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Perbedaan Kadar Hemoglobin Ibu Hamil antara Wilayah Endemis dan Non-Endemis Cacing Buski di Kabupaten Hulu Sungai Utara Januarsih, Januarsih; Kirana, Rita; Rachmadi, Agus
Jurnal Skala Kesehatan Vol 17 No 1 (2026): Jurnal Skala Kesehatan Edisi Januari 2026
Publisher : Politeknik Kementerian Kesehatan Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/jsk.v17i1.518

Abstract

Anemia during pregnancy remains a major public health issue in Indonesia. One of the contributing factors is intestinal parasitic infection, such as (buski fluke), particularly in areas with poor sanitation and raw aquatic plant consumption. To compare hemoglobin levels among pregnant women in endemic and non-endemic areas of Fasciolopsis buski. This was a comparative cross-sectional study involving 124 pregnant women, consisting of 62 from endemic and 62 from non-endemic regions. Data were obtained through interviews, observations, and hemoglobin measurements using Hemocue®. Data were analyzed using an independent t-test at a 0.05 significance level. The mean hemoglobin level among pregnant women in endemic areas was 10.7 ± 1.1 g/dL, while in non-endemic areas it was 11.6 ± 1.0 g/dL. The t-test revealed a significant difference between the two groups (p = 0.001). The prevalence of anemia was 61.3% in endemic and 29.0% in non-endemic areas. There is a significant difference in hemoglobin levels between pregnant women living in endemic and non-endemic areas of Fasciolopsis buski. Endemicity of parasitic infection may contribute to higher anemia risk among pregnant women in endemic regions.
Phytochemical Screening and Toxicity Testing of Red Turmeric (Curcuma zedoaria) and White Turmeric (Curcuma mangga) Extracts in White Wistar Rats (Rattus norvegicus) Kirana, Rita; Rachmadi, Agus; Nurlailah
Jurnal Penelitian Pendidikan IPA Vol 12 No 2 (2026): In Progress
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v12i2.13497

Abstract

This study aimed to conduct phytochemical analysis and toxicity testing of Red Turmeric (Curcuma zedoaria) and White Turmeric (Curcuma mangga) extracts in male Wistar rats (Rattus norvegicus). This study employs an experimental design conducted at the Poltekkes Kemenkes Banjarmasin laboratory. Phytochemical screening was undertaken to detect bioactive compounds utilizing spectrophotometry for quantitative analysis, with each compound evaluated in triplicate. The experimental subjects were male Wistar rats, divided into two treatment groups (300 mg/kgBW and 2000 mg/kgBW), with observations recorded at multiple intervals (30 minutes to 14 days) post-administration. Toxicity indicators included physical symptoms such as skin conditions, lethargy, and survival status. Data were analyzed descriptively, calculating the mean and standard deviation for phytochemical content and employing frequency tables to highlight clinical symptom patterns. Results showed that both types of turmeric contain these compounds, with White Turmeric having higher phenolic (23.41 mg/g) and flavonoid (17.21 mg/g) contents than Red Turmeric (21.72 mg/g and 15.50 mg/g, respectively). These findings indicate a higher antioxidant potential in White Turmeric. In the toxicity test, two doses (300 mg/kgBW and 2000 mg/kgBW) were tested through observations of physical conditions, including skin and fur, as well as clinical symptoms such as lethargy, seizures, tremors, diarrhea, and survival status.