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Program Lampionisasi Jalan Dusun Dan Pengembangan Produk Umkm Dalam Peningkatan Kreativitas Masyarakat Di Dusun Pundung Banaran Galur Kulon Progo Wijayanto, Ari; Ilmi, Annisa Nurul; Hidayat, Putri Lathifah; Ma’rufah, Khairimatul; Iqmalia, Nindya Fani; Wardani, Pranesti Sanditiya; Darmawan, Muhammad Fahmi; Pratama, Muhammad Wahyu Diaz; Sandiaji, Alwi Farhan; Eryonaristobobamartyajati, Dhymasion Gusti; Suranto, Suranto
Prosiding Seminar Nasional Program Pengabdian Masyarakat Vol. 7 No. 1 (2024): SIBISA - Seminar Nasional Pengabdian kepada Masyarakat UMY 2024
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/ppm.71.1248

One of the problems in Pundung Hamlet is the lack of street lighting, so the KKN 032 Program in Pundung Hamlet aims to solve the problem of street lighting with solar-powered PJU lights to increase security. In addition, teaching Family Medicinal Plants (TOGA) in elementary schools to add insight to children in elementary schools to add insight to children, socialization of Digital Marketing and UMKM rebranding, and socialization of Trap Barrier to increase agricultural yields. Activities took place January 11 - February 11, 2024, focusing on improving community welfare, knowledge, and skills. The methods used include preparation of work plans, program implementation, and evaluation. The survey results showed problems with street lighting and potential accidents. The solution is the use of solar-powered PJU lights. In addition, there are TOGA teaching activities in elementary schools, socialization of Digital Marketing and UMKM rebranding, and Trap Barrier socialization for farmers. Hopefully, this program will improve the welfare, business knowledge, and image of Pundung Hamlet, involving active participation of students in community development evenly and thoroughly.

Gut Microbiome Education through Game-Based Learning for MA Sabilarrasyad Samarinda Students Yuliatin, Ervinda; Hariani, Nova; Patang, Fatmawati; Budiman, Budiman; Kurniati, Reni; Hasibuan, Febry Rahmadhani; Ilmi, Annisa Nurul
Jurnal SOLMA Vol. 14 No. 1 (2025)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v14i1.16861

Background: Metode Game-Based Learning menjadi alternatif pembelajaran yang memotivasi siswa SMA dalam belajar, sehingga dapat menstimulasi siswa untuk merefleksikan hasil belajar. Metode ini dapat diterapkan kepada siswa SMA agar memahami konsep Gut Microbiome dengan mudah yang bermanfaat untuk menjaga kesehatan usus siswa. Kegiatan ini bertujuan untuk mengedukasi peran penting Gut Microbiome melalui permainan kartu “Gutsy Game”. Metode: Edukasi Gut Microbiome diikuti oleh 59 siswa MA Sabilarrasyad Samarinda, melalui 4 tahapan yaitu Pre-test, pemaparan materi, praktek Gutsy Game, Post-test dan evaluasi kegiatan. Nilai pre-test dan post-test diperoleh dari pertanyaan seputar materi Gut Microbiome sedangkan evaluasi kegiatan diukur menggunakan kuisioner yang ditentukan berdasarkan Indeks Kepuasan Kegiatan. Hasil: Pemahaman siswa tentang konsep Gut Microbiome meningkat 20%, materi informatif (62%), relevan (70%), memotivasi pola hidup sehat (83%), dan pelaksanaan kegiatan memuaskan (70%). Berdasarkan Indeks Kepuasaan, siswa menilai kegiatan edukasi baik (83,3), menunjukkan metode permainan Gutsy Game berhasil menarik minat siswa untuk belajar. Kesimpulan: Gutsy Game dapat digunakan untuk memahami konsep dasar keseimbangan Gut Microbiome dan meningkatkan minat belajar pada siswa MA Sabilarrasyad Samarinda.

PERAN NUTRISI DALAM MODULASI GEN INFLAMASI PADA KERUSAKAN MUKOSA LAMBUNG AKIBAT NSAID: SEBUAH PENDEKATAN NUTRIGENOMIK Prayoga, Adhimas; Ilmi, Annisa Nurul
BIOPROSPEK: Jurnal Ilmiah Biologi Vol 17 No 1 (2025): BIOPROSPEK: Jurnal Ilmiah Biologi
Publisher : Jurusan Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/qtab7a55

Obat antiinflamasi nonsteroid (NSAID) merupakan terapi yang umum digunakan, khususnya pada kelompok lansia, namun penggunaannya dapat menyebabkan gangguan mukosa lambung yang dipicu oleh penghambatan enzim COX-1 dan peningkatan stres oksidatif. Artikel yang dianalisis merupakan penelitian primer dari tahun 2014 hingga 2024 dengan desain in vivo, in vitro, atau observasional yang relevan dengan topik yang dikaji berdasarkan hasil utama, ekspresi gen terkait, dan mekanisme molekuler. Hasil sintesis dari sembilan studi utama menunjukkan bahwa senyawa seperti omega-3 (EPA dan DHA), astaxanthin, polifenol, dan komponen aktif dari walnut dan Gardenia jasminoides mampu memberikan perlindungan mukosa melalui aktivasi jalur molekuler Nrf2/HO-1 dan AMPK/SIRT1, serta menekan jalur inflamasi NF-κB dan COX-2. Namun, konsumsi lemak jenuh tinggi dapat memperparah kondisi mukosa dengan meningkatkan IL-17A dan menurunkan gen pelindung seperti TLR4, Ocln, dan Nr1h4. Hasil studi ini menunjukkan bahwa pola makan dan komponen nutrisi tertentu mampu memengaruhi ekspresi gen dan jalur molekuler yang berperan dalam menjaga kesehatan mukosa lambung. Temuan ini mendukung potensi pendekatan nutrigenomik sebagai strategi preventif dan pendukung terapi yang lebih aman untuk mengurangi risiko gangguan saluran cerna akibat penggunaan NSAID dalam jangka panjang.

Allium spp. as a Source of Bioactive Antibacterials: A Review of Compounds, Mechanisms, and Effectiveness Hasibuan, Febry Rahmadhani; Pujiyanti, Aloysia Sri; Ilmi, Annisa Nurul; Hariani, Nova
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 10, No 2 (2025): June 2025
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v10i2.10858

Allium spp. has long been recognized for its diverse therapeutic benefits, particularly as a natural source of antibacterial agents. Various bioactive compounds found in Allium spp., such as allicin, diallyl disulfide, ajoene, and quercetin, have demonstrated significant antimicrobial activity against both gram-positive and gram-negative bacterial pathogens. Research on the mechanisms of antibacterial action of these compounds reveals that they work by disrupting bacterial cell membranes, inhibiting protein synthesis, and interfering with bacterial metabolism. This literature review aims to examine existing studies on the antibacterial potential of Allium spp., reviewing the bioactive compounds involved, their mechanisms of action, and their effectiveness in inhibiting bacterial growth, including antibiotic-resistant pathogens such as methicillin- resistant Staphylococcus aureus (MRSA) and Escherichia coli. The findings of this review indicate that while their effectiveness may vary depending on the specific compound and form of application, Allium spp. shows considerable promise as a natural alternative for combating bacterial infections and addressing the growing issue of antibiotic resistance. This article provides deeper insights into the relevance and potential of Allium spp. in the development of antimicrobial therapies based on natural sources through a literature-based approach.

Potensi Antioksidan Kombucha Bunga Telang (Clitoria ternatea) sebagai Minuman Fungsional Pujiyanti, Aloysia Sri; Ilmi, Annisa Nurul
Jurnal Ilmiah Pangan Halal Vol. 7 No. 2 (2025): Jurnal Ilmiah Pangan Halal
Publisher : Universitas Djuanda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30997/jiph.v7i2.19537

Kombucha yang difermantasikan dari bunga telang (Clitoria ternatea) merupakan minuman fungsional dengan potensi antioksidan tinggi dan nilai tambah kesehatan. Beberapa penelitian melaporkan bahwa bunga telang kaya akan antosianin dan flavonoid, senyawa fenolik yang efektif menetralisir radikal bebas penyebab penyakit degeneratif seperti kanker, penyakit jantung, diabetes, dan penuaan dini serta mempertahankan mutu produk pangan. Metode tinjauan pustaka (literature review) menggunakan metode yang bersifat deskriptif-kualitatif dengan tujuan mengkaji potensi antioksidan kombucha berbasis bunga telang (Clitoria ternatea) sebagai minuman fungsional. Beberapa penelitian melaporkan aktivitas antioksidan yang diukur menggunakan metode DPPH pada kombucha bunga telang dengan rentang waktu fermentasi 8 hingga 20 hari menghasilkan aktivitas antioksidan yang tinggi dengan IC50 15%-19% dan % Inhibisi 70%-89%. Sehingga dapat disimpulkan dengan aktivitas antioksidan yang tinggi memiliki potensi sebagai minuman fungsional. Hasil review ini diharapkan dapat digunakan sebagai rujukan untuk penelitian lebih lanjut untuk mengetahui manfaat langsung dan kandungan dari kombucha bunga telang (Clitoria ternatea).

Ethnobotanical, Phytochemical, and Pharmacologies Aspect of Kaempferia rotunda L. as a Local Herbal Plant with Global Potential: A Review Pujiyanti, Aloysia Sri; Kusuma, Ratna; Ilmi, Annisa Nurul; Hasibuan, Febry Rahmadhani
Biocaster : Jurnal Kajian Biologi Vol. 5 No. 3 (2025): July
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/biocaster.v5i3.462

Kaempferia rotunda L., also known as kunci pepet, is a local herbal plant with global potential traditionally used in various medicinal practices across Southeast Asia. This review summarizes the ethnobotanical, phytochemical, and pharmacological aspects of Kaempferia rotunda L., to explore its applications in modern medicine. Ethnobotanically, its rhizome has been widely utilized for treating digestive disorders, inflammation, and wound healing. Phytochemical studies reveal that Kaempferia rotunda L., contains flavonoids, alkaloids, phenols, and terpenoids, contributing to its biological activities. Several studies have demonstrated significant anti-inflammatory, antibacterial, antioxidant, and anticancer properties. With the increasing demand for natural-based therapies, further exploration of their active compounds and mechanisms of action is highly relevant. This review aims to provide a broader insight into the pharmaceutical potential of Kaempferia rotunda L., and encourage further research for the development of evidence-based herbal medicine.

Immunomodulatory and Antidiabetic Potential of Kratom (Mitragyna speciosa) on Animal Models: Potentials and Future Research Ilmi, Annisa Nurul; Hasibuan, Febry Rahmadhani; Pujiyanti, Aloysia Sri; Kurniati, Reni
Biocaster : Jurnal Kajian Biologi Vol. 5 No. 3 (2025): July
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/biocaster.v5i3.463

Kratom (Mitragyna speciosa) has been traditionally used for its analgesic and stimulant properties. Recent preclinical studies suggesting its potential as an anti-inflammatory and antidiabetic agent. A comprehensive search of PubMed, ScienceDirect, and Google Scholar (2010-2024) using keywords “Kratom”, “inflammation”, and “diabetes” identified 82 studies. After applying inclusion criteria (original research, English/Bahasa Indonesia, in vivo animal models investigating anti-inflammatory/antidiabetic effects) and excluding reviews, in vitro studies, and conference abstracts, 14 studies comprising 9 key articles on the pharmacological activities of Kratom were analyzed. Dosages ranged from 0,5 mg/g to 500 mg/kg across various extraction methods and treatment durations. Studies show that Kratom extracts can inhibit pro-inflammatory cytokines (IL-1β, TNF-α) via NF-κB, COX-2, and MAPK/ERK pathways. In diabetic models, Kratom reduced blood glucose levels by 15-45%, improved glucose tolerance, and enhanced antioxidant status. Aqueous and ethanolic extracts showed comparable efficacy, with optimal effects observed at 100-200 mg/kg doses. Despite these findings, safety concerns remain regarding toxicity, dependence, and drug interactions. Further toxicological studies and clinical trials are essential to validate its therapeutic potential. This review highlights the need for comprehensive research and regulatory evaluation to support the safe medicinal use of Kratom.

KARAKTERISASI MORFOLOGI DAN ANALISIS LITERATUR PERAN VEKTOR KUTU PUTIH (PSEUDOCOCCIDAE) PADA TANAMAN HIAS DI LINGKUNGAN KAMPUS UNIVERSITAS MULAWARMAN: MORPHOLOGICAL CHARACTERISATION AND LITERATURE ANALYSIS OF THE ROLE OF WHITEFLY VECTORS (PSEUDOCOCCIDAE) ON ORNAMENTAL PLANTS IN THE CAMPUS ENVIRONMENT OF MULAWARMAN UNIVERSITY Hasibuan, Febry Rahmadhani; Khotizah, Laraz Nur; Butar, Marentina Kirana Butar; Hariyanti, Mutina; Putri, Rania Sakanti Arindra; Veraresa, Ray Herry; Widya Syahfitri; Ilmi, Annisa Nurul; Pujiyanti, Aloysia Sri
Jurnal HPT (Hama Penyakit Tumbuhan) Vol. 13 No. 3 (2025)
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jurnalhpt.2025.013.3.2

Kutu putih (Pseudococcidae) merupakan hama penting yang menyebabkan kerusakan fisiologis dengan mengisap getah dari floem dan juga bertindak sebagai vektor patogen tumbuhan, termasuk virus, bakteri, dan jamur. Tujuan studi ini adalah untuk mengidentifikasi spesies kutu putih pada tanaman hias dan mengevaluasi potensi mereka dalam menularkan patogen di lingkungan tropis. Sampel dikumpulkan dari tiga spesies tanaman hias, yaitu Agave americana, Heptapleurum arboricola, dan Colocasia esculenta L, di Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) Universitas Mulawarman. Penelitian ini menggunakan desain deskriptif-eksploratif untuk mengidentifikasi spesies kutu putih dan menganalisis potensinya sebagai vektor patogen pada tanaman hias. Pengambilan sampel dilakukan secara purposif dengan kriteria inklusi sebagai berikut: (1) tanaman hias yang menunjukkan gejala infestasi kutu putih (misalnya koloni berwarna putih, daun menguning, atau nekrosis), (2) tanaman yang termasuk dalam tiga spesies target (Agave americana, Heptapleurum arboricola, dan Colocasia esculenta L.), dan (3) lokasi tumbuh yang terpapar kondisi lingkungan alami (tidak dalam rumah kaca atau perlakuan pestisida). Identifikasi morfologis menunjukkan dua spesies kutu putih dominan, Paracoccus marginatus dan Pseudococcus cryptus, yang ditemukan pada fase nimfa betina dan dewasa. Fase instar II dan III melibatkan aktivitas makan dan pengeluaran madu, yang memfasilitasi penularan patogen melalui mekanisme mekanis dan biologis. Pengeluaran ini juga menciptakan kondisi ideal untuk kolonisasi patogen sekunder, seperti spesies Fusarium dan Capnodium. Kondisi iklim tropis yang hangat dan lembap memperkuat vektorisasi patogen oleh kutu putih. Temuan ini memperkuat gagasan bahwa kutu putih memainkan peran epidemiologis yang signifikan dalam penyebaran penyakit tanaman hias, memberikan dasar penting untuk strategi pengendalian biologis dan pemantauan penyakit di lingkungan tropis.

Improving Students’ Speaking Skills through Cooperative Learning in Vocational School Context Ilmi, Annisa Nurul
Jurnal Ilmu Sosial dan Humaniora Vol. 1 No. 4 (2023): Juni (Jurnal Ilmu Sosial dan Humaniora)
Publisher : CV Insan Kreasi Media

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57248/jishum.v1i4.150

Speaking is one of important language skills that should be mastered by vocational school students in order to be able to compete in 21st century. It is of the most frequently utilized and most challenging language abilities. The aim of the study is to improve students’ speaking skills through cooperative learning. It categorizes as action research study consisting of plan, implementation, observation, and reflection adapted from Kemmis, McTaggart, and Nixon. Thirty six students who were in the tenth grade of Public Vocational School 7 Yogyakarta majoring tourism participated in the study. They consisted of 33 females and 3 males. Two cycles and eleven meetings were applied during the research. The data were collected through observation, interview, questionnaire, and assessment. The findings shows that the students’ speaking skills improved during the teaching and learning process through some activities such as using classroom English; applying cooperative learning methods: two stray two stay, think-pair-share, numbered heads together, and inside outside circle methods; encouraging the students to be aware with their performance and be able to do self-correction as well as giving feedback to other performance; adapting the learning materials to suit students’ needs; and motivating students to bring a dictionary and install electronic dictionary in their mobile. The students speaking scores before and after implementing cooperative learning show significant improvement from the total mean of the class 482.5 to 512.5. To sum up, cooperative learning is successful in improving the students’ speaking skills. The results of the research provide useful insight for teachers considering improving language skills by using cooperative learning. Keywords: speaking skills, cooperative learning, action research, vocational school

Allium spp. as a Source of Bioactive Antibacterials: A Review of Compounds, Mechanisms, and Effectiveness Hasibuan, Febry Rahmadhani; Pujiyanti, Aloysia Sri; Ilmi, Annisa Nurul; Hariani, Nova
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 10, No 2 (2025): June 2025
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v10i2.10858

Allium spp. has long been recognized for its diverse therapeutic benefits, particularly as a natural source of antibacterial agents. Various bioactive compounds found in Allium spp., such as allicin, diallyl disulfide, ajoene, and quercetin, have demonstrated significant antimicrobial activity against both gram-positive and gram-negative bacterial pathogens. Research on the mechanisms of antibacterial action of these compounds reveals that they work by disrupting bacterial cell membranes, inhibiting protein synthesis, and interfering with bacterial metabolism. This literature review aims to examine existing studies on the antibacterial potential of Allium spp., reviewing the bioactive compounds involved, their mechanisms of action, and their effectiveness in inhibiting bacterial growth, including antibiotic-resistant pathogens such as methicillin- resistant Staphylococcus aureus (MRSA) and Escherichia coli. The findings of this review indicate that while their effectiveness may vary depending on the specific compound and form of application, Allium spp. shows considerable promise as a natural alternative for combating bacterial infections and addressing the growing issue of antibiotic resistance. This article provides deeper insights into the relevance and potential of Allium spp. in the development of antimicrobial therapies based on natural sources through a literature-based approach.

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