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Journal : Medicra (Journal of Medical Laboratory Science/Technology)

Potential of Seed Powder (Tamarindus indica L.) on Cholesterol Levels: Potensi Seduhan Serbuk Biji Asam Jawa (Tamarindus indica) Terhadap Kadar Kolesterol Purwaningsih, Nur Vita; Widyastuti, Rahma; Maulidiyanti, Ellies Tunjung Sari; Saputro, Tri Ade; Rohmayani, Vella; Ainutajriani, Ainutajriani
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 6 No. 1 (2023): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v6i1.1713

Abstract

ABSTRACT Coronary heart disease (CHD) is the leading cause of death after stroke in all age groups at 12.9%. The main reason is the amount of cholesterol in the blood. Tamarind (Tamarindus indica) is a traditional herb that has the potential to lower cholesterol, because it contains flavonoids, saponins, foliphenols, pectin, organic acids, vitamin B and vitamin C that can lower cholesterol. The purpose of this study was to determine the effect of tamarind seed powder (Tamarindus indica) on cholesterol levels. This type of research is experimental with pre-test and post-test with control group research design. The population and sample of this study were a group of mice totaling 32 mice. The location of this research was conducted at the Animal Husbandry Center (PUSVETMA). Data collection procedures were carried out by examining the cholesterol levels of mice before and after treatment. The data obtained were followed up with normality test and independent t test. The results of the study using the unpaired t test gave the result of p=0.000 (p<0.05). The conclusion of this study is that there is an effect of seed powder (Tamarindus indica) on cholesterol levels. Keyword : Seeds Tamarindus indica L., cholesterol levels, Mice (Mus musculus)
Cellular Immune Responses and Hepatitis B Surface Antigen (HBsAg) in Alcohol-Consuming Fishermen : Respon Imun Seluler dan HBsAg pada Nelayan Pengonsumsi Alkohol Purwaningsih, Nur Vita; Saputro, Tri Ade; Azizah, Fitrotin; Maulidiyanti, Ellies Tunjung Sari; Budiman, Waras; Anggraini, Lukita
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 8 No. 2 (2025): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v8i2.1803

Abstract

Hepatitis B infection remains a global health problem with long-term complications such as cirrhosis and hepatocellular carcinoma. Alcohol consumption is known to impair immune function and exacerbate hepatitis B virus (HBV) infection. Fishermen represent a high-risk occupational group due to alcohol consumption habits and limited healthcare access. This study aimed to analyze the relationship between alcohol consumption levels and hepatitis B infection status through HBsAg testing and lymphocyte count among fishermen. This was a descriptive observational study with a cross-sectional approach involving 40 fishermen in Gresik Regency. Data were collected through alcohol consumption questionnaires and laboratory tests, including HBsAg examination using a Rapid Test and lymphocyte count using a hematology analyzer. Data were analyzed using Chi-square and ANOVA tests with a significance level of p < 0.05. A total of 30% of respondents were HBsAg reactive, with the highest proportion found in the heavy alcohol consumption group (50%). The mean lymphocyte count decreased with increasing alcohol intake: 2.580 ± 420 cells/µL in the light group, 2.120 ± 390 cells/µL in the moderate group, and 1.780 ± 360 cells/µL in the heavy group (p = 0.012). There was a significant relationship between alcohol consumption level, HBsAg status, and lymphocyte count among fishermen. High alcohol consumption may reduce cellular immunity and increase the risk of persistent hepatitis B infection. HBsAg testing and lymphocyte count can serve as early indicators for health screening in high-risk occupational groups such as fishermen.