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All Journal Bioeksperimen: Jurnal Penelitian Biologi Jurnal Skala Kesehatan Jambura Journal of Chemistry JPP Jurnal Kesehatan Poltekkes Palembang Bantenese Jurnal Pengabdian Masyarakat SANITAS: Jurnal Teknologi dan Seni Kesehatan Lumbung Farmasi : Jurnal Ilmu Kefarmasian Journal of Medical Laboratory Research Jurnal Menara Pengabmas
Rachmawati, Nurmeily
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences

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Pengaruh Polaritas Pelarut terhadap Efisiensi Ekstraksi Total Alkaloid dari Daun Rambai (Sonneratia caseolaris) Masodah, Siti; hariati, Niken widiastuti; Rachmawati, Nurmeily; Nurhayati, Serli Dwi
Jurnal Skala Kesehatan Vol 17 No 1 (2026): Jurnal Skala Kesehatan Edisi Januari 2026
Publisher : Politeknik Kementerian Kesehatan Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/jsk.v17i1.494

Abstract

Diabetes mellitus is a non-communicable disease with a rising prevalence. Alkaloids are known to have antidiabetic effects by inhibiting carbohydrate-digesting enzymes and enhancing glucose metabolism. This study aimed to determine the total alkaloid content of Rambai leaves (Sonneratia caseolaris) using solvents with different polarities: ethanol and n-hexane. A descriptive study was conducted using the maceration method, followed by quantification of alkaloids with the quinine equivalent method using a UV-Vis spectrophotometer. Results showed that ethanol extract produced a higher yield (17.72 g; 35.44%) compared to n-hexane (3.09 g; 6.18%). The alkaloid content in the ethanol extract was 414.43 µg/g, nearly twice that of n-hexane (217.09 µg/g). Statistical analysis revealed a significant difference (p<0.001). Ethanol was proven to be more effective in extracting polar to semi-polar alkaloid compounds. The high alkaloid content indicates Rambai leaves have potential as a natural source for diabetes therapy. These findings provide a foundation for future product development and preclinical trials.
Potensi Antibakteri Kombinasi Ekstrak Daun Mangga (Mangifera indica L.) dan Daun Kirinyuh (Chromolaena odorata L.) Terhadap Staphylococcus aureus Anliza, Syarah; Marwin, Deisya Tyas; Rachmawati, Nurmeily; Hamtini
Journal of Medical Laboratory Research Vol. 4 No. 1 (2025): Journal of Medical Laboratory Research
Publisher : Politeknik Kesehatan Kementerian Kesehatan Banten

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Abstract

Infectious diseases caused by Staphylococcus aureus are one of the health problems occurring in Indonesia. Infectious diseases can be treated with antibiotics. However, antibiotics used without proper prescription can trigger antibiotic resistance. To overcome antibiotic resistance, a combination of natural ingredients such as kirinyuh leaves (Chromolaena odorata L.) and mango leaves (Mangifera indica L.) can be used. This study aims to determine the inhibitory activity and effective concentration of the combination of mango leaves extract (Mangifera indica L.) and kirinyuh leaves  extract (Chromolaena odorata L.) as antibacterial agents against Staphylococcus aureus. The methods used in this study included maceration to prepare mango leaves and kirinyuh leaves extract, phytochemical screening to identify the presence of secondary metabolites in the kirinyuh leaves and mango leaves extract, and the disk diffusion method for antibacterial testing. The results showed inhibitory activity at all concentrations due to the presence of secondary metabolites in the kirinyuh leaves and mango leaves extracts. At a 1:3 concentration, an inhibition zone of 18 mm was obtained; at a 1:1 concentration, an inhibition zone of 19 mm was obtained; at a 3:1 concentration, an inhibition zone of 20 mm was obtained. The effective concentration of the combination as an antibacterial agent is the 3:1 concentration. The results of this study fall into the strong category, indicating that the combination of mango leaves and kirinyuh leaves extracts has antibacterial efficacy against Staphylococcus aureus.
Community Empowerment in Increasing Awareness about The Danger of Cholesterol in The Body Rachmawati, Nurmeily; Anliza, Syarah
Jurnal Menara Pengabmas Vol. 1 No. 1 (2023): Jurnal Menara Pengabmas
Publisher : POLTEKKES KEMENKES BANTEN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36743/jmp.v1i1.514

Abstract

Kesehatan merupakan salah satu unsur penting dalam kehidupan manusia. Salah satu permasalahan terkait kesehatan adalah kesadaran dari setiap individu untuk menciptakan lingkungan dengan pola hidup sehat. Kegiatan yang dapat dilakukan untuk meningkatkan kesadaran masyarakat akan kesehatan berupa peningkatan pengetahuan, pencegahan penyakit, dan pemulihan kesehatan. Berdasarkan hasil Riset Kesehatan Dasar (Riskesdas) pada tahun 2018 menunjukkan peningkatan prevelansi penyakit stroke pada usia diatas 15 tahun dan cenderung tinggi pada rentang usia 55-64 tahun. Beberapa penyebab Penyakit Tidak Menular (PTM) tersebut adalah perilaku gaya hidup, kurang aktivitas fisik, dan minimnya pengetahuan masyarakat tentang kesehatan. Rumusan masalah pada kegiatan pengabdian masyarakat ini yaitu perlunya dilakukan pemberdayaan masyarakat melalui suatu kegiatan yang informative dalam rangka meningkatkan pengetahuan dan kesadaran masyarakat akan bahaya kolesterol didalam tubuh. Tujuan kegiatan ini yaitu dengan meningkatnya pengetahuan masyarakat akan bahaya kolesterol terhadap kesehatan tubuh dapat menjadikan kesadaran masyarakat akan pola hidup sehat menjadi lebih baik. Kegiatan pengabdian masyarakat ini mengukur pengetahuan awal sebelum dan sesudah masyarakat tentang bahaya kolesterol didalam tubuh serta pengukuran kadar kolesterol didalam darah menggunakan metode POCT. Hasil menunjukkan adanya peningkatan pengetahuan rata-rata masyarakat sebesar 37,17% dan terdapat 7 orang warga (21%) yang memiliki kadar kolesterol diatas 200 mg/dL.
Co-Authors ahmad yani Aminah Aminah Anliza, Syarah Annisa, Istiana Audina, Gina Bangun Wijonarko, Bangun Fadillah, M.Arief Fadillah, Muhammad Arief Hamtini - Hamtini Hariati, Niken Widiastuti Marwin, Deisya Tyas masodah, siti Meilina, Meilina Nurhayati, Serli Dwi Rinawati, Diana Trisna, Citra Yuniar, Isna Zulkifli, M. Zidan