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Factors that influence refractive errors in premature infants Surasmiati, Ni Made Ayu; Handayani, Ariesanti Tri; Sutyawan, I Wayan Eka
Universa Medicina Vol. 43 No. 1 (2024)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2024.v43.44-50

Abstract

Background The prevalence of refractive errors is reported to be higher in children born preterm. Factors such as gestational age, birth weight, and retinopathy of prematurity status, have a significant impact on the refractive development in preterm infants. Prematurity and low birth weight affect the development of organ systems in infants, including the eyes. In addition to immature retinas, other eye conditions, such as refractive status, are also observed. This study aimed to determine the risk factors of refractive status, specifically refractive errors (spherical equivalent, astigmatism, and anisometropia) in premature infants at a tertiary hospital in Bali. MethodsA cross-sectional study was conducted involving 53 premature infants. This study collected samples from January to August 2023 at the Neonatal Intensive Care Unit of Prof. dr. IGNG Ngoerah General Hospital. Data regarding gender, gestational age, birth weight, retinal condition, spherical equivalent, and refractive disorders were collected. The relationship between risk factors and spherical equivalent, astigmatism, and anisometropia were analyzed using multiple regression analysis with statistical significance set at p<0.05. ResultsHypermetropia is the most common finding in premature infants, followed by myopia and astigmatism. The prevalence of myopia (9.4%) and astigmatism (5.7%) is also more common among newborns of gestational age ≤30 weeks (p=0.024). Chronological age was significantly associated with spherical equivalent (β=0.424; p=0.019). ConclusionIn premature infants, chronological age was the risk factor of spherical equivalent. Other risk factors were not associated with the prevalence of refractive errors among premature infants.
Strabismus Surgery for Traumatic Ocular Misalignment: Twelve Cases in Five Years: Poster Presentation - Case Series - Ophthalmologist SURASMIATI, NI MADE AYU; RATNASARI, NI LUH MADE NOVI; HENDRAWAN, KEVIN ANGGAKUSUMA; SUTYAWAN, I WAYAN EKA
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/pdg34475

Abstract

Introduction : Trauma can cause an ocular misalignment due to damage of extraocular muscles, nerves and orbital tissue around the eye. Direct trauma causing extraocular muscle rupture needs immediate surgery, meanwhile indirect trauma resulting in traumatic sixth nerve palsy or other reversible ocular misalignment without orbital floor fracture can be observed for six months. This study describe the characteristic of patients undergo single-step strabismus surgery for traumatic ocular misalignment, mechanism of injury, eye alignment, amount of ocular deviation before and after strabismus surgery. Case Illustration : This was a case series based on medical record of patients underwent strabismus surgery secondary to head or eye injury from 2017 until 2022. Discussion : Twelve individuals with post-traumatic strabismus correction participated in this study. All subjects were male age ranging from 18-51 years. Direct trauma was observed in 6 (50%) patients causing medial rectus muscle rupture in 4 patients and inferior rectus muscle rupture in 2 patients. Indirect trauma was observed in 6 (50%) patients caused by sixth nerve palsy on 4 patients The misalignment was exotropia, esotropia, and hypertropia with amount of 5, 4, and 3 respectively. The deviation was between 30-90 prism dioptre (PD) and 7 (58%) patients had deviation less than 65 PD. Strabismus surgery performed was muscle transposition with or without recession of the antagonist muscle. Conclusion : Single step surgery for traumatic ocular misalignment can provide good result in cases of deviation less than 65 PD
Congenital Orbital Teratoma of the Newborn: A Rare Case Report Yuliawati, Putu; Wetarini, Krisnhaliani; Sutyawan, I Wayan Eka; Surasmiati, Ni Made Ayu; Utari, Ni Made Laksmi; Sunariasih, Ni Nyoman
Jurnal Kedokteran Brawijaya Vol. 33 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.02.19

Abstract

Congenital orbital teratoma is a rare and complex congenital anomaly due to abnormal tissue growth within the orbit. This case report aims to highlight the significance of early prenatal screening in identifying congenital orbital teratoma and its potential complications. A 6-day-old male newborn presented with macrocephaly and a unilateral massive protrusion of the left eye. Prenatal ultrasonography performed at 36 weeks gestation showed a suspicion of fetal craniofacial mass. Further brain CT scan revealed an orbital heterogeneous mass, with calcified components dominantly in the anterior and middle cranial fossa into the left orbit, which was subsequently diagnosed as congenital orbital teratoma associated with non-communicating hydrocephalus. This finding prompted an urgent ventriculoperitoneal (VP) shunt. Unfortunately, despite prompt intervention, the patient passed away after the procedure. Pathological examination was compatible with an immature teratoma. Multidisciplinary management is warranted to improve diagnostic screening and refine management strategies for better outcomes in such cases.
Thrombocytopenia as a Clinical Biomarker of Retinopathy of Prematurity Sutyawan, I Wayan Eka; Surasmiati, Ni Made Ayu; Agrasidi, Putu Anindya; Dwianggita, Priscilla; Anggara, Stephanus Anggara
Folia Medica Indonesiana Vol. 59, No. 4
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Highlights: • This is the first systematic review investigating thrombocytopenia and its association with retinopathy of prematurity. • Thrombocytopenia can be a useful clinical biomarker in retinopathy of prematurity screening, considering the quick, affordable, and widespread availability of the examination. Abstract Retinopathy of prematurity (ROP) is the primary cause of childhood blindness. It arises from the underdevelopment of retinal blood vessels in premature infants. Platelets have a vital function in the regulation of angiogenesis. Thus, thrombocytopenia may contribute to the progression of ROP. The objective of this systematic study was to examine the relationship between thrombocytopenia and ROP. The PubMed and Cochrane Library databases were accessed to search for retrospective, case-control, and cross-sectional studies. This study adhered to the guidelines outlined by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The literature search resulted in nine records to be analyzed in our review. All the selected studies were conducted between 2017 and 2022. Seven studies reported that the prevalence of thrombocytopenia in infants with ROP ranged from 18.37% to 71%. The frequency of thrombocytopenia in preterm children without ROP was between 5.71% and 21%. Thrombocytopenia was identified as a risk factor for ROP in seven studies, with the odds ratio (OR) for thrombocytopenia ranging from 2.8 to 6.69. Thrombocytopenia in premature infants can potentially serve as a clinical biomarker in the screening of type 1 ROP. This finding suggests that thrombocytopenia may contribute to the pathophysiology of ROP. Further research is necessary to determine the critical threshold platelet count for thrombocytopenia in infants with ROP.