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All Journal Indonesian Journal of Business and Entrepreneurship (IJBE) Jurnal Aplikasi Bisnis dan Manajemen (JABM) E-Journal Journal Of Nursing Practice Medica Hospitalia Magna Neurologica Neurona Business, Entrepreneurship, and Management Journal
Retnaningsih
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Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Prediksi Hiperlaktatemia Terhadap Sepsis Dan Luaran Buruk Pada Pasien Intracerebral Hemorrhage Retnaningsih; Tugasworo, Dodik; Priatmaja, Ageng; Supardi
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 42 No 2 (2026): Volume 42, No 2 - Maret 2026
Publisher : PERDOSNI

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Abstract

Introduction: Sepsis is a serious complication and major cause of mortality among intracerebral hemorrhage (ICH) patients in the intensive care unit (ICU). Serum lactate is commonly used as a prognostic biochemical marker for sepsis in critically ill patients. Aims: This study aimed to evaluate the relationship between serum lactate levels, sepsis incidence, and clinical outcomes in ICH patients in ICU of Dr. Kariadi Hospital. Methods: A retrospective observational cohort study was performed on 30 ICH patients hospitalized in the ICU during 2024. Data normality tested using Shapiro-Wilk; non-normal data were analysed by Mann-Whitney U, categorical data by Chi-square test. Results: Among 30 patients (12 males, 18 females), 20 had hyperlactatemia (>2 mmol/L). The hyperlactatemia group had higher sepsis incidence (90% vs. 50%, p=0.014), MODS (70% vs. 30%, p=0.037), high NLR (>8; 80% vs. 40%, p=0.028), longer ventilator (>8 days; 75% vs. 40%, p=0.007), and LOS (>8 days; 75% vs. 40%, p=0.007). Discussion: Routine serum lactate monitoring in ICH ICU patients is recommended for early detection and prognosis of sepsis. Larger prospective studies are needed to validate these findings. Keywords: ICU, intracerebral haemorrhage, lactate, prognosis, sepsis
Co-Authors Andhitara, Yovita Ardhini, Rahmi Arlia Ayu Damayanti Ayu Imamatun Nisa Azzara, Rana Chyntia Baarid Luqman Hamidi David Noor Umam Daynuri Dodik Tugasworo Dwi Febryanto Dyah Pranani DYAN ARINTOWATI Erliza Noor Fitria Handayani Gautama Sastra Waskita Harianto, Erlangga Pradipta Hexanto Muhartomo, Hexanto Injesus, Elioting Bich Jeffri Nagasastra Kurnianto, Aditya Machin, Abdulloh Mahendra, Muhammad Chosasih Megawati Simanjuntak Mohammad Fathul Qorib Mustofa, Aila Pasmanasari, Elta Diah Priatmaja, Ageng Rahmana, Adhitya Sawal Sartono, Sawal Shabrina Nur Zidny Simamora, Rosinondang Deolita Suhendi Supardi Umam, Hamid Faqih Yandri Zatalini, Halimah