Bintoro, Siprianus Ugroseno Yudho
Department Of Internal Medicine, Faculty Of Medicine, Universitas Airlangga, Jl. Mayjen Prof. Dr. Moestopo No.47, Surabaya 60132

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Journal : Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya

Management and quality of life extranodal non hodgkin lymphoma of testis Bagus Aulia Mahdi; Pradana Zaky Romadhon; Ugroseno Yudho Bintoro; Merlyna Savitri; Putu Niken Ayu Amrita; Muhammad Noor Diansyah; Ami Ashriati Prayoga; Kartika Prahasanti
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 6, No 1 (2022): Journal Qanun Medika Vol 6 No 01
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v6i1.7610

Abstract

Extranodal non-Hodgkin lymphoma still seems to be a rare case and an issue to discuss a lot. Clinical evidence and guidelines on treatment have not yet been widely published and accessible. We present a case of a forty-five-year-old male with the chief complaint of a bulky and huge right mass in the testis with an ulcer on it. The patient underwent an orchiectomy, and the biopsy showed a malignant round cell tumor, suspected as non-Hodgkin lymphoma. The patient then received the following treatment: chemotherapy with R-CHOP regiment every three weeks, consisting of 6 cycles showing shrinkage size of the testis by day 7 and final complete response after 4th cycle with ADE grade 0 no sexual activity disorder after chemotherapy. This raises hope in developing treatment modalities that the right choice on chemotherapy regimen with complete control on the drug effects may improve clinical outcome and patient’s quality of life.
Correlation between Neutrophil-to-Lymphocyte Ratio and Severity of Community-Acquired Pneumonia in Patients Almira, Naufalia Ghina; Hasan, Helmia; Wardhani, Puspa; Hernaningsih, Yetti; Bintoro, Siprianus Ugroseno Yudho; Romadhon, Pradana Zaky
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 02 (2025): Qanun Medika Vol 09 No 02 July 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i02.25024

Abstract

The high morbidity and mortality rates due to pneumonia in developing countries indicate that a more affordable marker is needed to determine the degree of inflammation in cases of pneumonia infection. The neutrophil-to-lymphocyte ratio (NLR) is a simple indicator used extensively in evaluating the systemic inflammatory response. An observational cross-sectional study of 297 pneumonia patients was conducted using medical records as the source document. The patients’ blood was taken during the hospital admission to obtain neutrophil and lymphocyte values. Meanwhile, the PSI score was used during the hospital admission to assess the severity of the pneumonia. Bivariate analysis using Spearman correlation was used to determine the correlation between NLR and pneumonia severity. The ROC curve was used to determine the cut-off value of NLR to distinguish mild from severe patients. The results of the Spearman correlation test analysis showed that the correlation between the NLR and the pneumonia severity was significantly positive (r = 0.130; p = 0.025). Furthermore, the median NLR value was higher in patients with severe pneumonia than in those with milder pneumonia severity (13.01 vs. 11.79 vs. 6.75). The NLR cut-off value of 9.07 was obtained to differentiate patients with mild severity and those with more severe disease. In conclusion, there is a correlation between the neutrophil-to-lymphocyte ratio and the severity of patients’ pneumonia.