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All Journal Jurnal Riset Hesti Medan Akper Kesdam I/BB Medan Jurnal Keperawatan dan Fisioterapi (JKF) JURNAL KEBIDANAN KESTRA (JKK) Jurnal Kesmas dan Gizi (JKG) JURNAL FARMASIMED (JFM) Jurnal Kesmas Prima Indonesia JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan NURSING UPDATE JURNAL ILMIAH ILMU KEPERAWATAN Best Journal (Biology Education, Sains and Technology) Jurnal Prima Medika Sains Jurnal Aisyah : Jurnal Ilmu Kesehatan Indonesian Journal of Global Health research JURNAL PENELITIAN KEBIDANAN & KESPRO Jurnal Ilmiah Wahana Pendidikan Jurnal Antara Abdimas Kebidanan Jurnal Pengmas Kestra (JPK)
Lubis, Basyariah
Institut Kesehatan Medistra Lubuk Pakam
Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : JURNAL FARMASIMED (JFM)

 1 
ANALIYSIS OF RHODAMINE B DYESTUFFS ON LIPTINT USING UV-VIS SPECTROPHOTOMETRY METHOD wulandari, suci; Rahma, Amalia Nur; Wahyuni, Siti; Lubis, Basyariah
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1295

Abstract

Background : Rhodamine B is a synthetic dye that is generally used as a dye for paper, textiles or inks. The use of Rhodamine B is certainly very dangerous for health. Rhodamine B if used directly on the human body will cause irritation of the respiratory tract and can cause cancer and liver damage. Although there are negative impacts, the use of these dyes is still often done, especially for food and cosmetic products. Purpose : This research was conducted to identify and determine levels of Rhodamine B in liptint traded in Lubuk Pakam sub-District. Method : Qualitative analysis of Rhodamine B was carried out by Thin Layer Chromatography (TLC) using ethylacetate-methanol-ammonia (45:25:30), while quantitative analysis for assay was carried out using UV-VIS Spectrophotometry at a wavelength of 545 nm. The linear calibration curve in the range of 1 - 5 ?g /ml resulted in the regression equation y = 0.0091x - 0.009. Results : The results of the qualitative analysis showed that the three samples containing Rhodamine B with each Rf value of 0.87 cm (sample A), 0.96 cm (sample B), 0.98 cm (sample C) and quantitatively the levels for sample A were known is 13,144 mg/g, sample B is 27,704 mg/g and sample C is 20,386 mg/g. Conclusion : From this research, it is known that there is still the use of Rhodamine B as a dye in liptint traded in Lubuk Pakam sub-district
THE IMPLEMENTATION OF PHARMACEUTICAL SERVICE STANDARDS IN PHARMACIES OF ROKAN HULU DISTRICT Situmorang, Manotar; Saman; Basyariah Lubis
Jurnal FARMASIMED (JFM) Vol 6 No 1 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v6i1.1820

Abstract

Currently, pharmaceutical services have experienced a lot of development, which initially used to focus on drug management, but have now turned into drug and clinical pharmacy services aimed at raising the standard of living of patients. Pharmaceutical applications are carried out according to pharmaceutical service standards in pharmacies which serve as the basis for providing services. Minister of Health Number. 73 of 2016 is a benchmark that is always guided by pharmaceutical staff in providing services. In this research, qualitative research was chosen which is descriptive quantitative through a cross sectional approach. The sample is determined using the Non-Probability Sampling technique, namely the Total Sampling type where the total population is determined as a sample. Where the number of samples selected amounted to 25 people. Research data must be in-depth, clear, and specific through in-depth interviews and observations. Data analysis was performed on variables through univariate analysis and bivariate analysis using the Chi Square test with a 95% confidence level. Aspects of infrastructure, Management of Pharmaceutical Supplies and Health Supplies, and administration have a significant relationship to pharmaceutical services at pharmacies in Rokan Hulu district with each sequential p-value being 0.002; 0.003; and 0.003. In improving services in accordance with Permenkes Number. 73 of 2016, it requires qualified facilities and infrastructure, good health management and provision, as well as complete administration.
Evaluation of the Effectiveness of Ethanol Extract of (Acalypha indica L.) Leaves as a Treatment for Gastric Ulcers in Male Rattus norvegicus Rats Wulandari, Suci; Hasni Yaturramadhan Harahap; Rinanda Desela Br Tambunan; Basyariah Lubis
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/bvmsms48

Abstract

Acalypha indica L., commonly known as Indian copperleaf, is a wild medicinal plant typically found along roadsides and in gardens. Its leaves contain various bioactive compounds, including saponins, flavonoids, alkaloids, and tannins. Traditionally, the plant has been used for its anti-inflammatory, antibacterial, antifungal, and antioxidant properties, which help combat oxidative stress caused by free radicals. This study aimed to evaluate the effectiveness of ethanol extract of Acalypha indica L. leaves in treating gastric ulcers in male Wistar rats (Rattus norvegicus). This research was a true experimental study involving the extraction of Acalypha indica L. leaves using ethanol, preparation of the extract suspension, and induction of gastric ulcers in rats using aspirin at a dose of 800 mg/kg body weight (BW) administered orally. A total of 30 male Rattus norvegicus rats were divided into six groups. Three control groups is Ulcer control, Negative control, Positive control. Three treatment groups receiving ethanol extract of Acalypha indica leaves (EEAIL) at doses of: EEDAA 50 mg/kgBB, EEDAA100 mg/kg BB, EEDAA 200 mg/kgBB. Ulcer induction was carried out daily until surgical examination was performed on days 4, 9, and 14. Macroscopic observations of the stomach were conducted to assess the number of ulcers and ulcer scores. Statistical analysis was performed using one-way ANOVA, followed by Tukey’s post hoc test to determine significant differences between groups. Macroscopic examination showed that the ethanol extract of Acalypha indica leaves (EEAIL) reduced the number of gastric ulcers. Complete healing of ulcers was observed in the positive control group, as well as in the groups receiving EEAIL at 200 mg/kg BW and 100 mg/kg BW, by day 14. In contrast, the 50 mg/kg BW group and the ulcer control group showed no signs of healing by the end of the observation period. The most effective dose was 200 mg/kg BW, demonstrating the highest capacity to reduce the number of gastric ulcers.
Co-Authors Achmad Rifai Achmad Rifai ACHMAD RIFAI Adela Sari Lubis Aritonang, Esra Puspita Barita Barita Br Bangun, Sri Melda Br Girsang, Desri Meriahta Budi Aswin David Ginting Delita Panjaitan Dwi Handayani Fadlilah Widyaningsih Felix Kasim Harahap, Mutiara Hatni Hasni Yaturramadhan Harahap Herlina H Ika Nur Saputri Irma Nurianti Irmayani Irmayani Iskandar Markus Iskandar Markus Iskandar Markus Sembiring Jansfianti, Mira Juliandi Harahap Jurpia Yasara Koropit, Sesca Vanda Latifah Hanim Lubis, Samran Maswan Daulay Munthe, Novita Br Ginting Nur Indrawaty Lipoeto Nurmala Sari Nursaputri, Ika Purwati, Yunita Putri Damayanti Damanik Rahma, Amalia Nur Rahmad Gurusinga Rahmad Gurusinga Raini Panjaitan Raisha Octavariny Rinanda Desela Br Tambunan Riri Safitri Rismauli Situmorang Rizka Wulandari Ronny Ajartha Ronny Ajharta Rosfita Rasyid Rotua Sumihar Sitorus Rozi Sastra Purna Safrida Nuzul Hayati Saiful Batubara Saman Sinambela, Ika Mariani Siregar, GF Gustina Siti Sarah Bintang Siti Wahyuni Situmorang, Manotar Sri Melda Bangun Sri Melda Br Bangun Sri Melda Br. Bangun Sri Melda Br.Bangun Sri Wahyuni Sri Wulan Srimelda Br Bangun Suci Wulandari Surio Retno Susi, Susilawati Tioman Deliana Titin Novayanti Dey Wasliati, Balqis Widyaningsih, Fadlilah Yuni Adelia