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MNJ (Malang Neurology Journal)
Published by Universitas Brawijaya
ISSN : 24076724     EISSN : 24425001     DOI : -
Core Subject : Science,
Malang Neurology Journal is a peer-reviewed and open access journal that focuses on promoting neurological sciences generated from basic neurosciences and clinical neurology. This journal publishes original articles, reviews, and also interesting case reports. Brief communications containing short features of medicine, latest developments in diagnostic procedures of neurology disease, treatment, or other health issues related to neurology that is important also acceptable. Letters and commentaries of our published articles are welcome.
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Articles 10 Documents
Search results for , issue "Vol 5, No 2 (2019): July" : 10 Documents clear
PROFILE OF SUBJECTIVE SLEEP DISTURBANCE IN PATIENT WITH ANTIEPILEPTIC DRUGS Zahra, Farah Az; Islamiyah, Wardah Rahmatul; Budiono, Budiono
Malang Neurology Journal Vol 5, No 2 (2019): July
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2019.005.02.2

Abstract

Background: Epilepsy and sleep are well recognized for having bidirectional influences upon one another. The effects of antiepileptic drugs (AEDs) on sleep are of particular concern.
Objective: The objective of this study is to know the profile of AEDs effect in patient’s sleep cycle. Methods: This analytical observational study observed total sleep time, sleep onset latency, sleep efficiency, daytime sleepiness, and insomnia in epileptic patient with AEDs of Neurology Clinic Airlangga University Hospital during May-September 2016. A cross sectional study was done by questionnaire and interview directly to the epileptic patients. Data collected was being analyzed analytically.Results: This research was conducted among 27 patients with epilepsy based on inclusion and exclusion criteria. Sleep disturbances that had been found in patients with phenytoin are prolong sleep onset latency (11.11%), decreased sleep efficiency (11.11%), and excessive daytime sleepiness (66.67%). Sleep disturbances that had been found in patients with valproate are decreased total sleep time (33.33%), prolong sleep onset latency (11.11%), decreased sleep efficiency (11.11%), excessive daytime sleepiness (66.67%), and insomnia (11.11%). Sleep disturbances that had been found in patients with carbamazepine are decreased total sleep time (44.44%), prolong sleep onset latency (33.33%), decreased sleep efficiency (22.22%), excessive daytime sleepiness (77.78%), and insomnia (11.11%).Conclusion: In conclusion, this study shows that epileptic patients who consumed AEDs regularly may have sleep disturbance that vary based on the type of AEDs, patients with carbamazepine may have bigger sleep disturbance than with phenytoin and valproate. It is necessary to give information and education to the epileptic patients who consumed AEDs regularly so that they will become aware of the sign of sleep disturbance.
NEUROPATHIC PAIN IN PATIENT WITH POST OPERATIVE SCHWANNOMA: A CASE REPORT PRIMARY INTRADURAL EXTRAMEDULLAR SPINAL CORD TUMOUR Santoso, Widodo Mardi; Nurlela, Siti; Marhaendraputro, Eko Arisetijono; Rahmawati, Dessika
Malang Neurology Journal Vol 5, No 2 (2019): July
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2019.005.02.7

Abstract

Majority of spinal cord tumour is a benign tumour with symptoms are due to spinal cord compression. One of the symptoms that are often difficult to treat is a sensory deficit. The authors report a case of primary intradural extramedullar spinal cord tumour in 57-year-old man. This tumour was presenting symptoms of chronic low back pain, gradual progressive inferior paraplegia, and sensory deficit on both legs. MRI thoracal showed intradural lesion at Th 4-5-6, with isointensity on T1-weighted images and hyperintensity-isohomogen on T2-weighted images. The tumour was completely resected, and histopathology examination revealed schwannoma types. Patient showed a clinical improvement in motoric function noticeable after surgery, but showed sensory deficits sequelae requiring therapy for neuropathic pain.
EFFICACY OF SHORT TERM VIDEO EEG IN DETECTING PSYCHOGENIC NON-EPILEPTIC SEIZURES Parameswaran, Sajeesh; Vijayamma, Anil Kumar Thankappakurup; Pillai, Ananthanarayana Marthanda
Malang Neurology Journal Vol 5, No 2 (2019): July
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2019.005.02.3

Abstract

Background: Short term video Electroencephalography (SVEEG) is a non-invasive diagnostic procedure typically last for about 1-5 hours. SVEEG can be utilize to differentiate epileptic from Psychogenic Non-epileptic Seizures (PNES).
 Objective: To assess the yield of short term video EEG in detecting PNES.Methods: Retrospective analysis of short term video EEG in a tertiary level hospital. Patient history, provisional diagnosis, previous EEG and imaging reports were tabulated. Various short term video EEG findings like epileptiform abnormalities, PNES and other non-epileptic events were analyzed in detail. According to the provisional diagnosis formed two groups; Suspecting NEE and suspecting seizure disorders. Change in the provisional diagnosis after SVEEGs were also studied.Results: A total of 417 SVEEGs analyzed: 34(8.2%) patients developed events to suggest PNES, 16(3.8%) patients had other non-epileptic events; 96(23%) showed interictal epileptiform discharges,15 (3.6%) showed seizures and 90(21.6%) patients showed non specific EEG abnormalities. Around 60% SVEEGs were conclusive.Conclusion: A diagnostic event was recorded during SVEEG in majority of patients in the PNES group. SVEEG is a cost effective and useful diagnostic procedure; especially to identify non-epileptic events.
NEUROCYSTICERCOSIS IN SOLID ORGAN TRANSPLANTATION PATIENTS Wiwanitkit, Viroj
Malang Neurology Journal Vol 5, No 2 (2019): July
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2019.005.02.8

Abstract

The neurocysticercosis is an important neurological infection. It can be seen in several tropical countries. The neurocysticercosis can affect both healthy people and patients. The organ transplant patient can also get neurocysticercosis. Similar to general case, the neurocysticercosis in organ transplant patients might present with neurological presentation. The practitioner should include neurocysticercosis in differential diagnosis of unexplained neurological episode in any patients with solid organ transplantation.
EVALUATION OF THE CANADIAN CT HEAD RULE FOR ANALYZING DIAGNOSTIC ACCURACY IN PATIENTS WITH MINOR HEAD TRAUMA Kızılgöz, Volkan; Avcı, Sema; Sivrioğlu, Ali Kemal; Aydın, Hasan; Çetin, Türkhun; Kızılgöz, Berihat
Malang Neurology Journal Vol 5, No 2 (2019): July
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2019.005.02.4

Abstract

Background: Head computed tomography (CT) scans, which provide reliable information to assessor rule out neurological abnormalities and injuries, should be used judiciously to minimize radiation exposure and cost. Objective: The aim of this study was to evaluate the widely used Canadian CT Head Rule (CCHR) to determine the necessity of head CT scans in patients with minor head trauma.Methods: This retrospective study included 913 patients with head trauma who were admitted to Harakani State Hospital between June 2014 and December 2017. The patient data were reevaluated according to CCHR and compared with the radiological findings. Results: There were a total of 556 patients fulfilling the inclusion criteria with a male/female ratio of 2.95 and a mean age of 37 ± 4.24 years. The most common injury mechanism of head trauma wasmotor vehicle accidents. Chi square tests were applied for statistical calculations. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of the CCHR were 93%, 88%, 88%, 94%, and 90%, respectively.Conclusion: CCHR was highly useful for patients with minor head trauma who could benefit from head CT evaluation with high sensitivity and specificity.
THE SIDE EFFECTS OF CHEMOTHERAPY IN GLIOMA Raisa, Neila; Marhaendraputro, Eko Arisetijono
Malang Neurology Journal Vol 5, No 2 (2019): July
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2019.005.02.9

Abstract

The increasing number of people who survive in the long term because of the advanced of glioma therapy with chemotherapy causes more slowly emerging neurologic side effects. Currently, there were three medical treatments are approved by the FDA for the management of glioblastoma namely temozolomide, carmustine wafer, and bevacizumab. However, most of the traditional chemotherapy drugs have a target in cell proliferation and cause toxicity of healthy cells. The side effects of chemotherapy on central nervous systems are chemobrain, acute encephalopathy, leukoencephalopathy, cerebellar dysfunction, and spinal cord toxicity. In addition, severe chemotherapy side effects may also occur in the peripheral nervous system called Chemotherapyinduced peripheral neuropathic pain (CIPNP). The clinician should recognize the symptoms of those side effect in glioma patients who received chemotherapy.
THE PREDISPOSING FACTORS OF PIRIFORMIS SYNDROME: STUDY IN A REFERRAL HOSPITAL Siahaan, Yusak Mangara Tua; Ketaren, Retno Jayantri; Hartoyo, Vinson; Tiffani, Pamela
Malang Neurology Journal Vol 5, No 2 (2019): July
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2019.005.02.5

Abstract

Background: Piriformis syndrome is a neuromuscular condition characterized by hip and gluteal pain caused by abnormality of piriformis muscle. In clinical practice, this syndrome is usually misdiagnosed with other spinal disorders. There is no specific test in diagnosing piriformis syndrome, therefore by understanding the characteristics and predisposing factors, clinicians may be more aware in diagnosing this syndrome.
Objective: To investigate the characteristics and predisposing factors of piriformis syndrome.Methods: A descriptive study was conducted on patients with gluteal pain in a referral hospital. Diagnosis was established by block injection on piriformis muscle and showed clinical improvement afterwards. Demographic characteristics, predisposing factors, and physical examination were analyzed. The data is collected and processed by SPSS 20.0.Results: The total of 65 patients were evaluated, with a male to female ratio 1:3. As much as 47.7% of patients were > 60 years old. Average weight was 60 kg and BMI (Body Mass Index) was within normal range (58.9%). Most subjects were housewives (55.4%) and the majority of subjects had history of microtrauma such as sitting on rigid surfaces (36.9%), walking or running long distances (18.5%), and cross-legged sitting (10.8%). Average sitting per day was approximately 5 hours. In 56.9% of subjects, exercises were conducted. There was no history of back pain in 81.5% of subjects.Conclusion: Our study showed age and housewives characteristics differ with other studies. The most predisposing factors were history of microtrauma, female, age, and normal BMI.
CLINICAL APPROACH AND GUIDELINES FOR MANAGEMENT OF SEPSIS ASSOCIATED ENCEPHALOPATHY Trisnawati, Ayu; Munir, Badrul
Malang Neurology Journal Vol 5, No 2 (2019): July
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2019.005.02.10

Abstract

Septic associated encephalopathy (SAE) is simply define as an encephalopathy incidence that occurs in sepsis patients. Ironically this entity can increases the mortality rate. Importantly, the clinical presentations of this entity is vary ranging from malaise to coma condition. The central nervous system is susceptible to damage that caused by systemic inflammation including sepsis with complex pathophysiologies such as endothelial dysfunction, neurotransmitter imbalance, oxidative stress, mitochondrial dysfunction and apoptosis. In general, current management of SAE is similar with the management of sepsis incidence which includes infections management, maintaining tissue perfusion and symptomatic therapy to treat delirium and convulsions that may occur. Also, several studies continue to be developed including the use of corticosteroids, magnesium, antioxidants, and immunoglobulin. Early identification and appropriate initial handling significantly affect the output of the SAE patients.
HISTOLOGICAL ANALYSIS OF WISTAR RATS SCIATIC NERVES SUBJECTED TO COMPRESSION AND TREATED WITH LOW LEVEL LASER THERAPY AND NEURAL MOBILIZATION Antunes, Juliana Sobral; Karvat, Jhenifer; Bernardino, Giovanni Ribeiro; Kakihata, Camila Mayumi Martin; Brancalhão, Rose Meire Costa; Ribeiro, Lucinéia de Fátima Chasko; Aragão, Fernando Amâncio; Bertolini, Gladson Ricardo Flor
Malang Neurology Journal Vol 5, No 2 (2019): July
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2019.005.02.1

Abstract

Background: The physical therapy resources, as Low-Level Laser Therapy (LLLT) and neural mobilization are usually used with regenerative purpose and for the relief of symptoms for peripheral nerve injury. However, there is a lack of consensus on its effects as well as its association. Objective: Evaluate the influence of low-level laser therapy (LLLT) associated with neural mobilization (NM) on nerve regeneration of female Wistar rats subjected to sciatic compression. Methods: Twenty four Wistar rats were divided into: G1 (Placebo), G2 (NM), G3 (LLLT) and G4 (NM+LLLT), all animals were subject to compression of the right sciatic nerve. The treatment occurred on the 3rd, 5th, 7th, 10th, 12th and 14th postoperative day (PO). On the 17th PO the animals were euthanized. Histological and morphometric analysis of the right (compression) and the left (control) sciatic nerve were performed.Results: In the morphometric analysis no significant differences between groups, but differences among sides were found. Histological analysis revealed the presence of inflammatory infiltrate and disruption of nerve fibers in the right sciatic nerves.Conclusion: Both techniques used (LLLT and neural mobilization), isolated and associated, on the parameters proposed, were not effective to accelerate the process of nerve regeneration.
PROFILE OF TYPE 2 DIABETES MELLITUS IN ACUTE THROMBOTIC STROKE Jordan, Danny Randy; Islamiyah, Wardah Rahmatul; Prayitno, Jongky Hendro
Malang Neurology Journal Vol 5, No 2 (2019): July
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2019.005.02.6

Abstract

Background: Stroke is a brain disorder in blood circulation that occur suddenly and last more than 24 hours, which is one leading cause of death in the world. One of the main risk factors of stroke is diabetes mellitus type 2. One complication is that when thrombosis occurs in the brain causing a stroke.Objective: This study aimed to determine the profile of type 2 diabetes mellitus in patients with acute thrombotic stroke who were treated in the Neurology Department at the Hospital Dr. Soetomo.Methods: Sampling was done with purposive sampling by observing the medical records of patients in the period of January 2014 to December 2015 based on inclusion and exclusion criterias that havebeen set.Results: Women with a history of type 2 diabetes are more exposed to acute thrombotic stroke; the age group which is most at risk for stroke is between age of 56-60 years; the average duration of DM until the occurence of stroke is 6,54 ± 4,85 years; more than two-thirds of patients come to the hospital when the acute thrombotic stroke occurs with a condition of hyperglycemia; the most common comorbid disease is hypertension; and insulin therapy is the most widely used therapy in acute thrombotic stroke patients with type 2 diabetes.Conclusion: Managing the risk factors of stroke should prolong or prevent the incident of acute thrombotic stroke since most of the patients with type 2 diabetes mellitus came to the hospital with a condition of hyperglycemia and hypertension.

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