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Berkala Kedokteran
Published by Universitas Lambung Mangkurat
ISSN : 14120550     EISSN : 25485660     DOI : http://dx.doi.org/10.20527
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Berkala Kedokteran is a journal contains scientific articles from original research and literature review in medical and health scope. It is published twice in a year, on February and September.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 478 Documents
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Perbedaan Kadar Advanced Oxidation Protein Products (AOPP) Ovarium Tikus Putih (Rattus norvegicus) yang Terpajan Kadmium dan Tidak Terpajan Kadmium Rahmadhani, Endah Ayu; Suhartono, Eko; Noor, Meitria Syahadatina
Jurnal Berkala Kedokteran Vol 10, No 1 (2014): Februari 2014
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i1.935

Abstract

Abstract: Cadmium ( Cd) is one of hazardous and  poisonous material, which is that every material because of the nature of concentration or amount either directly or indirectly, can pollute the environment, health, the life of human beings and other living creatures. Cadmium induces toxicity or giving rise to a toxic effect through its ability in the formation of various free radical. An increase of free radicals that excessive will trigger oxidative stress. Advanced Oxidation Protein Products (AOPP) is one of the makers of the occurrence of oxidative stress, derived from the influence of oxidative, stress carbonyl, and increasing the activity of inflammatory globally. This research is an experimental laboratoric the study was performed with 2 groups the treatment, first is  the control group P(0) that does not given exposure cd have been given 2 mL/day aquadest for 4 weeks, and the group exposure P(1), who is given exposure of  Cd with concentration  6 mg Cd/L given 2 mL/day for 4 weeks. The results showed average levels of AOPP in the control group P (0) was 5,319 ± 2,540 µM and  exposure group P(1) has an average of 9,360 ± 1,727 µM AOPP levels. Statistical analysis of the results of the Mann-Whitney shows that there is a meaningful difference between a group with a value of p = 0.000. Can be concluded there that effect of the difference of the formation a both group of AOPP, which in AOPP levels  exposure is higher than the control group. Keywords: cadmium, ovarium, Advanced Oxidation Protein Products, oxidative stress.  Abstract: Kadmium (Cd) merupakan salah satu bahan berbahaya dan beracun yaitu setiap bahan yang karena sifat, konsentrasi atau jumlah, baik secara langsung maupun tidak langsung, dapat mencemari lingkungan hidup, kesehatan, kelangsungan hidup manusia serta mahluk hidup lain. Kadmium menginduksi toksisitas atau menimbulkan efek toksik melalui kemampuannya dalam pembentukan berbagai radikal bebas. Peningkatan radikal bebas yang berlebihan akan memicu terjadinya stres oksidatif. Advanced Oxidation Protein Products (AOPP) merupakan salah satu tanda-tanda terjadinya stres oksidatif, yang berasal dari pengaruh oksidatif, stres karbonil, dan peningkatkan aktivitas inflamasi secara global. Penelitian ini bersifat studi eksperimental laboratorik yang dilakukan dengan 2 kelompok perlakuan, yaitu kelompok kontrol P(0) yang tidak diberi pajanan Cd hanya diberi akuadest sebanyak 2 mL/hari selama 4 minggu dan kelompok pajanan P(1) yang diberi pajanan Cd dengan konsentrasi 6 mg Cd/L yang diberikan sebanyak 2 mL/hari selama 4 minggu. Hasil penelitian menunjukkan rerata kadar AOPP pada kelompok kontrol P(0) adalah 5,319 ± 2,540 µM dan kelompok pajanan P(1) memiliki rerata kadar AOPP sebesar 9,360 ± 1,727 µM. Hasil analisis statistik Mann-Whitney menunjukkan bahwa terdapat perbedaan yang bermakna antara kelompok dengan nilai p = 0,000. Dapat disimpulkan terdapat pengaruh perbedaan pembentukan AOPP terhadap kedua kelompok, dimana kadar AOPP pada kelompok pajanan lebih tinggi dibanding kelompok kontrol. Kata-kata kunci: kadmium, ovarium, Advanced Oxidation Protein Products, stres oksidatif.
Imunitas Selular – Netrofil Huldani, Huldani
Berkala Kedokteran Vol 10, No 2 (2014): September 2014
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i12.969

Abstract

Abstract: Neutrophils play a role in nonspecific cellular immune system which can be found in circulation. Neutrophils are white blood cells (leukocytes) are characterized histologically by its ability to stained by the dye neutral and functional with its role in mediating the immune response against infectious microorganisms. . Neutrophil granules are usually pink or purple - blue with dye. Neutrophil Approximately 50 to 80 percent of all white blood cells in the human body. Neutrophils are quite uniform in size with a diameter between 12 and 15 micrometers. The core consists of 2-5 lobes joined together by the hairlike filaments. Neutrophils move by amoeboid movement. In neutrophils migrate to the area of the body to infection or tissue injury. Tensile strength which determines the direction in which neutrophils will move known as chemotaxis and is associated with substance released from the damaged tissue. Neutrophils are active phagocytes that engulf bacteria and other microorganisms and microscopic particles. The granules of neutrophils is a powerful enzyme that can digest various types of cellular material. During the inflammatory response, chemotactic factors of different origin and proinflammatory cytokine signals attracting neutrophils to the site of infection and / or injury. Injured area will issue a neutrophil chemo attractant attractive to the injured area, followed by the formation of reactive oxygen species (ROS) which is used as the bodys defenses. Neutrophils also synthesize and secrete small amounts of several cytokines including IL-1, IL-6, IL-8, TNF-α, and GM-CSF. Keywords: Cellular Immunity - Neutrophils - Chemo attractant Abstrak: Netrofil  berperan dalam sistem imun nonspesifik selular yang dapat ditemukan dalam sirkulasi. Neutrofil adalah sel darah putih ( leukosit ) yang ditandai secara histologi oleh kemampuannya untuk ternoda oleh pewarna netral dan fungsional dengan perannya dalam mediasi respon imun terhadap mikroorganisme menular. . Granul neutrofil biasanya berwarna merah muda atau ungu - biru dengan zat pewarna . Netrofil Sekitar 50 sampai 80 persen dari semua sel darah putih dalam tubuh manusia. Neutrofil cukup seragam dalam ukuran dengan diameter antara 12 dan 15 mikrometer . Inti terdiri dari 2-5 lobus bergabung bersama oleh filamen mirip rambut . Neutrofil bergerak dengan gerakan amoeboid. Dalam tubuh neutrofil bermigrasi ke daerah infeksi atau cedera jaringan . Kekuatan tarik yang menentukan arah di mana neutrofil akan bergerak dikenal sebagai kemotaksis dan berhubungan dengan zat yang dilepaskan dari tempat kerusakan jaringan. Neutrofil adalah fagosit aktif yang dapat menelan bakteri dan mikroorganisme lain dan partikel mikroskopis . Granul neutrofil merupakan  enzim kuat yang mampu mencerna berbagai jenis bahan selular. Selama respon inflamasi, faktor chemotactic asal yang berbeda dan sinyal sitokin proinflamasi menarik neutrofil ke tempat infeksi dan / atau cedera. Daerah yang mengalami cedera akan mengeluarkan chemo attractant yang menarik neutrofil ke daerah cedera tersebut, diikuti pembentukan reactive oxygen species (ROS) yang digunakan sebagai pertahanan tubuh. Neutrofil juga mensintesis dan mensekresi sejumlah kecil beberapa sitokin termasuk IL-1, IL-6, IL-8, TNF-α, dan GM-CSF. Kata-kata Kunci : Imunitas Selular – Netrofil – Chemo attractant
KADAR TESTOSTERON INTRATESTIKULAR TIKUS Rattus novergicus STRAIN Sprague dawley AKIBAT PEMBERIAN KURKUMIN SETELAH STIMULASI hCG Khatimah, Husnul
Berkala Kedokteran Vol 11, No 2 (2015): September 2015
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i2.168

Abstract

Curcumin is an active agent on Curcuma longa. Curcumin had so many biologic activities; one of them is anti fertility. Curcumin research in male reproductive system had been done. Curcumin reduced testis weight and serum testosterone. This study is done to know curcumin effect on testosterone intratesticular level in rats. This study was conducted to 15 male Sprague dawley rats aged 90 days. Rats divided into 5 groups treatment : group 1 rats were given aquades, group 2 rats were given a single dose of 50 IU hCG, group 3 rats were given CMC, group 4 rats were given curcumin, group 5 rats were given hCG and curcumin.  Rats were sacrified on age 91 days. Testis was taken, homogenizer and sentrifuge. Supernatant was taken in order to measured intratesticular testosterone level. The result of this study show intratesticular testosterone level from 5 group treatment, each group are n = 3, are (1) 44.36±1.30 (aquades), (2) 41.53±16.44 (hCG), (3) 37.33±9.05 (CMC), (4) 54.16±29.82 (curcumin), (5) 49.36±5.05 (hCG + curcuminStatistic analytic with ANOVA showed there is no significant difference  (p>0.05). This study had a conclusion that curcumin not decreased testosterone intratestikular level in rats. Keywords: curcumin, hCG, intratesticular testosterone
Pengaruh Insuflasi terhadap Jumlah Sel Mast Peritoneum Tikus Fathoni, Muhammad Halim; Noor, Zairin; Poerwosusanto, Hery
Berkala Kedokteran Vol 12, No 1 (2016): Februari 2016
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v12i1.355

Abstract

Abstract:Peritoneal insufflation is swelling process to perform laparoscopic surgery, the choice of gas for insufflation in laparoscopic surgery, namely CO2. because it is not flammable bleak N2O, so it can be used safely for diathermy in mice. This study aims to determine whether there is influence insufflation in an increased number of mast cells in rats (Rattus norvegicus). This study is pure experimental research with posttest-only control group design, which consists of the control and treatment of pressure 8 mmHg and 10 mmHg, with the results obtained p0 control = 0.52 p1 8 mmHg = 7.84  p2 10 mmHg = 11.94. ANOVA test showed that the increase in the number of mast cells was significantly occurred in the group with a pressure of 10 mmHg as compared to the pressure of 8 mmHg. Based on research carried out can be concluded that the higher the CO2 gas in the insufflation pressure significantly increases the number of mast cells.Keywords: insuflation, peritoneal, cell Mast Abstrak: Insuflasi adalah proses penggembugan peritoneum untuk melakukan pembedahan laparoskopi, pilihan gas untuk insuflasi pada bedah laparoskopi yaitu CO2. karena tidak mudah terbakar seprti N2O, sehingga dapat digunakan secara aman untuk diatermi pada tikus. Penelitian ini bertujuan untuk mengetahui apakah ada pengaruh insuflasi dalam peningkatan jumlah sel mast pada tikus putih (Rattus norvegicus). penelitian ini merupakan penelitian experimental murni dengan posttest-only with control group design, yang terdiri dari kontrol dan perlakuan dengan tekanan 8 mmHg dan 10 mmHg, dengan hasil yang didapatkan p0 kontrol = 0,52 p1 8 mmHg = 7,84 p2 10 mmHg=11,94. Uji anova menunjukan bahwa peningkatan jumlah sel mast secara bermakna terjadi pada kelompok dengan tekanan 10 mmHg dibandingkan dengan tekanan 8 mmHg. Berdasarkan penelitian yang dilakukan dapat diambil kesimpulan bahwa semakin tinggi tekanan gas CO2 pada insuflasi secara bermakna dapat meningkatkan jumlah sel mast. Kata-kata Kunci :Insuflasi, sel mast, peritoneum
Efek Pajanan Kadmium (Cd) terhadap Aktivitas Katalase Darah Tikus Putih (Rattus norvegicus) Khairunanda, Nuryandi; Suhartono, Eko; Triawanti, Triawanti
Jurnal Berkala Kedokteran Vol 10, No 1 (2014): Februari 2014
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i1.926

Abstract

ABSTRACT: Cadmium (Cd) is a heavy metal compound which is often founded in the environment and food. It has a wide variety of negative effects on target exposed organs, such as blood. Cd increases the Reactive Oxygen Species (ROS) which will lead to an increase in catalase (CAT) activity. The aim of this study was to determine the effect of Cd exposure on CAT activity in the rat ovary (Rattus norvegicus). It was an experimental laboratory using 2 groups. Control group P (0) was given 2 mL aquadest and treatment group P (1) was given Cd with 1,2 x 10-2 mg daily for 4 weeks. The results showed that the mean of the activity of CAT in the control group P(0) was 0,382 + 0,225 μU/mg while in the treatment group P(1) was 0,458 + 0,393 μU/mg. The statistical analysis test using unpaired t test showed an insignificant differences between those two groups with p = 0,599 (p > 0,05). It can be concluded that Cd does not have effect on activity of CAT in the rats’ blood. Keywords: cadmium, catalase activity, oxydative stress..ABSTRAK: Kadmium (Cd) adalah suatu senyawa logam berat yang sering terdapat pada lingkungan dan makanan. Cd memiliki berbagai efek negatif pada organ target yang terpajan, salah satunya adalah darah. Mekanisme Cd untuk merusak jaringan yang terpajan adalah dengan meningkatkan Reactive Oxygen Species (ROS) yang akan menyebabkan peningkatan aktivitas katalase (CAT). Penelitian ini bertujuan untuk mengetahui efek pajanan Cd terhadap aktivitas CAT pada darah tikus putih (Rattus norvegicus). Penelitian ini bersifat laboratorik eksperimental yang dilakukan pada 2 kelompok, yakni kelompok kontrol P(0) yang diberi akuadest sebanyak 2 mL dan kelompok pajanan P(1) yang diberi Cd dengan dosis 1,2 x 10-2 mg setiap hari selama 4 minggu. Hasil penelitian didapatkan rerata pada kelompok kontrol P (0) sebesar 0,382 + 0.225 µU/mg dan pada kelompok perlakuan P(1) sebesar 0,458 + 0,393 µU/mg. Pada uji t tidak berpasangan didapatkan tidak ada perbedaan yang bermakna dari kedua kelompok dengan p = 0,037 (p < 0,05). Dapat disimpulkan bahwa Cd tidak memiliki efek pada aktivitas CATpada darah tikus putih. Kata-kata kunci: kadmium, aktivitas katalase, stres oksidatif.
Identifikasi Bakteri Penyebab Infeksi Saluran Kemih pada Pasien Urolithiasis di Ruang Perawatan Bedah RSUD Ulin Banjarmasin Periode Juni-Agustus 2013 Nufaliana, Sri Hayati; Rahman, Eka Yudha; Budiarti, Lia Yulia
Berkala Kedokteran Vol 10, No 2 (2014): September 2014
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i12.960

Abstract

ABSTRACT: Urinary tract stone or urolithiasis is a pathological condition which is presented by the existence of the stone in the urinary tract. The existence of this stone may make the normal imunity of urinary tract decrease, so that the bacteria can enter, stay and grow until make urinary tract infection (UTI). Urinary tract infection is diagnosed by finding cases of positive urine culture (>105cfu/ml). The aim of this research was to figure out the type of bacteria in urolithiasis patients with UTI at surgical treatment room of RSUD Ulin Banjarmasin during June-August 2013. This study was a descriptive research with cross sectional approach. The samples were taken with totally sampling methode who fullfilled  inclusion criteria. There were 19 urolithiasis patients at surgical treatment room of RSUD Ulin Banjarmasin. From urine examination, there were 13 patients with UTI. Bacterial identification showed there were 3 types of bacteria, Escherechia coli (53,84%), Pseudomonas aeruginosa (38,46%), and Proteus sp. (7,69%). Keywords: urinary tract infection, urinary tract infection’s bacteria, urolithiasis ABSTRAK: Batu saluran kemih atau urolithiasis adalah suatu kondisi patologis yang ditandai dengan keberadaan batu di sepanjang traktus urinarius. Kehadiran batu ini dapat membuat pertahanan saluran kemih yang normal berkurang, sehingga bakteri dapat masuk, menetap dan berkembang biak yang akhirnya menimbulkan infeksi saluran kemih (ISK). ISK dapat didiagnosis jika ditemukan koloni bakteri (>105cfu/ml). Penelitian ini bertujuan untuk mengetahui gambaran jenis bakteri penyebab ISK pada pasien urolithiasis di ruang perawatan bedah RSUD Ulin Banjarmasin selama periode Juni-Agustus 2013. Penelitian ini bersifat deskriptif dengan pendekatan cross sectional. Pengambilan sampel menggunakan totally sampling method menurut kriteria inklusi. Sampel pada penelitian ini adalah 19 pasien urolithiasis di ruang perawatan bedah RSUD Ulin Banjarmasin. Hasil pemeriksaan urine dari 19 pasien urolithiasis diperoleh 13 pasien urolithiasis dengan ISK. Hasil identifikasi bakteri pada 13 pasien urolithiasis dengan ISK didapatkan bakteri penyebab ISK pada pasien urolithiasis yaitu Escherechia coli (53,84%), Pseudomonas aeruginosa (38,46%), dan Proteus sp. (7,69%). Kata-kata kunci: bakteri penyebab ISK, infeksi saluran kemih, urolithiasis
PERBEDAAN KADAR KOLESTEROL TOTAL PASIEN PENYAKIT JANTUNG KORONER DENGAN DIABETES MELITUS DAN TIDAK DIABETES MELITUS Sari, Desy Puspita; Pratiwi, Dewi Indah Noviana; Yuliana, Ida
Jurnal Berkala Kedokteran Vol 11, No 1 (2015): Februari 2015
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i1.191

Abstract

Coronary heart disease (CHD) is the major cause of death  in the world.CHD is constriction or occlusion of arteries which supply blood flow to heart muscle with the result lack of blood oxygen supply because atherosclerosis process or spasm or both. The incidence of atherosclerosis at large artheries increase in diabetes melitus (DM) patients.DM is a major risk factor for CHD pathogenesis. One of risk factor for CHD in DM patients is the  increase of  cholesterol level, a lipid metabolism abnormality.This study aimed to analyze the comparation of total cholesterol between CHD with DM and without DM in RSUD Ulin Banjarmasin period June-August 2014. This study was analytic observational with cross-sectional approach and used consecutive sampling. The total of  sample was 60 patients which contain 30 CHD with DM patients and 30 CHD without DM patients. The result showed the mean of CHD with DM patients’s cholesterol total level was 230,50 mg/dL and the mean of CHD without DM patient’s was 197,47 mg/dL.The data anlysis result using independent T-test showed that there is significant difference of cholesterol total level between CHD with DM patients and CHD witout DM patients (p=0,007) in RSUD Ulin Banjarmasin. Keywords: coronary heart disease (CHD), diabetes melitus (DM), total cholesterol
Gambaran Kejadian Kecemasan Pada Ibu Penderita Retardasi Mental Sindromik Di Slb-C Banjarmasin: Tinjauan Terhadap Usia Anak, Paritas Dan Tingkat Pendidikan Ibu Norhidayah, Norhidayah; Wasilah, Siti; Husein, Achyar Nawi
Jurnal Berkala Kedokteran Vol 9, No 1 (2013): April 2013
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v9i1.917

Abstract

ABSTRACT: Mental retardation is one of the things that can cause anxiety in a mother. There are several factors that influence the anxiety that age, education level, gender and socio-cultural. This research aims to determine the incidence of anxiety in mothers with mental retardation in terms of age, parity and maternal education level. This research uses observational methods. The Results have 59.26% of women who experience anxiety. Mothers who experience anxiety in terms of the childs age was 22.22% in children aged ≤ 12 years and 37.04% at age >12 years. Mothers who experience anxiety in terms of parity was 33.33% of the mothers in the low parity and 25.93% in high parity. Mothers who experience anxiety in terms of education level shows 40.74% at low levels of education, and 18.52% higher educational level. The conclusion of this research is mostly mothers with mental retardation children experience anxiety at  age >12 years, low parity and low education levels. Keywords: anxiety, syndromic mental retardation. ABSTRAK: Retardasi mental merupakan salah satu hal yang dapat menimbulkan kecemasan pada seorang ibu. Ada beberapa faktor yang berpengaruh terhadap kecemasan yaitu usia, tingkat pendidikan, jenis kelamin dan sosial budaya. Penelitian ini bertujuan untuk mengetahui kejadian kecemasan pada ibu penderita retardasi mental ditinjau dari usia anak, paritas dan tingkat pendidikan ibu. Penelitian ini menggunakan metode observasional.. Hasil penelitian menunjukkan 59,26% ibu  penderita retardasi mental mengalami kecemasan. Ibu yang mengalami kecemasan ditinjau dari usia anak adalah 22,22% pada usia anak ≤12 tahun dan 37,04% pada usia anak >12 tahun. Ibu yang mengalami kecemasan ditinjau dari paritas adalah 33,33% ibu pada paritas rendah dan 25,93% paritas tinggi. Ibu yang mengalami kecemasan ditinjau dari tingkat pendidikan menunjukkan 40,74% pada tingkat pendidikan rendah dan 18,52% tingkat pendidikan tinggi. Kesimpulan dari penelitian ini adalah sebagian besar ibu penderita retardasi mental mengalami kecemasan pada usia anak >12 tahun, paritas rendah dan tingkat pendidikan rendah. Kata-kata kunci :kecemasan, retardasi mental sindromik
Hubungan Kadar HbA1C Dengan Kejadian Kaki Diabetik Pada Pasien Diabetes Melitus: Di RSUD Ulin Banjarmasin April-September 2012 Madina, Tria Sefty; Djallalluddin, Djallalluddin; Yasmina, Alfi
Jurnal Berkala Kedokteran Vol 9, No 2 (2013): September 2013
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v9i2.951

Abstract

ABSTRACT: Diabetes mellitus (DM) is a disorder characterized by hyperglycemia and impaired metabolism of carbohydrates, fats, and proteins caused by a deficiency of insulin hormone in relative or absolute terms. HbA1c level test is a test that gives an indication of blood glucose levels averaged over the previous 2-3 months, which gives an assessment of a person’s glucose control. When it is not controlled, there will be a risk of diabetic foot complication. This study was aimed to analyze the relationship between HbA1C level and the incidence of diabetic foot ulcer in diabetic patients in RSUD Ulin Banjarmasin in April-September 2012. This study was an analytic observational survey with a cross-sectional approach. Samples were taken with total sampling method with a total sample of 100 patients. The result showed that diabetic patients with diabetic foot ulcers who had HbA1C level ≥ 7% (poor) were 13 subjects (100%) and there were no one who had HbA1C level < 7% (normal), whereas diabetic patients without diabetic foot ulcers with HbA1C level ≥ 7% were 31 subjects (35.6%) and those who had HbA1C level < 7% were 56 subjects (64.4%). The result of data analysis using Fisher test indicated that there was a significant relationship between HbA1C level and the incidence of diabetic foot ulcer (p = 0.008). It could be concluded that there was a relationship between HbA1C level and the incidence of diabetic foot ulcer in DM patients in RSUD Ulin Banjarmasin in April-September 2012. Keywords: HbA1C, diabetic foot ulcer, diabetes mellitus ABSTRAK: Diabetes melitus (DM) adalah kelainan yang ditandai dengan hiperglikemia dan gangguan metabolisme karbohidrat, lemak, dan protein yang disebabkan oleh kekurangan hormon insulin secara relatif maupun absolut. Pemeriksaan HbA1C merupakan tes yang memberikan indikasi kadar glukosa darah rata-rata selama 2-3 bulan sebelumnya, yang memberikan penilaian tentang pengendalian kadar glukosa seseorang. Apabila kadar glukosa tidak terkontrol, dapat berisiko terjadi komplikasi kaki diabetik. Penelitian ini bertujuan untuk menganalisis hubungan kadar HbA1C dengan kejadian kaki diabetik pada pasien DM di RSUD Ulin Banjarmasin bulan April-September 2012. Penelitian ini adalah penelitian survei observasional analitik dengan pendekatan cross-sectional. Pemilihan sampel menggunakan metode total sampling dengan jumlah sampel sebanyak 100 sampel. Hasil penelitian menunjukkan bahwa pasien DM dengan kaki diabetik yang memiliki kadar HbA1C ≥ 7% (buruk) adalah 13 orang (100%) dan tidak ada pasien yang memiliki kadar HbA1C < 7% (normal), sedangkan pasien DM tanpa kaki diabetik yang memiliki kadar HbA1C < 7% sebanyak 31 orang (35,6%) dan yang memiliki kadar HbA1C ≥ 7% adalah 56 orang (64,4%). Hasil analisis data menggunakan uji Fisher menunjukkan bahwa terdapat hubungan bermakna antara kadar HbA1C dengan kejadian kaki diabetik (p = 0,008). Dapat disimpulkan bahwa terdapat hubungan antara kadar HbA1C dengan kejadian kaki diabetik pada pasien DM di RSUD Ulin Banjarmasin bulan April-September 2012. Kata-kata kunci: HbA1C, kaki diabetik, diabetes melitus
HUBUNGAN MINUMAN ISOTONIK DENGAN KONSUMSI OKSIGEN MAKSIMAL PADA MAHASISWA JPOK UNLAM BANJARBARU Azizah, Azizah; Biworo, Agung; Asnawati, Asnawati
Jurnal Berkala Kedokteran Vol 11, No 1 (2015): Februari 2015
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i1.182

Abstract

Maximum oxygen consumption (VO2 max) is the maximum number of individual oxygen that can be used during the exercise and is one of the good measurements of cardiorespiratory fitness. Isotonic drink is one of the drinks that supplies the energy and fluid balance during the exercise.  This research aims to determine whether there is a relationship of isotonic drink with maximum oxygen consumption. This research uses quasi experimental  pretest and posttest design.  The population of this research are the students of JPOK UNLAM Banjarbaru, who were divided into two groups based on before and after giving isotonic drinks. The method of retrieval research subjects is by purposive sampling method, with 33 respondents of the research subjects. The measurement of VO2 max is conducted by using multistage fitness test. The average value of VO2 max before giving isotonic drinks was 45,05 ml/kg/minute and after giving it became 49,34 ml/kg/minute. The paired t test with confidence level 95% showed significant differences in both of the data with the value of p = 0,000, it can be concluded that isotonic drinks can increase VO2 max. Keywords:  isotonic, VO2 max.

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