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All Journal Jurnal Anestesiologi Indonesia JIMKesmas (Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat) Syntax Literate: Jurnal Ilmiah Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Prima Medika Sains Infokes : Jurnal Ilmiah Rekam Medis dan Informasi Kesehatan JOURNAL LA MEDIHEALTICO Archives of The Medicine and Case Reports Bioscientia Medicina : Journal of Biomedicine and Translational Research Buletin Kedokteran dan Kesehatan Prima Jurnal Pendidikan Indonesia (Japendi) Eduvest - Journal of Universal Studies Ranah Research : Journal of Multidisciplinary Research and Development Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran JUKEJ: Jurnal Kesehatan Jompa
Simbolon, Boyke Marthin
Faculty Of Medicine, Universitas Prima Indonesia, Medan, Indonesia
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Hubungan Kepatuhan Minum Obat Antiretroviral dengan Kadar Viral Load pada Pasien HIV/AIDS dengan Koinfeksi Sifilis di RS H. Adam Malik Medan Sukma, Triza Via; Br Tarigan, Elviyanti; Simbolon, Boyke Marthin; Br Ginting, Masita Unjuk; Sitompul, Christian Michael Oloan
Ranah Research : Journal of Multidisciplinary Research and Development Vol. 8 No. 2 (2026): Ranah Research : Journal Of Multidisciplinary Research and Development
Publisher : Dinasti Research

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38035/rrj.v8i2.1999

Abstract

The Human Immunodeficiency Virus (HIV) is a virus that targets and attacks the human immune system. Acquired immunodeficiency syndrome (AIDS) is an immunosuppressive condition (syndrome) closely associated with various opportunistic infections, secondary neoplasms, and certain neurological manifestations resulting from HIV infection. Adherence to antiretroviral therapy is a key factor in achieving optimal viral load suppression. Viral load testing is one indicator of the success of ARV treatment. The higher the viral load in the blood, the faster HIV disease progresses. Objective: To determine the relationship between adherence to antiretroviral medication and viral load levels in HIV/AIDS patients with syphilis co-infection at H. Adam Malik General Hospital. Methods: This study used an analytical observational research design with purposive sampling techniques, namely measuring antiretroviral medication adherence and viral load levels in HIV/AIDS patients with syphilis co-infection. Results: Of the 100 study subjects, the majority were male (82%) with the largest age group being 25-35 years (48%). The results of the analysis showed a highly significant relationship between the MMAS-8 compliance level and viral load status (χ² = 31.248; df = 2; p = 0.001). There was a clear pattern showing that the higher the level of adherence, the greater the proportion of patients who achieved viral suppression. Only 39% of patients achieved high adherence (score of 8), and there was a dramatic difference in viral suppression between low adherence (14.8%), moderate adherence (55.9%), and high adherence (76.9%).
Co-Authors Akrom, Thoriq Bangun, Chrismas Gideon Br Ginting, Masita Unjuk Chairul, Muhammad Dewani, Yunita Dhillon, JagRoshen Singh Herisa Putri Anggraini Herisa Putri Anggraini Hutasoit, Maria Angelina Br Immanuella Pinem Larisma Simanullang Lina, Juliana Mei Riauly Wira Meldawati Meldawati Molek, Molek Mual Kristian Sinaga Muhammad Chairul Nasution, Muhammad Fauzi Novita Dwi Febrianty Novita Dwi Febrianty Petri Lumban Gaol Raynard A.K., Panta Leon Riris Grace Aprilia Riyani Susan Bt. Hasan Riyani Susan Bt. Hasan Riyani Susan Bt. Hasan Rosari, Anita Saragih, Ayu Theresia Siburian, Tissa Priscillya Deabitha Br Silaban, Wulantika Sinaga, Stevani Rose Br Sionia Delaroza Doloksaribu Sitompul, Christian Michael Oloan Sri Lestari Ramadhani Nasution Sukma, Triza Via Syahputra, Imam Tarigan, Elviyanti Tarigana, Elviyanti Br. Todung Donald Aposan Silalahi Wijaya, Wendi Yohania Premita