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PENGARUH PEMBERIAN KOMBINASI OBAT DUTASTERIDE DAN TAMSULOSIN TERHADAP KADAR PSA (PROSTATE SPECIFIC ANTIGEN) PADA PASIEN BPH (BENIGN PROSTATIC HYPERPLASIA) DI RSUD PROVINSI NUSA TENGGARA BARAT salsabila, safira; Maulana, Akhada Maulana; Nandana, Pandu Ishaq; Wedayani, AA Ayu Niti
Jurnal Kedokteran Vol 9 No 1 (2020): Jurnal Kedokteran Vol 9 No 1 2020
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v9i1.405

Abstract

Latar belakang: Benign Prostatic Hyperplasia (BPH) merupakan tumor jinak yang biasa dijumpai pada 1 dari 3 pria yang berusia lebih dari 50 tahun. Sedangkan Prostate Specific Antigen (PSA) adalah protein yang dihasilkan oleh kelenjar prostat yang bersifat organ spesifik dan diperiksa pada semua pasien BPH untuk mengetahui perjalanan penyakit BPH. Penggunaan obat dutasteride pada BPH dapat menghambat perubahan testosteron menjadi dihidrotestosteron serta dapat menekan pertumbuhan prostat karena obat ini termasuk dalam golongan inhibitor 5 alfa reduktase. Tamsulosin termasuk dalam golongan obat antagonis reseptor alfa 1 yang dapat merelaksasikan tonus otot polos kelenjar prostat dan leher buli-buli. Metode: Penelitian ini menggunakan desain penelitian komparatif dengan pendekatan eksperimental dan metode pengambilan data dengan pengukuran berulang (pre test – post test field trial). Pengambilan data dilakukan di Instalasi Rawat Jalan Poliklinik Bedah Urologi dan Instalasi Rekam Medis RSUD Provinsi NTB pada periode waktu Oktober 2019 sampai dengan Desember 2019. Hasil: Dari 32 responden yang dilakukan pemeriksaan PSA awal dan akhir didapatkan rata-rata kadar PSA awal terbanyak pada kelompok <4 ng/ml dan rata-rata kadar PSA akhir terbanyak pada kelompok <4 ng/ml. Rata-rata responden berasal dari kelompok usia 61-69 tahun. Berdasarkan uji hipotesis menggunakan uji paired sample T test diperoleh nilai p = 0,035 (p < 0,05) menunjukkan terdapat perubahan kadar PSA pada pasien BPH yang sudah diberi kombinasi obat dutasteride dan tamsulosin. Kesimpulan: Terdapat perubahan kadar PSA pada pasien BPH yang sudah diberi terapi menggunakan kombinasi obat dutasteride dan tamsulosin di RSUD Provinsi Nusa Tenggara Barat.
Characteristics of Patients with Non-Malignant Pleural Effusion in dr. Zainoel Abidin Hospital Banda Aceh in 2019 Putra, Teuku Romi Imansyah; Maya, Price; Hasan, Maryatun; Pranata, Agung; Salsabila, Safira; Sariningrum, Hesti Ariandani
Jurnal Penyakit Dalam Indonesia Vol. 9, No. 1
Publisher : UI Scholars Hub

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Abstract

Introduction. Pleural effusion occurs when there is a pathological process causing fluid to accumulate in the pleural cavity. Pleural effusion is still the main cause of respiratory distress and can also be caused by many diseases either from pleural, lungs, or even extrapulmonary problems. The morbidity and mortality of this condition are directly associated with the underlying causes. The aim of this study is to investigate the profile of the patients, etiology, location, fluid characteristics, comorbidities, and also the bacteria pattern of non-malignant pleural effusion. Methods. This is a retrospective descriptive study thatused patient’s medical records from January to December 2019 in Zainoel Abidin Hospital, Banda Aceh as the source of data for this study. Results. There were 118 patients with non-malignant pleural effusion from January to December 2019. In this study, it was found that the highest gender was male (66.9 %) and in the age group of 46-55 and >65 years old in male, and 56-66 years old in female. The most frequent etiology of non-malignant pleural effusion was pneumonia. The majority (72.9%) of pleural effusion were exudate and mostly happened in the right lung (53.4%). Comorbidities were found in 104 patients and the main comorbiditywas tuberculosis (11.3%). The result of the pleural fluid culture test showed that there were 33 samples with positive results. Staphylococcus hominis was the bacteria found in most of the isolates (22.9%).Conclusion. Non-malignant pleural effusions are generally exudates with Staphylococcus hominis being the most common bacterial growth
Peran kepercayaan konsumen memediasi electronic word of mouth terhadap keputusan pembelian pada pengguna market place Lazada Khatimah, Husnul; Salsabila, Safira
Jurnal STEI Ekonomi Vol 32 No 2 (2023)
Publisher : Bagian Pengelolaan Jurnal dan Penerbitan - Sekolah Tinggi Ilmu Ekonomi Indonesia (BPJP - STIE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36406/jemi.v32i02.891

Abstract

The purpose of this study was to examine the impact of EWOM on brand trust purchasing decisions of Lazada consumers. The variables examined in this study are EWOM, brand trust, and purchase decisions. Sample size drawn by distributing 100 respondents. The data collection method in this study was by questionnaire. The analytical technique used is MRA regression analysis. Based on the results of the analysis, EWOM has a positive and significant impact on consumer trust, EWOM has a positive and significant impact on purchasing decisions, and consumer trust has a positive and significant impact on purchasing decisions. It has made a significant impact and the role of consumer trust has been made clear. Key role in his EWOM mediation in marketplace product purchase decisions. Lazada in Bekasii city. Positive EWOM is one of our efforts to increase consumer confidence. EWOM has a significant impact on trust in product purchasing decisions. A positive EWOM encourages consumers to make immediate purchase decisions.
CHECKS AND BALANCES DALAM MEKANISME PEMAKZULAN TERHADAP PRESIDEN ATAU WAKIL PRESIDEN MENURUT PERSPEKTIF HUKUM TATA NEGARA Salsabila, Safira; Suciana, Suciana; Indradjaja, Nobella; Chamdani, Chamdani
Jurnal Ilmu Hukum Wijaya Putra Vol 2 No 2 (2024): September
Publisher : Fakultas Hukum Universitas Wijaya Putra

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38156/jihwp.v2i2.197

Abstract

Terdapat perubahan mekanisme pasca amandemen UUD 1945 tentang pemakzulan Presiden atau Wakil Presiden. Pasca amandemen, proses pemakzulan dapat diinisasi oleh DPR kepada MK dengan menyertakan dugaan kuat atas unsur pelanggaran yang telah dilakukan oleh Presiden atau Wakil Presiden. Setelah itu, MK akan membuat keputusan yang nantinya akan dirapatkan melalui sidang parlemen MPR. Melihat mekanisme pemakzulan diatas, muncul pertanyaan baru, apakah mekanisme ini sesuai dengan supremasi hukum tata negara? Maka, penelitian ini ditulis untuk menemukan mekanisme pemakzulan yang dijabarkan dalam UUD 1945 menurut supremasi hukum tata negara, dengan berfokus kepada fungsi checks and balances melalui metode kualitatif. Hasil penelitian ini menunjukkan bahwa mekanisme pemakzulan tidak berjalan sesuai dengan UUD 1945 dikarenakan adanya mekanisme politik. Maka, dapat dikatakan proses checks and balances belum berlangsung secara berimbang karena putusan MK terhadap dakwaan masih tidak eksplisit maupun mengikat bagi MPR dan UUD 1945.
CHECKS AND BALANCES IN THE IMPEACHMENT MECHANISM OF THE PRESIDENT OR VICE PRESIDENT FROM A CONSTITUTIONAL LAW PERSPECTIVE Salsabila, Safira; Suciana, Suciana; Indradjaja, Nobella; Chamdani, Chamdani
EQUALEGUM International Law Journal Volume 2, Issue 3, 2024
Publisher : SYNTIFIC

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Abstract

Background. There are changes to the mechanism following the amendment of the Indonesian 1945 Constitution, regarding the President's or Vice President's impeachment. After the amendment, the impeachment process can be initiated by the House of Representatives to the Constitutional Court by including strong allegations of violations committed by the President or Vice President. After that, the Constitutional Court will make a decision which will later be discussed in a parliamentary session of the People’s Consultative Assembly. Looking at the impeachment mechanism above, a new question arises as to whether this mechanism is by the supremacy of constitutional law. Research Method. This research is written to find the impeachment mechanism outlined in the 1945 Constitution according to the supremacy of constitutional law, by focusing on the function of checks and balances through qualitative methods. Findings. The results of this research show that the impeachment mechanism is not by the 1945 Constitution due to the existence of political mechanisms. Conclusion. The checks and balances process has not taken place in a balanced manner because the Constitutional Court's decision on the indictment is inexplicit or binding on both the People’s Consultative Assembly and the 1945 Constitution.
The Analysis Study of Diagnostic Performance and Accuracy of Panoramic Radiography to Screen Bone Mineral Density in Woman: A Comprehensive Systematic Review Audhi, Muhammad Riefki; Salsabila, Safira
The Indonesian Journal of General Medicine Vol. 2 No. 2 (2024): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/88g24546

Abstract

Background: Bone mineral density (BMD) is a crucial measure of bone health, providing essential information for assessing the risk of fractures and other bone-related conditions. Panoramic radiography, commonly used in dental practice, presents a potential alternative for BMD screening. This systematic to evaluate the effectiveness of panoramic radiography in detecting BMD based on literatures of the last 10 years Methods: The study adhered to PRISMA 2020 standards, examining English literature from 2014 to 2024. It excluded editorials, reviews from the same journal, and submissions without a DOI. PubMed, SagePub, SpringerLink, and Google Scholar were utilized as literature sources. Result: Initially retrieving 360 articles from online databases (PubMed, SagePub, SpringerLink and Google Scholar) eight relevant papers were selected after three rounds of screening for full-text analysis. Conclusion: Panoramic radiographs, including MI, MCI, and MCW, are valuable tools for screening bone mineral density (BMD) and detecting osteoporosis in women. Panoramic radiographs are effective in detecting osteoporosis, especially in postmenopausal women.
Pembuatan Pupuk Organik Dari Limbah Kotoran Hewan Dan Tumbuhan Bersama Kelompok Tani Dan Masyarakat Desa Dalam Mengoptimalkan Hasil Pangan Nurcahyani, Divka; F, Dyah Ayu; S, Della Nur; Amanda, Verlina Tasya; Khairani, Syafira; M, Prilianti Tiurida; Salsabila, Safira; Fadhilah, Salva; M, Akhrianil Hami; Sholehah, Ummatus; S, Reyhan Achmad Dani
Jurnal Pengabdian Sosial Vol. 2 No. 2 (2024): Desember
Publisher : PT. Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/5a4eyr85

Abstract

Tujuan dari kegiatan ini adalah memberikan pelatihan yang disertai dengan praktik pembuatan pupuk organik dari kotoran hewan dan tumbuhan di Desa X, Kecamatan X, Kabupaten X. Pupuk organik dapat disebut juga dengan pupuk kompos yang berasal dari sisa tanaman dan kotoran hewan yang telah mengalami proses pelapukan. Bahan pembuatan pupuk organik pada umumnya menggunakan kotoran hewan seperti sapi atau kambing. Keunggulan dari pupuk organik ini adalah ramah lingkungan, dan dapat meningkatkan kesuburan tanah dengan memperbaiki kerusakan fisik tanh akibat pemakaian pupuk anorganik secara berlebihan pada saat sebelumnya. Kelompok Tani Desa X merupakan kelompok tani yang beternak sapi dan kambing, sekaligus melakukan penanaman padi di sawah, bahkan tidak hanya satu jenis tumbuhan saja, tetapi juga ada beberapa jenis seperti tumbuhan jagung, sargum, dan juga jenis kacang-kacangan lainnya. Limbah kotoran ternak yang dihasilkan dari kelompok tani tersebut belum diolah secara maksimal untuk digunakan sebagai pupuk organik pada lahan pertanian. Selama ini, petani masih mengandalkan pupuk kimia sebagai sumber utama pupuk. Dampak dari penggunaan pupuk kimia secara berkepanjangan dapat menyebabkan kerusakan fisik pada tanah. Oleh karena itu dengan adanya pelaksanaan program pelatihan kepada kelompok tani ini dengan tujuan untuk menambah pengetahuan tentang pembuatan pupuk organik dengan bahan dasar kotoran hewan dan tumbuhan. Kegiatan sosialisasi dan praktik pembuatan pupuk organik ini sudah dilaksanakan bersama kelompok tani. Hasil pupuk organik yang diperoleh nantinya diharapkan dapat diaplikasikan pada lahan pertanian tersebut.
Modelling Consumer Price Index Effect on 10-year US Treasury Bond Yields using Least Square Spline Approach Widiyanti, Julia; Salsabila, Safira; Harsanti, Dwika Maya; Amelia, Dita; Rifada, Marisa
JTAM (Jurnal Teori dan Aplikasi Matematika) Vol 9, No 4 (2025): October
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jtam.v9i4.33020

Abstract

Inflation measured by the Consumer Price Index (CPI) is a critical indicator in the government bond market that directly affects the yields of long-term securities such as the 10-year US Treasury Bond. This study is an explanatory quantitative study that aims to examine the complex dynamics of this relationship using the nonparametric least square spline method. The analysis uses monthly CPI data from FRED and 10-year US Treasury bond yield data from Investing.com for the period 2013-2025. This method divides the data into simple polynomial segments that are smoothly connected at transition points (knots), enabling the modelling of nonlinear patterns without assuming an initial curve shape. The analysis results indicate that a first-degree polynomial spline model (piecewise linear) with three knots successfully represents the bond yield response to inflation shocks with R^2 = 86.48%. Model segmentation identified four regimes: (1) Post-crisis recovery phase, with a negative relationship driven by Fed monetary stimulus suppresing yields despite initial inflation emergence; (2) Policy normalization phase, with a positive relationship aligned with monetary tightening in response to moderate inflation; (3) During the COVID-19 pandemic, a negative relationship due to a surge in demand for safe-haven bonds despite rising inflation; (4) Post-pandemic, the relationship turned positive again following the Fed’s aggressive monetary tightening in response to high global inflation. These findings highlight the urgency of regime-based monitoring for investors and policymakers, while contributing concretely to SDG 8 (decent work and economic growth) through the facilitation of appropriate interest rate policies for sustainable macroeconomic stability, and supporting SDG 9 (industry, innovation, and infrastructure) through the identification of inflation patterns that strengthen shock-resistant infrastructure investment planning and financial innovation during turbulent economic transitions.
MANAJEMEN SUMBER BELAJAR PENDIDIKAN DAN SISTEM INFORMASI MANAJEMEN PENDIDIKAN Hadiwijaya; salsabila, safira; Muh.Arif Hidayatullah; Sartika Sari; Anisa Safitri; Sulkifli
As-Sulthan Journal of Education Vol. 1 No. 4 (2025): Mei
Publisher : As-Sulthan Journal of Education

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Abstract

Educational management is an imperative component in achieving effective and efficient learning goals. One important aspect in educational management is classroom and student management, which plays a direct role in creating a conducive learning environment. This article discusses the concept, principles, and application of classroom management and student management in the context of formal education. This study uses a descriptive qualitative approach with literature studies as a method of collecting information. The results of the study indicate that effective classroom management includes spatial planning, time management, and clear rule enforcement, while student management involves understanding individual characteristics, providing motivation, and an individual approach to guidance. The conclusion of this study confirms that the synergy between classroom management and students can improve the quality of learning and encourage the achievement of ideal learning outcomes.