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Berkala Kedokteran
Published by Universitas Lambung Mangkurat
ISSN : 14120550     EISSN : 25485660     DOI : http://dx.doi.org/10.20527
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Berkala Kedokteran is a journal contains scientific articles from original research and literature review in medical and health scope. It is published twice in a year, on February and September.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 478 Documents
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DERAJAT INFILTRASI LIMFOSIT PADA PENDERITA KANKER KOLOREKTAL SUB-TIPE ADENOKARSINOMA Imaduddin, Muhammad Sahal; Oktaviyanti, Ika Kustiyah; Istiana, Istiana
Berkala Kedokteran Vol 11, No 2 (2015): September 2015
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i2.141

Abstract

Cancer is the second leading cause of death which contributes 13% of deaths from a total of 22% of deaths from non-communicable diseases in the world. One contributor to the number of cancer deaths in the world is colorectal cancer. The prognosis of colorectal cancer depend on the stage of cancer at time of diagnosis. However, the prognosis of colorectal cancer can also be determined by looking at the degree of infiltration of lymphocytes in cancer. The purpose of this research is to find out the degree of lymphocytes infiltration in patients with colorectal cancer in Laboratory of Anatomical Pathology Banjarmasin from January to December 2013. The method uses descriptive research by observing the colorectal cancer tissues were obtained from the Laboratory of Pathology Banjarmasin. From a study of 32 samples, found the degree of mild lymphocytic infiltration occurred in 12 patients (37.5%), moderate lymphocytic infiltration occurred in 12 patients (37.5%), and severe lymphocyte infiltration occurred in 8 patients (25%). From this study, found that there are differences in the degree of infiltration of lymphocytes in patients with colorectal cancer. Keywords: Colorectal Cancer, Lymphocyte Infiltration, Prognosis
Hubungan Riwayat Malaria Sebelumnya dengan Kejadian Malaria Berdasarkan Hapusan Darah Pendonor di PT Pama Kecamatan Kintap Putera, Wahyu Aditia Husada; Al Audhah, Nelly; Istiana, Istiana
Jurnal Berkala Kedokteran Vol 10, No 1 (2014): Februari 2014
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i1.930

Abstract

ABSTRACT: Malaria is a disease that is caused by the Plasmodium genus and still become a problem around the world due to high mortality and morbidity. Several types of Plasmodium sp can be transmitted through blood transfusion. The aim of this study was to determine the relationship between history of previous malaria exposure with the event of malaria through donor’s blood smear at PT Pama Kintap subdistrict, Tanah Laut district. It was a survey of analytic-deskriptive study that performed on blood donors by using a questionnaire to see a history of previous malaria, and a smear of blood transfusion donors to see the Plasmodium sp in the blood transfusion. Sample of the research used total sampling method and gained 46 samples. The result was 4 (8.7%) had a previous history of malaria, and 2 (4.3%) was found some Plasmodium sp from their transfusion blood smear. Statistical analyisis used Fischer test, showed p value = 0.006 (p <0.05) which means there is a significant relation between a history of previous malaria exposure with the event of malaria through donor’s blood smear at malaria’s endemic region. Keywords: history of malaria, incident of malaria, blood donor ABSTRAK: Malaria adalah penyakit yang disebabkan oleh Plasmodium dan masih menjadi masalah di seluruh dunia karena angka morbiditas dan mortalitas yang tinggi. Beberapa jenis Plasmodium sp dapat ditularkan melalui transfusi darah. Penelitian ini bertujuan untuk mengetahui hubungan riwayat penyakit malaria sebelumnya dengan kejadian malaria berdasarkan hapusan darah pendonor di PT Pama kecamatan Kintap di kabupaten Tanah Laut. Penelitian ini bersifat survey analitic-descriptive yang dilakukan pada pendonor darah dengan menggunakan kuesioner untuk melihat riwayat malaria sebelumnya, dan hapusan darah transfusi pendonor untuk melihat adanya Plasmodium sp. Sampel penelitian menggunakan teknik total sampel dan mendapatkan 46 pendonor. Hasil penelitian menunjukkan bahwa 4 orang (8,7%) memiliki riwayat malaria sebelumnya, dan 2 orang (4,3%) ditemukan plasmodium dalam hapusan darah transfusinya. Analisis statistik menggunakan uji Fischer mendapatkan p value = 0,006 ( p < 0,05) yang menunjukkan ada hubungan yang bermakna antara riwayat malaria sebelumnya dengan kejadian malaria melalui hapusan darah transfusi pendonor. Kata-kata kunci: riwayat malaria, kejadian malaria, donor darah
Pola Resistensi Bakteri Kontaminan Luka Pasien di Bangsal Bedah Ortopedi RSUD Ulin Banjarmasin Periode Juli-September 2013: Tinjauan In Vitro Pola Resistensi Isolat Bakteri Kontaminan Asal Swab Luka Pasien di Bangsal Bedah Ortopedi RSUD Ulin Banjarmasin Terhadap Gentamisin, Kloramfenikol, Sefotaksim dan Seftriakson Rihansyah, Akbar; Putera, Husna Dharma; Budiarti, Lia Yulia
Berkala Kedokteran Vol 10, No 2 (2014): September 2014
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i12.964

Abstract

ABSTRACT: Surgery, trauma, burns, and other factors can affect the defense/skin barrier against bacterial contamination that can cause infection. The risk of infection must be remained of the rational use of prophylactic antibiotics. Rational use of antibiotic susceptibility test results obtained by antibotic against bacteria. The aim of this research was to figure out the resistance pattern of bacteria contaminant in patient’s wound at Orthopaedic Ward of RSUD Ulin Banjarmasin to selected antibiotics i.e. gentamicin, chloramphenicol, cefotaxime and ceftriaxone from July-September 2013. This was descriptive research. The samples were taken with consecutive sampling technique according to inclusion criteria. This research used wound swab bacteria contaminant isolates i.e. Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, and Streptococcus sp. Antibiotic susceptibility test was done in vitro with Kirby-Bauer diffusion method. The radical zones were measured and compared to CLSI 2011 standard. The antibiotic susceptibility test result showed that Staphylococcus aureus was sensitive to gentamicin (100%) and cefotaxime (66,67%), resistant to chloramphenicol (44,44%); Staphylococcus epidermidis was sensitive to cefotaxime (28,75%), resistant to gentamicin (85,71%) and chloramphenicol (57,14%); Pseudomonas aeruginosa was sensitive to cefotaxime (33,33%), resistant to ceftriaxone (66,67%); Streptococcus sp. was sensitive to cefotaxime (50%), resistant to gentamicin (50%), chloramphenicol (100%) and ceftriaxone (50%). Key words:   Antibiotic susceptibility, wound bacterial contaminant. ABSTRAK: Tindakan operasi, trauma, luka bakar dan beberapa faktor lain dapat mempengaruhi pertahanan/barier kulit terhadap kontaminasi bakteri yang dapat menyebabkan infeksi. Risiko terjadinya infeksi harus tetap diwaspadai dengan penggunaan antibiotik profilaksis yang rasional. Penggunaan antibiotik rasional didapatkan berdasarkan hasil uji kepekaan antibotik terhadap bakteri penyebab. Penelitian ini bertujuan untuk mengetahui pola resistensi bakteri kontaminan pada luka pasien di Bangsal Bedah Ortopedi RSUD Ulin Banjarmasin terhadap beberapa antibiotik yaitu gentamisin, kloramfenikol, sefotaksim dan seftriakson periode Juli-September 2013. Penelitian ini bersifat deskriptif. Pengambilan sampel menggunakan teknik consecutive sampling menurut kriteria inklusi. Penelitian ini menggunakan isolat bakteri kontaminan hasil swab luka pasien yaitu Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, dan Streptococcus sp. Uji kepekaan keempat jenis bakteri tersebut dilakukan secara in vitro dengan metode difusi Kirby-Bauer. Zona radikal yang terbentuk diukur dan dibandingkan dengan standar CLSI 2011. Hasil uji kepekaan antibiotika menunjukkan bahwa Staphylococcus aureus sensitif terhadap gentamisin (100%) dan sefotaksim (66,67%), resisten terhadap kloramfenikol (44,44%); Staphylococcus epidermidis sensitif terhadap sefotaksim (28,75%), resisten terhadap gentamisin (85,71%) dan kloramfenikol (57,14%); Pseudomonas aeruginosa sensitif terhadap sefotaksim (33,33%), resisten terhadap seftriakson (66,67%); Streptococcus sp. sensitif terhadap sefotaksim (50%), resisten terhadap gentamisin (50%), kloramfenikol (100%) dan seftriakson (50%). Kata-kata kunci : Kepekaan antibiotika, bakteri kontaminan luka.
Perbandingan Efektivitas Antibakteri antara Ekstrak Metanol Kulit Batang Kasturi dengan Ampisilin terhadap Staphylococcus aureusin Vitro Akbar, M. Rizki Valian; Budiarti, Lia Yulia; Edyson, Edyson
Berkala Kedokteran Vol 12, No 1 (2016): Februari 2016
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v12i1.350

Abstract

Abstract:Kasturi as a typical plant in South Kalimantan is one fruit that has many benefits. The barks of kasturi has proved to have benefits, especially to inhibit the activity of Staphylococcus aureus. Staphylococcus aureus is a gram positive bacteria that cause pneumonia, mastitis, and urinary tract infections. The bark of kasturi can be used in extract form. The objective of this research is to know the difference between the preparations of inhibition kasturi’s bark extract and ampicillin 30μg in inhibiting the growth of Staphylococcus aureus in vitro. This study used an experimental method consisting of 9 treatments with 3 repetitions. Treatment test in the methanol extract of the bark of kasturi 25%, 37.5%, 50%, 62.5%, 75%, 87.5% and 100%. The control group used ampicillin and 70% methanol. Bacterial test was done by using a diffusion method. The parameter measured was the amount of inhibition zone (mm) which grown on media MH. Analysis of study data used One way Annova test and Post Hoc LSD test at α=0,05. The results showed that there were significant differences between the treatment kasturi’s bark extract 25%, 50%, 62.5%, 75%, 87.5% and 100% concentration different compared to ampicillin. Meanwhile, at the concentration of 37.5% (p <0.05) was not significant. The antibacterial effectiveness was obtained from the concentration of 100%. Key words: the bark of kasturi, methanol extract, Staphylococcus aureus, inhibition zone. Abstrak: Kasturi sebagai salah satu tanaman khas yang ada di Kalimantan Selatan merupakan salah satu buah yang memiliki banyak khasiat. Kulit batang kasturi terbukti memiliki manfaat terutama dapat menghambat aktivitas Staphylococcus aureus. Staphylococcus aureus merupakan bakteri gram positif yang menyebabkan penyakit pneumonia, mastitis, dan infeksi saluran kemih. Kulit batang kasturi dapat digunakan dalam bentuk ekstrak. Tujuan penelitian ini mengetahui perbedaan daya hambat antara sediaan ekstrak kulit batang kasturi dengan ampisilin 30µg dalam menghambat pertumbuhan bakteri Staphylococcus aureus secara in vitro. Penelitian ini menggunakan metode eksperimental yang terdiri dari 9 perlakuan dengan 3 kali pengulangan. Perlakuan yang di uji adalah ekstrak metanol kulit batang kasturi 25%, 37,5%, 50%, 62,5%, 75%, 87,5% dan 100%. Dan kontrol perlakuan dengan ampisilin dan metanol 70%. Uji bakteri dilakukan menggunakan metode difusi. Parameter yang diukur adalah besaran zona hambat (mm) yang tumbuh pada media MH. Analisis data penelitian mengunakan uji One way ANNOVA dan uji Post Hoc LSD pada α=0,05. Hasil penelitian menunjukan bahwa terdapat perbedaan bermakna diantara perlakuan ekstrak kulit batang kasturi 25%, 50%, 62,5%, 75%, 87,5% dan 100% konsentrasi yang beda di bandingkan dengan ampisilin. Sedangkan pada konsentrasi 37,5% (p<0,05) tidak bermakna. Efektivitas antibakteri yang terbesar di peroleh dari konsentrasi 100%.Kata-kata kunci: kulit batang kasturi, ekstrak metanol, Staphylococcus aureus, zona hambat.
Hubungan Antara Perilaku Merokok Dan Kejadian Insomnia: Pada Mahasiswa Fakultas Kedokteran Universitas Lambung Mangkurat Mushoffa, Muhammad Annahri; Husein, Achyar Nawi; Bakhriansyah, Mohammad
Jurnal Berkala Kedokteran Vol 9, No 1 (2013): April 2013
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v9i1.921

Abstract

ABSTRACT: Cigarettes contain about 4000 toxic substances thataffecting health status and cigarettes consumption leads to some diseases such as cardiovascular and respiratory diseases, malignancy, mental and other disorders, including insomnia. This researchwas aimed to analyze the association between smoking behavior and insomnia on Medical Faculty student of LambungMangkurat University. It was an observational analytic studywith cross-sectional approach. The population was108 male students who met the inclusion criteria. Insomnia was assessed by Insomnia Rating Scale questionnaire. The result showed that 5 smoker students with insomnia (15.15%), 28 smokers students without insomnia (84.85%), 2 non-smoker students with insomnia (2.67%), and 73 non-smoker students without insomnia (97.33%). The data were analyzed by usingFisher’s statistic test with 95% confidence interval.Statistical analysis revealed that the p value 0.027. Hence, there was anassociation between smoking behavior and insomnia. It couldbe concluded that there wasan significant association betweensmoking behavior and insomnia on Medical Faculty student of LambungMangkurat University.Keywords: smoking behavior, insomnia, male, Medical Faculty student of LambungMangkurat University.ABSTRAK: Rokok memiliki sekitar 4000 zat beracun yang dapat mempengaruhi kesehatan manusia. Berbagai gangguan seperti penyakit kardiovaskular, pernapasan, keganasan, mental dan gangguan lainnya, termasuk insomnia dapat muncul sebagai akibat konsumsi rokok. Penelitian ini bertujuan untuk mengetahui hubungan antara perilaku merokok dan kejadian insomnia pada mahasiswa FK UNLAM. Penelitian ini adalah penelitian observasional analitik dengan pendekatan cross-sectional. Populasi penelitian adalah 108 mahasiswa laki-laki di FK UNLAM yang memenuhi kriteria inklusi. Kejadian insomnia ditentukan dengan menggunakan kuesioner Insomnia Rating Scale. Dari kuesioner didapatkan data mahasiswa perokok dengan insomnia 5 orang (15,15%), mahasiswa perokok tanpa insomnia 28 orang (84,85%), mahasiswa nonperokok dengan insomnia 2 orang (2,67%), dan mahasiswa nonperokok tanpa insomnia 73 orang (97,33%). Data kemudian dianalisis dengan uji statistik Fisher’s.Hasil  analisis data menggunakan uji Fisher’s dengan tingkat kepercayaan 95% menunjukkan nilai p = 0,027. Berdasarkan penelitian ini dapat disimpulkan bahwa terdapat peningkatan risiko terjadinya insomnia pada mahasiswa perokok FK UNLAM. Kata-kata kunci:perilaku merokok, insomnia, laki-laki, FK UNLAM 
Pengaruh Lama Paparan Kebisingan Menurut Masa Kerja terhadap Nilai Ambang Dengar Pekerja : Studi Observasional di PT PLN (Persero) Sektor Barito PLTD Trisakti Banjarmasin Huldani, Huldani
Berkala Kedokteran Vol 10, No 2 (2014): September 2014
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i12.955

Abstract

Abstract: PT PLN (Persero), Trisakti Banjarmasin diesel Barito sector is an industry that uses diesel power to electric power generation using the machine and work tool that has a loud voice so that it will increase the noise exposure and increase the risk of harm to the workers. To determine the effect of long exposure noise according to the service life of the hearing threshold value workers of PT PLN (Persero) Sector Barito diesel Trisakti Banjarmasin, conducted observational study with a cross sectional study of the population of all workers at PT PLN (Persero) Sector Barito diesel Trisakti Banjarmasin. Determination of the respondents used the quota sampling with 30 responden.Hasil research found that the intensity of the noise in the diesel> 85 dB, there are 3 respondents (10%) increase in NAD and the average rate of loss in the case of the respondents is hearing loss in long service life (> 5 years) of 3 respondents (20%) and normal hearing as many as 12 respondents (80%) of the 15 respondents, while the new work (≤ 5 years) as many as 15 respondents (100%) of the 15 respondents. Mann-Whitney U analysis with a level of 95% between the long exposure noise according to the working lives of the employees hearing threshold value p value = 0.07 (p> 0.05). It can be concluded that there is no difference in the increase in NAD workers of PT PLN (Persero) diesel Barito Sector, Trisakti Banjarmasin on years of ≤ 5 years and> 5 years. Key words: noise, period of employment, the value of hearing threshold.  Abstrak: PT PLN (Persero) Sektor Barito PLTD Trisakti Banjarmasin merupakan industri yang menggunakan tenaga diesel untuk pembangkit tenaga listrik dengan menggunakan mesin dan alat kerja yang mempunyai suara keras sehingga akan meningkatkan pemaparan kebisingan serta menambah risiko bahaya pada pekerja. Untuk mengetahui pengaruh lama paparan kebisingan menurut masa kerja terhadap nilai ambang dengar pekerja PT PLN (Persero) Sektor Barito PLTD Trisakti Banjarmasin, dilakukan penelitian observasional analitik dengan studi pendekatan cross sectional dengan populasi seluruh pekerja di PT PLN (Persero) Sektor Barito PLTD Trisakti Banjarmasin. Penentuan responden digunakan dengan quota sampling dengan jumlah 30 responden.Hasil penelitian didapatkan bahwa intensitas kebisingan di PLTD > 85 dB, terdapat 3 responden (10%) peningkatan NAD dan rata-rata tingkat pendengaran pada responden adalah terjadi gangguan pendengaran pada masa kerja lama (> 5 tahun) sebanyak 3 responden (20%) dan pendengaran normal sebanyak 12 responden (80%) dari 15 responden sedangkan masa kerja baru (≤ 5 tahun) sebanyak 15 responden (100%) dari 15 responden. Analisis U-mann whitney dengan taraf kepercayaan 95% antara lama paparan kebisingan menurut masa kerja terhadap nilai ambang dengar pekerja didapatkan nilai p= 0,07 (p > 0,05). Dapat disimpulkan bahwa tidak ada perbedaan peningkatan NAD pekerja PT PLN (Persero) Sektor Barito PLTD Trisakti Banjarmasin pada masa kerja ≤ 5 tahun dan > 5 tahun. Kata-kata kunci: kebisingan, masa kerja, nilai ambang dengar.
PERBEDAAN KAPASITAS FUNGSI PARU PEKERJA TAMBANG BATUBARA ANTARA SHIFT SIANG DAN MALAM Kalistra, Nadia Bunga; Sholihah, Qomariyatus; Hidayah, Nurul
Jurnal Berkala Kedokteran Vol 11, No 1 (2015): Februari 2015
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i1.186

Abstract

The capacity of lung function (FEV1%) is the volume of air expelled in the first second. Impairment of lung function capacity coal miners can be caused by shift work. The study aimed to determine the difference in lung function capacity of coal miners between day shift and night shift. Research method used analytic observational cross-sectional approach. The sample was selected using purposive sampling technique based on the criteria of the Gay and Diehl. A total of 60 samples based on inclusion criteria consisted of 30 people day shift and 30 people night shift. Samples were asked to fill out a questionnaire and pulmonary function tests by means of spirometry BLT-08. Results showed that the capacity of normal lung function 15 (50%) of workers and abnormal lung function capacity 15 (50%) of coal miners afternoon shift. The capacity of normal lung function 6 (20%) of workers and abnormal lung function capacity 24 (80%) of coal miners night shift. Data were analyzed by Chi-square test with p = 0.015 (p <0.05) showed that there was difference in lung function capacity of coal miners between day shift and night shift at PT. Hasnur Riung Synergy Rantau Period July 2014. Keywords: lung function capacity, work shift, day shift, night shift, coal miner
Pemeriksaan Laboratorium Penyakit Hati Rosida, Azma
Berkala Kedokteran Vol 12, No 1 (2016): Februari 2016
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v12i1.364

Abstract

Abstract: Liver as the largest glandular organ which has an important role in glucose and lipid metabolism which helps digestion, absorption of fats and fat-soluble vitamins, as well as the detoxification of the body against toxic substances. Laboratory tests often required liver disease clinician for screening and detecting of abnormalities or liver disease, to help maintaining diagnosis, to estimate the severity of the disease, to help find the etiology of a disease, assess the results of treatment, and also to help direct further diagnostic efforts and assessing the prognosis of liver disease and organ dysfunction. Interpretation of the results of liver function tests was not able to use only one parameter but also used a combination of the results examination, because the integrity of the liver cells was also influenced by factors extra hepatic. In this article discussed some liver function test is divided into three big that liver function tests, measurement of enzyme activity, and a test to look for the etiology of liver disease.Keywords: laboratory, liver disease, liver function tests Abstrak: Hati sebagai organ kelenjar terbesar memiliki peran penting dalam metabolisme glukosa dan lipid, membantu proses pencernaan, absorbsi lemak dan vitamin yang larut dalam lemak, serta detoksifikasi tubuh terhadap zat toksik.  Pemeriksaan laboratorium penyakit hati sering diminta klinisi untuk penapisan dan deteksi adanya kelainan atau penyakit hati, membantu menengakkan diagnosis, memperkirakan beratnya penyakit, membantu mencari etiologi suatu penyakit, menilai hasil pengobatan, membantu mengarahkan upaya diagnostik selanjutnya serta menilai prognosis penyakit dan disfungsi organ hati.  Interpretasi hasil pemeriksaan uji fungsi hati tidak dapat menggunakan hanya satu parameter tetapi menggunakan gabungan beberapa hasil pemeriksaan, karena keutuhan sel hati juga dipengaruhi faktor ekstrahepatik. Pada artikel ini dibahas  beberapa uji fungsi hati yang dibagi menjadi 3 besar yaitu uji fungsi hati, pengukuran aktivitas enzim, dan uji untuk mencari etiologi penyakit hati. Kata-kata kunci :laboratorium, penyakit hati, uji fungsi hati
Perbedaan Kadar Kalsium Femur Tikus Setelah Paparan Akut Dan Subkronik Debu Batubara Nurmalita, Karina Solikha; Noor, Zairin; Setiawan, Bambang
Jurnal Berkala Kedokteran Vol 9, No 2 (2013): September 2013
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v9i2.946

Abstract

Abstract: Coal dust is a byproduct of coal processing and pollutants in coal mining area and transportation as well. After inhalation of coal dust, the particles will settle in alveoli of the lungs and spread through the vascular system by inflammatory process. The particles contain various minerals that increased substitution or incorporation process of bone mineral in hydroxyapatite lattice, include calcium. The aimed of this research was to determine the difference of Ca2+ levels in femur wistar rats caused by acute and subchronic coal dust exposure. This research was an observational analytic research. Subjects were male wistar rat bone samples taken from Bank Jaringan PEROSI Banjarmasin. Research subjects divided into seven groups: control, acute exposure (14 days) and subchronic exposure (28 days) each with an exposure dose at 6.25 mg/m3, 12.5 mg/m3, and 25 mg/m3. There were four samples femur in each group. Data were analyzed using Kruskal-Wallis test. The result did not show any significant differences of calcium levels in femoral bone wistar rats after acute (p=0,739) and subchronic exposure (p= 0,123). The conclusion, there were no significant differences of calcium levels in femur rats after exposure to coal dust with various dosage. Keywords: Calcium levels, coal dust, wistar rats, acute, subchronic. ABSTRAK: Debu batubara merupakan produk samping pengolahan batubara sekaligus polutan di area pertambangan dan transportasi batubara. Partikel tersebut mengandung berbagai macam mineral yang dapat memicu proses substitusi atau inkorporasi mineral tulang dalam kristal hidroksiapatit, salah satunya mineral kalsium. Penelitian bertujuan untuk mengetahui perbedaan kadar Ca2+ femur tikus wistar jantan akibat paparan debu batubara yang diberikan pada wakru berbeda. Penelitian ini merupakan penelitian observasional analitik menggunakan sampel tulang tikus wistar jantan yang diambil dari Bank Jaringan PEROSI Banjarmasin. Subjek penelitian dibagi dalam tujuh kelompok yaitu, kontrol, BB1 = dosis batubara 6,25 mg/m3, BB2 = dosis batubara 12,5 mg/m3, dan BB3 = dosis batubara 25 mg/m3, yang masing-masing diberi paparan akut (14 hari) dan paparan subkronik (28 hari). Berdasarkan hasil uji Kruskal-Wallis, disimpulkan bahwa tidak terdapat perbedaan bermakna apabila didapatkan nilai p<0,05. Hasil penelitian menunjukkan perbedaan kadar kalsium tulang femur tikus wistar jantan yang tidak bermakna setelah paparan akut (p=0,739) dan subkronik (p= 0,123). Tidak terdapat perbedaan bermakna dari kadar kalsium femur tikus setelah paparan debu batubara. Kata-kata kunci: Kadar kalsium, debu batubara, tikus wistar, akut, subkronik.
GAMBARAN FAKTOR RISIKO PASIEN KANKER KOLOREKTAL DI RSUD ULIN BANJARMASIN PERIODE APRIL-SEPTEMBER 2014 Rahdi, Dhia Raihana; Wibowo, Agung Ary; Rosida, Lena
Berkala Kedokteran Vol 11, No 2 (2015): September 2015
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i2.172

Abstract

The incidences of colorectal cancer in a developing country such as Indonesia are thought to increase, related to some risk factors that increase the likelihood of colorectal cancer to develop. We have done a study aimed to describe the incidence of colorectal cancer based on risk factor in patients of RSUD Ulin Banjarmasin from April-September 2014. This is a descriptive study using primary data obtained through the use of questionnaire. A total of 39 samples were chosen using non randomized accidental sampling technique. The age group with the most incidence of colorectal cancer was the productive age group (15-64 years old) with as many as 79,49% of all samples. Colorectal cancer patients with a bad diet pattern were as many as 82,05% of all samples. Most of the colorectal cancer patients were diagnosed with colorectal tumor or polyp (69,72%). A total of 30 patients (76,92%) were never diagnosed with ulcerative colitis. As many as 76,93% patients were without any familial history of cancer. The lifestyles of 61,54% colorectal cancer patients were bad lifestyle. Based on the result it can be concluded that diet pattern, age, tumor history, and lifestyle had a significant distribution on the incidences of colorectal cancer. Keywords: colorectal cancer, colorectal polyp, ulcerative colitis.

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