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All Journal Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Jurnal Farmasi Indonesia Indian Journal of Forensic Medicine & Toxicology Poltekita: Jurnal Pengabdian Masyarakat Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Komunitas Farmasi Nasional Borneo Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian
Ratna Widyasari
Akademi Farmasi Yarsi Pontianak
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health

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Challenges in Maternal and Child Health Routine Data Administration in Indonesia: A Qualitative Study Arief Priyo Nugroho; Diyan Effendi; Zulfa Auliyati Agustina; Asep Kusnali; Siti Maimunah; Irfan Ardani; Ratna Widyasari
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16795

Abstract

Background: Maternal and child health (MCH) routine data is essential in making a good health-relatedpolicy. However, the quality of MCH routine data in Indonesia is doubted, and thus the Indonesian governmentrelies heavily on the survey data for policymaking. This condition raises questions about where the problemsexist in routine data recording stages. This study aims to explore the barriers and strategies of MCH routinedata recording by the administrators in the primary healthcare center.Method: This study was qualitativeresearch conducted in Buru Regency, Ambon City, Purworejo Regency, and Surakarta City from May toNovember 2020. The data collections were intended to understand administrators’ efforts to deal with the datarecording problems. Data triangulation was performed through in-depth interviews with primary healthcarecenter staff and observations on daily routine data administration practices.Results: The study demonstratedchallenges in the MCH routine data administration context. The first problem is behavioral contexts lead toincorrect input and delay data submission. Second, technical determinant shows the lack of integration thatleads to repetitive data recording and data fragmentation. The third was the organizational problem suchas lack of inter and intra-departmental coordination in data sharing, infrastructure, and human resourceshortage.Conclusion: The findings elucidate the problem of administrative structures in the implementationof routine data policy. A comprehensive response to cope with routine data policy implementation contextis needed. Existing maternal and child healthcare routine data requires structural administration refinementthat provides a context for implementing reliable routine data recording of maternal and child health.
EFEKTIVITAS EKSTRAK ETANOL KULIT JERUK MANIS (Citrus x aurantium L.) SEBAGAI LARVASIDA TERHADAP LARVA NYAMUK Aedes aegypti Ratna Widyasari; Fenny Oktaviyeni; Rivo Maghfirandi
Jurnal Insan Farmasi Indonesia Vol 1 No 1 (2018)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Penelitian ini dilakukan untuk mengetahui efektivitas ekstrak etanol kulit jeruk manis (Citrus x aurantium L.) sebagai larvasida Aedes aegypti. Penelitian ini merupakan penelitian in vitro yang dilakukan secara eksperimen dengan 6 kelompok perlakuan yang tiap kelompok berisi 25 ekor larva Aedes aegypti instar III. Uji dilakukan selama 24 jam dengan 3 kali pengulangan dengan konsentrasi berbeda secara berurutan yaitu : 0,2%, 0,4%, 0,6%, 0,8%, dan 1%, dan juga dengan kontrol positif (abate). Hasil penelitian menunjukkan persentase mortalitas larvasida Aedes aegypti yang dibunuh oleh ekstrak etanol kulit jeruk dengan konsentrasi 0.2%, 0,4%, 0,6%, 0,8% dan 1%  secara berurutan adalah 77,3% 85,3%, 89,3%, 100% dan 100%. Hasil penelitian menunjukkan bahwa konsentrasi 0,8% ekstrak etanol kulit jeruk manis (Citrus x aurantium L.) memiliki efektivitas dalam membunuh larva Aedes aegypti. Nilai Lethal concentration (LC50) yang diperoleh sebesar 0,20 % dan Nilai Lethal time (LT50) yang didapat yaitu 9,185 jam.
PENETAPAN KADAR FLAVONOID TOTAL EKSTRAK ETANOL KULIT BATANG SAWO (Manilkara zapota (L.)) SECARA SPEKTROFOTOMETRI UV-VISIBEL Ratna Widyasari; Dina Yuspita Sari
Jurnal Insan Farmasi Indonesia Vol 4 No 2 (2021): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v4i2.828

Abstract

Sawo (Manilkara zapota (L.)) is one of the plants that can be used in traditional medicine. Sawo bark contains secondary metabolites of flavonoids, saponins, tannins, and phenolics. This study aims to determine the total flavonoid content in the ethanol extract of sapodilla stem bark. Determination of total flavonoid content using a colorimetric method using AlCl3 reagent. Determination of total flavonoid using UV Visible Spectrophotometry at a maximum wavelength of 417.50 nm and total flavonoid expressed in QE (Quercetin Equivalent).. The results showed that the total flavonoid content contained in the ethanol extract of the Sawo Bark (Manilkara zapota (L.)) was 1,095 mgQE/g.
Uji Toksisitas Akut Ekstrak Metanol Kulit Buah Jeruk Sambal (Citrus microcarpa Bunge) Terhadap Larva Artemia salina L. Dengan Metode Brine Shrimp Lethality Test (BSLT) Ratna Widyasari; Dina Yuspitasari; Wilda Wildaniah; Rosi Cahayuni Wahida
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 3 No 1 (2018)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (783.893 KB) | DOI: 10.37874/ms.v3i1.64

Abstract

Tanaman jeruk sambal (Citrus microcarpa Bunge) merupakan salah satu tanaman yang banyak terdapat di Kalimantan Barat. Kulit buah jeruk sambal mempunyai aktivitas antioksidan kuat dan aktivitas antimikroba, hal ini berkaitan erat dengan kandungan senyawa metabolit sekunder yaitu flavonoid, alkaloid dan polifenol, dimana senyawa ini berpotensi sitotoksik. Tujuan dari penelitian ini adalah untuk mengetahui apakah ekstrak metanol kulit jeruk sambal bersifat sitotoksik dengan metode Brine Shrimp Lethality Test (BSLT) dan mengetahui nilai LC50 yang dihasilkan. Penelitian eksperimental ini menggunakan ekstrak metanol kulit jeruk sambal dengan pembagian konsentrasi 1000 µg/ml, 750 µg/ml, 500 µg/ml, 250 µg/ml, 100 µg/ml, dan 0 µg/ml dimana pada masing-masing konsentrasi diletakkan 10 ekor larva Artemia salina L. Data kematian larva dikumpulkan dan dianalisis dengan metode analisis probit. Berdasarkan hasil dari analisis regresi linier menunjukkan nilai LC50 dari ekstrak metanol kulit jeruk sambal adalah 234,42 µg/ml.. Hasil penelitian ini menunjukan bahwa ekstrak metanol kulit jeruk sambal bersifat sitotoksik yang ditunjukkan dengan harga LC50 < 1000 µg/ml.
PENETAPAN KADAR FLAVONOID TOTAL EKSTRAK METANOL KULIT JERUK SAMBAL SECARA SPEKTROFOTOMETRI UV-VISIBEL RATNA WIDYASARI; Fadli Fadli; Sri Handayani
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 4 No 2 (2020)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1704.78 KB) | DOI: 10.37874/ms.v4i2.129

Abstract

Jeruk Sambal (Citrus microcarpa Bunge) seringnya dimanfaatkan sebagai tanaman obat tradisional di Kalimantan Barat, seperti antioksidan dan antibakteri dikarenakan adanya senyawa flavonoid dan polifenol. Penelitian ini bertujuan untuk menentukan kadar flavonoid total dari ekstrak metanol kulit jeruk sambal. Penentuan kadar flavonoid total menggunakan metode spektrofotometri UV-Visibel dengan kuersetin sebagai pembanding. Pengukuran panjang gelombang maksimum kuersetin dilakukan pada panjang gelombang 380 nm – 780 nm dan diperoleh panjang gelombang maksimum kuersetin pada 432 nm. Kadar flavonoid total dihitung dengan persamaan regresi linear y = 0,0068 x + 0,1132 dengan koefisien relasi R2 = 0.9712 yang diperoleh dari kurva kalibrasi kuersetin. Hasil skrining fitokimia menunjukkan kulit jeruk sambal mengandung flavonoid dengan kadar flavonoid total sebesar 0,3324 mg/g.Kata kunci:  Kulit Jeruk Sambal, Penetapan Kadar, Flavonoid, Spektrofotometri UV-Visibel
UJI AKTIVITAS ANTIPIRETIK EKSTRAK ETANOL KULIT JERUK MANIS (Citrus x aurantium L) TERHADAP TIKUS PUTIH (Rattus novergicus) JANTAN GALUR WISTAR YANG DIINDUKSI PEPTON 5% Ratna Widyasari; Ratika Ratiningsih
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 2 No 2 (2017): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (218.233 KB) | DOI: 10.36387/jiis.v2i2.100

Abstract

Kulit jeruk manis (Citrus x aurantium L) mengandung zat flavonoid yang mampu menghambat prostaglandin sehingga mempunyai aktivitas sebagai antipiretik. Penelitian ini bertujuan untuk menguji aktivitas antipiretik kulit jeruk manis (Citrus x aurantium L) terhadap tikus putih jantan galur Wistar yang diinduksi pepton 5%. Penelitian ini merupakan penelitian ekperimental dengan rancang acak lengkap. Hewan uji yang digunakan adalah tikus putih jantan galur Wistar sebanyak 15 ekor dengan berat badan 150 – 200 g. Hewan uji dibagi 5 kelompok yaitu kontrol negatif (suspensi Na.CMC 1%), kontrol positif (suspensi parasetamol) dan kelompok uji yaitu pemberian ekstrak kulit jeruk manis (Citrus x aurantium L) dengan konsentrasi 0,5%, 0,75% dan 1%. Pengukuran suhu dilakukan sebelum pemberian pepton 5%, 1 jam setelah pemberian pepton 5% dan 30 menit sekali setelah perlakuan sampai menit ke – 240. Data yang diperoleh dianalisis dengan menggunakan uji anova dan uji LSD (Least significant different). Kesimpulan dari penelitian ini bahwa ekstrak etanol kulit jeruk manis (Citrus x aurantium L) mempunyai aktivitas antipiretik pada tikus putih jantan galur Wistar dan pada konsentrasi 1% memiliki kemampuan aktivitas sebagai antipiretik
STUDI PENGEMBANGAN INSTRUMEN EDUKASI UNTUK MENURUNKAN RISIKO PCOS (Polycystic Ovary Syndrome) PADA WANITA DENGAN OBESITAS Ratna Widyasari; Adhisty Kharisma Justicia; Pinda Hutajulu
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (120.593 KB) | DOI: 10.36387/jiis.v5i1.391

Abstract

Women with obesity would experience an increase in lipid. These lipids would be accumulated in the visceral part of the body caused anovulation that is part of the menstrual disorder called polycystic ovary syndrome (PCOS). This study aims to know factors that could affect obese women to change their lifestyle and to develop an instrument to educate obese women to decrease the risk of PCOS. This study consisted of three steps. In the first step, the obese woman was evaluated qualitatively using semi-structured interviews to know their education needs. In the second step, the education instrument was developed based on their education need. In the third step, the instrument education that had been developed was evaluated. The result showed that the kind of factors affecting obese women to change lifestyle was patient inside-factors and patient outside-factor (environment). Most of the patients had low knowledge about the disease and the cure causing misperception and uncompliance. Therefore, the education instrument was developed using the booklet. The result of the evaluation instrument showed that the booklet that had been developed could increase patient knowledge o change patient uncompliance behavior.
Formulasi Hair Tonic dari Ekstrak Etanol, Fraksi Etanol, dan Fraksi Kloroform-Metanol Kayu Secang (Caesalpinia sappan L.) Dina Yuspita Sari; Ratna Widyasari; Weni Puspita
Jurnal Farmasi Indonesia Vol 18 No 2 (2021): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v18i2.954

Abstract

Secang wood (Caesalpinia sappan L.) has been used as an antioxidant in cosmetic products. The bioactive compound contained in secang wood are brazilin, brazilein, 3´-O-methylbrazilin, sappanone, chalcone, and sappankalkon as secondary metabolite components. This study aims to formulating hair tonic from extracts and fractions of secang wood and to determine the quality of hair tonic formulas using ethanol extract (Eet), ethanol fraction (Fen), and chloroform-methanol fraction (Fkm) of secang wood. The extraction process was carried out using maceration with 96% ethanol as ellent, after that extact partitioned using n-hexane. Fen was then applied using vacuum column chromatography using chloroform, chloroform: methanol (5:1), and methanol as eluent. Eet, Fen, and Fkm of secang wood were then formulated. Hair tonic evaluation includes organoleptic test, determination of pH value, viscosity determination, homogeneity test, and hair growth activity. The results showed that the three hair tonic formulas produced red-orange color, smelled aromatic in solution form, had a pH of 7, were homogeneous, had a viscosity of 3 cps, and showed activity on hair growth and hair weight of rabbits. FIII gave significantly different results from negative control (p <0.05) on rabbit hair length data on day 30, so ii can be concluded that FIII shows the best activity. All three formulas were qualify according to standard requirements and has activity on hair growth.
UJI AKTIVITAS ANTIPIRETIK EKSTRAK DAUN SISIK NAGA(Pyrrosia piloselloides (L.) M.G. Price) TERHADAP TIKUS PUTIH (Rattus norvegicus) JANTAN GALUR WISTAR YANG DIINDUKSI PEPTON 5% Ratna Widyasari; Dina Yuspitasari; Fadli Fadli; Athiah Masykuroh; Winda Tahuhiddah
Jurnal Ilmu Farmasi dan Farmasi Klinik Jurnal Ilmu Farmasi & Farmasi Klinik Vol 15 No 1 Juni 2018
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (270.672 KB) | DOI: 10.31942/jiffk.v15i01.2169

Abstract

INTISARI  Demam adalah keadaan ketika suhu tubuh meningkat melebihi suhu tubuh normal. Demam terjadi karena pelepasan  pirogen  dari dalam leukosit yang sebelumnya telah terangsang oleh pirogen  eksogen yang dapat berasal dari mikroorganisme atau merupakan suatu hasil reaksi imunologik yang tidak berdasarkan suatu infeksi. Sementara itu, banyak  negara telah mengembangkan pengobatan menggunakan herbal. Salah satu usaha yang dilakukan adalah dengan penggunaan obat tradisional. Penelitian ini bertujuan untuk membuktikan bahwa daun Sisik Naga (Pyrrosia piloselloides  (L.) M.G Price) dengan konsentrasi 0,062%, 0,125% dan 0,25% memiliki aktivitas antipiretik dengan menggunakan penginduksi demam  Pepton  5%. Penelitian ini merupakan penelitian eksperimental dengan Rancang Acak Lengkap (RAL). Pengukuran suhu rektal tikus menggunakan termometer  infra red. Hewan uji dibagi menjadi 5 kelompok yaitu kelompok kontrol negatif (suspensi Na-CMC 1%), kelompok kontrol positif (suspensi parasetamol) dan kelompok uji yaitu pemberian ekstrak daun sisik naga 0,062%, 0,125% dan 0,25%. Data yang diperoleh dianalisis dengan  menggunakan uji anova dan uji LSD (Least Significant Different). Hasil dari penelitian ini bahwa ekstrak daun sisik naga (Pyrrosia piloselloides  (L.) M.G Price) konsentrasi 0,25% mempunyai aktivitas antipiretik pada tikus putih (Rattus norvegicus) jantan galur wistar. Kata kunci: Antipiretik, Daun Sisik Naga (Pyrrosia piloselloides (L.) M.G Price), Pepton 5%   ABSTRACT  A fever is a condition when the body temperature rises beyond the normal body temperature. Fever occurs due to the release of pyrogytes from within leukocytes that have previously been stimulated by exogenous pyrogens that may originate from microorganisms or are a result of immunologic reactions that are not based on an infection. Meanwhile, many countries have developed treatments using herbs. One of the efforts done is with the use of traditional medicine. This study aims to prove that the leaves of the Dragon Scales (Pyrrosia piloselloides (L.) M.G Price) with concentrations of 0.062%, 0.125% and 0.25% have antipyretic activity using Pepton fever induction 5%. This research is an experimental research with Completely Random Design (RAL). Rectal temperature measurements of mice using infra red thermometer. Test animals were divided into 5 groups: negative control group (1% Na-CMC suspension), positive control group (paracetamol suspension) and the test group were 0.062%, 0.125% and 0.25%. The data obtained were analyzed using anova test and LSD (Least Significant Different) test. The results of this study showed that the extract of leaf scales (Pyrrosia piloselloides (L.) M.G Price) concentrations of 0.25% had antipyretic activity in white rats (Rattus norvegicus) male wistar strain. Keywords: Antipyretics, Leaf Scales Dragon (Pyrrosia piloselloides (L.) M.G Price), Pepton 5%
Pencegahan Stunting Melalui Pelatihan Pembuatan Sirup Kayu Secang dan Jeruk Sambal Kepada Ibu PKK Desa Pal IX, Kalimantan Barat Dina Yuspita Sari; Ratna Widyasari
Poltekita: Jurnal Pengabdian Masyarakat Vol. 4 No. 3 (2023): Juli-September
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/pjpm.v4i3.1818

Abstract

Desa Pal IX is one of the villages in Kecamatan Sungai Kakap, Kubu Raya Regency which is affected by stunting cases with a stunting case percentage of around 12.7 percent. Sappan wood and limau citrus contain micronutrient compounds in the form of bioactive phenolic compounds and flavonoids, as well as macronutrients in the form of fats and carbohydrates. The aim of implementing this PkM is to provide education and training in making syrup from processed sappan wood and limau citrus as a macro and micro nutrient intake for handling stunting cases in Pal IX village. In general, the stages and planned activities that carried out at this PkM are preparation for activities, implementation of activities, monitoring and evaluation. The method used is the material explanation followed by training on making syrup and how to pack it to produce syrup. The results obtained are processed syrup products from sappan wood and limau citrus. In addition, there was an increase in the average score before and after the workshop, namely an increase in knowledge from a score of 30 to 68.4. Meanwhile, the results of the activity evaluation gave an index value of 86.5%, in the very satisfied category. The workshop activities were able to provide education and skills for PKK organisation in Pal IX Village in recognizing the potential of processed sappan wood and limau citrus syrup in preventing and treating stunting and making syrup product that is rich in macro-micro nutrients.
Co-Authors Arief Priyo Nugroho Asep Kusnali Athiah Masykuroh Dina Yuspita Sari Dina Yuspita Sari Dina Yuspitasari Diyan Effendi Fadli Fadli Fadli Fadli Fenny Oktaviyeni Indri Astuti Irfan Ardani Justicia, Adhisty Kharisma Pinda Hutajulu Puspita, Weni Ratika Ratiningsih Rivo Maghfirandi Rosi Cahayuni Wahida Sanitasari Siti Maimunah Sri Handayani Wilda Wildaniah Winda Tahuhiddah Zulfa Auliyati Agustina