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All Journal Biotika: Jurnal Ilmiah Biologi Indonesian Journal of Biotechnology Agrokreatif Jurnal Ilmiah Pengabdian kepada Masyarakat BERITA BIOLOGI JC-T (Journal Cis-Trans): Jurnal Kimia dan Terapannya Jurnal Kimia Terapan Indonesia Chemistry Indonesian Journal of Chemical Research Martabe : Jurnal Pengabdian Kepada Masyarakat International Journal of Community Service Learning Walisongo Journal of Chemistry Molekul: Jurnal Ilmiah Kimia Journal of Educational Chemistry (JEC) Prosiding Konferensi Nasional PKM-CSR Molekul: Jurnal Ilmiah Kimia
Tahya, Candra Yulius
Fakultas Ilmu Pendidikan, Program Studi Pendidikan Kimia, Universitas Pelita Harapan, Tangerang 15811, Banten, Indonesia.
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Nursing Public Health Social Sciences

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Pantoea agglomerans, Klebsiella pneumoniae, and Shigella flexneri isolated from the Cisadane River as multiresistant bacteria to copper and dyes Wahyu Irawati; Candra Yulius Tahya; Greisnaningsi Greisnaningsi
Indonesian Journal of Biotechnology Vol 27, No 4 (2022)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijbiotech.66103

Abstract

Copper pollution in Cisadane is a serious environmental issue that needs to be resolved immediately due to its negative impacts on river ecosystems. Bioremediation utilising indigenous bacteria offers excellent potential to restore copper‐contaminated river water. This study aimed to obtain indigenous copper‐resistant bacteria isolated from the Cisadane River as copper bioremediation agents. Bacteria from Cisadane River water samples were isolated by the spread plate method on Luria Bertani medium containing 3 mM CuSO4. Resistance was determined based on the minimum inhibitory concentration value, while copper concentration was measured using an atomic absorption spec‐ trophotometer. The results presented a total of 13 bacterial isolates with a minimum inhibitory concentration of up to 8 mM CuSO4. Sequence alignment analysis was performed on three selected copper‐resistant bacteria, i.e. isolate IrCis1, IrCis4 and IrCis13, which were identified as Pantoea agglomerans, Klebsiella pneumoniae and Shigella flexneri based on 16S rRNA, respectively. Each isolate accumulated copper at 1.19 mg, 1.34 mg and 0.92 mg/g DW of cells, with copper biosorption potentials of 73.74%, 70.17% and 67.73%, respectively. In conclusion, P. agglomerans strain IrCis1, K. pneu‐ moniae strain IrCis4 and S. flexneri strain IrCis5 isolated from the Cisadane River can be used as copper bioremediation agents.
Adsorption of Copper Ion from Acidic Wastewater by Local Natural Zeolite Candra Yulius Tahya; Melanie Cornelia; Tagor M Siregar; Muhammad Ikhsan Taipabu
Walisongo Journal of Chemistry Vol 5, No 2 (2022): Walisongo Journal of Chemistry
Publisher : Department of Chemistry Faculty of Science and Technology Walisongo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/wjc.v5i2.11714

Abstract

Natural zeolites are available in Indonesia in very large quantities and are available in the market at very affordable prices. The use of zeolite has developed in various fields of industry, water treatment and wastewater treatment. The study on the ability of local natural zeolite to adsorb copper from acidic wastewater from a laboratory in Tangerang has been conducted.  XRD data show that the local natural zeolite consists of mordenite as main mineral and quartz as an accessory mineral. Acid activation of zeolite with HCl 3 M could remove quartz impurities from natural zeolite based on XRD data. Mordenite is one of the most abundant zeolite minerals and commercially used for many purposes including adsorbents, catalyst, fertilizer, and gas separation. The crystallinity of mordenite decreases throughout the process of acid activation and calcination. The calcined zeolite has better copper adsorption ability compared to local natural zeolite without any treatment. The optimum copper adsorption percentage is 14.554% at solution pH of 0.3 by using 10 grams of calcined zeolite in 200 mL of wastewater solution.
PENYULUHAN PENCEGAHAN PENYAKIT MENULAR DAN BAKTI SOSIAL PEMBERSIHAN SALURAN AIR DI DESA CIAKAR RT 004/ RW 003, KECAMATAN PANONGAN, KABUPATEN TANGERANG Candra Yulius Tahya; Kelly Sinaga; Friska Purba; Benedict Iglecias Sihombing
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 6, No 5 (2023): martabe : jurnal pengabdian kepada masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v6i5.1788-1795

Abstract

Dalam upaya mendukung Program Universitas Pelita Harapan untuk membina Desa-desa binaannya, termasuk Desa Ciakar, khususnya dalam megatasi masalah kesehatan masyrakat, Program Studi Pendidikan Kimia, bekerja sama dengan pengurus RT 004/RW 003 melaksanakan kegiatan Penyuluhan Penyakit Menular pada 5 Maret 2023 dan kegiatan Bakti Sosial pada 18 Maret 2023. Kedua kegiatan ini akan menjadi pendorong semangat dan penguatan pemahaman masyarakat tentang menjaga kebersihan lingkungan dan mencegah penyebaran berbagai penyakit menular di lingkungannya. Pengurus RT pun juga berkomitmen dengan bantuan beberapa sarana kebersihan yang diberikan UPH, akan tetap menjalankan bakti sosial-bakti sosial selanjutnya sehingga kebersihan dan kesehatan warga bisa semakin ditingkatkan.
Chemical Profiling and Histamine Inhibitory Activity Assessment of Merremia Vitifolia and Bidens Pilosa Extracts Candra Yulius Tahya; Karnelasatri Karnelasatri; Nelson Gaspersz
Molekul Vol 18 No 1 (2023)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2023.18.1.6833

Abstract

There are two species of plant that grow flourishing all around Indonesia including in Banten and West Java which are Merremia vitifolia and Bidens pilosa. In this study we evaluate how these plants could be potentially used as natural preserver of fish product especially Auxis thazard, to inhibit the histamine formation, and to find out how this activity correlates to the substances in polar extract of B. pilosa flowers and M. vitifolia leaves. Liquid chromatography with tandem mass spectrometry (LC-MS/MS) and gas chromatography-mass spectrometry (GC-MS) were used to identify the substances of the plant’s part extracts. There are 27 chemicals in M. vitifolia extract and 14 chemicals in B. pilosa extract that have been detected. A triglyceride has been detected, isolated, and characterized by FTIR, 1H-NMR and 13C-NMR from n-hexane extract of M. vitifolia supported by LC-MS/MS data. Histamine formation in fish was determined after 30 min treatment with 4-hydroxybenzoic acid solution is around 40 – 51 mg / 100 g of fish, while treatment with M. vitifolia and Bidens pilosa extracts were less than 10 mg / 100 g of fish. This is the indication of high potential of both extract as preserver of fish products. Many of the identified substances have bioactivity like antimicrobial, anticancer, anti-inflammatory, antioxidant, and more, which influence the extracts’ ability to inhibit the formation of histamine in fish.
PENYULUHAN PENCEGAHAN DIABETES DAN KEGIATAN PERBAIKAN LAPANGAN OLAHRAGA WARGA DESA CIAKAR Candra Yulius Tahya; Kelly Sinaga; Friska Purba; Benedict Iglecias Sihombing
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 7, No 1 (2024): MARTABE : JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v7i1.356-361

Abstract

Diabetes merupakan penyakit yang ditandai dengan tingginya kadar gula dalam darah. Menurut data International Diabetes Federation, ada 230 ribu kematian akibat diabetes di tahun 2021 (Usia 20-79) dan diperkirakan terus meningkat setiap tahunnya. Dalam rangka mendukung pencegahan Diabetes dan mendukung Program Universitas Pelita Harapan untuk membina Desa-desa binaannya, khususnya dalam mengatasi masalah Penyakit Diabetes, maka Program Studi Pendidikan Kimia, bekerja sama dengan pengurus RT 004/RW 003 Desa Ciakar melaksanakan kegiatan Penyuluhan Pencegahan Diabetes bagi masyarakat pada 5 Maret 2023 dan kegiatan Perbaikan Lapangan Olah Raga Warga pada 25 Maret 2023. Kedua kegiatan ini diharapkan memberikan penyadaran dan penguatan pemahaman masyarakat tentang pencegahan dan deteksi dini penyakit diabetes, dan mendorong masyarakat untuk tetap giat berolah raga.
Silver Nanoparticle Biosynthesis using Distimake vitifolius Extract for Enhancement of Antibacterial and Antioxidant Activity Tahya, Candra Yulius; Karnelasatri, Karnelasatri; Irawati, Wahyu; Munthe, Sri Wahyu Ningsih
Molekul Vol 19 No 2 (2024)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2024.19.2.10295

Abstract

ABSTRACT. The biological method for silver nanoparticle synthesis emphasizes green synthesis, which is faster, environmentally safer, facile, energy-efficient, and cost-effective. It provides good alternatives to physical and chemical methods. In this research, we have synthesized silver nanoparticles using D. vitifolius ethanolic extract. The 38 natural compounds of flavonoid, phenolic or polyphenol compositions have been determined by LC-MS/MS-QTOF which is carried out using UNIFI software equipped with a mass spectrum library of active substances from natural ingredients from the Waters database. Silver nanoparticle (Dv-AgNP) was characterized by using TEM and SEM where the average diameter of nanoparticle was seen <100 nm and confirmed by PSA analysis that the Z-average is 62.73 ± 0.71 nm. EDS spectrum confirmed the silver element as a major element of the particles. PI value of Dv-AgNP is 0.557, while the zeta potential is -17.37 ± 1.53 mV. Dv-AgNP can inhibit the growth of P. aeruginosa (amoxicillin resistant) with an inhibition zone of 15.83 ± 2.36 mm, and K. pneumoniae with an inhibition zone is 10.03 ± 0.55 mm. These are moderate inhibitory activities. The antioxidant result of the Dv-AgNP suspension solution shows that the IC50 is 0.58 mM. The IC50 of the crude extract is 752 ppm and is categorized as very weak antioxidant activity. Keywords: Antibacterial; D. vitifolius; silver nanoparticle.
Transesterifikasi Minyak Ikan Perak (Mene maculata) Dengan Katalis CaO Dari Cangkang Telur Ayam Tahya, Kartika; Tahya, Candra Yulius; Kainama, Healthy
Indonesian Journal of Chemical Research Vol 7 No 1 (2019): Edisi Bulan Juli (Edition For July)
Publisher : Jurusan Kimia, Fakultas Sains dan Teknologi, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/ijcr.2019.7-can

Abstract

Silver fish (Mene maculata) is a type of pelagic fish found in the Moluccas sea, this fish has a high oil content so that it is easy to extract the oil content for transesterification. The transesterification reaction of oil from silver fish oil needs a catalyst, and heterogenous catalyst is a better choice. This study was determined the fatty acid methyl ester composition of M. maculata by transesterification process using heterogeneous CaO catalyst from chicken egg shells through 3 steps i.e. oil isolation, CaO catalyst synthesis, and oil transesterification reactions. Oil isolation was carried out by soxhletation method using petroleum ether with the oil content was 13.51%. Synthesis of CaO catalyst was carried out by calcination at 1000 °C for 2 hours and then charactererized by XRD. Fish oil is transesterified using CaO catalyst in a ratio of 11% (w/v) of the mixture. Furthermore, fatty acid methyl esters obtained were analyzed using GC-MS. The results showed 6 methyl ester fatty acids as composition of transesterification products which were methyl myristic (11.85%), methyl palmitoleate (8.71%), methyl palmitic (25.13%), methyl oleic (9.49%), methyl stearic (10.04%), and methyl 5,8,11,14-eikosatetraenoate (1.96%).
Adsorption of Indigo Carmine Dye and Copper Ion by Kaolin from Bangka Island Tahya, Candra Yulius; Cornelia, Melanie; Siregar, Tagor M.; Karnelasatri, Karnelasatri
Indonesian Journal of Chemical Research Vol 11 No 1 (2023): Edition for May 2023
Publisher : Jurusan Kimia, Fakultas Sains dan Teknologi, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598//ijcr.2023.11-tah

Abstract

Indigo Carmine (IC) is a synthetic dye that might promote irritations, vomiting, and diarrhea when orally consumed in high concentrations. Copper is a dangerous heavy metal that tends to accumulate in organisms' cells as a pollutant. Hyperproduction of IC and accumulation of copper in water could cause an environmental problem that must be adequately addressed. Kaolin is found abundant on Bangka Island. Based on XRD analysis, Kaolin Island from Bangka Island consists of two important minerals, Kaolinite and Rectorite. Kaolin has chemical and physical properties, which make it useful in several applications, including as an adsorbent. This study aims to evaluate how Kaolin can adsorb copper ion from acid wastewater (pH < 0.5) and determine natural Kaolin's ability to adsorb IC dye from an aqueous solution. Many factors, including mixing time and number of doses of Kaolin, influence Kaolin's ability to absorb IC. The longer the stirring time, the more IC is absorbed. The optimal temperature for IC adsorption is 25˚C. The optimal kaolin dose for IC adsorption is 20% (m/v). Copper concentration after application of Kaolin tends to decrease, with optimal at 25.09% (m/v) dosage for 19.23% copper removal.
Analysis of Hydroquinone in Face Whitening Cream by UV-Vis Spectrophotometry and GC-MS Spectrometry Karnelasatri, Karnelasatri; Tahya, Candra Yulius; Adila, Mahda Uli; Hardy, Junius; Munthe, Sri Wahyu Ningsih
Indonesian Journal of Chemical Research Vol 11 No 3 (2024): Edition for January 2024
Publisher : Jurusan Kimia, Fakultas Sains dan Teknologi, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/ijcr.2024.11-kar

Abstract

The analytical method to determine the compound content in both food and cosmetic products must be carried out carefully to ensure the validity of the analysis results. Hydroquinone has been widely found to be used as an active whitening agent in whitening cream. Technological advances have led to illegal whitening creams becoming more accessible online. This study aims to examine the hydroquinone content in the whitening samples cream purchased from e-commerce by various analytical methods, such as FeCl3 reagent, cerimetric titration, UV-Vis spectrophotometry, and GC-MS spectrometer compared to the positive control hydroquinone. The results of the hydroquinone content by cerimetric titration and UV-Vis spectrophotometry methods were calculated quantitatively. Furthermore, the result compared through statistical tests showed a consistent hydroquinone content for both methods. Contrariwise, the GC-MS method showed negative results due to differences in the extraction process and solvent solubility. Based on the result obtained, can be concluded that all samples of whitening cream did not meet the requirements of BPOM No. 23 of 2019.
Biosynthesis of Silver Microparticles Using Spondias Dulcis Fruit Peel Extract and Its Antibacterial Activity Girsang, Thereshia Margaretta; Purba, Elisabeth; Simamora, Adela Rosalia; Sihombing, Chatrina Yohana; Inabuy, Marchella; Tahya, Candra Yulius
Walisongo Journal of Chemistry Vol. 7 No. 2 (2024): Walisongo Journal of Chemistry
Publisher : Department of Chemistry Faculty of Science and Technology Walisongo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/wjc.v7i2.22996

Abstract

In recent decades, the overuse and misuse of antibiotics, along with various social and economic factors, have accelerated the spread of antibiotic-resistant bacteria, including Klebsiella pneumoniae and Pseudomonas aeruginosa, both of which are Gram-negative pathogenic bacteria. Silver particles (AgPs) have garnered significant research interest over the years due to their diverse biological activities, particularly their antibacterial properties. The green synthesis method for silver particles involves synthesizing silver metal particles using natural materials derived from organisms such as plants, resulting in particles that are less harmful to human cells but highly toxic to pathogenic bacteria. Kedondong (Spondias dulcis) is a tropical fruit widely grown in South and Southeast Asia. The peels of this fruit often become organic waste with limited utility. To explore the potential of kedondong fruit peels, this study investigated the synthesis of silver particles using their extract. The ethanolic extract of kedondong fruit peels was analyzed using LC-MS/MS-QTOF, identifying 5 alkaloids, 21 flavonoids, and 17 terpenoid compounds. The total flavonoid and phenolic contents of the extract were determined to be 1.8918 and 12.8104 mg/g of extract, respectively. The silver particles synthesized in this study had an average size of 4641.97 micrometers and a zeta potential of 40.2 mV, as determined by PSA, and were confirmed as silver particles through P-XRD phase analysis. These silver particles exhibited strong antibacterial activity against P. aeruginosa, with an inhibition zone diameter of 19.43 mm, and moderate activity against K. pneumoniae, with an inhibition zone diameter of 11.50 mm, at a suspension concentration of 10 mg/mL. Notably, the P. aeruginosa strain used in this experiment was resistant to the antibiotic amoxicillin.
Co-Authors Adila, Mahda Uli Benedict Iglecias Sihombing Debora Sitinjak Elen Tiwery Elfani Bermuli, Jessica Elisabeth Wulan Kainde Friska J. Purba Friska Purba Gaspersz, Nelson Girsang, Thereshia Margaretta Greisnaningsi Greisnaningsi Hardy, Junius Iglecias Sihombing, Benedict Inabuy, Marchella Kainama, Healthy Karnelasatri Karnelasatri Karnelasatri, . Kelly Sinaga Kelly Sinaga Mega Gracelia Monaten Melanie Cornelia Melanie Cornelia, Melanie Muhammad Ikhsan Taipabu Munthe, Sri Wahyu Ningsih Purba, Elisabeth Purba, Friska Purba, Friska Juliana Sihombing, Chatrina Yohana Simamora, Adela Rosalia sinaga, kelly Sitinjak, Debora Suryani Tagor M Siregar Tagor M. Siregar Tahya, Kartika Tryani K. Junita Lumbantoruan Wahyu Irawati WAHYU IRAWATI