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INDONESIA
IDJP (Indonesian Journal of Pharmaceutics)
Published by Universitas Padjadjaran
ISSN : -     EISSN : 25978748     DOI : -
Core Subject :
The Indonesian Journal of Pharmaceutics (IdJP) is an established international journal for pharmaceutical scientists concerned in all fields of pharmaceutical sciences, including pharmaceutical preformulation, formulation, manufacturing technologies, drug delivery systems, biopharmaceutics, and pharmacokinetics for drugs, vaccines and biologicals. IdJP also includes pharmaceutical engineering and industrial pharmacy topics.
Arjuna Subject : -
Articles 5 Documents
 1 
Search results for , issue "Vol 6, Issue 1, Jan - April 2024" : 5 Documents clear
Formulation of Black Garlic Tea with The Addition of Ginger (Zingiber officinale), Rosella (Hibiscus sabdariffa L), and Packaging Design Putriana, Norisca Aliza; Mardawati, Efri; Rizki Sendi, Cahyani; Maulida Rahmah, Devi; Pujianto, Totok; Marta, Herlina
Indonesian Journal of Pharmaceutics Vol 6, Issue 1, Jan - April 2024
Publisher : Universitas Padjadjaran (Unpad)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/idjp.v6i1.52667

Abstract

Indonesia is globally recognized for its abundant biodiversity and is considered one of the most biodiverse countries in the world. Over centuries, local communities have explored the benefits of natural ingredients such as garlic to be used as herbal medicine. Although garlic has numerous health benefits, raw consumption is still uncommon due to its strong aroma and taste. To address this issue, black garlic, a derived product from garlic, has been developed to minimize its strong characteristics. Therefore, this research aimed to investigate formulation of black garlic tea with the addition of ginger and rosella flowers in terms of bioactive components, including total phenolic content, total flavonoid content, antioxidant activity, and organoleptic characteristics of taste and aroma. The method used involved the extraction of 12 samples. The results indicated that the highest phenolic content was 16.708 ± 0.0356 mg GAE/g with formulation of black garlic, rosella, and ginger at a ratio of 1 g: 3 g: 2 g. The highest flavonoid content was observed in formulation of black garlic, rosella, and ginger at a ratio of 2 g: 3 g: 2 g, which amounted to 13.560 ± 0.536 mg QE/g. Furthermore, formulation with black garlic, rosella, and ginger at a ratio of 2 g: 3 g: 2 g exhibited the highest antioxidant activity of 63.21%. These results showed that formulation of black garlic tea with the addition of ginger and rosella flowers could enhance the levels of bioactive components, including total phenolic content, total flavonoid content, and antioxidant activity.
 Antioxidant Potential of Usnea spp. Extract with Lysozyme Conjugation for the Prevention of Chronic Kidney Disease Progression Junior, Darren; Dewi, Luh Putu Widya Amritha; Indratmo, Novea; Indrayani, Agung Wiwiek
Indonesian Journal of Pharmaceutics Vol 6, Issue 1, Jan - April 2024
Publisher : Universitas Padjadjaran (Unpad)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/idjp.v6i1.57697

Abstract

The prevalence of chronic kidney disease worldwide has been reported to increase every year with hypertension serving as the leading cause. The recommended treatment for chronic kidney disease patients with a history of hypertension is antihypertensive medications, which could cause side effects from prolonged use. Hence, the authors sought out a possible novel modality by implementing antioxidant properties from beard lichen (Usnea spp.) extract. Literature search was conducted on trusted scientific databases, including Google Scholar, PubMed, DOAJ, and Cochrane. The pathophysiology of hypertension in the progression of chronic kidney disease could mainly be attributed to the presence of inflammation and oxidative stress, which could be attenuated by the use of antioxidants. Lichens are a class of complex living organisms resulting from a symbiosis that allows them to synthesize various beneficial phytochemicals. Usnic and stictic acid derived from Usnea spp. are part of phenolic compounds that display strong antioxidant activities. In order for these antioxidants to have a focused effect on the kidneys, a kidney-targeted drug delivery system should be considered with lysozyme conjugation being the most studied method. The combination of Usnea spp. extract’s antioxidant capabilities with lysozyme conjugation could serve as a potential novel modality in the specific prevention of chronic kidney disease progression.                 Keywords: antioxidant; chronic kidney disease; lysozyme conjugation; Usnea                       spp. 
A Literature Review Of Nanocarrier Development Through Emulsification Diffusion Method (Edm) arafat, Md yeasin; Nijhu, Rajia Sultana
Indonesian Journal of Pharmaceutics Vol 6, Issue 1, Jan - April 2024
Publisher : Universitas Padjadjaran (Unpad)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/idjp.v6i1.55950

Abstract

An overview of the development of nanocarriers is presented in this work using the practical technique of the Emulsification Diffusion Method (EDM). The field of nanomedicine, which combines nanotechnology and medicine, involves creating new therapeutic and diagnostic modalities by employing precisely designed substances with this range of lengths. Many medicinal products and diagnostic tools based on nanoparticles have been developed. The emulsification-diffusion method (EDM) was utilized to prepare nanometer-sized particles, which are commonly used as polymeric carriers. The process involves emulsifying a drug and polymer solution in an aqueous phase that has been saturated with stabilizers and then adding an excessive amount of water.  Investigations into how process variables affect the average size of nanoparticles have been carried out. It was made apparent that the kind and concentrations of stabilizer, the speed at which the magnetic stirrer homogenizes, and the polymer concentration all affected the size of the nanoparticles. Additionally, the medications integrated into nanocarriers have a longer half-life in circulation, which boosts their effectiveness and allows for a lower application dose. Because of their small size and high surface area, drug nanocarriers are also more bioavailable and soluble, which allows their many atoms and high surface energy to act as catalysts. Keywords: Nanocarrier,Diffusion,Bioavailability,Solubility,Catalysts.
Towards Standardized Hydration Testing Protocols for Natural Product-Based Nanoemulgel Moisturizers: A Systematic Review Iskandar, Benni; Eka Saputri Nst, Sandry; Inggrid. P, Debora; Ami Sari, Rosi; Pulpa Susila, Afriani
Indonesian Journal of Pharmaceutics Vol 6, Issue 1, Jan - April 2024
Publisher : Universitas Padjadjaran (Unpad)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/idjp.v6i1.59266

Abstract

The growing complexity of moisturizer formulations, particularly those incorporating natural product-based nanoemulgels, highlights an urgent need for standardized efficacy evaluation methods. This systematic review critically examines hydration testing methodologies used for natural ingredient-based nanoemulgel moisturizers, with a focus on their validity, reliability, and practical application. Through a comprehensive analysis of 32 peer-reviewed articles published between 2000 and 2023, this study identified several key limitations in current practices, including inconsistent testing conditions, the absence of standardized protocols for assessing natural ingredients, and variability in reporting methods. The findings emphasize the necessity of developing robust, standardized hydration testing protocols tailored specifically for natural product-based nanoemulgels. By addressing these challenges, this study lays the groundwork for optimizing nanoemulgel formulations, ensuring reliable efficacy assessments, and enhancing consumer trust in natural-based skincare products. Keyword: Moisturizer, Nanoemulgel, Natural Product 
Development of Foundation Formulation From Eggshells as Anti UV Agent Putri, Salsa Davincy; Mardhiani, Yanni Dhiani; Adiyati Rum, Ira
Indonesian Journal of Pharmaceutics Vol 6, Issue 1, Jan - April 2024
Publisher : Universitas Padjadjaran (Unpad)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/idjp.v6i1.58955

Abstract

Foundation often contains anti-UV filters whether synthetic or natural. One of the natural ingredients that can be used as an anti-UV agent is eggshells because they contain calcium carbonate. This study aim to develop foundation as cosmetic preparation containing of duck eggshells and Moringa seed oil (Moringa oleifera Lam.)  for anti-UV agent. The combination of duck eggshell and moringa seed oil is carried out with the hypothesis can increase the ability of the preparation to protect the skin from exposure to solar radiation. Foundation preparation were made in 6 formulas with varying concentrations of duck eggshells and moringa seed oil. Evaluation of the preparations carried out included organoleptic test, homogeneity, pH, viscosity, spreadability, and color dispersion for 28 days at room temperature, freeze thaw stability test for 6 cycles, and anti-UV activity were carried out using spectrophotometry UV-Vis. The results of the evaluation were analyzed using One-Way ANOVA method. Based on the results of physical evaluation analysis, all formulas showed stable foundation preparations.  All preparations showed a non-irritative category after an irritation test on test animals (albino rabbits). Anti-UV activity with an average SPF value for F0 was 4,2±0,29 (minimal category), F1 was 18.75±1.41 (ultra category), F2 13.68±0.73 (maximum category), F3 14.00±0.46 (maximum category), F413.02±0.47 (maximum category), and F5 18.14±0.31 (ultra category). Keywords: Eggshells, moringa seed oil, cosmetic foundation, SPF

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