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Pro-Life
Published by Universitas Kristen Indonesia
ISSN : 23020903     EISSN : 25797557     DOI : 10.33541
Core Subject : Science, Education, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology
Ilmu Biologi merupakan salah satu ilmu yang terus bertumbuh dan menjadi bagian yang penting dalam kehidupan. Ilmu Biologi mencakup kajian teori, penelitian hingga pendidikan Biologi menjadi cakupan ilmiah yang terus diteliti dan dikaji hingga memperoleh manfaat bagi kehidupan. Program studi pendidikan Biologi FKIP-UKI ingin memberikan wadah bagi para peneliti baik di dunia Ilmu Biologi maupun Pendidikan Biologi untuk mempublikasikan hasil kajiannya. Jurnal ini terbentuk pada tahun 2014 dan menjadi referensi bagi para mahasiswa dan peneliti lain dalam melakukan penelitian. Bidang spesifik yang dicakup dalam Jurnal adalah Pendidikan dan Ilmu Biologi. Cakupan/ fokus masalah yang dicakup dalam Jurnal antara lain Pendidikan, Metode Ajar, Tumbuhan, Hewan dan Lingkungan. Jurnal terbit 3 kali dalam satu tahun, yaitu pada Bulan November, Maret dan Juli.
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Articles 8 Documents
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Search results for , issue "Vol. 12 No. 1 (2025): Maret" : 8 Documents clear
Resistensi Treponema pallidum terhadap Makrolida Sebagai Pengobatan Alternatif Sifilis Gultom, Desy Ariani
Pro-Life Vol. 12 No. 1 (2025): Maret
Publisher : Program Studi Pendidikan Biologi Fakultas Keguruan dan Ilmu Pendidikan

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Abstract

Treponema pallidum (T. pallidum) is a pathogen that causes syphilis, which is transmitted through contact with active lesions of a sex partner or an infected pregnant woman to her fetus. Despite various aggressive efforts and pharmacological treatments, syphilis has persisted and continues to be a health problem, even experiencing an increase in the prevalence of the disease in recent years. This article is based on literature studies on various research published online, especially on Google Scholar, ScienceDirect, Scopus, Pubmed, and other scientific journals. The studies were then synthesized into comprehensive information regarding specific resistance mechanisms of T. pallidum bacteria to several antibiotics. Macrolide, especially azithromycin, is an alternative treatment that is most often used in the treatment of syphilis in addition to first-line antibiotics, benzathine penicillin G injection. The use of its single oral dose, its effectiveness equivalent to penicillin, cost-effectiveness, and rare side-effect profile made azithromycin widely used in the treatment of syphilis in various regions throughout the world until treatment failures were reported. The mechanism of resistance to macrolides occurs due to modification of the antibiotic target site (binding site) caused by mutations in the 23S rRNA gene. The increase in cases and the emergence of clinically significant resistance to alternative antibiotics in some countries emphasize the urgent need for vigilance. Knowledge and understanding of the resistance mechanism of Treponema pallidum to antibiotics, especially the macrolides group, is essential in line with the increasing resistance of Treponema pallidum to antibiotics globally.
a JENIS-JENIS TUMBUHAN INVASIF DAN DAMPAKNYA DI HUTAN MUSIM TAMAN NASIONAL BALURAN Salamah, Hatipah; Evi Muliyah; Siti Dela Oktavia; Savira Nuraini; Feby Amelia Anandai; Riska Luthfiah
Pro-Life Vol. 12 No. 1 (2025): Maret
Publisher : Program Studi Pendidikan Biologi Fakultas Keguruan dan Ilmu Pendidikan

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Abstract

Indonesia is rich in biodiversity, with 1.75% of all plants identified worldwide. The biggest threat to biodiversity is invasive plant species. Baluran National Park is a conservation area in Indonesia with various ecosystems and every year; the area experiences increased growth. However, research on invasive plants in one of the Baluran National Park areas, namely the Monsoon Forest, has not been identified. This research aims to identify invasive alien plants and their impacts, which are supported by environmental factors in the Monsoon Forest of Baluran National Park. The method used was direct exploratory research by creating 3 sample plots measuring 10x10 m. The data analysis technique was carried out using quantitative analysis. The research results show that the Monsoon Forest of Baluran National Park has biodiversity in the medium category (H'= 2.808%). Thirty-three species of invasive plants were found, with 1431 individuals. The highest Importance Value Index (IVI) for invasive foreign plants is Digitaria sanguinalis (L.) Scop. 25.4%, Desmanthus virgatus (L.) Willd. and Oplismenus hirtellus (L.) 14.43%, Barleria prionitis L. 12.73%. and the Bidens subalternans, 11.33%.
ANTIOKSIDAN RUMPUT KEBAR (Biophytum umbraculum) Rahmawati, Fri; Bintang, Maria; Yang, Albert Jackson; Talakua, Hazella Ishera
Pro-Life Vol. 12 No. 1 (2025): Maret
Publisher : Program Studi Pendidikan Biologi Fakultas Keguruan dan Ilmu Pendidikan

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Abstract

Oxidative stress is one of the causes of heart disease, atherosclerosis, and cancer. Efforts to overcome oxidative stress include the use of natural antioxidants. Flavonoids and phenolics are secondary metabolite compounds in plants that have antioxidant activity. Plants that are believed to be able to overcome oxidative stress include Kebar grass. Kebar grass (Biophytum umbraculum) is one of the plants that empirically has many benefits including as a female fertility drug by the Kebar-Papua community. The study aimed to determine the antioxidant potential and total phenolic and flavonoid content of Kebar grass extract. Kebar grass extract was obtained through maceration extraction with 96% pro-analysis (p.a) ethanol solvent. Antioxidant testing used the 2.2-diphenyll-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) methods using antioxidant standards, namely ascorbic acid (vitamin C) and gallic acid, while measuring total phenolic and flavonoid levels used the Folin-Ciocalteu and aluminium chloride methods, respectively. The results showed that the total phenolic and flavonoid levels of Kebar grass extract were 52.26 ± 3.94 mg GAE/g dw (dry weight) and 22.15 ± 2.79 mg QE/g dw Kebar grass extract, respectively, while the antioxidants of Kebar grass extract with the DPPH method had an inhibition concentration 50 (IC50) value of 183.44 ppm and a vitamin C standard of 4.46 ppm, and antioxidant testing using the FRAP method obtained a reducing power 50 (RP50) value of Kebar grass extract of 5043.76 ppm with a gallic acid standard value of 101.8 ppm.
Jatropha curcas L. (BOTANI, BIOFUEL, TOKSISITAS, BIOAKTIVITAS) Silalahi, Marina
Pro-Life Vol. 12 No. 1 (2025): Maret
Publisher : Program Studi Pendidikan Biologi Fakultas Keguruan dan Ilmu Pendidikan

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Abstract

This study aims to explain the use (biofuel) and toxicity of  J. curcas. This study is based on an online literature study on Google Scholar using the keywords  J. Curcas and toxicity of  J. curcas. Inedible vegetable oil (biodiesel), such as castor oil, is considered a future raw material because it is a non-edible oil and does not cause food versus fuel conflicts. The potential of  J. curcas as a biofuel is related to the oil content consisting of saturated fatty acids, palmitic acid, stearic acid and unsaturated fatty acids, oleic acid, and linoleic acid. Poisoning due to side effects of  J. curcas seeds occurs in humans, especially children and also in the environment. Symptoms of poisoning caused by  J. curcas can be analyzed through clinical signs, and the effects vary greatly, depending on the concentration, frequency, part eaten and the processing process. Accidentally ingested J. curcas seeds cause clinical syndromes such as restlessness, severe vomiting, and dehydration. Curcacycline A and curcin compound have been successfully identified from  J. curcas with antitumor activity. The potential of  J. curcas as an antitumor needs to be studied further to find alternative treatments for cancer and tumours.
PEMBELAJARAN BIOLOGI BERBANTUAN HANDOUT TERINTEGRASI KOMIK DIGITAL PADA MATERI KESEHATAN REPRODUKSI MANUSIA DI SMA 1 CAWANG BARU Aruan, Destri Natalia; Adinugraha, Fajar; Ratnapuri, Adisti; Setiati, Novi
Pro-Life Vol. 12 No. 1 (2025): Maret
Publisher : Program Studi Pendidikan Biologi Fakultas Keguruan dan Ilmu Pendidikan

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Abstract

Reproductive health education is often challenging and unengaging, particularly for adolescents undergoing puberty. The lack of interactive and entertaining teaching materials further hinders effective learning. This study aims to develop and evaluate a comic-integrated handout on reproductive health for students at SMA 1 Cawang Baru. In this study, the research and development (R&D) approach was employed following Sugiyono's development model. The comic-integrated handout combines material content, comic-based entertainment, educational video links, and online tests. Validation results indicated feasibility scores of 75% (linguist), 78.33% (material expert), and 86.61% (media expert). Students' comprehension in the high category increased from 5.13% to 69.23%, while the low category decreased from 84.61% to 12.82%. Test scores improved from 44.62 to 81.03, with an overall perception score of 84.55% categorized as "Strongly Positive". These findings indicate that the comic-integrated handout is a potential and promising educational tool that improves student engagement and understanding. Therefore, we suggest this approach could be applied in future studies that focus on refining contextual relevance and expanding the approach's implementation across various educational settings.
Faktor Risiko Diabetes Melitus dan Prevalensi Penyakit Jantung Koroner di RSU UKI Tahun 2021-2023 Simanjuntak, Desy Ria; Nugroho, Reynard Alexander
Pro-Life Vol. 12 No. 1 (2025): Maret
Publisher : Program Studi Pendidikan Biologi Fakultas Keguruan dan Ilmu Pendidikan

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Abstract

Coronary heart disease (CHD) remains a major cause of death globally, with its prevalence increasing over time. Diabetes mellitus is recognized as a significant risk factor for CHD. This study aims to explore the relationship between diabetes mellitus and CHD among patients at UKI General Hospital (RSU UKI). Utilizing a cross-sectional, retrospective, and descriptive-analytic design, this research analyzed medical records of CHD patients from January 2021 to December 2023, processed using SPSS software. Results indicated that CHD was most prevalent among individuals aged 60–69, with a higher incidence in men. Unemployment was common among CHD patients, and most had an education level above high school. During the study period, 79 CHD cases were recorded, with 21 patients having a history of diabetes mellitus. Data showed a consistent increase in CHD cases over the three-year period. The study revealed that individuals with diabetes mellitus were 3.5 times more likely to develop CHD. However, despite this finding, the data from RSU UKI indicated a relatively weak association between diabetes mellitus and CHD. These findings suggest that while diabetes mellitus is a notable risk factor for CHD, additional research is necessary to identify other contributing factors in this population.
Karakteristik Morfo-Anatomi serta Kandungan Klorofil dan Kandungan Fitokimia Tanaman Ketul (Bidens pilosa) pada Tempat dengan Intensitas Cahaya yang Berbeda di Arboretum Universitas Padjadjaran Marcelline, Karen; Nurzaman, Mohamad; Setiawati, Tia
Pro-Life Vol. 12 No. 1 (2025): Maret
Publisher : Program Studi Pendidikan Biologi Fakultas Keguruan dan Ilmu Pendidikan

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Abstract

Bidens pilosa is a plant known for its secondary metabolites with therapeutic properties. This study aimed to examine the effects of different light intensities on the morphology, anatomy, chlorophyll content, and secondary metabolite production of B. pilosa in the Arboretum of Universitas Padjadjaran. The shaded and unshaded area had light intensities of 5828 and 32768 lux, respectively. Leaf samples were collected from three different individuals in each area, with three leaves taken per plant. Morphological and anatomical traits such as leaf thickness, leaf area, stomatal density, and chlorophyll content were observed, along with secondary metabolite content. Results showed that plants in the shaded area had thinner leaves (0,19 mm) and lower stomatal density (275,16 cells/mm2) but a larger leaf area (4 cm2) and higher chlorophyll content (29,33 CCI) compared to leaves in the unshaded area, which had thicker leaves (0,213 mm), higher stomatal density (310,83 cells/mm2), a smaller leaf area (2,33 cm2), and lower chlorophyll content (27,27 CCI). Alkaloids, flavonoids, tannins, and saponins were detected in both conditions, with a higher level of alkaloid and tannin in unshaded plants. These findings enhance our understanding of the relationship between light intensity influences plant morphology, photosynthesis, and secondary metabolite production, with potential applications in cultivation and medicinal use.
Perbedaan Struktur Morfologi, Anatomi, dan Fisiologi serta Kandungan Fitokimia Daun Aur-Aur (Commelina diffusa) pada Intensitas Cahaya Berbeda di Embung Leuwi Padjadjaran Handayani, Seviana Esti; Hasan, Rusdi; Mutaqin, Asep Zainal
Pro-Life Vol. 12 No. 1 (2025): Maret
Publisher : Program Studi Pendidikan Biologi Fakultas Keguruan dan Ilmu Pendidikan

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Abstract

Commelina diffusa (family Commelinaceae) contains various secondary metabolites with potential antimicrobial and antioxidant properties. The production of these compounds is influenced by environmental factors, exceptionally light intensity, which also plays a role in determining the plant’s morphological and anatomical characteristics. This study aims to analyze differences in leaf morphology, stomatal anatomical structure, chlorophyll content, and phytochemical compounds in C. diffusa leaves growing in two locations with different light conditions at Embung Leuwi Padjadjaran, Sumedang. A descriptive method was used to examine leaf morphology, stomatal anatomy, chlorophyll content, and phytochemical compounds of C. diffusa in shaded and unshaded locations. The results showed that leaf morphology was relatively similar in both locations, but the leaf surface area was more significant in unshaded conditions (8,33 cm²). The stomata were hexacytic type with higher stomatal density in the shaded condition (591,082 cell/mm²) and a higher chlorophyll content (37,73 CCI). The result of Phytochemical analysis confirmed the presence of alkaloids, flavonoids, saponins, tannins, and quinones, which were relatively higher in unshaded conditions.

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