cover
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kota denpasar,
Bali
INDONESIA
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES
Published by Universitas Udayana
ISSN : 20854773     EISSN : 23022906     DOI : -
Core Subject : Health,
Indonesia Journal of Biomedical Science (IJBS), Print-ISSN 2085-4773; E-ISSN 2302-2906 is an international and peer-reviewed journal published twice per year in print and online by Indonesian of Biomedical Association in collaboration to Postgraduate School of Biomedicine Udayana University, Bali-Indonesia which was founded in 2007. The Journal aims to bridge and integrate the intellectual, methodological, and substantive diversity of biomedical scholarship, and to encourage a vigorous dialogue between biomedical scholars and researches. The Journal welcomes contributions which promote the exchange of ideas and rational discourse between practicing educators and biomedical researchers all over the world.
Arjuna Subject : -
Articles 87 Documents
COMPARISON STUDY IN USING PLOUGH, TRACTOR AND CULTIVATOR FOR RICE FIELD’ LAND PREPARATION Sutjana, I.D.P.; Adiputra, I Nyoman
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol. 2, No. 1 Maret 2008
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (81.535 KB)

Abstract

Land preparation of the rice field is one of the most important steps for paddyplantation. Formerly plough is one of the main tools for land preparation, but now thefarmer used tractor or cultivator. From the farmer experience who are used that tools forland preparation there had advantages and disadvantages. The used of plough for landpreparation for long time ago the deep of rice field soil is constant because the ploughblade can be adjusted up and down. The plough can be turn to the right or left side so thatall part of rice field except the corner can be cultivate. But for pulling the plough must bedifficult to find two cows. While if using tractor or cultivator the right or left side and thecorner of the rice field can’t be cultivate. Deep of rice filed soil become shallow so thefertility of soil reduced. Beside that using tractor or cultivator for land preparation needmore fuel. The plough were easy to carry out, but tractor and cultivator difficult to carryout because the weight more that 200 kg.
FLOUXETINE IMPROVED INTRAVAGINAL EJACULATORY LATENCY TIME THROUGH DECREASED LEVELS OF INTERFERON-GAMMA AND INCREASED LEVELS OF SEROTONIN IN PATIENT WITH PREMATURE EJACULATION I M., Nyandra; W, Pangkahila; A. A., Raka-Sudewi; I N. A., Bagiada
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol 6 No 2 (2012): Indonesian Journal of Biomedical Sciences
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (584.199 KB)

Abstract

Pathophysiology of premature ejaculation (PE) is very complex because it is associated with many factors, which can be grouped into biological factors and psychological factors. Various diseases have been found correlate between psychological factors and biological factors through cytokines, one of which is IFN-g (IFN-g). IFN-g affect indolamine dioxygenase enzyme (IDO) and decrease levels of serotonin. Low levels of serotonin leads to PE. The purpose of this study was to prove the relationship of serotonin and IFN-g in pathophysiology of PE. This study was designed as a pretest-posttest double-blind cross-over control group design. Patients with PE were divided into 2 groups: control group and treatment group. Treatment group received flouxetine 20 mg for 30 days. Then the control and treatment groups were crossed after passing a 14-days washout period. Previously as a control group to treatment group and received flouxetine 20 mg per day for 30 days. Before and after treatment in each group was examined the levels of serotonin and IFN-g. Of the 26 subjects, each group there was 13 subjects. Flouxetine 20 mg per day for 30 days increased serotonin levels were significantly (p < 0.05), and decreased levels of IFN-g were significantly (p < 0.05). Increased levels of serotonin and decreased levels of IFN-g was significantly associated with improvements (intravaginal ejaculatory latency time) ejaculation in PE patient. From these results it can be concluded that PE occurs because decreased levels of serotonin. Decreased levels of serotonin are associated with increased levels of IFN-g. Keywords: PE, Serotonin, IFN-g.
INHIBITION OF BIFIDOBACTERIUM sp ISOLATED FROM INFANTS FECES TOWARDS ADHESION OF SALMONELLA TYPHI ON BALB/c MICE ENTEROCYTE Sukrama, I D. M.; Sukardika, K.; -, Sumarno; Mantik Astawa, N.
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol. 4, No. 1 Januari 2010
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (68.698 KB)

Abstract

Diarrhea, up to the recent year remains a cause of high morbidity and mortalityworldwide, especially in developing countries including Indonesia. Research concerning ofmanagement, prevention, and medication of the disease have been continually improved. Theaim of this research is searching Bifidobacterium sp isolated from infants feces. ThisBifidobacterium was then applied as an anti-adhesion of Salmonella typhi in the hope to gain acure of diarrhea. This research employed two research designs, namely descriptive explorationand true experimental. Exploration was applied in order to obtain isolation and characterizationof Bifidobacterium isolated from infants feces. Adherence ability of this Bifidobacterium sptowards Salmonella typhi adhesion on mice entherocyte was then carried out by applyingRandomized Posttest-Only Control Group Design. In this research, average Bifidobacterium spadhesion index of 1950 on entherocyte was obtained. In simple word, there are 19.5Bifidobacteria adhere to any single entherocyte cell. This adhesion index value is highercompare to Salmonella typhi adhesion of 1504. Conclusions that can be drawn from this researchare the finding of Bifidobacterium sp isolated from infants feces. This Bifidobacterium sp has anability to inhibit adhesion of Salmonella typhi on BALB/c mice enterocyte. Future work that canbe carried out are further researches concerning whether these bacteria have an ability to inhibitadherence of other pathogen bacteria. More over, searching of cell wall adhesin ofBifidobacterium sp that can be used as a replacement of life probiotic bacteria is also a greatinterest of research to be carried out.
PERBAIKAN KONDISI KERJA DENGAN PENDEKATAN ERGONOMI TOTAL MENURUNKAN KELUHAN MUSKULOSKELETAL DAN KELELAHAN SERTA MENINGKATKAN PRODUKTIVITAS DAN PENGHASILAN PERAJIN PENGECATAN LOGAM DI KEDIRI-TABANAN Adiatmika, I P G; Manuaba, A.; Adiputra, N.; Sutjana, D.P.
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol. 1, No. 3 Desember 2007
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (53.624 KB)

Abstract

Perubahan ekonomi dunia menuntut daya saing setiap perajin khususnya di Bali. Salah satudaya saing yang diusahakan adalah produksi tepat waktu. Produksi tepat waktu sebagianbesar dilakukan dengan kerja lembur seperti perajin pengecatan logam di Kediri Tabanan.Hal ini disebabkan produktivitas dan penghasilan mereka masih di bawah standar. Untuk itudperlukan suatu perbaikan dengan pendekatan ergonomi sehingga mampu bersaing,manusiawi dan berkelanjutan. Banyak perbaikan sudah dilakukan tetapi masih terjadimasalah sehingga diperlukan perbaikan secara komprehensif. Salah satu cara perbaikanadalah dengan melalui pendekatan ergonomi total. Tujuan untuk mengetahui pengaruhpendekatan ergonomi total terhadap keluhan muskuloskeletal dan kelelahan sertaproduktivitas dan penghasilan perajin. Subyek penelitian adalah 24 karyawan pengecatankerajinan logam di Kediri Tabanan pada bulan September 2007 – Maret 2007 denganrancangan sama subyek. Kondisi kerja diperbaiki dengan model pendekatan ergonomi totalsehingga diperoleh bentuk perbaikan yang paling optimal. Hasil menunjukkan adapenurunan keluhan muskuloskeletal 5,53 % dan penurunan kelelahan 6,79 % secarabermakna (p<0,05). Produktivitas karyawan meningkat 61,36% dan penghasilan perajinmeningkat 55,29% secara bermakna (p<0,05). Perubahan yang terjadi sebagai dampak dariperbaikan kondisi kerja dengan model pendekatan ergonomi total lebih besar terjadi padaproduktivitas dan penghasilan. Disimpulkan pendekatan ergonomi total menurunkankeluhan muskuloskeletal dan kelelahan serta meningkatkan produktivitas dan penghasilanperajin. Disarankan untuk menerapkan model pendekatan ergonomi total pada industri yanglain dan mendorong partisipasi aktif karyawan dalam perbaikan kondisi kerja.
THE ROLE OF INTENSIVE INSULIN THERAPY ON SUPEROXIDE DISMUTASE (SOD), TUMOR NECROSIS FACTOR-? (TNF-?), AND INTERLEUKIN-6 (IL-6) ON HYPERGLYCEMIA IN CRITICALLY ILL PATIENTS Wiryana, Made; Suastika, Ketut; Bagianto, Hari; Bakta, Made
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol. 3, No. 1 Januari 2009
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (217.01 KB)

Abstract

Hyperglycemia and insulin resistance are common in critically ill patientsin the ICU, although they have not previously had diabetes. It has been reportedthat pronounced hyperglycemia may lead to complications in such patients, andcause the reactive oxygen species (ROS) production, although controlled trial dataare still lacking. The current debatable issue, focusing on whether the intensiveinsulin therapy, aimed at normalizing blood glucose, may improvepatients’prognosis. Then, the debate is mainly about the time to start the therapy,and target of blood glucose level. Therefore, this research is mainly designed andaimed at knowing the difference between intensive insulin therapy andconventional insulin therapy on the increase of superoxide dismutase (SOD),decrease of cytokine production (TNF-? and IL-6), increase of albumin level, andevent of SIRSThis study was carried out in a randomly pre and post-test control groupdesign, involving 40 adult patients being nursed through the ICU Sanglah hospitalDenpasar. They were randomly assigned to receive intensive insulin therapy, inwhich blood glucose was decreased and maintained at the level between 80-110mg/dl, or conventional insulin therapy in which the insulin was infused only if theblood glucose level exceeded 215 mg/dl, decreased and maintained then at thelevel between 180-200 mg/dl.The result of the study showed that there was (1) significant increase ofSOD mean level (370. 70 vs 98.50 U/gHb, p=0.001); (2) no significant decreaseof TNF-? mean level; (3) significant decrease of IL-6 mean level (10.26 vs 2.25;p=0.023); (4) significant increase of albumin mean level ( 0.62 vs 0.22); (5)significant decrease of SIRS (10 % vs 40 %, p=0.000) on intensive insulin therapygroup compared to conventional insulin therapy group. It can be concluded thatintensive insulin therapy could maintain blood glucose level between 80 – 110mg/dl, increase SOD level, decrease IL-6 level, increase albumin level, anddecrease SIRS on hyperglycemia in critically ill ICU patients.
THE HUMORAL IMMUNITY RESPONSE OF DOG VACCINATED WITH ORAL SAG2 AND PARENTERAL RABISIN AND RABIVET SUPRA92 -, Faizah; Mantik-Astawa, IN; Putra, AAG; -, Suwarno
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol. 6, No. 1 Januari 2012
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (181.246 KB)

Abstract

ABSTRACT This research aims to determine whether SAG2 oral vaccine induced antibody response as high as that of parenteral vaccine (Rabisin and Rabivet Supra 92). The experimental design applied was randomized pre and post control group design with 4 treatments (oral SAG2 vaccine, parenteral rabisin, parenteral Rabivet Supra 92 and control without vaccination) and with 9 replication. As many as 36 kampung dogs used and the anti rabies antibody was determined by enzyme-linked immunosorbent assay (ELISA) at day 0, 21, 56, 84, 119, and 147 post vaccination. The antibody titer induced by oral SAG2 vaccine raised more slowly but persisted longer than parenteral vaccine. On day 21 after vaccination, the average antibody titers induced by oral SAG2 vaccines (0.501 IU/ml) was still significantly lower than those induced by parenteral Rabisin (3.504 IU/ml) and Rabivet Supra92 (2.545 IU/ml). However, by day 119 after vaccination the average antibody titer induced by SAG2 oral vaccine (0.889 IU/ml) was significantly higher (p <0.05) as compared to those of parenteral Rabisin (0.625 IU/ml) and Rabivet Supra 92 (0.223 IU/ml). The antibody response induced by SAG2 oral vaccine appears to persist longer than parenteral vaccines and it can therefore be used as an alternative vaccine to combat rabies in animals, especially for dogs kept in free range.
STEROID FOR MANAGEMENT OF PSEUDO-OTHEMATOMA Sudana, Wayan; Adiputra, Nyoman; Wiyadi, H.M.S.
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol. 5, No. 1 Januari 2011
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (83.538 KB)

Abstract

Has conducted research on the use of steroids triamsinolon asetonid as pseudo-othematomamedical therapy. The purpose of this study was to determine the effectiveness triamsinolonasetonid. Prevention of the formation of serum in the lesion, so that pseudo-othematomacan be cured without surgery. Surgery and preventing of the formation collagen tissue inthe lesion, so that the pseudo-othematoma can be cured without deformity. It is expectedthe establishment of a pseudo-othematoma practical for health personnel, effective,efficient, safe and comfortable for the patient. This study design is the design of arandomized controled pretest-postest design. In the test group were treated withtriamsinolon asetonid intracutaneus injected in lesion area with the number according tothe percentage of the amount of teraphy effusion before. Then press verban installed. In thecontrol group, only pressing verban installed. From the research results obtained, whishafter the third treatment using the triamsinolon asetonid, pseudo-othematoma diseaselooked very meaningful. Due to its unique histological structure of the ear, then themanipulation of the ear is moe advisable to be careful, to prevent new lession with variousimpacts.
IODINE LEVEL OF IODIZED SALT REQUIRED IN ENDEMIC AREA Gunung, I Komang
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol. 2, No. 2 Mei 2008
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (135.674 KB)

Abstract

Iodized salt had been used in many countries for long term iodine deficiency disorders (IDD) control program. Several things should be considered related to iodine loss in iodized salt, e.g. iodine loss during cooking that may effect the effectivity of the program. Too high iodine level on the other hand, will cause health problems such as iodine-induced hyperthyroidism (IIH) and autoimmune thyroiditis. The purpose of this study was to know the level of iodine in iodized salt required in endemic area to meet the iodine recommended daily allowance (RDA) of 150 ?g/person/day. This study was a field trials using treatment by subyect design. Ten schoolchildren were selected systematically to get ten clusters of schoolchildren families. All members of the families were 33 persons (2 families were droped out). Urine examination showed the mean of urine iodine excretion (UIE) 84.8 ± 32.11 ?g/L and 208.1 ± 89.24 ?g/L of non-iodized salt and iodized salt consumption respectively. Salt intake was 6.64 g/person/day and iodine loss during cooking was 25%. Iodine level of iodized salt required in mild endemic area was 22 ppm at consumer level or 32 ppm at production level. This result was slightly higher than the minimum range (30 ppm) and much lower than the maximum range (80 ppm) was the level of iodine in iodized salt that was detemined by the government (30-80 ppm). Based on this finding, the range of iodine level in iodized salt production should be rivised according to the endemicity of area (mild, moderate, and severe).
ORAL ADMINISTRATION OF PEPPERMINT IN WISTAR ALBINO RATS: Memory Boosting and Regaining Jasira, M.; Sai-Sailesh, K.; Mukkadan, and J. K.
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol 7 No 1 (2013): IJBS Vol.7 No.1 January-June 2013
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (504.371 KB)

Abstract

The studies on peppermint aroma fluence on cognition are numerous. However the knowledge about oral consumption of peppermint and cognition was inadequate. Hence the present study was undertaken to find out the effect of oral administration of peppermint spices in memory boosting and memory regaining on adult wistar rats. Here we investigate the influence of oral intake of peppermint on behavioral task performance by using T-maze and radial arm maze and physiological measures relative to a milk control group. We have observed significant memory boosting and memory regaining effects of peppermint when administered orally. This effect may be due to improvement of the blood flow to the brain and increasing the concentration power.  Hence we recommend further research in this area by investigating compound metabolism to optimize quantification of memory performance following peppermint ingestion.
ERGONOMIC INTERVENTION DECREASES THE LOAD OF LEARNING AND INCREASES THE STUDENTS PERFORMANCES Pungus, Meity; Manuaba, Adnyana; Adiputra, Nyoman; Tirtayasa, Ketut
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol. 4, No. 2 Juli 2010
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (36.096 KB)

Abstract

Most students’ activities in respect to the implementation of the academic curriculumare done at home. In fact, conventional activity done by the students in boardinghouse ofMinahasa tradition showed unfavorable risks to students based on the load of learning withindicators of musculoskeletal complaints, boredom, and fatigue. Consequently, thestudents were not yet able to attain the intended performance. To overcome the problems,it has made the efforts of ergonomics intervention. In order to test the capability of theergonomics interventions, it had been done a research with the hypothesis, the ergonomicsinterventions on the activity in boardinghouse of Minahasa tradition: normalizes the bodytemperature; decreases the musculoskeletal complaints; decreases the level of boredom;decreases the level of fatigue; increases the accuracy of working; increases the speed ofworking; increases the constancy of working; and increases the results of working of thestudents. This research was done in two periods by utilizing the treatment by subjectdesign. The first and second period was done during four weeks, without and withergonomic intervention. The subjects utilized in the research were as many as 15 persons.The measurements of dependent variables were done before and after doing the activity.The results of the research showed that the ergonomics interventions on the learningactivities in boardinghouse could decrease load of learning significantly (p<0.05): the bodytemperature became normal, the musculoskeletal complaints decreased 44.79%; the levelof boredom decreased 9.79%; the level of fatigue decreased 15.20%; the accuracy ofworking decreased 55.06%; the speed of working decreased 17.32%; the constancy ofworking decreased 30.72%; and the results of working of the students increased 131.44%.It can be concluded that the ergonomics interventions can: decrease the load of learning ofthe students and increase the performance of the students.