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CORRELATION OF C-REACTIVE PROTEIN LEVELS WITH CLINICAL OUTCOME INTRACEREBRAL HEMORRHAGE STROKE PATIENTS Setianto, Catur Ari; Purnomo, Hari; Marhaendraputro, Eko Arisetijono; Santoso, Widodo Mardi
Malang Neurology Journal Vol 1, No 1 (2015): January
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (578.31 KB) | DOI: 10.21776/ub.mnj.2015.001.01.5

Abstract

Background. Increased levels of markers of inflammatory factors after hemorrhage stroke was able to predict poor clinical outcome. Until now, the role of C Reactive Protein (CRP) in the local inflammatory response and clinical determinants output remains unclear.Objective. To investigate the correlation of CRP level with poor clinical outcome as measured by Barthel Index. Methods. This study was an observasional cohort porspective study performed on haemorrhage stroke patients in Saiful Anwar General Hospital in Februari 2014 until April 2014.Results. There was significant correlation (p=0,01, r=0,613) between CRP levels to poor clinical outcome measured by Barthel Index.Conclusion. C Reactive Protein levels could predict poor clinical outcome as measured by Barthel Index in intracerebral hemorrhage patients.
NEUROPATHIC PAIN IN PATIENT WITH POST OPERATIVE SCHWANNOMA: A CASE REPORT PRIMARY INTRADURAL EXTRAMEDULLAR SPINAL CORD TUMOUR Santoso, Widodo Mardi; Nurlela, Siti; Marhaendraputro, Eko Arisetijono; Rahmawati, Dessika
Malang Neurology Journal Vol 5, No 2 (2019): July
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2019.005.02.7

Abstract

Majority of spinal cord tumour is a benign tumour with symptoms are due to spinal cord compression. One of the symptoms that are often difficult to treat is a sensory deficit. The authors report a case of primary intradural extramedullar spinal cord tumour in 57-year-old man. This tumour was presenting symptoms of chronic low back pain, gradual progressive inferior paraplegia, and sensory deficit on both legs. MRI thoracal showed intradural lesion at Th 4-5-6, with isointensity on T1-weighted images and hyperintensity-isohomogen on T2-weighted images. The tumour was completely resected, and histopathology examination revealed schwannoma types. Patient showed a clinical improvement in motoric function noticeable after surgery, but showed sensory deficits sequelae requiring therapy for neuropathic pain.
COMPARISON OF THE EFFECTIVENESS OF THERAPY IN HYDRODISSECTION INJECTION USING ULTRASONOGRAPHY GUIDENCE BETWEEN NORMAL SALINE AND TRIAMCINOLONE IN CARPAL TUNNEL SYNDROME PATIENTS Santoso, Widodo Mardi; Rakhmatiar, Rodhiyan; Rakhmani, Alidha Nur; Sahidu, Muhammad Ghalvan
Malang Neurology Journal Vol 6, No 1 (2020): January
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2020.006.01.2

Abstract

Background: Carpal tunnel syndrome (CTS) is a peripheral nerve lesion because of the nontraumatic mechanism or a pressure or entrapment of the median nerve under the transverse ligament (flexor retinaculum). Hydrodisection is used for adhesiolysis to eliminate adhesion and release the median nerve from the retinaculum and connective tissue around it and avoid injury to the nerves. Objective: Compare the effectiveness of hydrodisection injection therapy using an ultrasound guide between normal saline and triamcinolone in patients with carpal tunnel syndrome.Methods: Experimental study was carried out in the outpatient clinic of the hospital Dr. Saiful Anwar Malang from August 2018 to October 2018. A total of 30 patients. All study subjects were subjected to NPS, FSS, SSS scoring compared to before and 4 weeks after injection of hydrodisection and compared the effectiveness of injection agents.Results: NPS before and after triamcinolone injection (sig 0.000; p <0.05), FSS (sig 0.020; p <0.05), and SSS (sig 0.001; p <0.05). NPS before and after injection of normal saline 0.9% NaCl  (sig 0.001; p <0.05), FSS (sig 0.005; p <0.05), and SSS (sig 0,000; p <0.05). NPS between triamcinolone injection results and normal saline 0,9% NaCl  (sig 0.341; p <0.05), FSS (sig 0.425; p <0.05), SSS (sig 0.350; p <0.05).Conclusion: There no significant difference between injection of hydrodisection USG guiding with triamcinolone and normal saline 0,9% NaCl to reduce symptom CTS. Both of injection hydrodisection USG guiding has more or less the same effectiveness in treatment of carpal tunnel syndrome.Keywords: CTS, Hydrodisection, NPS, FSS, SSS
NEUROLOGICAL MANIFESTATION ON HOSPITALIZED PATIENT WITH PROBABLE COVID-19 IN SAIFUL ANWAR HOSPITAL INDONESIA (SERIAL CASES) Munir, Badrul; Rianawati, Sri Budhi; Kurniawan, Shahdevi Nandar; Santoso, Widodo Mardi; Arisetijono, Eko; Candradikusuma, Didi; Heri, Sutanto; Chozin, Iin Noor; Dwi, Pratiwi Suryanti; Astuti, Tri Wahju; Asmiragani, Syaifullah
MNJ (Malang Neurology Journal) Vol. 6 No. 2 (2020): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

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Abstract

Background: Coronavirus disease 2019 (Covid-19) caused by SARS-Cov-2 had been spreading worldwide including Indonesia, but In Indonesia, it was difficult to diagnose confirmation Covid-19 by Polymerase Change Reaction (PCR). and in clinical practice to treat covid-19,  Indonesia Health Ministry use term probable covid-19 for patients under observation Covid-19, but study for neurological manifestation on  probable Covid-19 is very lacking.Objective: Knowing the neurological manifestation of patient probable Covid-19.Methods: Observational study from Covid-19 medical record and neuro-Covid-19 medical record of all probable Covid-19 hospitalized in the isolation ward of Saiful Anwar Hospital (RSSA) Malang since March-May, 2020 (3 months). Probable Covid-19 criteria were given by Covid-19 task force team based on Health Minister Indonesia criteria. This criterion was based on clinical manifestation (severe upper respiratory symptoms, or mild-severe pneumonia), radiologic examination (lung infiltrate and or chest CT scan), and laboratory examination. Neurological manifestation is based on clinical symptom appeared while patient hospitalized, supported with radiologic and laboratory data which was supervised by neurologist or neurologist resident. All data was inputted to neuro-Covid-19 e-registry on the smartphone application, sent periodically to the data center in Neurology Department RSSA Malang.Results: A hundred and fourteen probable Covid-19 was registered with mean age 34,5 year old and mostly at the young age of 20-50 years (38%). The neurological manifestation was observed in 4 patients (3,4% from all possible Covid-19 patients) with thrombotic stroke as the most common manifestation (50%), followed by myelum tumor (25%) and hypoxia encephalopathy (25%). Stroke patients in probable Covid-19 had old age (72 and 82 years) accompanied by several comorbid such as hypertension, DM and CVA history and Covid symptoms of cough, shortness of breath and fever. Hemiparesis was found improved with aspirin and neurotropic therapy. Patient with myelum tumor had a covid symptom of shortness of breath, cough, and fever with UMN tetraparesis. Previous MRI examination results suspected meningioma. The patient died while hospitalized. Patients with hypoxia encephalopathy admitted with decreased consciousness due to shortness of breath with acidosis respiratory symptoms (pH 7,22 ). This condition improved after oxygenation without focal neurologic deficit.Conclusion: Neurological manifestation in probable Covid-19 was 3,4% of all patients. The most common diagnosis was a thrombotic stroke, followed by myelum tumor, hypoxia encephalopathy, and mortality rate is 25%.
The effectivity of ultrasound-guided platelet-rich plasma perineural injection in improving leprosy sensory peripheral neuropathy Brahmanti, Herwinda; Widiatmoko, Arif; Widasmara, Dhelya; Sari, Diane Tantia; Kurniawan, Shahdevi Nandar; Santoso, Widodo Mardi; Laksono, Ristiawan Muji; Gofur, Abdul
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 7, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: Sensory nerve damage is the earliest leprosy sign which can lead to disability. Previous studies showed that autologous platelet-rich plasma (PRP) perineural blind injection can stimulate leprosy sensory nerve regeneration. Our study provided a safer and more accurate PRP agent delivery method through ultrasound-guided injection and was the first to compare PRP versus standard neuropathy treatment, the neurotropic vitamin. This study aimed to determine the effectiveness of combination therapy of ultrasound-guided PRP perineural injection and oral vitamin B complex compared to single oral vitamin B complex in sensory peripheral neuropathy of posterior tibial nerve in leprosy patients.
ICU SERVICE FINANCING: WEIGHING REGULATIONS AGAINST PROFESSIONAL JUDGMENT Santoso, Widodo Mardi; Manzilati, Asfi; Ratri, Devita Rahmani; Hariyanti, Tita
Journal of Community Health and Preventive Medicine Vol. 5 No. Issue Supplement 1 (2025): JOCHAPM Vol. 5, Issue Supplement 1, March 2025
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

The Intensive Care Unit (ICU) is one of the most resource-intensive departments in a hospital. Patients admitted to the ICU incur, on average, three times higher costs than those in general wards. However, healthcare professionals, particularly doctors and nurses, often remain unaware of these high costs.   This study employs a qualitative research design using a case study approach. A total of seven participants were selected through purposive sampling. Data were collected through unstructured observations of the ICU environment and unstructured interviews with participants. Thematic analysis was then used to interpret the findings. Four key themes emerged: (1) The ICU as the last hope for survival, (2) Doctors and nurses feeling powerless over treatment costs, (3) The predominant focus of doctors and nurses on medical aspects, and (4) Sentosa Hospital: Between Regulation and Professionalism. The study was conducted at a provincial referral hospital, classified as a type A hospital and a teaching center, where patients present with complex medical conditions. This complexity often leads doctors and nurses to prioritize medical care over financial considerations. In conclusion, ICU doctors and nurses demonstrate limited awareness of the financial burden of patient care. To enhance this awareness, targeted interventions are needed to sensitize all healthcare professionals, particularly doctors and nurses, to the economic aspects of critical care.