MPV, and D-Dimer values were found to correlate in both groups COVID-19 using the Spearman rho correlation test (p 0.000) with strengths correlation between -44.6 and 60.5. There was a significant association between platelet count and MPV value with D-Dimer in COVID-19 patients.
Association Between Personal Hygiene and Nutritional Status in School-Age Children Andromeda, Andromeda; Rafshanzany, Muhammad Luthfi; Buntoro, Joseph Dharmadi
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 23, No 2 (2023): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v23i2.17848

Abstract

Malnutrition is a global health problem often found in children and adolescents. This condition can inhibit growth and development in children. Soil transmission helminth (STH) infection absorbs nutrients in the host's digestive system, affecting the host's nutritional status. One of the risk factors for STH infection is poor personal hygiene. This study aims to analyze the association of STH infections and personal hygiene with the nutritional status of elementary school children. This research is a cross-sectional study with primary data conducted in August – September 2022 on 92 children aged 6 – 12 years at Neglasari Elementary School, Cilame Village, District Bandung. Nutritional status was assessed by measuring height and weight to calculate body mass index and then putting it into the WHO 2007 Z-Score plotting curve. STH infections were determined by microscopic examination of helminth eggs from feces using the Kato-Katz method. Personal hygiene was assessed through direct interview methods. The results showed that there was no STH infection in all research respondents. The distribution of nutritional status was dominated by normal nutrition, with 66 (71.7%) respondents and the majority had implemented good personal hygiene behavior habits (78 (84.8%) respondents). It can be concluded that there was a significant relationship between personal hygiene and nutritional status in students (p= 0.000). The average score of children who had implemented good personal hygiene was in normal nutritional status.

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