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Journal : Jurnal Gizi Klinik Indonesia

Fortifikasi besi dan prebiotik pada kukis terhadap histologi usus tikus anemia Rafika, Muhana; Lestari, Lily Arsanti; Helmyati, Siti
Jurnal Gizi Klinik Indonesia Vol 19, No 4 (2023): April
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.42606

Abstract

Iron dan prebiotic fortification in cookies towards intestine histology anemia ratsBackground: Anemia can also cause damage to small intestinal villous cells. Iron fortification can be an alternative prevention of anemia. Prebiotic additives can reduce the effects of fortification and improve intestinal villous.Objective: The study aims to determine the effect of breadfruit and soybean-based cookies with prebiotic and iron fortification on the small intestine's histology, especially the intestinal villous's height and width.Methods: Experimental study with posttest control group design with a total sample of 48 rats. Rats were divided into eight groups, given breadfruit and soybean-based cookies with the addition of FOS and NaFeEDTA (K1), FOS and FeSO4 (K2), FOS (K3), FeSO4 (K4), NaFeEDTA (K5), without fortification (K6). In addition, K- is a healthy mouse with standard feed, and K + is an anemia mouse. Anemia induction is for two weeks, and intervention is for 28 days. Intestinal histology was observed using an optilab microscope and measured using ImageRaster 4.0.5.Results: There were no significant differences in duodenum villous height, jejunum villous height, and ileum villous width (p>0.05). However, there were significant differences (p <0.05) for duodenum villous width (K- and K3), jejunum villous width (K1 and K4) and ileum villous height (K1, K2 and K +).Conclusions: Giving breadfruit-based and soybeans with prebiotic and iron fortification can increase the height and width of small intestinal villi.
Optimasi pemenuhan zat gizi dan penyusunan menu untuk pencegahan kekurangan energi kronik pada wanita prakonsepsi Putri, Febriani; Kandarina, BJ. Istiti; Helmyati, Siti
Jurnal Gizi Klinik Indonesia Vol 20, No 3 (2024): Januari
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.73203

Abstract

Optimization of nutritional fulfillment and menu recommendations to prevent chronic energy deficiency in preconception womenBackground: Chronic energy deficiency (CED) is a nutritional problem in Indonesia that occurs in women of childbearing age (WCA). This made them the group that must be given attention, especially nutrition, because they will be mothers. The Special Region of Yogyakarta is one province with a proportion of pregnant women with CED above the national average. Dietary intake patterns must be designed to comply with nutritional recommendations while maintaining the intake of specific local and cultural foods.Objective: This study aimed to analyze CED status, food intake, and diversity and develop menu recommendations to prevent chronic energy deficiency using linear programming.Methods: This research used cross-sectional sampling with a quota sampling method, which obtained 110 respondents. The interview was conducted using a 24-hour recall form and SQ-FFQ, and a menu was created to prevent CED.Results: There was no difference in the average food intake against CED (p-value>0.05). There was no difference in average between food diversity (p-value=0,48) and daily expenditure (p-value=0,95). This study recommended a menu in 7 days with a minimum price and a variety of food.Conclusions: There was no average difference between food intake, food diversity, and food expenditure on CED. This menu recommendation can be used for respondents who suffer from CED and those who do not suffer from CED by considering the nutrients that have been achieved.
Kepatuhan minum obat hipoglikemik oral dan indeks massa tubuh terhadap kadar gula darah pada pasien diabetes melitus tipe 2 Wathani, Ika Hanna Nurul; Purba, Martalena Br; Helmyati, Siti
Jurnal Gizi Klinik Indonesia Vol 21, No 2 (2024): Oktober
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.91474

Abstract

Adherence to oral hypoglycemic drugs and body mass index on blood sugar level in patients with type 2 diabetes mellitusBackground: Type 2 Diabetes mellitus (T2DM) is the most common diabetes and more than 95% of people with diabetes have type 2 diabetes mellitus. The Special Region of Yogyakarta is the province with the second highest prevalence of DM in Indonesia. One of the obstacles that often occurs in patients with T2DM who require long-term therapy is non-adherence to treatment and lack of attention to nutritional status which has an impact on the blood sugar levels of patients with T2DM.Objective: This study aims to analyze the relationship between the level of adherence to oral hypoglycemic drugs and body mass index on blood sugar levels in patients with T2DM in the working area of Minggir Health Center. Methods: A cross-sectional study design with purposive sampling technique. Obtained a total of 96 patient with T2DM in October 2023 who had met the inclusion and exclusion criteria, including using oral hypoglycemic drugs for at least 6 months and not using insulin therapy. Data on adherence to oral hypoglycemic drugs were obtained using the MARS-5 questionnaire, data on blood sugar levels used fasting blood sugar levels, and body mass index values were obtained from measuring height and weight. The analysis used the Chi-square test (p-value<0,05).Results: The majority of respondents had a high level of adherence to oral hypoglycemic drugs (56,3%), were overweight (79,2%), and had poor blood sugar levels (55,2%). There was no significant relationship between the level of adherence to oral hypoglycemic drugs and blood sugar levels ((P-value=0,776; PR=0,912). A non-significant relationship was also found between body mass index and blood sugar levels ((P-value=1,000; PR=1,005).Conclusions: The level of adherence to oral hypoglycemic drugs and body mass index were not significantly associated with blood sugar levels in patients with T2DM