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CATHETER DURATION AND THE RISK OF SEPSIS IN PREMATURE BABIES WITH UMBILICAL VEIN CATHETERS Hartojo, Hartojo; Utomo, Martono Tri
Indonesian Journal of Tropical and Infectious Disease Vol 3, No 1 (2012)
Publisher : Institute of Topical Disease

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (97.254 KB)

Abstract

Umbilical catheters are frequently required in the management of severely ill premature babies. The risk of complications may increase with duration of UVC use. Objective: To determine whether the risk of central line-associated bloodstream infections (CLA-BSIs) and sepsis remained constant over the duration of umbilical vein catheters (UVCs) in high-risk premature neonates.Methods:retrospective analysis. The data were collected from the medical record of high risk premature neonates who had a UVC placed in neonatal care unit of Husada Utama Hospital between April 1st 2008 to April 30th 2011 with purposive sampling. Catheter duration was observed before and after 14 days on placement. Blood and UVC culture was performed to establish the risk of CLA-BSIs and sepsis. Chi-square and logistic regression analysis were performed in the laboratorium data. Result: A total 44 high risk premature babies with UVCs were enrolled (sepsis group: n = 23 and non sepsis group: n = 21). Baseline demographics were similar between the groups. 15 babies in sepsis group have UVCs duration > 14 days, and 8 babies have UVCs < 14 days (p = 0.533). Days of UVC < 14 days show UVCs culture performance in 11 babies with positive evidence, blood culture performance shows negative in 21 babies (p = 0.516). Days of UVC >14 days show blood culture performance in 11 babies with positive evidence, UVCs culture performance is negative in 18 babies (p = 0.456). Burkholderia cepacia and Klebsiella pneumonia mostly appeared in blood culture performance. 25% of UVC culture performance shows Pseudomonas aeroginosa. Conclusions: The catheter duration have no significant differencein risk of sepsis in premature babies with Umbilical Vein Catheters.
DETERMINAN “PICKY EATER” (PILIH-PILIH MAKANAN) PADA ANAK USIA 1- 3 TAHUN (Studi di Wilayah Kerja Puskesmas Jabon Sidoarjo) Kusumawardhani, Niken; Rachmat Hargono, Windhu Purnomo; Martono Tri Utomo Sri Andari, Siti Nurul Hidayat
HOSPITAL MAJAPAHIT (JURNAL ILMIAH KESEHATAN POLITEKNIK KESEHATAN MAJAPAHIT) Vol 5, No 2 (2013): HOSPITAL MAJAPAHIT VOL 5 NO 2
Publisher : HOSPITAL MAJAPAHIT (JURNAL ILMIAH KESEHATAN POLITEKNIK KESEHATAN MAJAPAHIT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.10475/hm.v5i2.459

Abstract

Picky eater is one of the important issues in child growth that have to be concerned by parents and health practitioners, due to the negative effect of imbalance increasing of weight, important nutrition defeciency, also lack of variation of food consumptions. If this issue does not immediately treated it can cause a long term effect of an unhealthy or slow development and growth in children. Sample of population used in this research are all children aged 1-3 years old in Posyandu of Puskesmas Jabon in March until May 2013. The type of this study was an analytic with case control design study. The total of sample was 106 children devided in case (n=53) and control groups (n=53) and using Multiple Logistic Regression Test. The outcome of this research are showing all illness that have been suffered by all children in last 3 months, lack of interaction between mother and children, parents selective food behavior, not given enough exclusive breastfed for 6 months, given weaning food less than or more than 6 months, children is raised by people other than parents, socio-cultural dietetic view, unmatching frequencies between consumption and age, improper mealtimes, and improper feeding techniques are all crucial in affeting selective eating disorder in children aged 1-3 years in area of work of Puskesmas Jabon Sidoarjo in 2013.Key words: Picky eater disorder
ANALISIS FAKTOR RISIKO DAN LUARAN DARI PENGGUNAAN TERAPI ANTIBIOTIK EMPIRIK JANGKA PANJANG PADA BAYI DENGAN BERAT LAHIR SANGAT RENDAH DALAM KONDISI SEPSIS Reza, Muhammad; Sampurna, Mahendra Tri Arif; Handayani, Kartika Darma; Angelika, Dina; Utomo, Martono Tri; Etika, Risa; Harianto, Agus
Majalah Kesehatan FKUB Vol 6, No 4 (2019): Majalah Kesehatan
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (682.154 KB) | DOI: 10.21776/ub.majalahkesehatan.2019.006.04.4

Abstract

Terapi antibiotik berkepanjangan pada neonatus menyebabkan beberapa konsekuensi negatif meliputi resistensi antibiotik, sepsis awitan lambat, enterocolitis nekrotikan (EKN), lama rawat lebih panjang, dan peningkatan mortalitas. Semua faktor tersebut mempengaruhi efisiensi biaya pelayanan rumah sakit di era Jaminan Kesehatan Nasional. Penelitian ini bertujuan untuk menganalisis faktor risiko dan luaran dari terapi antibiotik berkepanjangan pada bayi berat lahir sangat rendah (BBLSR) dengan sepsis. Desain penelitian adalah studi retrospektif pada BBLSR dengan sepsis di Neonatal Intensive Care Unit (NICU), RSUD Dr. Soetomo, Surabaya sejak Januari-Desember 2017 dilakukan dengan membandingkan luaran antara kelompok I yang mendapat terapi antibiotik empirik kurang dari sama dengan 2 minggu dengan kelompok II yang mendapat terapi antibiotik empirik lebih dari 2 minggu empirik. Dari 87 bayi yang termasuk ke dalam studi, 37 bayi termasuk dalam kelompok I dan 50 bayi dalam kelompok II. Rerata durasi terapi antibiotik pada kelompok I dan kelompok II adalah 9,2±2,5 dan 17,9±3,2 hari, dengan lama rawat inap 19,7±8,5 dan 27,2±13,1 hari. Analisis faktor risiko menunjukkan bahwa BBLSR terutama 1000 gram (p < 0,001), ventilasi mekanik invasif (p < 0,001), ventilasi mekanik non-invasif (p < 0,001), korioamnionitis (p = 0,003), penyakit maternal (p = 0,004), kehamilan multipel (p = 0,03) merupakan faktor risiko mendapatkan terapi antibiotik empirik berkepanjangan. Luaran dari terapi antibiotik empirik berkepanjangan adalah 41 (47%) bayi mengalami sepsis awitan lambat,  15 (17%) bayi dengan EKN, dan 11 (12%) bayi meninggal. Mortalitas bayi dengan sepsis awitan lambat (p < 0,001) dan EKN (p = 0,02) lebih tinggi pada kelompok II dibandingkan kelompok I. Kesimpulannya, terapi antibiotik empirik berkepanjangan meningkatkan angka kejadian sepsis awitan lambat, enterocolitis nekrotikan, lama rawat, dan mortalitas BBLSR di NICU yang berdampak meningkatkan biaya pelayanan rumah sakit.  
Risk Factors of Rebound Hyperbilirubinemia in Post Phototherapy Hyperbilirubinemia Infants Alexander Leonard Caesar Josediputra; Martono Tri Utomo; Risa Etika
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16774

Abstract

Background: Post phototherapy rebound hyperbilirubinemia is a cause for readmission in some infants.However, this phenomenon data of rebound hyperbilirubinemia is lacking from Indonesia. Our study aimsto describe the risk factor of post phototherapy rebound hyperbilirubinemia in the infant.Method: Cross-sectional study of all infants with indirect hyperbilirubinemia who were treated phototherapyaccording to standard guidelines in neonate intermediate unit Dr. Soetomo hospital for 6 months from June2017 until December 2017. Bilirubin was measured 24 hours after phototherapy. Bilirubin rebound isconsidered as increasing total serum bilirubin that needs reinstitution of phototherapy.Result: A total of 53 (44.9%) infants developed rebound hyperbilirubinemia. We revealed the following riskfactor for rebound hyperbilirubinemia was the onset of jaundice on < 3 days, (10 babies, p <0.05). Otherresults are 30 (56.6%) female infants, 39 (73%) birth weight < 2500 g, 36 (67%) infants with a history ofcesarean section, and 38 (71%) preterm infants but there are not statistically significant.Conclusion: Post phototherapy rebound hyperbilirubinemia should be considered in the onset of jaundice< 3 days.
Galactooligosaccharide (GOS) Fortified Formula Feeding in Premature Infants Martono Tri Utomo; Muhammad Reza; Risa Etika; Talitha Y. Aden; Iwan S. Handoko; Ruth A. Alexander
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17587

Abstract

Background: Nutritional problems are one of the serious problems in low birth weight or preterm infants. This causes medical and nutrition management of premature infants to be more individual. Objective: To evaluate the outcome of the premature infants with Galactooligosaccharides (GOS) fortified formula feedingMethods: This was prospective, open label cohort study that conducted during March- December 2019 in Neonatology Unit at the one of the main referral hospitals in East Java, Indonesia. The population of the study was very low birth weight infants (1,000 g - ≤1,500g) who needed formula feeding. Weight, body length, head circumference, fecal models and the incidence of diarrhea, colic, regurgitation, and vomiting was observed. Patients were observed for 28 days or adjusted according to length of stay.Results: Totally, 20 infants were included. Mean birth weight was 1236.2±148.5 grams. Mean total volume Galactooligosaccharides fortified formula at the start of recruitment was 209.4±46.1 ml and at the end of observation was 267.9±41.2 ml. There were change in amount and consistency of feces before and after intervention. No patient experienced adverse events (diarrhea, colic, regurgitation or vomiting) while consuming Galactooligosaccharides fortified formula. Conclusion: Galactooligosaccharides fortified formula in premature infant formula did not have a detrimental effect on premature infants and did not cause intolerance
Echocardiographic Study in Preterm Infant with Hemodynamic Significant Patent Ductus Arteriosus Sunny Mariana Samosir; Martono Tri Utomo; Mahrus A. Rahman; Risa Etika; Dina Angelika; Kartika Darma Handayani; Agus Harianto
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17650

Abstract

Background: Potential complications of hemodynamic significant patent ductus arteriosus (hsPDA) after birth include heart failure, need for respiratory support, renal disfunction, intraventricular hemorrhage, as well as long term altered growth and development. Nevertheless, clinical signs of patent ductus arteriosus (PDA) are not sensitive and specific enough. Therefore, echocardiography still remains the preferred method to evaluate the ductal patency in preterm infant. The present study aimed to evaluate the echocardiography characteristic in preterm infant with hsPDA.Methods: A cross-sectional study was conducted on preterm infants aged 3-7 days with 24-336/7 weeks of gestation. Data taken were demographic, clinical and echocardiography. Diagnosis of hsPDA was carried out by echocardiography; defined as >1.5mm diameter of ductus and >1.4 left pulmonal artery and aorta (La/Ao) ratio. The statistical analysis was undertaken using SPSS 21.0.Results: There were 11 out of 52 preterm infants diagnosed hsPDA. Mean birth weight was 1213±293 gram; Mean gestational age was 30.72±2.01 weeks. In hsPDA group, mean ductus diameter was 2.84±0.93 mm, mean La/Ao ratio was 1.56±0.26, and mean ejection fraction (EF) was 71.55±5.72%.Conclusion: Echocardiographic evaluation is important for addressing hsPDA in preterm infants.
Low-Hemoglobin Levels During Pregnancy with Low-Birth Weight: A Systematic Review and Meta-Analysis Lucyana Septia Pramita; Widati Fatmaningrum; Martono Tri Utomo; Muhammad Ilham Aldika Akbar
Pediomaternal Nursing Journal Vol. 7 No. 1 (2021): VOLUME 7 NO 1 MARCH 2021
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/pmnj.v7i1.24184

Abstract

Introduction: Low birth weight (LBW)  is one of the main risk factors for neonatal morbidity and mortality. Anemia in developing countries is still quite high compared to developed countries. Low hemoglobin levels in pregnancy can affect the birth of low birth weight babies.Methods: This study used a systematic review method. Studies published between 2015 and 2019. Search for articles was reviewed systematically through Scopus, ScienceDirect, Cochrane, and PubMed databases. The final results obtained 10 articles following the inclusion and exclusion criteria. Calculation result using Meta-Analysis with help of Comprehensive Meta-Analysis (CMA) software.Results: Compare the odds ratio and confidence interval of hemoglobin levels compared to low birth weight events. The results obtained OR 1.449 (95% CI 0.964 – 2.177) and p-Value 0.074 so that there is no relationship of hemoglobin levels in pregnant women ≤ 11gr / dL with the incidence of low birth weight babies. In the heterogeneity test results, I-Squared results obtained by 79.191%, which indicates the value of I-squared heterogeneity> 50% so that the sample used is heterogeneous. Maternal age less than 20 years or more than 35 years, number of parity, pregnancy spacing, and number of problems in the assessment of pregnancy and previous labor.Conclusion: There is no correlation between low maternal hemoglobin levels with the incidence of low birth weight because there are other factors that can affect outcomes such as different respondent characteristics, number of samples, different research countries, different trimester of pregnancy and other factors that can cause research bias.
The Effect of Antenatal Corticosteroid Therapy to Respiratory Distress Syndrome Event on Preterm Infants in Surabaya Devy Putri Zenita; Martono Tri Utomo; Ernawati Darmawan
Biomolecular and Health Science Journal Vol. 1 No. 1 (2018): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (911.807 KB) | DOI: 10.20473/bhsj.v1i1.8217

Abstract

ABSTARCTIntroductions: One of the most common cause of morbidity and mortality in premature infants is respiratory distress syndrome (RDS). Several studies have shown that a single dose administration of antenatal corticosteroid therapy in women who are at high risk for premature delivery was associated with decreased incidence of RDS. The study aims to determine the effect of antenatal corticosteroid therapy on the incidence of RDS in prematurity in the Department of Child Health Hospital Dr. Soetomo.Methods: Analytic observational case-control design study was used for this research. Samples were taken from the medical records of RDS patients in premature baby and non-RDS with 36 samples in each group.Results: Antenatal corticosteroid therapy has effect in RDS incidence (p = 0.016). While the results of the odds ratio was 0.298 (with 95% CI 0.110 to 0.810), it means that premature infants with antenatal corticosteroid therapy has 0.298 times lower risk than those who were not given antenatal corticosteroid therapy.Conclusion: Antenatal corticosteroid therapy did not provide a direct relathionship to the incidence of respiratory distress syndrome in premature infants, but it a protective factor that can reduce the incidence of RDS in prematurity.
The Effect of Cigarette Smoke Exposure in the Fetal Growth and Fetal Development of Mice (Mus musculus) Endy Novryan Ridwan; Martono Tri Utomo; Harianto Notopuro
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 11 No. 1 (2020): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V11I12020.13-17

Abstract

Introduction: This research aims to investigate and observe the effect of cigarette smoke exposure in the fetal growth and fetal development of mice (Mus musculus).  Methods: This was an experiment with post-test only control group design. The sample of the research was 36 pregnant mice which were randomly divided into 2 groups: control group (K) pregnant mice which inhaled ambient air without cigarette smoke exposure, and treatment group (P) pregnant mice which were given cigarette smoke exposure for 14 days with 2 bars of cigarette each day.  Results: The results showed a significant difference in the fetal birth weight between the group exposed to cigarette smoke (p < 0.05) compared with the control group. Fetal defect and stillbirth were not found in this research. Conclusion: The exposure of cigarette smoke gave negative effects of fetal growth and development because of the free radicals generated.
Analysis of Factors Affecting the Development Status of Toddlers in Simomulyo Health Center Surabaya Dyah Aisyah Rachmawatie; Farida Fitriana; Martono Tri Utomo; Pudji Lestari
Jurnal KESANS : Kesehatan dan Sains Vol 1 No 6 (2022): KESANS : International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v1i6.72

Abstract

Background: Development is one of the important things for the future of a child. The most crucial development occurs during the first five years of a child's life, this time is often called the golden period. At this time all the development of children must be by their age so that in the future there are no developmental delays. A child's development can be influenced by several factors, both internal and external factors. Based on previous research as many as 5-10% of Indonesian children experience general developmental delays, so the development of Indonesian children still requires serious attention. Therefore, this study aims to analyze factors that affect the development status of toddlers. Method: This study is an observational analytical study using a cross-sectional approach. With a sample number of 100 toddlers in the working area of Simomulyo Health Center that meets the criteria of inclusion and uses consecutive sampling techniques. Independent variables in the study were birth weight, nutritional status of toddlers, parents' last education, economic status, history of disease in toddlers, and history of exclusive breast milk. While the dependent variable in this study is the status of development. The chi-square statistical test is used to determine the significant level of data obtained at the meaningful level of ? =0.05. Results: The results of the study found 90% experienced appropriate developmental status, 86% had normal nutritional status based on BB / U, 45% had normal nutritional status based on TB / U, 64% had normal nutritional status based on BB / TB, 82% of toddler parents had the last high education, 67% of toddlers have economic status ?UMR, 50% of toddlers have a history of pain ?2 times sick and 56% of toddlers get exclusive breast milk ?6 months. From the results of statistical tests chi-square obtained birth weight ? = 0.444 (??0.05), nutritional status based on BB / U ? = 0.578 (??0.05), nutritional status based on TB / U ? = 0.375 (??0.05), nutritional status based on BB / TB ? = 0,706 (??0.05), parental education ?=0.488 (??0.05), economic status ?=0.103 (??0.05), history of childhood disease ?=0.046 (?<0.05), exclusive breast milk history ?=0.002 (?<0.05). It means that there is no relationship between developmental status with birth weight, nutritional status, parents' last education, economic status. However, there is a relationship between developmental status and a history of toddler disease, and a history of exclusive breast milk. Conclusion: A toddler's history of disease and a history of exclusive breast milk have relationships that can affect a toddler's development.
Co-Authors Abdurachman Abdurachman Adinda Juwita Syakila Elizafanti Aditiawarman Aditiawarman, Aditiawarman AGUS HARIANTO Agus Sulistyono Akbas, Ahmad Maulana Ifan Aldika Akbar, Muhammad Ilham Alexander Leonard Caesar Josediputra Anindya Kusuma Winahyu Arinda Putri Auna Vanadia Aurelia Margaretha Manurung Azra Fauziyah Azyanti Bagus Setyoboedi Bintoro, Siprianus Ugroseno Yudho Devy Putri Zenita Dina Angelika Dyah Aisyah Rachmawatie Endy Novryan Ridwan Ernawati Ernawati Esti Isyroofanaa Esti Yunitasari Faizah, Zakiyatul Farahdina Farahdina Fasha Rudilla Putri Firyal Nadiah Rahmah Fitriana, Farida Gatut Hardianto, Gatut Hanik Badriyah Hidayati,* Mohammad Hasan Machfoed,* Kuntoro,** Soetojo,*** Budi Santoso,**** Suroto,***** Budi Utomo****** Harianto Notopuro Hartojo Hartojo, Hartojo Hasanah Nurbawena Hermanto Tri Joewono INDRA YULIATI, INDRA Irda Triyas Shanty Iswara, Salma 'Afindi Iwan S. Handoko Kartika Darma Handayani Lucyana Septia Pramita Luwes Sekar Ayu Wardhani Mahrus A Rahman, Mahrus A ManikRetno Wahyunitisari Melinda Masturina Mia Ratwita Andarsini Muhammad Miftahussurur Muhammad Reza Muhammad Reza Nabila Annisa Harum Ni Nyoman Metriani Nesa Nicholas Fernando Purnomo Niken Kusumawardhani, Niken Octariyandra, Syania Mega Panada Sedianing Drastita Prastiya Indra Gunawan Prihaningtyas, Rendi Aji Primadita Syahbani Pudji Lestari Rachmat Hargono Rendi Aji Prihaningtyas Rendi Aji Prihaningtyas Risa Etika, Risa Rize Budi Amalia Rohma, Annisa Nur Ruth A. Alexander Salsabila Hansa Kamal Sampurna, Mahendra Tri Arif Sjamsul Arief Sjamsul Arief Sjamsul Arief, Sjamsul Sulistiawati Sulistiawati Sunny Mariana Samosir Talitha Y. Aden Ucik Nurul Hidayati Widati Fatmaningrum Woro Setia Ningtyas Yeni Riskawati Yustika Ayustira Karim