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All Journal As-syifaa Jurnal Farmasi JMM (Jurnal Masyarakat Mandiri) JPSCR : Journal of Pharmaceutical Science and Clinical Research Majalah Farmasetika Jurnal Promotif Preventif AS-SYIFA : Jurnal Pengabdian dan Pemberdayaan Kesehatan Masyarakat Sejahtera: Jurnal Inspirasi Mengabdi Untuk Negeri Indonesian Research Journal on Education Indonesian Health Journal Indonesian Journal of Community Empowerment Jurnal Sains dan Kesehatan
Musdar, Tamzil Azizi
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Journal : Jurnal Sains dan Kesehatan

 1 
Formulasi dan Uji Efektivitas Shampo Antiketombe Minyak Atsiri Seledri (Apium graveolens) terhadap Jamur Candida albicans: Formulation and Effectiveness Test of Anti-dandruff Shampoo Essential Oil of Celery (Apium graveolens) against Candida albicans Fungus Asti Vebriyanti Asjur Asjur; Syaifullah Saputro; Tamzil Azizi Musdar; Mifta Khaerati Ikhsan
Jurnal Sains dan Kesehatan Vol. 4 No. 5 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i5.1265

Abstract

Celery plants contain limonene which belongs to the terpen group which has the potential as antifungal. This study aims to determinethe formulation of celer essential oil anti-dandruff gel shampoo that meets the physical quality requirements with a concentration 0f 1%, 5%, 10%, and to test the effectiveness of celery essential oil anti- dandruff gel shampoo against the fungus Candida albicans that causes dandruff. The research method was carried out experimentally by making an anti-dandruff gel shampoo formula containing celery (Apium graveolens) essential oil and testing its effectiveness against the fungus Candida albicans that causes dandruff using the well method. This study tested the antifungal effectiveness of essential oil anti-dandruff gel shampoo from formula 0 without celery essential oil (blank) as a negative control, formula 1 with 1% celery essential oil concentration, formula 2 with 5% celery essential oil concentration, formula 3 with 10% celery essential oil concentration, and dandruff shampoo containing 2% ketoconazole as a positive control. The result showed that 1. Celery essential oil can be formulated into anti-dandruff gel shampoo preparations that meet the physical quality requirement. 2. The antifungal effect of celery essential oil anti-dandruff gel shampoo on Candida albicans fungus is very strong with an average inhibitor zone diameter of 20,36 mm in formula 1 21,40 mm in formula 2, 21,60 mm in formula 3. There were differences in the inhibitor vale of each concentration of celery essential oil gel shampoo (p<0,05). Concentration of 5% has provided an optimal effect in inhibiting the growth of the fungus Candida albicans.
Formulasi dan Uji Aktivitas Antioksidan Sediaan Face Mist Ekstrak Etanol Kulit Apel Hijau (Pyrus malus L.) dengan Metode DPPH: Formulation and Antioxidant Activity Face Mist Preparation Ethanol Extract Green Apple Peel (Pyrus malus L.) with DPPH Methods Asti Vebriyanti Asjur; Elvira Santi; Tamzil Azizi Musdar; Syaifullah Saputro; Rosmiati Anggraini Rahman
Jurnal Sains dan Kesehatan Vol. 5 No. 3 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i3.1750

Abstract

Green apple skin (Pyrus malus L.) is a fruit that is rich in nutritional content. especially antioxidant chemicals that are beneficial for the human body. This study aims to determine the ethanol extract of green apple peel (Pyrus malus L.) can be made in face mist preparations and to determine the ICso value of face mist preparations from green apple peel ethanol extract (Pyrus malus L.) can provide antioxidant activity This research used the method and made a face mist preparation using various extract concentrations in formula 1 0.1%, formula 2 0.3% and formula 3 0.5% and tested the antioxidant activity using the DPPH method. Green apple peel extract can be made into a face mist, based on the results of the cycling test, the three formulas for the face mist preparation, the ethanol extract of the green apple peel (Pyrus malus L.) has good physical stability of face mist, which is 18.83 ppm which has strong antioxidant activity, formula 2 (0.3%) which is 9.19 ppm has a very strong antioxidant value, and formula 3 (0.5%) which is 6.51 ppm has a very strong antioxidant value. green apple (Pyrus malus L.) can be formulated into a stable face mist preparation before and after the cycling test and the IC50 value of formula 3 (0.5%) is 6.51 ppm which has very strong antioxidant activity. Keywords: Green Apple Peel, Antioxidant, DPPH UV-vis Spectrofotometry Abstrak Kulit apel hijau (Pyrus malus L.) merupakan buah yang kaya akan kandungan gizi, terutama bahan kimia antioksidan yang bermanfaat bagi tubuh manusia. Penelitian ini bertujuan untuk mengetahui ekstrak etanol kulit apel hijau (Pyrus malus L.) dapat dibuat dalam sediaan face mist  dan mengetahui nilai IC50 sediaan face mist dari ekstrak etanol kulit apel hijau (Pyrus malus L.) dapat memberikan aktivitas antioksidan. Penelitian ini menggunakan metode dan membuat sediaan face mist menggunakan variasi konsentrasi ekstrak pada formula 1 0,1%, formula 2 0,3% dan formula 3 0,5% dan menguji aktivitas antioksidan menggunakan metode DPPH. Ekstrak kulit apel hijau dapat dibuat sediaan face mist, berdasarkan hasil uji cycling test ketiga formula sediaan face mist ekstrak etanol kulit apel hijau (Pyrus malus L.) memiliki stabilitas fisik face mist yang baik. Hasil IC50 yang diperoleh berturut-turut terhadap formula 1 (0,1%), yaitu 18,83 ppm memiliki aktivitas antioksidan yang kuat, formula 2 (0,3%) yaitu 9,19 ppm memiliki nilai antioksidan yang sangat kuat, dan formula 3 (0,5%) yaitu 6,51 ppm memiliki nilai antioksidan yang sangat kuat dapat disimpulkan bahwa ekstrak kulit apel hijau (Pyrus malus L.) dapat diformulasi menjadi sediaan face mist stabil sebelum dan sesudah cycling test dan nilai IC50 formula 3 (0,5%) yaitu 6,51 ppm yang memiliki aktivitas antioksidan sangat kuat. Kata Kunci: Kulit Apel Hijau, Antioksidan, DPPH, Spektrofotometri UV-vis
Hubungan Tingkat Kepatuhan dan Kualitas Hidup Pasien Hipertensi di RSUD H. A. Sulthan Daeng Radja Bulukumba: The Relationship Between Adherance and Quality of Life Hypertension Patients in RSUD H. A. Sulthan Daeng Radja Bulukumba Musdar, Tamzil Azizi; Junita, Nurfitria; Asjur, Asti Vebriyanti; Saputro, Syaifullah; Hasmar, Wahyu Nuraini; Santi, Elvira; Ikhsan, Mifta Khaerti; Latu, Saparuddin; Supardi, Nurjannah; Firdaus, Firdaus
Jurnal Sains dan Kesehatan Vol. 6 No. 4 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i4.2151

Abstract

Hypertension is the fourth cause of premature death in several developed and developing countries. The success rate of therapy is greatly influenced by the level of compliance in the treatment of hypertension. This study aims to determine the level of compliance and quality of life of hypertension patients at RSUD H.A Sulthan Daeng Radja Bulukumba. The research was carried out in an observational manner with a descriptive analysis design and cross-sectional data collection, namely the Hypertension Patient Questionnaire. The method for collecting data for this research is in the form of secondary data, namely by asking questions to patients and then analyzing them qualitatively, including name, age, gender, education and occupation. The results of the study showed that the age that most experienced hypertension was age ?60 with a percentage of (41.8%), the largest gender was male, totaling 29 people with a percentage of (52.7%), with the highest level of education. is elementary school, numbering 22 people with a percentage of (39.6%), and the highest employment status is farmers, numbering 38 people with a percentage of (69.1%), thus hypertension is mostly experienced by male patients, age category, education level, and occupation are very influential based on knowledge which is in line with the literature Keywords:          Hypertension, Adherance, Quality of Life, Questionnaiare   Abstrak Hipertensi menjadi penyebab keempat kematian dini di beberapa negara maju dan berkembang. Tingkat keberhasilan terapi sangat dipengaruhi oleh tingkat kepatuhan dalam pengobatan penyakit hipertensi. Penelitian ini bertujuan untuk mengetahui Tingkat Kepatuhan dan Kualitas Hidup Pasien Hipertensi di RSUD H.A Sulthan Daeng Radja Bulukumba. Penelitian dilakukan dengan cara observasional dengan rancangan analisis deskriptif dan pengambilan data secara cross sectional yaitu kuesioner Pasien Hipertensi. Cara pengumpulan data penelitian ini berupa data sekunder yaitu dengan menggunakan pertanyaan pada pasien kemudian dianalisa secara kualitatif yang meliputi nama, umur, jenis kelamin, pendidikan, dan pekerjaan. Hasil penelitian menunjukkan bahwa umur yang paling banyak mengalami penyakit hipertensi yaitu umur ?60 dengan persentase sebesar (41,8%), jenis kelamin terbanyak adalah laki-laki yang berjumlahkan 29 orang dengan persentase sebesar (52,7%), pada tingkat pendidikan terbanyak adalah SD yang berjumlah 22 orang dengan persentase sebesar (39,6%), dan pada status pekerjaan terbanyak yaitu petani yang berjumlah 38 orang dengan persentase sebesar (69,1%), dengan demikian penyakit hipertensi yang paling banyak dialami oleh pasien laki-laki, kategori umur, tingkat pendidikan, serta pekerjaan sangat berpengaruh dengan dilandasi pengetahuan dimana sejalan dengan literatur Kata Kunci:         Hipertensi, Kepatuhan dan Kualitas Hidup, Kuesioner
Evaluasi dan Hubungan Ketepatan Penggunaan Obat Anti Tuberkulosis Lini 1 terhadap Karakteristik Pasien Rawat Jalan di Rumah Sakit Umum Daerah X: Evaluation and Correlation of the Appropriateness of the Use of First-Line Anti-Tuberculosis Drugs to the Characteristics of Outpatients at X Regional General Hospital Musdar, Tamzil Azizi; Hasmar, Wahyu Nuraini; Azis, Muhammad Israwan; Zuchrullah, Mukhtasyam; Saputro, Syaifullah; Kurniati, Kurniati; Ihsan, Mifta Khaerati; Supardi, Nurjannah; Santi, Elvira; Asjur, Asti Vebriyanti
Jurnal Sains dan Kesehatan Vol. 7 No. 6 (2025): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v7i6.2552

Abstract

Tuberculosis is an infectious disease that attacks the respiratory organs (lungs). This study aims to determine the characteristics of the use of first-line anti-tuberculosis drugs (OAT) and evaluate the use of OAT based on the 2019 Tuberculosis Management Guidelines and analysis of the relationship between patient characteristics and treatment outcomes. Data collection was retrospective, with a sample size of 91 Patient Medical Records. The results showed that the most common patient characteristics were male (57.1%), age 46-55 years (24.2%), weight 38-54 kg (53.8%), with working status (52.7%), without comorbidities (89%), new patient type (92.3%), type of OAT category 1 (100%), unsuccessful treatment results (54.9%). Evaluation of OAT use was 100% correct indication, correct patient, and correct drug. While the correct dose (97.8%), correct duration of treatment (41.8%). The relationship analysis obtained age factors (p = 0.04), duration of treatment (p = 0.001) have a significant relationship to treatment outcomes, while gender (p = 0.301) and the number of P.PK (p = 0.733) both do not have a significant relationship to treatment outcomes. Keywords:          TB, Evaluation of OAT Use, X Hospital   Abstrak Penyakit Tuberculosis merupakan penyakit infeksi menular yang menyerang organ pernafasan (paru-paru). Penelitian ini bertujuan untuk mengetahui karakteristik penggunaan obat anti tuberkulosis (OAT) lini 1 dan mengevaluasi penggunaan OAT berdasarkan Pedoman Tatalaksana Tuberkulosis tahun 2019 serta analisis hubungan antara karakteristik pasien terhadap hasil pengobatan. Pengumpulan data secara retrospektif, jumlah sampel sebanyak 91 Rekam Medik Pasien. Hasil penelitian menunjukkan karakteristik pasien terbanyak yaitu berjenis kelamin laki-laki (57,1%), usia 46-55 tahun (24,2%), berat badan 38-54 kg (53,8%), dengan status bekerja (52,7%), tanpa penyakit penyerta penyerta (89%), tipe pasien baru (92,3%), jenis OAT kategori 1 (100%), hasil pengobatan tidak berhasil (54,9%). Evaluasi penggunaan OAT 100 % tepat indikasi, tepat pasien, dan tepat obat. Sedangkan tepat dosis (97,8%), tepat lama pengobatan (41,8%). Analisis hubungan diperoleh faktor usia (p=0,04), lama pengobatan (p=0,001) memiliki hubungan yang signifikan terhadap hasil pengobatan, sedangkan jenis kelamin (p=0,301) dan banyaknya penyakit penyerta kronis (P.PK) (p=0,733) keduanya tidak memiliki hubungan signifikan terhadap hasil pengobatan. Kata Kunci:         TBC, Evaluasi Penggunaan OAT, RSUD X
Co-Authors Abdul Malik Iskandar Adriandy Saleh Aisyah Nur Sapriati Andi Ade Ula Saswini Andi Meinar Dwi Rantisari Asjur, Asti Vebriyanti Asnita Virlayani, Asnita Asti Vebriyanti Asjur Asti Vebriyanti Asjur Asti Vebriyanti Asjur Asty Vebrianty Asjur Azis, Muhammad Israwan Bakri, Alfiyani Besse Yuliana Besse Yuliana Dwidayati, Ari Elvira Santi Elvira Santi Firdaus Firdaus Fitrianingsih, Julia Flora Yulen Pia Rumlus Hasmar, Wahyu Nuraini Hilmiati Wahid Ihsan, Mifta Khaerati Ikhsan, Mifta Khaerati Ikhsan, Mifta Khaerti Junita, Nurfitria Kurniati Kurniati Lestiono Lestiono Lichijati Lichijati Mifta Khaerati Ikhsan Mifta Khaerati Ikhsan Muhammad Thariq Nadhafi Mukhtasyam Zuchrullah Putra, Kevin Gilberth Roganda Ramadani, Ananda Rosmiati Anggraini Rahman Safarudin Safarudin Santi, Elvira Saparuddin Latu Saputro, Syaifullah Setiawan, Prayitno Suhartini Suhartini Suhenro, Suhenro Sukara, Muhammad Akmal A. Supardi, Nurjannah Syaifullah Saputro Syaifullah Saputro Syamsuryanita Syamsuryanita Umi Athiyah Yunita Nita