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All Journal Jurnal Ilmu Kedokteran (Journal of Medical Science) Oto Rhino Laryngologica Indonesiana Majalah Kedokteran Andalas Health and Medical Journal Andalas obstetrics and gynecology journal Science Midwifery Scientific Journal
Mayorita, Pamelia
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Ovarian Yolk Sac Tumor pada Usia Tua ; A Rare Case Kusumardani, Dini; Mayorita, Pamelia; Novianti, Hera
Health and Medical Journal Vol 5, No 2 (2023): HEME May 2023
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v5i2.1267

Abstract

Pendahuluan: Yolk sac tumor  merupakan subtipe paling umum kedua atau sekitar 15-20% dari semua germ cell tumor yang biasanya ditemukan pada wanita usia muda.1Yolk sac tumor  ini jarang terjadi pada wanita usia tua atau postmenopause, dapat berupa komponen yolk sac murni atau campuran dengan komponen tumor epitel lainnya. Laporan Kasus: Kami melaporkan seorang wanita usia 54 tahun dengan keluhan perut membesar seperti full- term pregnancy. Hasil pemeriksaan USG adalah tumor ovarium. Hasil pemeriksaan laboratorium menunjukkan dalam batas normal. Pasien menjalani prosedur optimal debulking. Pemeriksaan histopatologi adalah Ovarian Yolk Sac Tumor. Kesimpulan: Meskipun kasus ini jarang terjadi, Ovarian Yolk Sac Tumor dapat ditemukan pada usia tua atau postmenopause yang umumnya murni atau campuran dengan tumor epitel lainnya, pada kasus  ini ditemukan Yolk Sac Tumor ovarium murni. Diagnosis ditegakkan berdasarkan anamnesis, pemeriksaan fisik, pemeriksaan radiologis dan pemeriksaan histopatologis. Pemeriksaan histopatologis merupakan gold standard untuk diagnosis Ovarian Yolk Sac Tumor. Diagnosis bandingnya adalah Immature Teratoma, Sclerosing Stromal Tumor dan Dermoid Cyst. Kecurigaan klinis yang tinggi, diagnosis dan penatalaksanaan yang cepat dapat memberikan prognosis yang baik.
Difficulty in Diagnosing Peritoneal Fluid Cytology in Ovarian Yolk Sac Tumor Cases Pemuda, Haris; Yenita, Yenita; Mayorita, Pamelia; Setiawati, Yessy; Muhammad, Syamel
Andalas Obstetrics And Gynecology Journal Vol. 5 No. 2 (2021)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.2.278-286.2021

Abstract

Objective : This article objective is to describe cytology diagnosis difficulties of yolk sac tumors of the ovary.Method : Case reports and literature review.Case : The author reports the case of a 24 year old woman who complained of an enlarged stomach. Serum AFP increased to 16,519.7 U/mL. Ultrasound examination revealed solid and irregular mass of ovarian, so the conclusion was suspect ovarian carcinoma. Conclusion of CT scan examination was a solid ovarian tumor. The working diagnosis was suspect ovarian carcinoma. Optimal debulking was performed, accompanied by taking a sample from the peritoneal rinse fluid. Microscopic examination of peritoneal fluid showed the distribution and group of cells with pleomorphic nuclei, partly hyperchromatic, partly vesicular with coarse chromatin and prominent nucleoli. There were also cells with polygonal nuclei, small nuclei, basophilic and vacuole cytoplasm with a mucoid background. These cells formed a solid arrangement. Conclusion from these features was carcinoma metastases to the peritoneal fluid. Microscopic examination from tumor tissue sample showed an ovarian yolk sac tumor appearance.Conclusion : Cytologic examination of peritoneal fluid in cases of ovarian yolk sac tumor is quite difficult to determine the diagnosis. This is due to the microscopic appearance of tumor cells which often looks like a carcinoma and limited literature about this tumors in the peritoneal fluid.Keywords: Yolk sac tumor, ovary, 
Ko-Insiden Rhinosinusitis Kronis dengan Polip Hidung dan Neurofibroma Irfandy, Dolly; Budiman, Bestari Jaka; Ikhlas, Khairani Ayunanda; Mayorita, Pamelia
Oto Rhino Laryngologica Indonesiana Vol. 53 No. 2 (2023): VOLUME 53, NO. 2 JULY - DECEMBER 2023
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v53i2.611

Abstract

Background: Nasal polyps are painless inflammatory lesions originated from around the middlemeatus or paranasal sinus cavity; while neurofibroma is benign peripheral nerve sheath tumor. Purpose:To report a rare case of neurofibroma concurrently with nasal polyps in chronic rhinosinusitis. Casereport: A 64-year-old female with chief complaint congestion on the right nose cavity. There was a mass on both nasal cavities. Patient diagnosed with benign mass at right nasal cavity and chronic rhinosinusitis with nasal polyps at left nasal cavity; with a differential diagnosis of chronic rhinosinusitis with bilateral nasal polyps. Computer tomography scan results showed homogeneous isodense lesion in the right nasal cavity, and mucosal thickening in left nasal cavity and maxillary sinus. Patient was managed with total extirpation of the bilateral nasal cavity mass and functional endoscopic sinus surgery. Pathological examination revealed neurofibroma in the right nasal cavity and polyps in the left nasal cavity. Clinical question: “How to differentiate inflammation with tumor of nasal and paranasal sinuses? Is there a causal relationship?” Review method: Literature searching was performed with the keywords “nasal cavity neurofibroma”, AND “nasal polyps”, AND ”chronic rhinosinusitis” through database Google Scholar, PubMed, and hand searching/e-book. Result: There were 11 literatures published in the last 5 years, and 7 articles relevant with the subject. Conclusion: Chronic rhinosinusitis with nasal polyps, along with neurofibroma on nasal cavity is a rare co-incidence, and there was no correlation between those lesions. Pathological examination is a gold standard in differentiating a definite diagnosis of neurofibromas and polyps.Keywords: nasal cavity neurofibroma, nasal polyps, chronic rhinosinusitis
Co-Authors Aini, Julpa Nurul Aswiyanti Asri Bestari Jaka Budiman Devianti, Loli Dolly Irfandy Hafizhah, Ataya Handriyani, Fitri Nur Hardian, Sonny henny Mulyani Ikhlas, Khairani Ayunanda Kusumardani, Dini Muhammad, Almu Nelzima, Maisyah Novianti, Hera Noza Hilbertina, Noza O ktora, Meta Zulyati Octavia, Tri Aryati Oktora, Meta Zulyati Pemuda, Haris Rahmi Ramadhani Setiawati, Yessy Syamel Muhammad Tofrizal Yenita .