Garuda - Garba Rujukan Digital

Article Per Year (5 Year)

All

Dental Journal (Majalah Kedokteran Gigi)

MKG
Website

Published by Universitas Airlangga

ISSN : 19783728 EISSN : 24429740 DOI : -

Core Subject : Health,

Dentistry

The Dental Journal (Majalah Kedokteran Gigi) (e-ISSN:2442-9740; p-ISSN:1978-3728) is published by the Faculty of Dental Medicine, Universitas Airlangga. Its diciplinary focus is dental science and dental hygiene. The Dental Journal (Majalah Kedokteran Gigi) is published in English on a quarterly basis with each 50-60 page edition containing between nine and eleven scientific articles on research, study literature and case studies. Contributors to the Dental Journal (Majalah Kedokteran Gigi) included: dental researchers, dental practitioners, lecturers, and students drawn from Indonesia and a wide range of other countries.

Arjuna Subject : -

Articles 950 Documents

11 12 13 14 15

Cytotoxicity difference of 316L stainless steel and titanium reconstruction plate Ni Putu Mira Sumarta; Coen Pramono Danudiningrat; Ester Arijani Rachmat; Pratiwi Soesilawati
Dental Journal (Majalah Kedokteran Gigi) Vol. 44 No. 1 (2011): March 2011
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: Pure titanium is the most biocompatible material today and used as a gold standard for metallic implants. However, stainless steel is still being used as implants because of its strength, ductility, lower price, corrosion resistant and biocompatibility. Purpose: This study was done to revealed the cytotoxicity difference between reconstruction plate made of 316L stainless steel and of commercially pure (CP) titanium in baby hamster kidney-21 (BHK-21) fibroblast culture through MTT assay. Methods: Eight samples were prepared from reconstruction plates made of stainless steel type 316L grade 2 (Coen’s reconstruction plate®) that had been cut into cylindrical form of 2 mm in diameter and 3 mm long. The other one were made of CP titanium (STEMA Gmbh®)) of 2 mm in diameter and 2,2 mm long; and had been cleaned with silica paper and ultrasonic cleaner, and sterilized in autoclave at 121° C for 20 minutes.9 Both samples were bathed into microplate well containing 50 μl of fibroblast cells with 2 x 105 density in Rosewell Park Memorial Institute-1640 (RPMI-1640) media, spinned at 30 rpm for 5 minutes. Microplate well was incubated for 24 and 48 hours in 37° C. After 24 hours, each well that will be read at 24 hour were added with 50 μl solution containing 5mg/ml MTT reagent in phosphate buffer saline (PBS) solutions, then reincubated for 4 hours in CO2 10% and 37° C. Colorometric assay with MTT was used to evaluate viability of the cells population after 24 hours. Then, each well were added with 50 μl dimethyl sulfoxide (DMSO) and reincubated for 5 minutes in 37° C. the wells were read using Elisa reader in 620 nm wave length. Same steps were done for the wells that will be read in 48 hours. Each data were tabulated and analyzed using independent T-test with significance of 5%. Results: This study showed that the percentage of living fibroblast after exposure to 316L stainless steel reconstruction plate was 61.58% after 24 hours and 62.33% after 48 hours. And after exposure to titanium reconstruction plate, the percentage of living fibroblast was 98.69% after 24 hours and 82.24% after 48 hours. Based on cytotoxicity parameter (CD50%), both reconstruction plate made of 316L stainless steel or titanium showed as a non-toxic materials to fibroblast. Conclusion: Both reconstruction plate made of stainless steel and CP titanium were non-toxic to fibroblast, although the stainless steel plate showed lower cytotoxicity level compared to titanium. Therefore a reconstruction plate made from stainless steel type 316L can be used as a safe material for mandibular reconstruction. Latar belakang: Titanium murni adalah bahan yang paling biokompatibel saat ini dan digunakan sebagai standar emas implan logam. Saat ini stainless steel masih digunakan karena kekuatan, ductility, harganya yang murah, tahan terhadap korosi dan cukup biokompatibel. Tujuan: Penelitian ini dilakukan untuk mengetahui perbedaan sitotoksisitas antara plat rekonstruksi yang terbuat dari titanium murni komersial dan plat rekonstruksi yang terbuat dari stainless steel pada kultur sel fibroblas baby hamster kidney-21 (BHK-21) menggunakan MTT assay. Metode: Delapan sampel yang masing-masing tipe 316L terbuat dari stainless steel 316L grade 2 (Coen’s reconstruction plate®) yang dipotong berbentuk silinder diameter 2 mm dan panjang 3 mm, serta yang terbuat dari titanium murni komersial (STEMA Gmbh®) diameter 2 mm dan panjang 2,2 mm; dan dibersihkan dengan kertas silika dan pembersih ultrasonik serta disterilkan dengan autoclave pada suhu 121° C selama 20 menit. Kedua sampel dimasukkan ke dalam sumur mikroplat yang mengandung 50 μl sel fibroblas dengan kepadatan 2 × 105 dalam media Rosewell Park Memorial Institute-1640 (RPMI-1640), diputar dengan kecepatan 30 rpm selama 5 menit. Sumur mikroplat diinkubasi selama 24 dan 48 jam pada suhu 37° C. Setelah 24 "> jam, pada tiap sumur yang akan dibaca pada jam ke 24 ditambahkan 50 μl cairan yang mengandung 5mg/ml MTT dalam phosphat buffer saline (PBS), kemudian diinkubasi kembali selama 4 jam dalam CO2 10% pada suhu 37° C. Assay kolorimetri dengan MTT digunakan untuk mengetahui viabilitas populasi sel setelah 24 jam. Setiap sumur ditambahkan pelarut dimetil sulfoksida (DMSO) dan diinkubasi kembali selama 5 menit pada suhu 37° C. sumur-sumur tersebut kemudian dibaca dengan Elisa reader dengan panjang gelombang 620 nm. Langkah yang sama dilakukan pada sumur-sumur yang akan dibaca pada jam ke 48. Data kemudian ditabulasi dan dianalisis dengan menggunakan independent T-test dengan signifikansi 5%. Hasil: Penelitian ini menunjukkan presentase fibroblas hidup setelah terpapar plat rekonstruksi yang terbuat dari stainless steel adalah 61,58% setelah 24 jam dan 62,33% setelah 48 jam. Dan setelah paparan dengan plat rekonstruksi yang terbuat dari titanium murni adalah 98,69% setelah 24 jam dan 82,24% setelah 48 jam. Berdasarkan pada parameter sitotoksisitas (CD50%) kedua plat rekonstruksi baik yang terbuat dari titanium murni maupun yang terbuat dari stainless steel tipe 316L merupakan bahan yang tidak bersifat toksik terhadap fibroblas. Kesimpulan: Kedua plat rekonstruksi baik yang terbuat dari stainless steel maupun CP titanium tidak bersifat toksik terhadap fibroblas, walaupun plat stainless steel menunjukkan level sitotoksisitas yang lebih rendah daripada titanium murni. Dengan demikian plat rekonstruksi yang terbuat dari stainless steel 316 L aman digunakan sebagai bahan untuk rekonstruksi mandibula.

Orthodontic-surgical treatment of a severe class III malocclusion Pakpahan Evie Lamtiur
Dental Journal (Majalah Kedokteran Gigi) Vol. 46 No. 4 (2013): December 2013
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: Adult patient with dentofacial deformities usually need surgical orthodontic treatment. Although case of class II dentofacial deformities are more common, the need for treatment and improvement in term of facial profile is generally greater in class III patients. When a skeletal Class III malocclusion is diagnosed, orthognathic surgery is always considered if the orthodontist and patient desire complete correction of the skeletal discrepancy. Purpose: The purpose of this article were to reported a case of severe class III malocclusion and to showed the positive effect of orthognatic surgical treatment on the patient’s profile. Case: This case report describes the surgical-orthodontic treatment of a 20 year old male patient with class III dentofacial deformity. Case managements: To allow adequate surgical movement, both maxillary first premolars were extracted, and the maxillary incisors were retracted. No extractions were performed in the mandibular arch. Surgery included a Le Fort I osteotomy with 8 mm advancement, a bilateral sagittal split osteotomy with the mandibula was set back 13 mm at right side and 11 mm at left side for the correction of dental midline and chin deviation. The genioplasty treatment also was done. Conclusion: Surgical-orthodontic treatment could be chosen as a treatment option for achieving an acceptable occlusion and a good esthetic result in a patient with a Class III dentofacial deformity. Nevertheless, it should be performed by a multidisciplinary team to ensure a satisfactory outcome.Latar belakang: Pasien dewasa dengan deformitas dentofacial biasanya ditangani dengan perawatan bedah orthodonti. Walaupun kasus deformitas dentofacial klas II lebih sering dijumpai, namun kebutuhan perawatan dan keinginan untuk memperbaiki profil muka lebih tinggi pada pasien dengan kasus klas III. Untuk koreksi kelainan skeletal secara menyeluruh pada maloklusi skeletal klas III maka dibutuhkan perawatan bedah ortodonti. Tujuan: Laporan kasus ini bertujuan melaporkan penanganan kasus dengan kelainan klas III maloklusion skeletal serta memperlihatkan hasil perawatan bedah ortognati yang memperbaiki profil pasien. Kasus: Perawatan bedah ortodonti dilakukan pada pasien laki-laki (20 tahun) dengan kelainan deformitas dentofacial klas III. Tatalaksana Kasus: Dilakukan pencabutan premolar pertama rahang atas kanan dan kiri, kemudian dilakukan retraksi gigi insisif rahang atas, agar didapatkan pergerakan yang adekuat. Tidak dilakukan pencabutan gigi pada rahang bawah. Perawatan bedah yang dilakukan adalah Le Fort I osteotomy dengan memajukan rahang atas sebanyak 8mm, mandibula dimundurkan dengan tehnik bilateral sagittal split ostetomy sebanyak 13 mm disebelah kanan, dan 11 mm disebelah kiri untuk koreksi dental midline dan deviasi dagu. Pasien juga mendapatkan perawatan genioplasty. Simpulan: Bedah ortognatik dapat dipilih sebagai perawatan untuk mendapatkan oklusi dan hasil estetik yang baik pada pasien dengan deformitas dentofasial kelas III. Namun demikian, perawatan perlu dilakukan oleh tim dari multidisiplin untuk mendapatkan hasil yang memuaskan.

The management of dental fracture on tooth 61 in a child with attention deficit hyperactivity disorders Veranica Veranica; Mochamad Fahlevi Rizal
Dental Journal (Majalah Kedokteran Gigi) Vol. 43 No. 4 (2010): December 2010
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: Attention deficit hyperactivity disorder (ADHD) is often characterized as a neurobehavioral developmental disorder, impaired concentration, impaired motor skills, impulsivity, and hyperactivity, and also diagnosed as psychiatric disorders. Children with ADHD would have a tendency of the traumatized anterior teeth because of their hyperactive behavior. Dental trauma is actually one of factors causing the damages of the deciduous teeth and the permanent teeth. Dental and mouth care for children with special needs, such as children with ADHD, requires special treatment. Purpose: This study is aimed to report the case management of the dental fracture of the tooth 61 in a child with ADHD. Case: A four-year old girl suffered from both ADHD and dental fracture involving the dentin of the tooth 61. Case management: The examination of the patient with dental fracture consists of emergency examination and further investigation. The emergency examination covers general condition and clinical situation. Based on the dental radiographic assessment, it is known that the dental fracture of the tooth 61 had involved the dentine, the resorption had reached 1/3 of the apical teeth and the permanent teeth had been formed. The application of calcium hydroxide on the opened dentin is aimed to improve the formation of the secondary dentin served as pulp protector. Next, the restoration of the traumatized teeth used compomer since it does not only meet all the aesthetic requirements, but it also releases fluoride. Management of the patient’s behavior with ADHD was conducted by non-pharmacological method; tell show do (TSD) method combined with restrain method. Conclusion: It can be concluded that the application of calcium hydroxide and the restoration of the teeth with compomer could provide maximum results through the combination of TSD and restrain methods that can effectively increase the positive value to replace the negative behaviors that have been formed.Latar belakang: Gangguan pemusatan perhatian-hiperaktivitas (GPPH), sering dikarakteristikan sebagai gangguan perilaku, gangguan konsentrasi, motorik, impulsif, dan hiperaktivitas dan didiagnosa sebagai gangguan psikiatrik. Anak penderita GPPH mempunyai kecenderungan mengalami trauma gigi anterior karena perilaku hiperaktivitasnya. Trauma gigi anak merupakan salah satu penyebab kerusakan pada gigi sulung maupun pada gigi tetap. Perawatan gigi dan mulut pada anak berkebutuhan khusus seperti anak penderita GPPH memerlukan pendekatan khusus. Tujuan: Makalah ini bertujuan melaporkan kasus penatalaksanaan fraktur gigi 61 pada anak dengan GPPH. Kasus: Seorang anak perempuan berusia 4 tahun menderita GPPH dan mengalami fraktur yang melibatkan dentin pada gigi 61. Tatalaksana kasus: Pemeriksaan pasien yang mengalami fraktur terdiri dari pemeriksaan darurat dan pemeriksaan lanjutan. Pemeriksaan darurat meliputi keadaan umum dan keadaan klinis. Penilaian radiografis memperlihatkan fraktur gigi 61 melibatkan dentin, resopsi mencapai 1/3 apikal dengan benih gigi tetap telah terbentuk. Aplikasi kalsium hidroksida pada dentin terbuka bertujuan untuk meningkatkan pembentukkan dentin sekunder dan berfungsi sebagai pelindung pulpa. Restorasi gigi yang mengalami trauma menggunakan kompomer karena selain memenuhi persyaratan estetik juga melepaskan fluor. Penanganan manajemen perilaku pada anak GPPH dilakukan dengan metode non farmakologi, yaitu melalui pendekatan tell show do (TSD) yang dikombinasikan dengan metode restrain. Kesimpulan: Aplikasi kalsium hidroksida dan restorasi gigi dengan kompomer memberikan hasil maksimal, melalui kombinasi TSD dan restrain, efektif meningkatkan nilai positif untuk menggantikan perilaku negatif yang telah terbentuk.

Peroxide alkaline for cleansing the baby bottle nipple to prevent oral thrush relaps Maharani Laillyza Apriasari
Dental Journal (Majalah Kedokteran Gigi) Vol. 46 No. 2 (2013): June 2013
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: Oral candidiasis is the most prevalent opportunistic infection affecting the oral mucosa. A number of predisposing factors have the capacity to convert Candida from the normal commensal flora to a pathogenic organism. Oral candidiasis is divided into primary and secondary infection. The primary infections are restricted to the oral and perioral sites, where as secondary infections are accompanied by sistemic mucocutaneous manifestation. Oral thrush is one of the candidiasis primary infection. Some presdiposing factors of oral thrush are neonatal, old people, or where oral microflora is disturbed by the treatment with broad spectrum antibiotics. Final diagnosis is determined by fungal culture examination, although through clinical examination oral thrush can be determined by swabbing the white pseudomembran. Purpose: This case report presents about the importance of using the antiseptic cleanser for baby bottle nipple to prevent oral thrush relaps and shows about peroxide alkaline as the alternatif of antiseptic cleanser for baby bottle nipple that can substitute chlorhexidine gluconat 0.2%. Case: A baby girl, 15 months old, when she was suffering influenza the pediatry gave amoxycillin 125 mg three times a day for ten days. Then the white plaque appeared on her dorsum of tongue. The therapy was Gentian Violet 1% four times a day for ten days was applied on dorsum of the tongue. The patient was suspected to suffer alergy reaction after using nistatin oral suspension four times a day had applied for 1 day. The instruction was doing sterilization for the baby bottle nipple in boiling water. Three days after the baby was cured, the white plaque was appeared on upper n lower lips mucous. Case management: The diagnosis was Oral thrush. The therapy was Gentian violet 1% four times a day for ten days that applied on upper and lower lips mucous. The instruction was doing the sterilization for baby bottle nipple in denture cleanser contain peroxide alkaline for five minutes, then it was washed with antiseptic soap, and soaked it in boiling water. Conclusion: The baby bottle nipple sterilization on the case of Oral thrush can not only by boiling in the water, but it must be keep in the antiseptic solution before boiled in the water. It was for preventing oral thrush relaps.Latar belakang: Kandidiasis rongga mulut merupakan infeksi opurtunistik yang sering terjadi pada mukosa mulut. Banyak faktor predisposisi yang menyebabkan Candida yang awalnya merupakan flora normal dalam rongga mulut berubah menjadi organisme patogen. Kandidiasis rongga mulut dibagi menjadi infeksi primer dan sekunder. Infeksi primer terjadi pada rongga mulut dan sekitarnya, sedangkan infeksi sekunder akan diikuti oleh manifestasi mukokutan secara sistemik. Oral thrush adalah salah satu dari infeksi primer candidasis. Beberapa faktor predisposisinya adalah pada bayi, orang tua atau microflora rongga mulut terganggu karena pemakaian jenis antibiotik spektrum luas. Diagnosis akhir didapatkan dari pemeriksaan kultur jamur, meskipun diagnosis dapat ditegakkan dengan pemeriksaan klinis melalui hapusan lesi pesudomembran putih. Tujuan: Laporan kasus ini tentang pentingnya penggunaan antiseptik untuk sterilisasi dot botol bayi untuk mencegah kekambuhan oral thrush dan menunjukkan alkalin peroxida sebagai alternatif bahan antiseptik untuk sterilisasi dot botol bayi, yang mampu mengganti Klorheksidin glukonat 0,2%. Kasus: Pasien adalah bayi perempuan usia 15 bulan, selama sakit batuk pilek mendapat obat dari dokter spesialis anak amoxycillin 125 mg yang diberikan 3 kali sehari selama 10 hari. Selanjutnya tampak plak putih pada lidah. Terapi yang diberikan adalah Gentian Violet 1% yang oleskan 4 kali sehari selama 10 hari pada dorsum lidah. Hal ini disebabkan pasien diduga mengalami alergi setelah diberi nistatin suspensi 4 kali sehari. Instruksi yang dianjurkan adalah menyeteril dot botol bayi dalam rebusan air. Setelah sembuh, 3 hari kemudian muncul lagi plak putih pada mukosa bibir atas dan bawahnya. Tatalaksana kasus: Pasien didiagnosis menderita oral thrush. Terapi yang diberikan adalah Gentian Violet 1% diaplikasikan 4 x 1 selama 10 hari pada mukosa bibir atas dan bawah. Instruksi yang diberikan adalah untuk menyeteril dot botol bayi dengan pembersih gigi tiruan yang mengandung alkalin peroksida selama 5 menit, kemudian dicuci dengan sabun mandi antiseptik, dan direbus dalam air. Simpulan: Sterilisasi pada bottle nipple pada pasien anak dengan oral thrush tidak dapat dilakukan dengan hanya merebus dalam air saja, melainkan harus merendam dengan cairan antiseptik terlebih dahulu sebelum direbus dalam air. Hal ini untuk mencegah terjadinya kekambuhan pada Oral thrush.

Anti-inflammation effects of Sardinella longicep oil against paw oedema on Rattus novergicus induced by 1% carrageenan Rima Parwati Sari; Yenny Sugiharto
Dental Journal (Majalah Kedokteran Gigi) Vol. 43 No. 3 (2010): September 2010
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: People usually used non steroid anti-inflammation drugs (NSAID) such as aspirin in chronic inflammation treatment. However, using NSAID at long term therapy will cause many effects such as nausea and vomiting. Sardinella longiceps oil, on the other side, is reported as an alternative treatment for anti-inflammation since it is natural and also contained eicosapentaenoid acid (EPA) and decohexaenoic acid (DHA). Thus, it may reduce paw oedema. Purpose: The aim of this study was to know anti-inflammation effects of Sardinella longiceps oil against paw oedema of Wistar rats induced by 1% carrageenan. Methods: The samples of this research were 32 Wistar rats which were divided into four groups, in group 1, the rats were given aquadest; in group 2, the rats were given aspirin; in group 3, the rats were given 1 ml Sardinella longiceps oil; in group 4, the rats were given 1.5 ml Sardinella longiceps oil. All of the rats, nevertheless, were given intraplantar induction of 1% carrageenan into the paw of rats to induce the inflammation condition. Results: All data were tested with normality test. The normal data were then analyzed with Homogenity of Variances and also ANOVA test which result showed significant differences. The data which showed significant differences were tested again with LSD test. result then showed that group given 1 ml Sardinella longiceps oil and group given 1.5 ml Sardinella longiceps oil had no significant differences from group given aspirin, but there were significant differences between group given 1 ml Sardinella longiceps oil and group given 1.5 ml Sardinella longiceps oil, and also between group given 1.5 ml Sardinella longiceps oil and group given aquadest. Conclusion: Sardinella longiceps oil could reduce paw oedema in Wistar rats induced with 1% carrageenan.Latar belakang: Penggunaan obat anti-inflamasi non steroid (OAINS) seperti aspirin sering digunakan dalam pengobatan inflamasi kronis. Namun penggunaan OAINS dalam jangka waktu panjang akan menyebabkan efek samping seperti mual dan muntah. Di sisi lain, minyak Sardinella longiceps, dilaporkan dapat digunakan sebagai alternatif anti-inflamasi karena selain alami, juga terdapat kandungan eicosapentaenoid acid (EPA) and decohexaenoic acid (DHA) yang dapat mengurangi edema pada telapak kaki. Tujuan: Tujuan dari penelitian ini adalah mengetahui efek anti-inflamasi minyak Sardinella longiceps pada edema telapak kaki tikus Wistar yang diinduksi karagenan 1%. Metode: Sampel penelitian ini adalah 32 tikus yang dibagi ke dalam empat kelompok. Kelompok 1, tikus diberi akuades; kelompok 2, tikus diberi aspirin; kelompok 3, tikus diberi minyak Sardinella longiceps 1 ml; kelompok 4, tikus diberi minyak Sardinella longiceps 1,5 ml. Semua tikus tidak terkecuali, diinduksi intraplantar karagenan 1% secara intraplantar pada telapak kaki untuk membuat kondisi inflamasi. Hasil: Semua data dilakukan uji normalitas. Selanjutnya data yang berdistribusi normal dilakukan uji homogenitas dan juga uji ANOVA yanng hasilnya menunjukkan adanya perbedaan bermakna. Data yang menunjukkan perbedaan bermakna diuji lagi dengan LSD. Pada uji LSD menunjukkan bahwa tidak ada perbedaan bermakna antara kelompok minyak Sardinella longiceps 1 ml dengan kelompok aspirin dan kelompok minyak Sardinella longiceps 1,5 ml dengan kelompok aspirin, tetapi ada perbedaan bermakna antara kelompok minyak Sardinella longiceps 1 ml dan kelompok akuades dengan kelompok minyak Sardinella longiceps 1.5 ml group given aquadest. Kesimpulan: Sardinella longiceps dapat mengurangi edema pada telapak kaki tikus Wistar yang diinduksi karagenan 1%.

Hemolysin activities as virulence factor of Enterococcus faecalis isolated from saliva and periapical abscess (gene detection by PCR) Dewa Ayu N.P.A; Sari Dewiyani; Dessy Sulistya Ashari
Dental Journal (Majalah Kedokteran Gigi) Vol. 46 No. 1 (2013): March 2013
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: Enterococcus faecalis is a normal flora of the oral cavity, commonly detected in saliva and persistence in endodontic infections. These bacteria have diverse survival and virulence factors. Hemolysin is one of the factor and still had unclear role as a virulence factor of the Enterococcus faecalis to survive in the root canal. Purpose: The purpose of this research was to analyze the presence and activity of hemolysin gene and its activity as a virulence factor isolated from saliva and root canals with periapical abscess. Yet by understanding one of the phenotypes characters which is hemolysin, it is expected a successful endodontic treatment can be provided with the persistent of Enterococcus faecalis bacteria. Methods: Method of the research starting with the identification of Enterococcus faecalis bacteria in isolated saliva and periapical abscess was done in the first part of the study. Then the phenotypes character of Enterococcus faecalis such as gene detection and expression of hemolysin in blood agar cultures of the 60 colonies samples were performed in the later part. Results: Not all of the colonies cultured were identified as Enterococcus faecalis. All positive detection on hemolysin gene showed hemolysin expresion in both isolated samples. However, there were samples with hemolysin expression eventough no hemolysin gene detected. Hemolysin expression detection in saliva was higher due to different activation phase of hemolysin in saliva. The study with just one primer could lead to the possibility of undetected hemolysin gene, eventough there were samples that did not have hemolysin gene. The proportion of hemolysin expression in root canals were less than saliva, this could be influenced by environmental factors. However, Hemolysin was considered as important virulence factor, particularly for disease therapy. Conclusion: The conclusion of this research was hemolysin gene discovered in clinical isolated saliva and root canals samples as virulence factor of the Enterococcus faecalis, and hemolysin expression occured from both sources.Latar belakang: Bakteri Enterococcus faecalis adalah flora normal rongga mulut dan merupakan mikroorganisme yang umum dideteksi dalam saliva dan infeksi endodontik persistensi. Bakteri ini memiliki berbagai faktor survival dan virulensi. Hemolysin adalah salah satunya tetapi masih merupakan faktor virulensi yang belum terlalu jelas mekanismenya. Tujuan: Tujuan riset ini adalah untuk menganalisis keberadaan gen hemolysin dan aktifitas hemolysin Enterococcus faecalis sebagai faktor virulen yang diisolasi dari saliva dan saluran akar gigi dengan abses periapikal. Mengetahui salah satu karakter fenotip Enterococcus faecalis yaitu hemolysin diharapkan berguna untuk kesuksesan perawatan endodontik akibat pesistensinya bakteri tersebut. Metode: Penelitian diawali pada bagian pertama penelitian adalah identifikasi bakteri Enterococcus faecalis isolat saliva dan abses periapikal. Bagian kedua melihat karakter fenotip Enterococcus faecalis berupa deteksi gen hemolysin serta ekspresi hemolysin di kultur agar darah dari 60 sampel koloni. Hasil: Tidak semua kuman yang tumbuh dikultur teridentifikasi sebagai Enterococcus faecalis. Pada deteksi gen hemolysin positif menunjukkan seluruhannya terekspresi hemolysin di kedua sumber isolat klinik. Namun, terdapat sampel yang menunjukkan terekspresi hemolysin meskipun gen hemolysin tidak ada dan itu lebih banyak di saliva, walaupun tidak bermakna. Hal ini dapat disebabkan perbedaan tahap aktivasi hemolysin di saliva. Pengujian hanya dengan satu primer dapat menyebabkan kemungkinan ada gen hemolysin tetapi tidak terdeteksi. Walaupun memang ada sampel yang tidak memiliki gen hemolysin. Proporsi keberadaan ekspresi hemolysin pada saluran akar lebih sedikit dari saliva karena ekspresi hemolysin dipengaruhi faktor lingkungan. Namun demikian, Hemolysin adalah faktor viruensi yang penting khususnya untuk terapi penyakit. Kesimpulan: Kesimpulan penelitian ini adalah ditemukan gen hemolysin pada sampel isolat klinik saliva dan saluran akar sebagai faktor virulen bakteri Enterococcus faecalis serta terjadi ekspresi hemolysin dari kedua sumber tersebut.

Mengkudu (Morinda citrifolia Linn.) gel affect on post-extraction fibroblast acceleration Christian Khoswanto
Dental Journal (Majalah Kedokteran Gigi) Vol. 43 No. 1 (2010): March 2010
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: Tooth extraction is one of treatment frequently done by dentists in clinics, hospital, and even private practices. One thing that is needed to be observed after the treatment is the speed of wound recovery process. Mengkudu is commonly used as medicinal treatments, some of them to heal wounds, but there had never been research of the use of mengkudu fruit on wound recovery after tooth extraction. Purpose: The aim of this study was to investigate the effect of mengkudu gel in accelerating the escalation of fibroblast post tooth extraction on Dawley rats. Method: This study was used post test only control group design. Thirty male Dawley rats weigh between 250-300 grams, 3 months of age are being used. Tooth extraction is being done on lower left incisor. The 30 rats are divided into three groups, there are mengkudu (Morinda citrifolia Linn.) gel, poviclone iodine, and control group. The data were analyzed statistically using One-Way ANOVA and LSD. Result: The result of every tested group with Kolmogorof-Smirnov test showed p > 0.05. Examination showed there was significant difference in fibroblast amount between the group with mengkudu gel and two other groups (p < 0.05). Conclusion: The application of mengkudu gel can accelerate the escalation of fibroblast after the tooth extraction on Dawley rats.Latar Belakang: Ekstraksi gigi merupakan perawatan yang sering dilakukan oleh dokter gigi baik di klinik, rumah sakit, dan praktekpribadi. Satu hal yang perlu diperhatikan setelahpencabutan gigi adalah kecepatanpenyembuhan luka bekas cabut. Mengkudu merupakan bahan yang sering digunakan untukpengobatan, salah satu diantaranya adalah untukpenyembuhan luka, namunpenelitian untuk kesembuhan luka pasca cabut gigi yang menggunakan mengkudu belum pernah dilakukan sebelumnya. Tujuan: Tujuanpenelitian ini untuk mengetahui efek gel mengkudu dalam mempercepat peningkatan jumlah fibroblas setelah pencabutan gigi tikus Dawley. Metode: Penelitian ini menggunakan rancangan penelitian post test only control group design. Tiga puluh ekor tikus Dawley jantan, berat 250-300 gram, usia 3 bulan. Gigi yang dicabut dilakukan pada insisif rahang bawah. Tiga puluh ekor tikus Dawley dibagi dalam tiga kelompokpenelitian, yaitu gel mengkudu (Morinda citrifolia Linn.), poviclone iodine, dan kelompok kontrol. Data sampel yang didapat dianalisa menggunakan One-Way ANOVA dan LSD. Hasil: Hasil dari tes pada masing-masing group dengan menggunakan Kolmogorof-Smirnov menunjukkan p > 0,05. Hasil perhitungan menunjukkan ada perbedaan bermakna pada jumlah fibroblas antara gel mengkudu dengan 2 kelompok lain (p < 0.05). Kesimpulan: Aplikasi gel mengkudu dapat mempercepat peningkatan jumlah fibroblast setelah pencabutan gigi pada tikus Dawley.

Medication intake and its influence on salivary profile of geriatric outpatients in Cipto Mangunkusumo Hospital Yuniardini Septorini Wimardhani; Winanda Annisa; Febrina Rahmayanti
Dental Journal (Majalah Kedokteran Gigi) Vol. 45 No. 3 (2012): September 2012
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: It has been well documented that several diseases or conditions and their related medications could be the risk factors for several ailments found in the oral cavity. Increased usage of medication in elderly could have impact on quality of saliva that affects oral health, eventually cause deterioration in quality of life. Purpose: examine the salivary pH, buffering capacity, stimulated- and unstimulated salivary flow rate profile in elderly using medications. Methods: Seventy-six elderly were consented and agreed to participate in this study. Interview and medical record analysis were performed to get data about their health status, chronic use of medications and complaints related to xerostomia. Collection of unstimulated and stimulated saliva samples were completed in parallel with measurement of salivary pH and buffering capacity. Results: The mean salivary pH was moderately acidic while having low salivary buffering capacity. The mean unstimulated salivary flow rate (USSFR) was 0.24 ± 1.8ml/min and 41of subjects (53%) were classified hyposalivation, while the stimulated salivary flow rate (SSFR) was 0.86 ± 0.49ml/min and 31 (40%) classified hyposalivation. Number of drugs-induced xerostomia intake significantly correlated with the reduction in the USSFR of subjects (p<0.0001), however it was not the case with salivary pH and buffering capacity (p>0.05). It also showed correlation with complaints related to xerostomia. The mean USSFR did not correlate with xerostomia complaints. Conclusion: Medications intake influenced salivary profile and had more effect in changes in xerostomia complaints and salivary quantity than to salivary pH and buffering capacity in Indonesian elderly population.Latar belakang: Telah lama diketahui bahwa beberapa penyakit atau kondisi sistemik dan medikasinya dapat menjadi faktor resiko terjadinya beberapa kelainan dalam rongga mulut. Meningkatnya penggunaan medikasi sistemik pada lansia dapat mempengaruhi kualitas saliva sehingga berpengaruh pada kesehatan mulut yang akhirnya menyebabkan menurunnya kualitas hidup. Tujuan: Mengetahui profil pH saliva, kapasitas dapar, laju aliran saliva terstimulasi (LAST) dan tanpa stimulasi (LASTS) pada lansia yang mendapatkan medikasi sistemik. Metode: Tujuh puluh enam lansia telah menandatangani inform consent dan setuju untuk berpartisipasi. Wawancara dan analsis rekam medis dilakukan untuk mendapatkan data tentang status kesehatan, penggunaan medikasi sistemik jangka panjang dan keluhan xerostomia. Pengumpulan saliva tanpa stimulasi dan terstimulasi dilakukan bersama-sama dengan pengukuran pH dan kapasitas dapar. Hasil: pH saliva subyek adalah berada dalam kelompok asam sedang dengan kapasitas dapar yang rendah. Rerata LASTS adalah 0,24 ± 1,8ml/menit dan 41 subyek (53%) mengalami hiposalivasi, sementara LAST adalah 0,86 ± 0,49ml/menit dan 31 subyek (40%) mengalami hiposalivasi. Jumlah medikasi yang dapat menginduksi xerostomia secara bermakna berhubungan dengan penurunan LASTS (p < 0,0001), namun tidak demikian dengan pH dan kapasitas dapar (p>0,05). Medikasi sistemik juga berhubungan dengan keluhan yang terkait xerostomia. Rerata LASTS tidak berhubungan dengan keluhan xerostomia. Kesimpulan: Medikasi sistemik pada populasi lansia Indonesia mempengaruhi profil saliva dan mempunyai pengaruh yang lebih besar pada keluhan xerostomia dan kuantitas saliva dibandingkan pH dan kapasitas dapar.

Trans-adapted, reliability, and validity of children fear survey schedule-dental subscale in Bahasa Indonesia Arlette Suzy; Julian Amriwijaya; Efi Fitriana
Dental Journal (Majalah Kedokteran Gigi) Vol. 48 No. 1 (2015): March 2015
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: The most frequently used measuring instrument for determination of dental fear in children nowadays is the children’s fear survey schedule-dental scale (CFSS-DS). Purpose: The purpose of this study was to explore the reliability and validity of the scale with Indonesian trans adapted version of the scale, thus the scale can be reliable to be used in other similar research in Indonesia. Methods: Total of 113 participants, who were parent’s 3 to 12 years old children. Children were divided into two age groups, group I 3-6 year old (83 children) and group II 7-12 year old (30 children). Eighty three children from the first group were divided into first dental visit group (30 children) and non first dental visit group (53 children). Test-retest approach was applied to 30 first dental visit children aged 3-6 year old. Original scale was translated to Indonesian language. Result: The result showed the high value of the Cronbach’s coefficient of internal consistency α=0.956. Three factors were extracted by screen test method with Eigen values higher than 1, which explained 93.05% variance of results. Conclusion: CFSS-DS scale is reliable and valid psychometric instrument for dental fear evaluation in children in Bahasa Indonesia. The differences between this study and those of others may appear due to many factors.

Deoxypyridinoline level in gingival crevicular fluid as alveolar bone loss biomarker in periodontal disease Agustin Wulan Suci Dharmayanti
Dental Journal (Majalah Kedokteran Gigi) Vol. 45 No. 2 (2012): June 2012
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: Periodontal diseases have high prevalence in Indonesia. They are caused by bacteria plaque that induced host response to release pro inflammatory mediator. Pro inflammatory mediators and bacteria product cause degradation of collagen fibers in periodontal tissue. Deoxypyridinoline is one of pyridinoline cross-link of collagen type I that can be used as biomarker in bone metabolic diseases, however, their contribution to detect alveolar bone loss in periodontal diseases remains unclear. Purpose: This study was to evaluate deoxypyridinoline level in gingival crevicular fluid as alveolar bone loss biomarker on periodontal disease. Methods: This study used 24 subjects with periodontal diseases and 6 healthy subjects. Dividing of periodontal disease was based on index periodontal. Gingival crevicular fluid was taken at mesial site of maxillary posterior tooth by paper point and deoxypyridinoline be measured by ELISA technique. Results: We found increasing of deoxypyridinoline level following of the severity of periodontal diseases. There was also significant difference between healthy subjects and periodontal diseases subjects (p<0.05). Conclusion: Deoxypyridinoline level in gingiva crevicular fluid can be used as alveolar bone loss biomarker in periodontal disease subjects.Latar belakang: Prevalensi penyakit periodontal di Indonesia cukup tinggi. Ini disebabkan oleh bakteri plak yang merangsang respon tubuh untuk mengeluarkan mediator keradangan. Mediator keradangan dan produk bakteri menyebabkan degradasi serat kolagen jaringan periodontal. Deoksipiridinolin merupakan salah satu ikatan piridinium dari kolagen tipe I yang dapat digunakan sebagai biomarker penyakit metabolisme tubuh. Akan tetapi, penggunaan deoksipiridinolin untuk mendeteksi kehilangan tulang alveolar pada penyakit periodontal masih belum jelas. Tujuan: Tujuan penelitian ini untuk mengetahui bahwa kadar deoksipiridinolin pada cairan krevikular gingival dapat digunakan sebagai biomarker kehilangan tulang alveolar pada penyakit periodontal. Metode: Penelitian ini menggunakan 24 subyek penelitian yaitu 24 orang dengan penyakit periodontal dan 6 orang tidak menderita penyakit periodontal. Pembagian penyakit periodontal berdasarkan indeks periodontal. Cairan krevikular gingival diambil dari bagian mesial gigi posterior atas dengan menggunakan paper point dan diukur kadar deoksipiridinolin dengan menggunakan teknik ELISA. Hasil: Hasil penelitian menunjukkan ada peningkatan kadar deoksipiridinolin seiring dengan tingkat keparahan penyakit periodontal. Hasil statistik juga menunjukkan ada perbedaan rata-rata antara subyek penelitian yang tidak menderita penyakit dengan subyek yang menderita penyakit periodontal (p<0,05). Kesimpulan: Kadar deoksipiridinolin pada cairan krevikular gingival dapat digunakan sebagai biomarker kehilangan tulang alveolar pada penderita penyakit periodontal.

Page 13 of 95 | Total Record : 950

11 12 13 14 15

Filter by Year

2005 2025

Filter By Issues

All Issue Vol. 58 No. 4 (2025): December Vol. 58 No. 3 (2025): September Vol. 58 No. 2 (2025): June Vol. 58 No. 1 (2025): March Vol. 57 No. 4 (2024): December Vol. 57 No. 3 (2024): September Vol. 57 No. 2 (2024): June Vol. 57 No. 1 (2024): March Vol. 56 No. 2 (2023): June 2023 Vol. 56 No. 1 (2023): March 2023 Vol. 56 No. 4 (2023): December Vol. 56 No. 3 (2023): September Vol. 55 No. 4 (2022): December 2022 Vol. 55 No. 3 (2022): September 2022 Vol. 55 No. 2 (2022): June 2022 Vol. 55 No. 1 (2022): March 2022 Vol. 54 No. 4 (2021): December 2021 Vol. 54 No. 3 (2021): September 2021 Vol. 54 No. 2 (2021): June 2021 Vol. 54 No. 1 (2021): March 2021 Vol. 53 No. 4 (2020): December 2020 Vol. 53 No. 3 (2020): September 2020 Vol. 53 No. 2 (2020): June 2020 Vol. 53 No. 1 (2020): March 2020 Vol. 52 No. 4 (2019): December 2019 Vol. 52 No. 3 (2019): September 2019 Vol. 52 No. 2 (2019): June 2019 Vol. 52 No. 1 (2019): March 2019 Vol. 51 No. 4 (2018): December 2018 Vol. 51 No. 3 (2018): September 2018 Vol. 51 No. 2 (2018): June 2018 Vol. 51 No. 1 (2018): March 2018 Vol. 50 No. 4 (2017): December 2017 Vol. 50 No. 3 (2017): September 2017 Vol. 50 No. 2 (2017): June 2017 Vol. 50 No. 1 (2017): March 2017 Vol. 49 No. 4 (2016): December 2016 Vol. 49 No. 3 (2016): September 2016 Vol. 49 No. 2 (2016): June 2016 Vol. 49 No. 1 (2016): March 2016 Vol. 48 No. 4 (2015): December 2015 Vol. 48 No. 3 (2015): September 2015 Vol. 48 No. 2 (2015): June 2015 Vol. 48 No. 1 (2015): March 2015 Vol. 47 No. 4 (2014): December 2014 Vol. 47 No. 3 (2014): September 2014 Vol. 47 No. 2 (2014): June 2014 Vol. 47 No. 1 (2014): March 2014 Vol. 46 No. 4 (2013): December 2013 Vol. 46 No. 3 (2013): September 2013 Vol. 46 No. 2 (2013): June 2013 Vol. 46 No. 1 (2013): March 2013 Vol. 45 No. 4 (2012): December 2012 Vol. 45 No. 3 (2012): September 2012 Vol. 45 No. 2 (2012): June 2012 Vol. 45 No. 1 (2012): March 2012 Vol. 44 No. 4 (2011): December 2011 Vol. 44 No. 3 (2011): September 2011 Vol. 44 No. 2 (2011): June 2011 Vol. 44 No. 1 (2011): March 2011 Vol. 43 No. 4 (2010): December 2010 Vol. 43 No. 3 (2010): September 2010 Vol. 43 No. 2 (2010): June 2010 Vol. 43 No. 1 (2010): March 2010 Vol. 42 No. 4 (2009): December 2009 Vol. 42 No. 3 (2009): September 2009 Vol. 42 No. 2 (2009): June 2009 Vol. 42 No. 1 (2009): March 2009 Vol. 41 No. 4 (2008): December 2008 Vol. 41 No. 3 (2008): September 2008 Vol. 41 No. 2 (2008): June 2008 Vol. 41 No. 1 (2008): March 2008 Vol. 40 No. 4 (2007): December 2007 Vol. 40 No. 3 (2007): September 2007 Vol. 40 No. 2 (2007): June 2007 Vol. 40 No. 1 (2007): March 2007 Vol. 39 No. 4 (2006): December 2006 Vol. 39 No. 3 (2006): September 2006 Vol. 39 No. 2 (2006): June 2006 Vol. 39 No. 1 (2006): March 2006 Vol. 38 No. 4 (2005): December 2005 Vol. 38 No. 3 (2005): September 2005 Vol. 38 No. 2 (2005): June 2005 Vol. 38 No. 1 (2005): March 2005 More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
Saka Winias

Contact Email
saka.winias@gmail.com

Phone
-

Journal Mail Official
dental_journal@yahoo.com

Editorial Address
-

Location
Kota surabaya,

Jawa timur

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Saka Winias

Contact Email saka.winias@gmail.com

Phone -

Journal Mail Official dental_journal@yahoo.com

Editorial Address -

Location Kota surabaya, Jawa timur INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Saka Winias

Contact Email
saka.winias@gmail.com

Phone
-

Journal Mail Official
dental_journal@yahoo.com

Editorial Address
-

Location
Kota surabaya,

Jawa timur

INDONESIA