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All Journal Kreasi: Jurnal Inovasi dan Pengabdian Kepada Masyaraka Exacta: Journal of Pure and Fundamental Research
Mia Audina
Politeknik Negeri Sambas
Environmental Science Law, Crime, Criminology & Criminal Justice Social Sciences

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Penguatan Literasi Sains dan Karakter Peduli Lingkungan melalui Pendampingan Media Pembelajaran Berbasis Biodiversitas Lokal Mahwar Qurbaniah; Mia Audina; Ahmad Faisal Amri; Nuri Dewi Muldayanti; Arif Didik Kurniawan
Kreasi: Jurnal Inovasi dan Pengabdian kepada Masyarakat Vol. 6 No. 1 (2026): April
Publisher : BALE LITERASI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58218/kreasi.v6i1.3419

Abstract

This community service program aimed to strengthen students’ scientific literacy and environmental awareness through biodiversity-based learning assistance at SMP IT Az-Zahira Khatulistiwa. The identified problems included the limited use of the school environment as a contextual learning resource, the lack of exploratory learning activities in science classes, and the limited utilization of local potential based learning media. The program employed a participatory experiential learning approach consisting of needs assessment, local flora exploration, learning media assistance, contextual learning implementation, and evaluation. Teachers and students actively participated in observing local plants, identifying plant characteristics, compiling flora identification sheets, and developing simple biodiversity-based learning media. The results demonstrated improvements in students’ scientific observation skills, plant classification abilities, collaborative learning, and environmental awareness. The program also produced local biodiversity learning media and an environmental education corner utilized as a sustainable science learning resource. Overall, the program contributed to the development of contextual, participatory, and environmentally oriented science learning.
Microbial Resistance Evolution: Theoretical Perspectives on Genetic Mutation and Environmental Pressure Deford Cristy Birahy; Mia Audina; Anjela Karunia Amalia
Exacta: Journal of Pure and Fundamental Research Vol. 1 No. 1 (2026): March: Exacta: Journal of Pure and Fundamental Research
Publisher : CV SCRIPTA INTELEKTUAL MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.65310/smcw0074

Abstract

Microbial resistance has traditionally been interpreted through reductionist frameworks emphasizing isolated genetic mutations or clinical antibiotic exposure. This study advances a non-empirical theoretical investigation grounded in integrative conceptual modeling to reconceptualize resistance evolution as a cross-scale, eco-evolutionary phenomenon. A multi-scale analytical framework was constructed to synthesize stochastic mutation supply, horizontal gene transfer, metabolic rewiring, proteostasis regulation, environmental heterogeneity, and anthropogenic chemical pressures into a unified systems architecture. Structured theoretical synthesis and boundary-condition analysis were employed to test internal coherence and cross-context stability. The model demonstrates that resistance emerges as a metastable adaptive state maintained by feedback loops linking molecular mechanisms, community-level interactions, and physicochemical gradients across environmental compartments. Disinfectant exposure, nutrient enrichment, wastewater co-selection, and climate variability were incorporated as dynamic modulators of selective intensity. The resulting framework exhibits explanatory integration, cross-scale generalizability, and predictive plausibility under fluctuating selective regimes. By situating microbial resistance within interconnected ecological and evolutionary systems, this study provides a robust theoretical platform capable of guiding future simulation-based modeling and empirical corroboration within the One Health continuum.
Co-Authors Ahmad Faisal Amri Anjela Karunia Amalia Arif Didik Kurniawan Deford Cristy Birahy Muldayanti, Nuri Dewi Qurbaniah, Mahwar