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Journal : INDONESIAN MIDWIFERY HEALTH AND SCIENCES JOURNAL

BINAHONG [Anredera cordifolia (Tenore) Steenis] LEAF INFUSA FOR SUTURE WOUND INFECTION CONVALESCENCE Baso, Siti Nur Azizah Sucitra; Azizah, Nurul; Rosyidah, Rafhani; Rinata, Evi
Indonesian Midwifery and Health Sciences Journal Vol. 7 No. 4 (2023): Indonesian Midwifery and Health Sciences Journal, October 2023
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v7i4.2023.302-316

Abstract

Background: Postpartum infections are the top 4 main causes of the high maternal mortality rate in Indonesia at 2022 of 183 per 100,000 live births. Efforts to prevent complications due to infection of puerperal suture wounds with pharmacological therapy using antibiotics and antiseptics, as well as non-pharmacological ones using plant extracts. Binahong is believed to contain flavonoids, terpenoids, saponins, tannins, essential oils, and alkaloids, which are especially useful in healing wound infections. The aim of the study was to determine the effectiveness of infusion of binahong leaves (Anredera cordifolia (Tenore) Steenis) on the healing of suture wound infections in rats (Rattus norvegicus) experimental animals. Method: The research method was a true-experimental posttest only control group design, the study was conducted from June to August 2023 at the Microbiology and Pharmacology Laboratory of Muhammadiyah Sidoarjo University, the research variables were binahong leaf infusion and healing of suture infection, assessment and data collection using the REEDA scale instrument, statistical analysis with the one-way ANOVA, and post-hoc follow-up tests. Result: The results showed p <0.05, so there was a significant effect of giving binahong leaf infusion on the healing of suture wound infections. In terms of the difference in the mean value and the results of the post-hoc significant difference test, it appears that the 5% binahong leaf infusion group showed the most effective results in healing suture wound infections and was significantly different from the negative control group with less effective healing of suture infections. Conclusion : This is in line with research that states that the group given a 5% concentration of binahong extract was more effective than the group with a higher concentration. Thus, administration of a 5% concentration of binahong leaf infusion can be an alternative for healing suture wound infections due to the important content in it in the form of flavonoids, terpenoids, saponins, tannins, essential oils, and alkaloids. Further research is needed with lower concentrations of binahong leaf infusion to find out the minimum concentration that can have a good effect on the convalescence of suture wound infections.
CARICA PAPAYA L. WITH SUTURE WOUND HEALING IN MICE EXPERIMENTAL ANIMALS Istiqomah , Dani; Azizah, Nurul; Purwanti, Yanik; Rinata, Evi
Indonesian Midwifery and Health Sciences Journal Vol. 7 No. 4 (2023): Indonesian Midwifery and Health Sciences Journal, October 2023
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v7i4.2023.285-292

Abstract

Background: Stitches are a condition in which skin tissue damage results from incisions or surgery and trauma. Carica Papaya Linn contains flavonoids which are efficacious as anti-inflammatory or antiseptic in inhibiting bacterial growth. Carica Papaya Linn is effective in repairing cells damaged by free radicals. The purpose of this study was to see the effectiveness of papaya leaf extract (Carica Papaya Linn) against stitches. Method: This research was quantitative research with a True Experimental design with the one group post-test method using the REEDA scale assessment. The population in this study were mice (Mus Musculus) which were divided into 5 groups, control group, nebacetin group, 5% test group, 10% test group and 15% test group. Research was conducted in the Lab. Medical Laboratory Technology at Muhammadiyah University of Sidoarjo and for making extracts from the Faculty of Mathematics and Natural Sciences, Surabaya State University. Data was collected and then the results were analysed using the One Way ANOVA statistical test. Result: The results of the statistical test showed a value of P = 0.000 in the 7th day group, which means there was a difference in each group of mice and the mean results showed the lowest result was 0.2 in the 15% extract which stated the best wound healing. Conclusion : The conclusion of the study was that there was an effect of giving papaya leaf extract (Carica Papaya L.) on wound healing in experimental mice.
Co-Authors Agmar, Alfisyar Agus Muji Santoso Agus Salim Agus Syahrani Agus Syahrani Agustiningrum, Rita Aini, Latifatul Alia Bihrajihant Raya Alia Bihrajihant Raya Anang Wahid M.Diah Andayani, Gita Ayu Andayani, Gita Ayu Andika Aliviameita Anggraeni Dyah S Anggraeni Dyah Sulistiowati Anggraini, Sekarlita Normaulida Arifin Dwi Saputro Azhari, Tontowi Azizah, Nurul Bachtiar, Willy Baso, Siti Nur Azizah Sucitra Cholifah , Siti Dewi Izzatus Tsamroh Dewi Komala Sari Dian Delta Dina Trikumalasari Dira Nadila Dwi Ayu Fitriani Effy Wardati Maryam Finda Meyditia Finda Meyditia Hamdi, Hafmi Putri Syahilda Hendy Setiawan Hendy Setiawan Herlina, Lien Hesti Widowati Iflahah, Dini Ika Ratna Indra Astutik Indahyanti , Uce Isna Fitria Agustina Istiqomah , Dani Khasanah, Nur Riska Alfiyah Livia Nur Azzah M. Suryawinata M. Suryawinata Miftahul Mushlih Muntadir, Lila Nanang Wahyudin Nanang Wahyudin Normaulida Anggraini, sekarlita NURUL AZIZAH Okky Elvira Novianti Paramitha Amelia Kusumawardani Pardede, Akim Manaor Hara Prigi Dewi Gita Aristanti Pungzup, Saowaros Puspitasari Puspitasari Puspitasari Puspitasari Puspitasari, Dini Ayu Putri Anjar Sari Putri Anjar Sari Putri, Arizki Amalia Qilmia Fanani Rafhani Rosyidah Rafhani Rosyidah rima siburian Rohman Dijaya Ronny Lesmana Rosyidah, Rafhani Rusdyati, Tutik Saidah, Sukma Nur Sari, Dwi Siska Mayang Sari, Putri Anjar Setyawardana, Eka Siska Aprilia Siti Zaenab Salim Soekarno, Krisjayanti Sri Mukhodim Faridah Hanum Tontowi Ashari Tsabita, Nabila Fatya Tutik Rusdyati Widowati, Hesty Widya Nurfadillah Widyarini Susilo Putri Willy Bachtiar Yanik Purwanti Yanik Purwanti Yanuar Dwi Prastyo Yasmin, Rizka Afifah Yonika