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Journal : Borneo Journal Of Pharmascientech

Perbandingan tingkat kepatuhan pasien hipertensi yang diberikan konseling dengan alat bantu pesan pengingat dan brosur Akhmad Junaidi; Herliana Dewi; Hendrya Legenda; Dita Ayulia Dwi Sandi; Satrio Wibowo Rahmatullah; Karunita Ika Astuti
BORNEO JOURNAL OF PHARMASCIENTECH Vol 5 No 1 (2021): Borneo Journal of Pharmascientech
Publisher : Sekolah Tinggi Ilmu Kesehatan Borneo Lestari Banjarbaru

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v5i1.374

Abstract

Hypertension is a condition with blood pressure in 140/90 > mmHg. Medication compliance in hypertension patient can control blood pressure. Complience can improve with counseling and use tools of counselling. The aim of this study was to know the effect of counselling with the tools i.e an SMS reminder and brochure for compliance of hypertension patient. The study was observational analytical study by using the instrument of Adherence Morisky questionnaire Modified Scale (MMAS-8) to measure the level of compliance of the patient. Patients (n=61) were divided into 3 groups i.e the patients were only given counselling, given counselling and sms reminder (2 weeks), given counseling and brochures. Results of this study was compliance levels respectively high, medium and low were 21.74%; 43.48% and 34.78% (group counselling), 46.67%; 13.33% and 40% (group counseling and sms reminder) and 39.13%; 34.78% and 26.09% (group counseling and brochures). There was effect of counselling with an SMS reminder and brochure for compliance of hypertension patient (sig. 0,000) and there was no difference for compliance of hypertension patients in patients who given counseling with an SMS reminder or brochure (sig 0,497)
UJI POTENSIASI EFEK SEDATIF-HIPNOTIK EKSTRAK ETANOL KANGKUNG AIR (Ipomoea aquatic) ASAL GAMBUT KALIMANTAN SELATAN Potential Test Of Sedative-Hypnotic Effect Extract Ethanol Ipomoea Aquatica Form Gambut, South Kalimantan. Karunita Ika Astuti; Fitriyanti Fitriyanti
BORNEO JOURNAL OF PHARMASCIENTECH Vol 2 No 2 (2018): Borneo Journal of Pharmascientech
Publisher : Sekolah Tinggi Ilmu Kesehatan Borneo Lestari Banjarbaru

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Abstract

UJI POTENSIASI EFEK SEDATIF-HIPNOTIK EKSTRAK ETANOL KANGKUNG AIR (Ipomoea aquatic) ASAL GAMBUT KALIMANTAN SELATAN Potential Test Of Sedative-Hypnotic Effect Extract Ethanol Ipomoea Aquatica Form Gambut, South Kalimantan. Karunita Ika Astuti* dan Fitriyanti STIKES Borneo Lestari, Kelapa Sawit 8 Bumi Berkat, Banjarbaru, Indonesia *karunitaika@gmail.com ABSTRAK Pengobatan Sedatif-hipnotik menggunakan golongan obat depresan Susunan Saraf Pusat (SSP) yang relatif tidak selektif namun obat dari golongan ini jika digunakan berkepanjangan dapat bersifat toksik dan menyebabkan kematian. Kangkung air (Ipomoea aquatic) memiliki efek antioksidan yang baik. Tujuan dari penelitian ini adalah untuk mengetahui kandungan senyawa kimia dan efek tanaman Kangkung air terhadap Uji sedative-Hipnotik. Sebanyak 30 mencit dalam 5 kelompok uji yaitu Kelompok control negatif, control positif dengan pemberian diazepam 10 mg/KgBB secara oral, Kelompok perlakuan dengan ekstrak Kangkung Air dosis 1 mg/KgBB, 2 mg/KgBB, dan $ mg/KgBB dengan metode rotaryroad dan Fireplace Test. Data yang didapat dianalisis dengan Shapiro-Wilk, kemudian dilanjutkan uji one way ANOVA dan Post Hoc Tests. Hasil menunjukkan adanaya efek sedasi ekstrak etanol kangkung air pada dosis 4 mg/20 BB. Kata kunci: SedatiF-Hipnotik, kangkung air, rotarod. ABSTRACT Treatment Sedatives-hypnotics using the class of depressants of Central Nervous System (CNS) are relatively not selective. However, drugs of this class if used prolonged can be toxic and cause death. Ipomoea aquatica has a good antioxidant effect. The aim of the test are to the show contains chemical coumpound and the effect of sedative-hypnotic test. Twenty five male mice divided into 5 group (N=5) which is called as negative control group, positive control group will be given Diazepam at dose 10mg/KgBW p.o and 3 treatment groups will be given Ipomea Aquatica Ectract (EKA) ad dose 1 mg/KgBW(I); 2 mg/kgBW(II); and 4mg/KgBW(III) p.o, In this study used rotarod and Fireplace method. Data were analyzed using Saphiro Wilk Test then One ways ANOVA and post hoc test. There is a sedation effect of Ipomea aquatica Extract at 4 mg/20 BB dose. Keywords: Sedative-Hypnotive Test, Ipomoea Aquatica, rotarod
AKTIVITAS KEMAMPUAN MEMORI SPASIAL FRAKSI ETIL ASETAT HERBA MENIRAN MERAH (PHYLLANTHUS URINARIA L.) DENGAN METODE RADIAL ARM MAZE Karunita Ika Astuti
BORNEO JOURNAL OF PHARMASCIENTECH Vol 3 No 2 (2019): Borneo Journal of Pharmascientech
Publisher : Sekolah Tinggi Ilmu Kesehatan Borneo Lestari Banjarbaru

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Abstract

ABSTRACTIntelligence is an ability to adjust with the environment by blends of attention, concentrationand short term memory. Phyllanthus urinary L. is a plant that have active content offlavonoid compound especially quersetin which efficacious in spatial memory activity. Thepurpose of this study was to determine, effective dose and histopathology of gyrus dentatus inanimal test after given ethyl acetate fraction of meniran herb. The research was conducted by administration of ethyl acetate fraction with doses 50 mg/kgBW, 100 mg/kgBW and 150mg/kgBW for 10 days to white male mice. The research to view error in memory by radialarm maze (RAM). Positive control using quercetin 42 mg/kg BW and negative control usingNa-CMC 0.5%. The most effective result at dose 100 mg/kgBW with shows value of 38.619%± 2.56, the best and smaller value if compared with 50 mg/kgBW and 100 mg/KgBW andnegative control, 49.195%±4.27; 53.130%±1.70; and 63.419%±4.55, respectively withpositive control value of 32.424%±9.13.Keywords: Radial arm maze, ethyl acetate fraction, red meniran (Phyllanthus urinary L.)
UJI AKTIVITAS ANTIDIARE EKSTRAK ETANOL 96% HERBA PUTRI MALU (Mimosa pudica L.) TERHADAP MENCIT JANTAN YANG DIINDUKSI Oleum ricini Karunita Ika Astuti; Fitriyanti; Nur Huda
BORNEO JOURNAL OF PHARMASCIENTECH Vol 4 No 1 (2020): Borneo Journal of Pharmascientech
Publisher : Sekolah Tinggi Ilmu Kesehatan Borneo Lestari Banjarbaru

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v4i1.276

Abstract

Mimosa pudica L. is one of plants which is used as antidiarrhea by the common people in the society. The objectives of this research is to determine the compounds and antidiarrhea activity of ethanolic 96% Mimosa pudica L extract by using masers method. The method is divided 5 groups and its has 5 mices, which negatif group is given by NaCMC 0,5%, positive group given by Loperamide HCL with doses 0,0052 mg/20g, and the ethanol extract with doses (100, 200, dan 400 mg/kgBB). After 30 minutes treatment to animal study, it is continued by Oleum ricini p.o. Observation is done during 4 hours by observed some parameter such as frequency of diarrhea and weight of feses. The result of compound Mimosa pudica L. extract such as alkaloid, flavonoid, tanin, saponin, and steroid. The data is analyzed by using Man Whitney showed Mimosa pudica L extract doses 400 mg/kgBB is efectives doses such as antidiarrhea which is able to decrease the frequency of diarrhea (P>0,585) and weight of feses (P>0,754).
Gambaran Penggunaan Obat Hipertensi pada Pasien Rawat Jalan di Puskesmas X Kabupaten Tanah Laut Kalimantan Selatan Karunita Ika Astuti; Uswatun Rahimah; Depy Oktapian Akbar
BORNEO JOURNAL OF PHARMASCIENTECH Vol 6 No 1 (2022): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v6i1.366

Abstract

Hypertension is one of the causes of early death when a concern all over the world which killed 8 million worldwide and almost 1.5 million people per year in the Southeast Asia region. The problem of hypertension will continue to develop if it is not handled properly it is estimated that 1.56 billion adults will be affected by hypertension in 2025. The purpose of this study is to find out the description of the use of hypertension drugs in one of Puskesmas in Tanah Laut from April to May 2019. This research was carried out observational with a cross sectional approach to 300 samples. Based on the gendre of the 300 prescriptions most women were 230 (77%) cases compared to men 70 (23%), the most prescribed drugs were in the age group 46-55 years had the largest number as hypertension sufferers with a percentage of 44 % or 132 patients, nifedipin (61%) 2,669 tablets and the number of patients 148 people (49%).
Uji Daya Hambat Ekstrak Etanol 96% Daun Jeruk Purut (Citrus Hystrix D.C. ) Terhadap Propionibacterium Acnes Fitriyanti Fitriyanti; Syaid Nofal Assegaf; Karunita Ika Astuti
BORNEO JOURNAL OF PHARMASCIENTECH Vol 6 No 2 (2022): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v6i2.471

Abstract

Acne is a disease on the surface of the skin that often causes pain and leaves red, pus-filled spots. The plant that can be developed as an antibacterial is the citrus tribe which is also useful as a flavor enhancer in cooking, namely kaffir lime leaves (Citrus hystrix D.C). The purpose of this study was to test the activity of 96% ethanol extract of kaffir lime leaves against the inhibition of the acne-causing bacteria Propionibacterium acnes. In testing the antibacterial activity of this study using a good method. Based on the results of phytochemical screening, the extract was positive for flavonoids, saponins, tannins, and steroids. Based on the test results of measuring the diameter of the inhibition zone of kaffir lime leaf extract at a concentration of 100%; 80%; 60%; 40%; 20%; and 10% by 22.133 mm; 19,333 mm; 17,266 mm; 15,933 mm, 14.9 mm; and 12.133 mm. Data were analyzed using SPSS with Mann Whitney to obtain a significant value for each concentration variation, with a value of sig <0.05, which means that there are significant differences in each treatment group.
Hubungan Tepat Pasien Terhadap Tepat Dosis Antibiotik ISPA pada Balita di Puskesmas Banjarbaru Utara Periode Tahun 2022 Baiq Nurdiana Ulfa; Karunita Ika Astuti; Helmina Wati
BORNEO JOURNAL OF PHARMASCIENTECH Vol 7 No 2 (2023): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v7i2.487

Abstract

Acute Respiratory Infection (ARI) is a pathological condition characterized by the invasion of microorganisms, namely bacteria and viruses, into the respiratory tract of human individuals. The misuse of antibiotics can result in the development of antibiotic resistance. The objective of this study is to assess the appropriate patient selection and dosage determination as well as investigate the correlation between patient selection and dosage of ARI antibiotics in toddlers attending the North Banjarbaru Health Center. The present study is a retrospective, non‐experimental investigation that examined patient medical records from January to April 2023. The sample consisted of 184 individuals who satisfied the predetermined inclusion and exclusion criteria. According to the findings of the research, the utilization of ARI antibiotics was characterized by the prevalence of Cotrimoxazol 85 (46.19%), followed by Amoxicillin 67 (36.41%), and Cefadroxil 32 (17.40%). The patients were evaluated accurately in 184 cases, representing 100% of the total. The correct dosage was administered in 155 instances, accounting for 84.2% of the total, while an incorrect dosage was administered in 29 cases, representing 15.8% of the total. The statistical analysis using the Mann‐Whitney test indicated that there was no significant relationship between the appropriate patient selection and the correct dosage administration, as evidenced by a p‐value greater than 0.05 (p = 1.000). The study findings indicated a lack of correlation between the appropriate patient selection and the correct dosage of ARI antibiotics administered to toddlers at the North Banjarbaru Health Center.