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All Journal Biotika: Jurnal Ilmiah Biologi Indonesian Journal of Biotechnology Agrokreatif Jurnal Ilmiah Pengabdian kepada Masyarakat BERITA BIOLOGI JC-T (Journal Cis-Trans): Jurnal Kimia dan Terapannya Jurnal Kimia Terapan Indonesia Chemistry Indonesian Journal of Chemical Research Martabe : Jurnal Pengabdian Kepada Masyarakat International Journal of Community Service Learning Walisongo Journal of Chemistry Molekul: Jurnal Ilmiah Kimia Journal of Educational Chemistry (JEC) Prosiding Konferensi Nasional PKM-CSR Molekul: Jurnal Ilmiah Kimia InSTEM
Tahya, Candra Yulius
Fakultas Ilmu Pendidikan, Program Studi Pendidikan Kimia, Universitas Pelita Harapan, Tangerang 15811, Banten, Indonesia.
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Nursing Physics Public Health Social Sciences Other

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Meningkatkan Minat Belajar Siswa Selama Pandemi Covid-19 Melalui Bimbingan Belajar Online Friska J. Purba; Kelly Sinaga; Debora Suryani Sitinjak; Candra Yulius Tahya; Karnelasatri
International Journal of Community Service Learning Vol. 6 No. 2 (2022): May 2022
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23887/ijcsl.v6i2.46068

Abstract

Pandemi COVID-19 telah merenggut kenyamanan siswa dalam mengikuti proses belajar mengajar. Kenyamanan belajar mengajar terenggut dikarenakan pemerintah menutup sekolah dan perguruan tinggi untuk menekan penyebaran virus COVID-19 yang kian merebak. Akibatnya, sistem pembelajaran harus diubah dari tatap muka (luring) menjadi tatap maya (daring). Pembelajaran jarak jauh (PJJ) yang dilakukan menyebabkan dampak negatif bagi siswa, salah satunya ialah penurunan minat dan semangat belajar. Hal ini terjadi dikarenakan kurangnya kemampuan guru dalam mengelola pembelajaran yang menarik dan bermakna. Berdasarkan permasalahan tersebut, maka Program Studi Pendidikan Kimia bekerja sama dengan jemaat GKPS Tangerang untuk membuat Pos Bimbingan Belajar Online Gratis yang diberi nama Pos Diakonia untuk membantu anak-anak, khususnya anak-anak jemaat GKPS dalam memahami materi sekolah dan meningkatkan minat dan semangat belajar siswa. Kegiatan ini berlangsung selama 8 minggu. Dari survei yang dilakukan kepada 83 tutee, hanya 44 yang memberikan respon. Dari respon tersebut didapatkan bahwa setelah mengikuti bimbel online hampir semua tutee merasakan peningkatan pemahaman, minat dan semangat belajar. Namun sayangnya, masih banyak juga tutee yang mengalami kesulitan dan minat belajar yang kurang bertumbuh.
Biosynthesis of Silver Microparticles Using Spondias Dulcis Fruit Peel Extract and Its Antibacterial Activity Girsang, Thereshia Margaretta; Purba, Elisabeth; Simamora, Adela Rosalia; Sihombing, Chatrina Yohana; Inabuy, Marchella; Tahya, Candra Yulius
Walisongo Journal of Chemistry Vol. 7 No. 2 (2024): Walisongo Journal of Chemistry
Publisher : Department of Chemistry Faculty of Science and Technology UIN Walisongo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/wjc.v7i2.22996

Abstract

In recent decades, the overuse and misuse of antibiotics, along with various social and economic factors, have accelerated the spread of antibiotic-resistant bacteria, including Klebsiella pneumoniae and Pseudomonas aeruginosa, both of which are Gram-negative pathogenic bacteria. Silver particles (AgPs) have garnered significant research interest over the years due to their diverse biological activities, particularly their antibacterial properties. The green synthesis method for silver particles involves synthesizing silver metal particles using natural materials derived from organisms such as plants, resulting in particles that are less harmful to human cells but highly toxic to pathogenic bacteria. Kedondong (Spondias dulcis) is a tropical fruit widely grown in South and Southeast Asia. The peels of this fruit often become organic waste with limited utility. To explore the potential of kedondong fruit peels, this study investigated the synthesis of silver particles using their extract. The ethanolic extract of kedondong fruit peels was analyzed using LC-MS/MS-QTOF, identifying 5 alkaloids, 21 flavonoids, and 17 terpenoid compounds. The total flavonoid and phenolic contents of the extract were determined to be 1.8918 and 12.8104 mg/g of extract, respectively. The silver particles synthesized in this study had an average size of 4641.97 micrometers and a zeta potential of 40.2 mV, as determined by PSA, and were confirmed as silver particles through P-XRD phase analysis. These silver particles exhibited strong antibacterial activity against P. aeruginosa, with an inhibition zone diameter of 19.43 mm, and moderate activity against K. pneumoniae, with an inhibition zone diameter of 11.50 mm, at a suspension concentration of 10 mg/mL. Notably, the P. aeruginosa strain used in this experiment was resistant to the antibiotic amoxicillin.
PENYULUHAN PENCEGAHAN DIABETES DAN KEGIATAN PERBAIKAN LAPANGAN OLAHRAGA WARGA DESA CIAKAR Yulius Tahya, Candra; Sinaga, Kelly; Purba, Friska; Iglecias Sihombing, Benedict
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 7, No 1 (2024): MARTABE : JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v7i1.356-361

Abstract

Diabetes merupakan penyakit yang ditandai dengan tingginya kadar gula dalam darah. Menurut data International Diabetes Federation, ada 230 ribu kematian akibat diabetes di tahun 2021 (Usia 20-79) dan diperkirakan terus meningkat setiap tahunnya. Dalam rangka mendukung pencegahan Diabetes dan mendukung Program Universitas Pelita Harapan untuk membina Desa-desa binaannya, khususnya dalam mengatasi masalah Penyakit Diabetes, maka Program Studi Pendidikan Kimia, bekerja sama dengan pengurus RT 004/RW 003 Desa Ciakar melaksanakan kegiatan Penyuluhan Pencegahan Diabetes bagi masyarakat pada 5 Maret 2023 dan kegiatan Perbaikan Lapangan Olah Raga Warga pada 25 Maret 2023. Kedua kegiatan ini diharapkan memberikan penyadaran dan penguatan pemahaman masyarakat tentang pencegahan dan deteksi dini penyakit diabetes, dan mendorong masyarakat untuk tetap giat berolah raga.
PENILAIAN KEDISIPLINAN DAN MINAT SISWA SMP PADA KEGIATAN EKSTRAKURIKULER SCIENCE CLUB MELALUI PRESENSI, KEAKTIFAN, DAN KETERLIBATANNYA Elfani Bermuli, Jessica; Puspitasari Izaak, Maya; Yulius Tahya, Candra
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 7, No 7 (2024): MARTABE : JURNAL PENGABDIAN MASYARAKAT
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v7i7.2637-2642

Abstract

Kegiatan ekstrakurikuler di salah satu sekolah di Tangerang dilakukan dalam bentuk Science Club. Kegiatan yang dilaksanakan bertujuan untuk mendalami dan mempraktikkan teori-teori sains (Biologi, Kimia dan Fisika) yang ada di kelas. Perbedaannya adalah praktikum yang dilakukan pada kelas Science Club merupakan praktikum yang tidak ada di textbook ataupun yang hampir tidak pernah dipraktikkan di sekolah. Siswa akan dinilai kedisiplinan dan minatnya pada kegiatan ekstrakurikuler. Keterlibatan menjadi tolak ukur untuk melihat minat siswa pada kegiatan science club ini. Program ekstrakurikuler Scince Club akan diajar dan didampingi oleh dosen-dosen dari Program Studi Pendidikan Biologi, Pendidikan Kimia dan Pendidikan Fisika serta enam orang mahasiswa sebagai asisten laboratorium. Kedisiplinan siswa SMP akan diukur berdasarkan presensi, keaktifan, dan keterlibatannya saat kegiatan berlangsung. Hasilnya adalah jumlah kehadiran siswa sebesar 80,83%. Kemudian dari 15 siswa, 12 siswa sangat aktif dan terlibat di dalam kegiatan sedangkan 3 orang lainnya perlu terus dibimbing untuk lebih terlibat dan aktif. Kegiatan Pengabdian kepada masyarakat ini direncanakan dilanjutkan pada semester berikutnya.
MOLECULAR DOCKING OF ANTIBACTERIAL ACTIVITY OF HEXAHYDRO-1,2,3-TRIAZINE DERIVATIVES Tahya, Candra Yulius; Irawati, Wahyu; Karnelasatri, Karnelasatri
Walisongo Journal of Chemistry Vol. 8 No. 2 (2025): Walisongo Journal of Chemistry
Publisher : Department of Chemistry Faculty of Science and Technology UIN Walisongo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/wjc.v8i2.26159

Abstract

Hexahydro-1,3,5-triazine and its derivatives have piqued the interest of numerous researchers due to its strong biological characteristics, which include antibacterial, antimalarial, fungicidal, antiviral, anticancer, antimicrobial, antiamoebic, anti-inflammatory, and antitubercular effects. The antibacterial activity test in this work was performed using molecular docking on 16 hexahydro-1,3,5-triazine derivative compounds and three drug molecule controls that were selected from the PDB database and targeted Penicillin binding protein 2A (PDB ID: 1VQQ). For docking, Pyrx v.1.1's AutodockVina integration was utilized. Docking utilizing the targeted docking strategy was performed using a specific gridbox that was chosen based on the location of significant amino acids and pharmacological controls. The drug potential of a chemical under test is described by the Pa (Probability to be Active) value. The results of the Pa value analysis showed that several hexahydro-1,3,5-triazine derivative compounds had a higher/better average Pa value compared to the control drugs Ceftaroline and Ceftobiprole. Based on the Lipinski rule of five, the analysis's findings indicated that six out of the sixteen test compounds had good drug-likeness features; however, according to Pfizer, every compound possessed these qualities. Nearly all of the drugs exhibited good pharmacokinetics, according to the ADMET study. According to molecular docking results, 13 out of 16 synthesized compounds generally exhibit a high affinity for the PBP2a target protein. Furthermore, four compounds had a higher affinity than the ceftobiprole drug control when compared to the three drug controls. Synthetic compounds, particularly compounds 7, 16, 15, and 1, have the potential to be used as antibacterial therapies, according to the results of QSAR, ADMET, and docking research.
The Antioxidant Test of Ecoenzymes from Various Fruit Peel Wastes Napitupulu, Happy Chelsy Betaria; Pangela, Misael Ivan; Telaumbanua, Hepy Terima; Lase, Joy Sisokhi Putra; Tahya, Candra Yulius; Ringo, Sisilya Siringo
Indonesian Journal of Chemical Research Vol 13 No 3 (2026): Edition for January 2026
Publisher : Jurusan Kimia, Fakultas Sains dan Teknologi, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/ijcr.2026.13-hap

Abstract

Indonesia is a country with a large population and rapid industrial growth, facing serious challenges related to waste management. Waste is the remains produced by human activities. One interesting solution to handle the problem is the production of ecoenzymes through the fermentation process of natural organic waste materials. Ecoenzymes are biotechnology products that produce various types of enzymes and organic chemicals that are useful for various applications. Apart from that, laboratory tests also revealed the presence of antioxidant activity in these ecoenzymes, for Ecoenzyme A (IC50 = 13735.9 μg/mL) about 0.4 mL of ecoenzyme solution could inhibit 50% of radical activity, and for Ecoenzyme B (IC50 = 12029.4 μg/mL) about 0.3 mL solution could inhibit 50% of radical activity, and for Ecoenzyme C (IC50 = 15765.1 μg /mL) about 0.4 mL ecoenzyme could inhibit 50% of radical activity, which, although categorized as weak, is because the volume of ecoenzyme produced is very much greater (2 L) than the volume used for antioxidant testing, this product is much more economical and has enormous potential to be developed into cosmetic ingredients and other industrial products.
Developing Science Process Skills in Science Club Activities at a Private School in South Tangerang Jessica Elfani Bermuli; Candra Yulius Tahya; Maya Puspitasari Izaak
Jurnal Inovasi Sains dan Teknologi Untuk Masyarakat Vol. 3 No. 2 (2025): November
Publisher : Faculty of Mathematics and Natural Sciences, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/instem.v3i2.7

Abstract

This Community Service Program (PkM) aims to develop junior high school students’ science process skills (SPS) through Science Club activities at a private school in South Tangerang, Indonesia. This activity is a collaboration between the Faculty of Education at Universitas Pelita Harapan and the private school located in the BSD area of Tangerang. Community Service Activities were held every Tuesday from January 24 to April 2024, from 3:00 p.m. to 4:30 p.m. Western Indonesian Time, and focused on assessing junior high school students' science process skills through their attendance, activities, and involvement during practical work. The method used is direct experimental learning in the laboratory to enhance students’ scientific skills. The Science Club is designed as an extracurricular platform that allows students to explore and practice concepts in Biology, Chemistry, and Physics beyond textbook learning. The program was conducted over eight sessions, where students carried out experiments on topics that are not commonly practiced in schools but can be implemented simply in the laboratory using easily accessible tools and materials. Evaluation using an SPS rubric showed positive results: 80.83% attendance and 73.33% of students achieved an A grade. In addition to improving scientific skills, the program also contributed to students’ educational, health, environmental, and psychological aspects. These results indicate the potential sustainability of the program to support holistic learning based on biblical perspectives.
Co-Authors Adila, Mahda Uli Benedict Iglecias Sihombing Debora Sitinjak Elen Tiwery Elfani Bermuli, Jessica Elisabeth Wulan Kainde Friska J. Purba Friska Purba Gaspersz, Nelson Girsang, Thereshia Margaretta Greisnaningsi Greisnaningsi Hardy, Junius Iglecias Sihombing, Benedict Inabuy, Marchella Jessica Elfani Bermuli Kainama, Healthy Karnelasatri Karnelasatri Karnelasatri, . Kelly Sinaga Kelly Sinaga Lase, Joy Sisokhi Putra Maya Puspitasari Izaak Mega Gracelia Monaten Melanie Cornelia Melanie Cornelia, Melanie Muhammad Ikhsan Taipabu Munthe, Sri Wahyu Ningsih Napitupulu, Happy Chelsy Betaria Pangela, Misael Ivan Purba, Elisabeth Purba, Friska Purba, Friska Juliana Ringo, Sisilya Siringo Sihombing, Chatrina Yohana Simamora, Adela Rosalia sinaga, kelly Sitinjak, Debora Suryani Tagor M Siregar Tagor M. Siregar Tahya, Kartika Telaumbanua, Hepy Terima Tryani K. Junita Lumbantoruan WAHYU IRAWATI Wahyu Irawati