Article Per Year (5 Year)
p-Index From 2021 - 2026
2.386
P-Index
This Author published in this journals
All Journal Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Indonesian Journal of Pharmaceutical Science and Technology Pharmacon Acta Pharmaciae Indonesia : Acta Pharm Indo SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) JCPS (Journal of Current Pharmaceutical Sciences) Jurnal Pengabdian Kepada Masyarakat MEMBANGUN NEGERI Prosiding Seminar Nasional Program Pengabdian Masyarakat Borneo Journal of Pharmacy
Vella Lailli Damarwati
Universitas Muhammadiyah Yogyakarta
Agriculture, Biological Sciences & Forestry Humanities Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

Published : 16 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 16 Documents
Search

 1   2 
PENINGKATAN KEMAMPUAN ANTIOKSIDAN PADA KRIM KULIT JERUK NIPIS (Citrus aurantifolia S) MENGGUNAKAN VCO DENGAN METODE DPPH Dyani Primasari Sukamdi; Sabtanti Harimurti; Kunniya Amany; Vella Lailli Damarwati
JCPS (Journal of Current Pharmaceutical Sciences) Vol 7 No 2 (2024): March 2024
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Lime peel (Citrus aurantifolia S.) is rich in flavonoids, tannins, and coumarins so that it can act as an antioxidant. It can be formulated with Virgin Coconut Oil (VCO) into a cream to protect the skin and prevent aging. This study aims to determine the antioxidant activity of cream preparations containing lime peel extract with DPPH method and to determine whether the concentration of VCO can affect the physical evaluation and antioxidant activity of cream preparations. Lime peel was extracted by maceration method using 96% ethanol and cream were made using various VCO concentrations (30%, 35% and 40%). The three formulas were physically tested to determine the effect of adding VCO concentration to the physical quality of the cream. Data analysis was carried out using the One-Way Anova method and the results of the adhesive power test, dispersion and pH concluded that the significance was, therefore the addition of VCO concentration does not affect the value on adhesion, spread ability and pH. The IC50 results obtained for formulas I, II and III are 31.78 ppm, respectively; 29.64 ppm ; 26.95 ppm. Data was statistically tested using One-Way Anova, the results showed that lime peel extract cream with the addition of VCO affected antioxidant activity in cream preparations. Where the greater the concentration of VCO used in lime peel cream, the greater the antioxidant activity. Keywords : Lime peel, cream, extract, VCO, antioxidants
Evaluation of physical and chemical stability of semi-solid preparations towards beyond-use date Sukamdi, Dyani Primasari; Dewinda, Zulfa Sekar; Damarwati, Vella Lailli; Maziyyah, Nurul; Ningrum, Dhecella Winy Cintya
Acta Pharmaciae Indonesia Vol 11 No 2 (2023): Acta Pharmaciae Indonesia: Acta Pharm Indo
Publisher : Pharmacy Department, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.api.2023.11.2.9260

Abstract

Background: Semi-solid formulations require careful consideration due to potential drug interactions and incompatibilities. The stability of these compounds is crucial for determining the quality of a preparation, often assessed by its designated shelf life. Objective: This research synthesizes previous studies to provide a comprehensive assessment of the quality and stability of semi-solid drugs, focusing on evaluating their physical and chemical stability in relation to the Beyond Use Date (BUD). Methods: A literature review was conducted using the Google Scholar database, yielding eight articles that met the established inclusion and exclusion criteria and were pertinent to the research topic. Results: The evaluations of physical stability indicated that preparations are stable when stored under standard conditions, away from light, and when formulated with suitable bases. The chemical stability assessments revealed a decline in potency or concentration at elevated temperatures. Conclusion: The study concludes that, within the parameters of stability evaluated, semi-solid drug preparations remain viable for use.
Formulation Sunscreen Spray Gel of Vetiveria zizanioides (L.) Nash Root Infusion Damarwati, Vella Lailli; Fajarani, Rizky Anita; Sabeta, Meilidya Vani; Kurniawan, Muhammad Fariez; Winanta, Aji
Indonesian Journal of Pharmaceutical Science and Technology 2025: Vol. 12 Suppl. 1 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12s1.59024

Abstract

Vetiveria zizanioides (L.) Nash is one of the plants with high flavonoid compound content with antioxidant activity. This study aims to formulate a spray gel of the root of Vetiveria zizanioides (L.) Nash infusion determines UV protection and observes the level of irritation caused by the application.  This study used formulas at variations concentrations FI 1%, FII 5%, and FIII 10%. The formulas observed flavonoid content, sun protection factor (SPF) value, and irritation index. Flavonoid content was tested using the Willstatter method. The SPF value was determined in vitro using UV-spectrophotometer, while the irritation test was conducted using the Draize test method. The SPF value test results showed that Formula 0 (F0), FI, FII, FIII, and the commercial preparation had SPF values of 0.355, 2.856, 5.324, 6.634, and 13.438, respectively. Meanwhile, the irritation test obtained an irritation infection of 0.3 in the commercial preparation and 0.6 in F3. Therefore, FII has the potential to be UV-protected and have a minimal irritating effect.  
Formulation and Evaluation of Pulp Devitalization Paste Combination of Jatropha Curcas L. and Piper Crocatum Leaves Extract Damarwati, Vella Lailli; Wahid, Rahmat A Hi; Primasari, Dyani; Harimurti, Sabtanti; Labibah, Lana; Syahrani, Syahrani; Krisridwany, Annisa
Media Farmasi: Jurnal Ilmu Farmasi Vol. 19 No. 2: September 2022
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v19i2.24041

Abstract

Dental caries require operative techniques such as pulp devitalization, but pulp devitalization materials that are often used by dentists have serious adverse effects that need to be considered, such as gingival injury and alveolar bone necrosis. Hence, the aim of the present study was to develop natural ingredients as an alternative to pulp devitalization from a combination of Jatropha curcas (Jatropha curcas L.) and red betel leaf extract (Piper crocatum) in the form of a paste and then conducting physical evaluation tests, Cyclooxygenase-2 (COX-2) tests, and also histopathological picture tests to the sample. The formulation of the pasta sample was carried out by the trituration method.  Formulation I (FI) contained 25% of Jatropha resin, 0.25% red betel leaf extract, and 25% Jatropha resin, 0.5% red betel leaf extract for Formulation II (FII). The paste produced was then evaluated for physical properties which consisted of organoleptic, homogeneity, pH, spreadability, adhesion, and anti-inflammatory power using test animals with COX-2 expression number parameters. The FI and FII treatment groups had met the requirements as paste formula. In the COX-2 expression test, FI has a COX-2 expression percentage value of 0.38% and a COX-2 suppression percentage value of 0.62%, while FII has a COX-2 expression percentage value of 0.59% and a COX-2 expression percentage of 0.59% and suppression of COX-2 of 0.41%. The optimal concentration of the paste formulation is the paste with a combination of 25% jatropha latex and 0.25% red betel leaf extract had been shown to have potential as an alternative to pulp devitalization
Purification of Curcumin Derivate (1,5-bis(4’-hydroxy-3’-methoxyphenyl)-1,4-pentadien-3-on) Using Chromatotron Harimurti, Sabtanti; Fadhilah, Alfan; Widada, Hari; Damarwati, Vella Lailli
Pharmacon: Jurnal Farmasi Indonesia Vol 21, Special Issue 1, 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i0.23593

Abstract

Curcumin derivate with IUPAC name 1,5-bis(4’-hydroxy-3’-methoxyphenyl)-1,4-pentadien-3-on is also known as Gamavuton-0 (GVT-0) reported has an activity as anti-inflammation and anti-cancer. GVT-0 can be synthesized using vanillin and acetone as starting material by aldol condensation. Purification process of GVT-0 after synthesis usually was done using maceration. This method resulting un-pure GVT-0, therefore, another separation technique of Chromatotron was chosen. This research aims to investigate the effectiveness of Chromatotron towards the purity of GVT-0. The study was started by GVT-0 synthesis. The synthesis was using 4.4 mole of vanillin and 1 mole acetone as the raw material. Microwave irradiation was used as the energy source. Isolation of GVT-0 using hot water maceration. Further, the purification of GVT-0 was conducted using Chomatotron. First step of purification using Chomatotron was preparing best ratio between hexane and chloroform as solvent to remove vanillin. Further, the best combination of solvent was used to separate all the vanillin remaining in the bulk of GVT-0. Last step after all vanillin was removed, the GVT-0 remining in the silica was elucidated using chloroform. The purity was evaluated using Melting-point analysis and Thin Layer Chromatography (TLC) with four different mobile phases. Based on the data of melting point and TLC, a pure GVT-0 was obtained. The Chomatotron may be recommended for purification of GVT-0, however this method consumes a lot of organic solvent that may need to be improved in the future with more environmentally process
Enhanced Antioxidant Gel Formulation with Papaya Leaf Extract and Virgin Coconut Oil: Optimization Approach Dyani Primasari Sukamdi; Sophia Farra Ileina; Rima Erviana; Vella Lailli Damarwati; Sabtanti Harimurti; Azura Amid
Borneo Journal of Pharmacy Vol. 9 No. 2 (2026): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v9i2.9317

Abstract

Redness, pigmentation, premature aging, xerosis, and even the risk of cancer can result from excessive exposure to free radicals in the form of ultraviolet (UV) radiation, which can cause skin damage. Antioxidants, including β-carotene, α-tocopherol, ascorbic acid, and flavonoids, are present in papaya (Carica papaya) leaves and Virgin Coconut Oil (VCO). Therefore, these two components may mitigate skin imperfections caused by premature aging. This study aims to formulate and determine the antioxidant activity contained in C. papaya leaf extract gel and VCO. A laboratory-based experimental approach was implemented in this study. Using the infusion method, C. papaya leaves were extracted for 15 minutes to initiate the gel formation. The C. papaya leaf extract gel with VCO was divided into five formulations, with varying amounts of each ingredient. Organoleptic, homogeneity, viscosity, pH, spreadability, and antioxidant activity tests, conducted using the DPPH method, are included in the preparation testing process. The antioxidant activity test of C. papaya leaf extract gel with VCO in each formula yielded values of 91.32 ppm, 121.21 ppm, 80.19 ppm, 67.04 ppm, and 55.31 ppm, respectively. The results indicated that the quality of the gel preparation and the IC50 value of the C. papaya leaf extract gel were influenced by variations in VCO concentration.
Co-Authors Aji Winanta Andy Eko Wibowo Azura Amid Chaessy Yori Anggraini Dewinda, Zulfa Sekar Dyani Primasari Sukamdi Erlangga Jun Prasetya Fadhilah, Alfan Fajarani, Rizky Anita Hari Widada, Hari Hasna Nuansa Sasadara Ingenida Hadning Khrisna Heryanti Krisridwany, Annisa Kunniya Amany Kurniawan, Muhammad Fariez Labibah, Lana Maura Shavira Alamsyah Moch. Saiful Bachri Muhammad Fariez Kurniawan Muhammad Thesa Ghozali Neva Valencia Eka Apriliana Ningrum, Dhecella Winy Cintya Nita Fajar Maharani Nurul Maziyyah Pinasti Utami, Pinasti Pramitha Esha Nirmala Dewi Primasari, Dyani Prita Anggraini Kartika Sari Putri Arditya Radhwa Fauztina Rahajeng, Bangunawati Rahmat A. Hi Wahid Rima Erviana Rizka Wahyu Septiasih Sabeta, Meilidya Vani Sabtanti Harimurti Sabtanti Harimurti Sabtanti Harimurti, Sabtanti Salmah Orbayinah Sayidah Aulia Ul Haque Sophia Farra Ileina SYAHRANI SYAHRANI Wahid, Rahmat A Hi Wahyu Widyaningsih Wardah Dwi Latifah Zaki Tiffani Lazuardian Zelmi Dwi Novita Zhafira As Syafa