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Korelasi Glukosa Darah Puasa Pasien Diabetes Mellitus Tipe 2 yang Mengalami Obesitas Terhadap Kadar Amilase, Insulin dan Indeks Massa Tubuh Armal, Hadits Lissentiya; Annisa, Istiana; Nurcahya, Harini; Wiryanti, Ida
Anakes : Jurnal Ilmiah Analis Kesehatan Vol. 9 No. 1 (2023): Anakes: Jurnal Ilmiah Analis Kesehatan
Publisher : Universitas Mohammad Husni Thamrin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37012/anakes.v9i1.1404

Abstract

Diabetes Melitus (DM) menjadi salah satu penyebab kematian di dunia. Diabetes ditandai dengan tingginya kadar glukosa dalam darah, penyakit ini merupakan gangguan metabolik menahun akibat pankreas tidak memproduksi insulin yang cukup atau tubuh tidak dapat menggunakan insulin yang diproduksi secara efektif. Pankreas penderita DM tipe 2 belum rusak namun banyaknya penderita DM tipe 2 mengalami defisiensi insulin yang seharusnya tidak terjadi serta mengalami obesitas. Obesitas menjadi menyebabkan pankreatitis dan mempengaruhi insulin, pemeriksaan amilase pankreas yang bertujuan untuk mendiagnosa pankreatitis harus  dilakukan atau tepat dilakukan pada penderita DM tipe 2 yang mengalami defisiensi insulin. Penelitian ini bertujuan untuk melihat adanya hubungan antara Insulin, Amilase Pankreas, Indeks Massa Tubuh (IMT) dengan Glukosa Darah pada penderita DM Tipe 2. Penelitian ini merupakan penelitian cross sectional dengan pengambilan data sekunder sebanyak 213 pasien dengan riwayat DM Tipe 2. Data dianalisis dengan menggunakan SPSS 22.0 metode uji r dan uji regresi linear ganda. Hasil uji statistik yang diperoleh menunjukkan tidak terdapat hubungan yang signifikan antara Glukosa Darah Puasa dengan Amilase Pankreas (P>0,05),  terdapat hubungan yang signifikan antara Glukosa Darah Puasa dengan Kadar Insulin dan terdapat hubungan yang signifikan antara Glukosa Darah Puasa dengan Indeks Massa Tubuh (IMT) (P<0.05) pada penderita DM. Kata kunci         : Amilase, Diabetes Melitus Tipe 2, Glukosa Darah, IMT, Insulin 
Body mass index (BMI) and genetic factors that predispose associated with the incidence of hypertension Annisa, Istiana; Armal, Hadits Lissentiya; Mahardhika, Rian Bayu Santya
Malahayati International Journal of Nursing and Health Science Vol. 7 No. 7 (2024): Volume 7 Number 7
Publisher : Program Studi Ilmu Keperawatan-Fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/minh.v7i7.621

Abstract

Background: Hypertension is a very dangerous non-communicable disease (NCD) (Silent Killer). Body mass index (BMI) is a measuring tool for monitoring adult nutritional status related to a person's body weight. Genetic is the science that studies the inheritance of traits (heredity) in organism. Purpose: To determine the relationship between body mass index and genetic factors with hypertension. Method: A cross sectional approach, specially focusing on a descriptive quantitative. Participants were selected using purposive sampling and the Slovin formula, resulting in 100 participants from Girang Community Health Center. Univariate statistical analysis was conducted, including a chi square and multiple logistic regression. Results: Show a significance (p < 0.05) it means there is a relationship between body mass index and genetic with hypertension. The genetic variable that is most related to the incidence of hypertension is genetics with an odds ratio value of 3.441, meaning that respondents who have genetic hypertension have a 3.4 times chance of experiencing hypertension compared to respondents who do not have genetic hypertension. Meanwhile, the BMI variable has an odds ratio value of 1.903, meaning that respondents who have an abnormal BMI have a 1.9 times chance of experiencing hypertension compared to respondents who have a normal BMI. Conclusion: There is a relationship between Body Mass Index (BMI) and genetic with the incidence of hypertension.
Analysis Potential of Dadih as a Treatment for Diabetes Mellitus Based on Histopathological Images of the Pancreas in Mice (Mus musculus) L., Marlin Brigita; Armal, Hadits Lissentiya; Amien, A. Zakaria
Journal Of Health Science (Jurnal Ilmu Kesehatan) Vol 8 No 1 (2023): JOURNAL OF HEALTH SCIENCE (JURNAL ILMU KESEHATAN) (IN PRESS)
Publisher : Fakultas Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24929/jik.v8i1.2452

Abstract

The pathogenesis of Diabetes Mellitus is complex with one of the basic factors causing the disease is oxidative stress. Foods containing probiotics are reported to suppress oxidative stress. Probiotics containing L.acidophillus and L.casei are known to reduce oxidative stress and are antidiabetic. This happens because casei can reduce oxidative stress and suppress CD4 cells effectively, accompanied by a reduction of pro-inflammatory molecules so that it has an antioxidant effect but can also modulate the immune system. To see the role of dadih in this study, the research will be conducted using mice which are divided into three groups, namely the negative control group, the positive control group and the treatment group randomly. Blood sampling aims tomeasure blood glucose levels of mice using a glucometer. Histological observation of the mice's pancreatic organs was carried out to determine theantidiabetic effect of curd. The results of the One-Way ANOVA test showed that there was a significant difference in each treatment group (p=0.000). Giving curd can improve the pancreas of mice with diabetes mellitus seen from the histopathological picture that has pyknosis. The pathogenesis of Diabetes Mellitus is complex with one of the basic factors causing the disease is oxidative stress. Foods containing probiotics are reported
Kadar D-Dimer Sebagai Indikator Derajat Keparahan Pada Pasien Terkonfirmasi Covid-19 di RS. Permata Hati Tangerang Armal, Hadits Lissentiya; Bakti, Sukma; Annisa, Istiana
Journal of Medical Laboratory Research Vol. 2 No. 2 (2024): Journal of Medical Laboratory Research
Publisher : Politeknik Kesehatan Kementerian Kesehatan Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36743/jomlr.v2i2.732

Abstract

Terdapat beberapa pemeriksaan yang dapat dilakukan untuk mendiagnosa derajat keparahan infeksi COVID 19 diantaranya menggunakan pemeriksaan AGD, PT, APTT, D-dimer, NLR, ataupun Thorax Pa. Pemeriksaan D-dimer menjadi salah satu pemeriksaan yang sangat beperan penting dalam menentukan derajat keparahan pasien isolasi/ pasien yang infeksi COVID 19. D-dimer secara efektif memprediksi kematian di rumah sakit pada pasien COVID-19, yang mengindikasikan D-dimer dapat menjadi penanda awal dan bermanfaat untuk meningkatkan manajemen pasien COVID-19 Tujuan: penelitian ini adalah untuk mengetahui hubungan antara kadar d-dimer dan klasifikasi derajat keparahan pada pasien terkonfirmasi COVID-19 di RS. Permata Hati Tangerang. Metode: Jenis penelitian dengan pendekatan cross-sectional, populasi berjumlah 713 pasien, sampel berjumlah 256 responden, analisis dengan menggunakan uji chi-square. Hasil: Menunjukkan adanya hubungan antara kadar d-dimer dengan klasifikasi derajat keparahan pada pasien terkonfirmasi covid-19 di RS Permata Hati Tangerangkarena nilai p-value 0,000< (α= 0,05). Maka dapat disimpulkan bahwa Ha diterima dan Ho ditolak, jadi ada hubungan antara kadar d-dimer dengan klasifikasi derajat keparahan pada pasien terkonfirmasi covid-19 di RS Permata Hati Tangerang.
Pemberdayaan Remaja Putri dalam Upaya Pencegahan Stunting di Pondok Pesantren Wilayah Kecamatan Rangkasbitung Kabupaten Lebak Sutomo, Omo; Rusyanti, Siti; Armal, Hadits Lissentiya
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 8, No 2 (2025): Volume 8 No 2 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v8i2.18810

Abstract

ABSTRAK Stunting merupakan salah satu bentuk gizi kurang yang ditandai dengan indikator tinggi badan menurut umur; gangguan pertumbuhan yang menggambarkan tidak tercapainya potensi pertumbuhan sebagai akibat status kesehatan dan atau gizi yang tidak optimal, yang menggambarkan riwayat kekurangan gizi yang terjadi dalam jangka waktu yang lama.Stunting merupakan masalah kesehatan masyarakat yang sangat penting karena memiliki dampak yang besar terhadap kualitas sumber daya manusia pada satu generasi. WHO (2017) menyatakan bahwa kurang lebih terdapat 155 juta balita di dunia mengalami stunting. Di Indonesia, presentase balita dengan stunting dan savere stunting mengalami peningkatan sejak tahun 2007 s.d. 2013. Saat ini (2022) prevalansi stunting di Indonesia sebesar 21,6%. Di Banten sebesar 20%, dan di Kabupaten Lebak ada sebanyak 4.618 balita menderita stunting. Saat ini ada 4,08 juta santri termasuk didalamnya remaja putri/santriwati yang mengikuti pendidikan keagamaan (Islam) pondok pesantren Indonesia yang merupakan asset sumber daya manusia yang memerlukan perhatian setara dengan pendidikan formal lainnya. Di pondok pesantren La Tahzan dan AL Fafa tidak kurang 200 santri dari masing masing pondok pesantren yang memerlukan perhatian. Kenyataan menunjukkan bahwa para santri masih terbatas pemahamnnya tentang stunting dan cara pencegahannya. Tujuan Pengabdian kepada Masyarakat ini adalah untuk memberdayakan santri dalam upaya pecegahan stunting. Kegiatan pokok yang dilakukan meliputi edukasi tentang stunting dan perilaku hidup bersih dan sehat, pemberian tablet tambah darah serta pemasangan standing westapel. Hasil kegiatan menujukkan adanya peningkatan pengetahuan para remaja putri tentang stunting dan upaya pencegahannya dari skor 59,25 menjadi menjadi 8,5. Para santriwati mempraktikan perilaku baik upaya pencegahan seperti meminum tablet tambah darah 1 tablet setiap mingggu dan mencuci tangan dengan benar setiap selesai melakukan aktifitas di pondok pesantren. Perlu tindak lanjut dari kegiatan ini serta monitoring dan evaluasi secara berkala dari Puskesmas serta mengembangkannya di pondok pesantren yang lain. Kata Kunci: Pencegahan Stunting, Remaja Putri ABSTRACT Stunting is a form of malnutrition characterized by height indicators for age; growth disorders that describe the failure to achieve growth potential as a result of suboptimal health and/or nutritional status, which describes a history of malnutrition that has occurred over a long period of time. Stunting is a very important public health problem because it has a major impact on the quality of human resources in one generation. WHO (2017) stated that there are approximately 155 million toddlers in the world experiencing stunting. In Indonesia, the percentage of toddlers with stunting and savere stunting has increased since 2007 to 2013. Currently (2022) the prevalence of stunting in Indonesia is 21.6%. In Banten it is 20%, and in Lebak Regency there are 4,618 toddlers suffering from stunting. Currently there are 4.08 million students including female/female students who are taking religious education (Islam) at Indonesian Islamic boarding schools which are human resource assets that require equal attention to other formal education. At the La Tahzan and AL Fafa Islamic boarding schools, there are no less than 200 students from each Islamic boarding school who need attention. The reality shows that the students still have limited understanding of stunting and how to prevent it. The purpose of this Community Service is to empower students in efforts to prevent stunting. The main activities carried out include education about stunting and clean and healthy living behavior, providing iron tablets and installing standing water pipes. The results of the activity showed an increase in the knowledge of young women about stunting and efforts to prevent it from a score of 59.25 to 8.5. The female students practice good behavior in prevention efforts such as taking iron tablets 1 tablet every week and washing their hands properly after each activity at the Islamic boarding school. Follow-up is needed for this activity as well as regular monitoring and evaluation from the Health Center and developing it in other Islamic boarding schools Keywords: Stunting Prevention, Adolescent Girls
OPTIMAL COMBINATION OF TOLUENE AND CLOVE OIL (Syizigium aromaticum) IN THE PROCESS OF CLEARING THE PERMANENT PREPARATION PEDICULUS HUMANUS CAPITIS Ihsan, Bagus Muhammad; Liesvia, Vira; Armal, Hadits Lissentiya; Supriyanto, Supriyanto; Hanif, Muhammad Ifham
Media Penelitian dan Pengembangan Kesehatan Vol. 34 No. 2 (2024): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v34i2.2006

Abstract

Clearing is a vital process in microscopy, aimed at enhancing the transparency of tissue preparations for clearer observation of insect structures. Despite its effectiveness, Toluene poses safety concerns due to its explosive nature. Therefore, clove oil (Syzygium aromaticum) has been explored as a safer alternative. This study evaluates the quality of permanent preparations of Pediculus humanus capitis using both toluene and clove oil. Comparative tests were conducted, treating adult head lice specimens with each solvent for three repetitions. Permanent preparations were assessed for clarity, color quality, and morphological integrity. Results indicate a significant difference in quality between the two methods. Toluene yielded mainly poor-quality preparations, while clove oil resulted in a higher proportion of preparations of good quality. The Mann-Whitney test confirmed the significance of this difference (p = 0.002). This study highlights the efficacy of clove oil as a safer alternative to toluene in the clearing process, contributing to entomological practices and chemical safety.
Pooled Serum in House sebagai Bahan Kontrol untuk Pemantapan Mutu Internal Nuraeni, Hanny Siti; Armal, Hadits Lissentiya; Astriani, Ranti Dwi
Journal of Medical Laboratory Research Vol. 3 No. 1 (2025): Journal of Medical Laboratory Research
Publisher : Politeknik Kesehatan Kementerian Kesehatan Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36743/jomlr.v3i1.827

Abstract

One method used to carry out internal quality control at the analytical stage is to use control serum. . For some clinical laboratories, especially primary clinical laboratories where the number of clinical examinations is still small, the use of commercial control serum for quality control is not affordable because the cost is very expensive. Production of control materials from pooled blood serum can be used as an alternative to expensive production controls. The aim of this study was to find out whether serum collected at home can be used as a control material to carry out quality tests by determining its homogeneity and stability.The implementation process includes taking samples, sample from 48 person and then making pooled serum, examining pooled serum, homogeneity and stability tests, determining reference value ranges, and analyzing results. The combined serum that has been made is homogeneous and stable in the parameters of glucose and total cholesterol, while it is unstable in uric acid. The pooled serum value range for glucose is 49-86 mg/dL, total cholesterol 196-288 mg/dL and uric acid 1.36-3.70 mg/dL. The results of making pooled serum as a control material are declared homogeneous and stable in terms of glucose and total cholesterol parameters so that it can be used as quality control in daily activities. Suggestions for future researchers to add other parameters related to clinical chemistry examinations.