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All Journal Jurnal Biologi Tropis Sasambo Journal of Pharmacy SALUT: Journal of Social and Education
Nuralyza, Imasayu
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Social Sciences Other

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Skrining fitokimia ekstrak air dan ekstrak etanol 70% Propolis Trigona sp. asal Lombok Utara Ananta, Muhammad Naufal Farras; Nuralyza, Imasayu; Solehah, Kurnia; Pratama, Iman Surya; Aini, Siti Rahmatul
Sasambo Journal of Pharmacy Vol. 5 No. 1 (2024): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v5i1.305

Abstract

Propolis Trigona sp. has many benefits closely related to the secondary metabolites contained therein. Previous research related to propolis screening of Trigona sp. from North Lombok has been carried out. Still, it has yet to be carried out in the maceration method (1:20 w/v) with 70% water and ethanol solvent to obtain a comparison of secondary metabolites between the two solvents. This study aims to identify the content of secondary metabolites in the water extract and 70% ethanol extract of propolis Trigona sp. from North Lombok. Propolis was macerated with water and 70% ethanol solvent. The viscous extract was identified for its physical characteristics, consistency, color, and chemical characteristics through phytochemical screening. The results of the phytochemical screening showed that the aqueous extract and 70% ethanol extract contained alkaloids, flavonoids, tannins, triterpenoids, and quinones. Both extracts showed negative saponin results.
Potential of Ipomoea pes-caprae Extract as an Antibacterial: A Literature Review Nuralyza, Imasayu; Hanifa, Nisa Isneni
Jurnal Biologi Tropis Vol. 25 No. 2 (2025): April-Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i2.8839

Abstract

The increasing prevalence of antibiotic resistance shows the urgent need for discovering alternative compounds with potential antibacterial activity. Ipomoea pes-caprae (commonly known as katang-katang) has emerged as a promising natural source of antibacterial agents due to its bioactive constituents, including phenolics, alkaloids, flavonoids, and saponins. The purpose of this article is to review and compare previously reported antibacterial research findings of Ipomoea pes-caprae against various bacterial species. The literature review was conducted using relevant sources obtained from Google Scholar and PubMed databases, covering publications from 2014 to 2024. The findings show that different parts of Ipomoea pes-caprae exhibit antibacterial activity against both Gram-positive and Gram-negative bacterial strains, attributed to the presence of antibacterial compounds. Factors influencing the antibacterial activity of the extracts include the type of test bacteria, the extract concentration, and the solvent used. It can be concluded that Ipomoea pes-caprae has potential as an antibacterial agent.
Literature Review : Development of Monoclonal Antibodies Using The Expression System of Nicotiana benthamiana Anugraheni, Audina Filsa Nur; Nuralyza, Imasayu; Maulira, Dinda Ayu; Ramadhani, Aliza Salsabila; Nugrahani, Baiq Dwiyan; Sunarwidhi, Anggit Listyacahyani
Jurnal Biologi Tropis Vol. 25 No. 2 (2025): April-Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i2.8919

Abstract

Monoclonal antibodies (mAbs) have become a key component in modern biotechnology and healthcare, playing essential roles in the treatment of diseases such as cancer, viral and bacterial infections, asthma, and in diagnostic applications. However, conventional mAb production using mammalian cell systems is costly, time-consuming, and presents scalability limitations. To address these challenges, current technological advances have led to the development of alternative platforms using plant-based expression systems. This review aims to explore the potential and progress in producing monoclonal antibodies through the Nicotiana benthamiana plant-based expression system, which offers several advantages including rapid production, cost efficiency, greater production capacity, and reduced risk of contamination. The method employed in this review is a literature study conducted through database searches (Google Scholar, PubMed, Science Direct, and others) focusing on peer-reviewed articles from 2015 to 2024. The articles were selected and then analyzed thematically was performed to extract relevant data. The results indicate that Nicotiana benthamiana can efficiently produce functional mAbs with glycosylation profiles comparable to mammalian systems. In addition, plant antibodies have also been successfully applied in various therapeutic and diagnostic studies. Further research is needed to ensure the safety and effectiveness of Nicotiana benthamiana plant-based mAb, as well as efforts to develop production scale for wider medical applications.
Nucleoside Antiviral Therapy for Herpes Zoster: A Literature Review Ain, Nisrina Huurul; Rahmatullah, Lalu Mas’ud; Utari, Widi Gustita; Nuralyza, Imasayu; Salsabiella, Baiq Rani; Maghfirahandini, Reivirly Khairadaty; Aini, Siti Rahmatul; Nurhidayati, Nurhidayati
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.10006

Abstract

Herpes zoster is a viral skin infection caused by the reactivation of the varicella-zoster virus, which remains latent in the dorsal root ganglia of the spinal cord and the cranial sensory ganglia. One of the most widely used classes of antiviral agents in the treatment of herpes zoster is nucleoside analogs. This study aims to review the use of nucleoside analogs in the management of herpes zoster. The method employed was a literature review of relevant research articles. The findings indicate that nucleoside analogs commonly used in herpes zoster therapy include acyclovir, valacyclovir, famciclovir, and brivudine. These agents are administered in various doses, routes, and therapeutic purposes, such as alleviating acute symptoms, accelerating skin lesion healing, preventing postherpetic neuralgia, and serving as prophylactic therapy in special conditions such as cancer or organ transplantation. Overall, the use of nucleoside analogs has proven effective in inhibiting varicella-zoster virus replication, reducing symptom intensity, and minimizing the risk of complications.
Urgensi Pendidikan Pancasila Untuk Mencegah Radikalisme Arzy, Muhammad Dimas; Marasabessy, Keysha Nabilla Putri; Salsabila, Ghina; Attaya, Kalisa; Nuralyza, Imasayu; Nugrahani, Baiq Dwiyan; Dalila, Virga Fathiya
Journal of Social and Education Vol. 2 No. 1 (2025): Journal of Social and Education
Publisher : Lembaga Riset dan Publikasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66909/lrp.salut.v2i1.131

Abstract

Radikalisme merupakan tantangan besar bagi persatuan Indonesia karena tidak sejalan dengan prinsip-prinsip Pancasila. Pendidikan Pancasila dianggap sebagai elemen kunci dalam menangkal paham radikal, khususnya di kalangan pemuda. Studi ini bertujuan untuk menganalisis pentingnya memperkuat pendidikan Pancasila sebagai upaya pencegahan radikalisme di dunia pendidikan dan masyarakat. Beberapa manfaat penelitian ini antara lain: meningkatkan kesadaran akan perlunya penguatan ideologi nasional, menjadi pedoman dalam menyusun kurikulum pendidikan berbasis karakter, serta mempromosikan kolaborasi antar-pemangku kepentingan untuk melawan radikalisme. Metode penelitian yang digunakan adalah studi literatur dengan menganalisis sumber-sumber akademis terpercaya dari jurnal ilmiah dalam kurun waktu sepuluh tahun terakhir. Temuan penelitian mengungkap bahwa strategi efektif untuk memperkuat ketahanan ideologi pemuda dan mencegah radikalisme meliputi: penanaman nilai Pancasila sejak dini, optimalisasi media digital, penyatuan nilai-nilai Pancasila dalam kurikulum, serta pendekatan multikultural dan kerja sama lintas sektor.
Co-Authors Ain, Nisrina Huurul Aini, Siti Rahmatul Ananta, Muhammad Naufal Farras Anugraheni, Audina Filsa Nur Arzy, Muhammad Dimas Attaya, Kalisa Dalila, Virga Fathiya Maghfirahandini, Reivirly Khairadaty Marasabessy, Keysha Nabilla Putri Maulira, Dinda Ayu Nisa Isneni Hanifa Nugrahani, Baiq Dwiyan Nurhidayati Nurhidayati Pratama, Iman Surya Rahmatullah, Lalu Mas’ud Ramadhani, Aliza Salsabila Salsabiella, Baiq Rani Salsabila, Ghina Solehah, Kurnia Sunarwidhi, Anggit Listyacahyani Utari, Widi Gustita