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All Journal Jurnal Kedokteran Jurnal Biologi Tropis Sasambo Journal of Pharmacy
Solehah, Kurnia
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology

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Uji Aktivitas Antiparamphitomiasis Infus Bunga Widuri (Colotropis gigantea) Terhadap Paramphistomum spp. Secara In Vitro Solehah, Kurnia; Damiyati, Siska Yunita; Pratama, Iman Surya; Tresnani, Galuh
Jurnal Kedokteran Vol 9 No 4 (2020): Jurnal Kedokteran volume 9 no 4 2020
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v9i4.454

Abstract

Latar Belakang: Prevalensi paramphistomiasis di provinsi Nusa Tenggara Barat tahun 2014 mencapai 20,7%. Tujuan penelitian untuk membandingkan aktivitas infus bunga Widuri berbagai konsentrasi terhadap Paramphistomum spp. secara in vitro terhadap Albendazol 10% b/v. Metode: Paramphistomum dewasa dikelompokkan ke dalam 5 kelompok : kontrol negatif (larutan NaCl 0,9% b/v), kontrol positif (Albendazol 10% b/v), dan infus bunga Widuri (5, 20 dan 40% b/v). Tiap kelompok diinkubasi pada suhu 37oC, kemudian diamati waktu kematian setiap 15 menit selama 5 jam. Persentase mortalitas ditentukan dan dianalisis secara statistik dengan parametrik dan non-parametrik menggunakan perangkat lunak SPSS v.16; Hasil: Rerata waktu kematian untuk tiap kelompok berturut-turut 270; 23,33 ± 5.77; 16,67 ± 11.55; 103,33 ± 5.77; dan 146,67 ± 5.77 menit. Kesimpulan: Infus bunga Widuri 5% b/v efektif sebagai antiparamphistomiasis ditinjau dari rerata waktu mortalitas yang berbeda bermakna (p<0,05) lebih rendah dibandingkan Albendazol 10% b/v.
Skrining fitokimia ekstrak air dan ekstrak etanol 70% Propolis Trigona sp. asal Lombok Utara Ananta, Muhammad Naufal Farras; Nuralyza, Imasayu; Solehah, Kurnia; Pratama, Iman Surya; Aini, Siti Rahmatul
Sasambo Journal of Pharmacy Vol. 5 No. 1 (2024): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v5i1.305

Abstract

Propolis Trigona sp. has many benefits closely related to the secondary metabolites contained therein. Previous research related to propolis screening of Trigona sp. from North Lombok has been carried out. Still, it has yet to be carried out in the maceration method (1:20 w/v) with 70% water and ethanol solvent to obtain a comparison of secondary metabolites between the two solvents. This study aims to identify the content of secondary metabolites in the water extract and 70% ethanol extract of propolis Trigona sp. from North Lombok. Propolis was macerated with water and 70% ethanol solvent. The viscous extract was identified for its physical characteristics, consistency, color, and chemical characteristics through phytochemical screening. The results of the phytochemical screening showed that the aqueous extract and 70% ethanol extract contained alkaloids, flavonoids, tannins, triterpenoids, and quinones. Both extracts showed negative saponin results.
Phytocemical Screening Water Extract of Pineapple Skin (Ananas comosus (L.) Merr) from East Lombok Angelina, Varelia; Solehah, Kurnia; Hasina, Raisya
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.7853

Abstract

Pineapple (Ananas comosus (L.) Merr) is empirically used as a medicine to cure constipation, nausea, urinary tract disorders, flu, and various skin diseases. Secondary metabolites that cause this activity are alkaloids, tannins, flavonoids, saponins and triterpenoids. Secondary metabolite phytochemical screening has been carried out on pineapple peel juice and freeze-dried pineapple peel powder, but no tests have been carried out on dehydrated pineapple peel powder. The primary objective of this study was to determine of secondary metabolites in pineapple peel water extract. The powdered pineapple peel extract was made using pineapple peel juice that had been dried in a dehydrator at 40ºC for two 24-hour cycles. Phytochemical screening makes use of a tube test, which involves qualitative observation using separate reagents for each chemical. Alkaloids, flavonoids, quinones, tannins, and triterpenoids were found in pineapple skin as secondary metabolites, but saponin chemicals were found to be absent.
Co-Authors Aini, Siti Rahmatul Ananta, Muhammad Naufal Farras Angelina, Varelia Damiyati, Siska Yunita Galuh Tresnani Hasina, Raisya Nuralyza, Imasayu Pratama, Iman Surya Pratama, Iman Surya