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Journal : Science and Community Pharmacy Journal

PHYTOCHEMICAL SCREENING OF ETHANOL EXTRACT OF TREMBESI FRUIT SEEDS (Samanea saman) Saptawati, Tunik; Dayanti, Ema; Rachma, Firstca Aulia; Ovikariani
Science and Community Pharmacy Journal Vol. 1 No. 2 (2022): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v1i2.325

Abstract

Trembesi (Samanea saman) is a fast-growing plant from Central America and Northern South America. the Trembesi Tree is an easily recognize tree because it has an umbrella-shaped canopy with a canopy diameter greater than its height, the trembesi fruit is blackish-brown when ripe, with seeds embedded in the flesh of the fruit. This study aims to determine the class of compounds contained in the ethanol extract of trembesi fruit seeds extraction by maceration method using 70% ethanol solvent. The analysis uses univariates that present data with calculation results. The extract results were obtained by weight of 91% with an amendment value of 18.20%. The phytochemical screening were carried out with color tests and emphasized by the TLC test. The trembesi fruit seed ethanol extract containing alkaloid, flavonoids, saponins, and tannins compounds.
The Effect of the Addition of Virgin Coconut Oil (Vco) on the Physical Stability of Carrot Sunscreen Preparations (Daucus carota L.) Kalsum, Ummi; Nihlatunnaja, Nadiya; Firstca Aulia Rachma
Science and Community Pharmacy Journal Vol. 2 No. 1 (2023): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v2i1.354

Abstract

UV rays have harmful side effects of free radicals, dry skin can reduce the body's defenses against the effects of free radicals, antioxidants have activity as a free antiradical, Carrots have antioxidant activity due to the presence of carotenoid compounds, Fatty acid content from VCO which has the function of softening and moisturizing the skin.This study aims to determine the effect of the addition of Virgin Coconut Oil (VCO) on physical stability in the formulation of carrot sunscreen cream preparations. As well as Knowing the effectiveness of antioxidants on carrot tubers. Research methods test the physical characteristics of the preparation (organoleptic, pH, homogeneity, adhesion and dispersion), Cycling test cream stability test and in the onewayanova test.The results of the study obtained the influence of the stability of oily texture and rancid odor in formula III (21%) and based on data analysis, the higher the concentration, the wider the distribution power of the preparation and the decrease in the adhesion of the preparation. Conclusion The addition of Virgin Coconut Oil (VCO) affects the stability of texture and smell in formula III (21%) and based on data analysis the addition of Virgin Coconut Oil (VCO) to carrot sunscreen cream (Daucus carota L.) the higher the concentration the wider the dispersal power of the preparation and the decrease in adhesion of the preparation.
AN ANALYSIS OF FLAVONOID COMPOUNDS FROM ETHANOL EXTRACT OF MORINGA LEAVES (MORINGA OLEIFERA L.) USING FTIR AND HPLC Puruhita, Ranatri; Sulistyoningsih, Danik; Kristiyanti, Winnie; Aulia Rachma, Firstca
Science and Community Pharmacy Journal Vol. 3 No. 2 (2024): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v3i2.583

Abstract

Moringa leaves contain flavonoids, phenols, tannins, alkaloids, saponins, terpenoids, and steroids. The flavonoid and phenol content has antioxidant activity. This research aimed to determine compounds in the ethanol extract of Moringa leaves To determine the type of flavonoid content using FTIR and HPLC. FTIR analysis shows that Moringa leaves possibly contain compounds from quercetin derivatives, which is supported by HPLC analysis. This quercetin compound is a group of flavonols that are characterized by the presence of a hydroxyl group and a carbonyl group. HPLC analysis was carried out by making a quercetin standard with a concentration of 200 ppm. The resulting wavelength is 254 nm. The results of the quercetin standard chromatogram which contains one main peak obtained from the quercetin standard. This peak shows the retention time at 3 minutes. The results of the standard chromatogram, quercetin has an outer area of ​​44763473 and a sample area of ​​17455781 with 2 times dilution, so the % purity of fraction 9 for quercetin is 77.99 ppm. This HPLC analysis shows that Moringa leaves probably contain quercetin derivatives which are characterized by the same retention time between the sample and the quercetin standard, namely at a retention time of 3 minutes, and have a peak pattern that is almost the same as the quercetin standard.