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All Journal Acta Interna : The Journal of Internal Medicine Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Medical Journal of Indonesia Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Journal of Community Empowerment for Health
Anggraeni, Vita Yanti
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Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Acta Interna : The Journal of Internal Medicine

 1 
Correlation Between Systemic Immune-Inflammation Index and Depression in Patient with Heart Failure Reduced Ejection Fraction in Sardjito Hospital Yogyakarta Somba, Imanuel Maryo; Sofia, Noor Asyiqah; Anggraeni, Vita Yanti
Acta Interna The Journal of Internal Medicine Vol 13, No 1 (2024): Acta Interna The Journal of Internal Medicine
Publisher : Faculty of Medicine Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/actainterna.101285

Abstract

Background. Depression is highly prevalent in patients with heart failure reduced ejection fraction (HFrEF). The pathophysiology between these two conditions is related to the inflammation process, therefore some inflammatory markers can be used to assess those conditions. In recent years, the systemic immune-inflammation index (SII) has been developed as a simple and inexpensive indicator of inflammation. Unfortunately, we did not find any study that assessed the correlation between SII and depression in patients with HFrEF.Objective. To investigate the correlation between SII and depression in patients with HFrEF in Sardjito Hospital YogyakartaMethods. This was a cross-sectional study on patients with HFrEF in Sardjito Hospital between February 2023 and May 2023. The normality test was carried out using the Shapiro-Wilk test. Bivariate analysis was carried out using the Spearman correlation test. The result was considered statistically significant when p-value <0.05. Multivariate analysis was carried out using multiple linear regression test.Results. There were 47 HFrEF patients with depression. There was a significant relationship between SII and depression scores from the Spearman Correlation test results of SII with depression scores, with p=0.009. The result showed that the higher the SII, the higher the depression score. The correlation coefficient between the two variables was r=0.375, showing that the correlation was in the weak category.Conclusion. There is a positive correlation between the systemic immune-inflammation index and depression in patients with heart failure reduced ejection fraction.
Co-Authors Adhikara, Imam Manggalya Adyarini, Dwita Dyah Akbar, Adrianus Akhmadi Akhmadi Ambari, Ade Meidian Anandini, Hesti Anggoro Budi Hartopo Annisa Rachmawati Arityanti, Dean Arjuna, Tony Badai Bhatara Tiksnadi Cholid Tri Tjahjono Desandri, Dwita Rian Dwiputra, Bambang Eko Ariwibowo, Eko Ema Madyaningrum Erwan, Nabila Erina Febrianora, Mega Fitra, Maha Handayaningsih, Anastasia Evi Hasan, Harris Hergaf, Indah Widyasari Ide Pustaka Setiawan Irsad Andi Arso, Irsad Andi Krevani, Citra Kiki Leo, Benedreky Makes, Indira Kalyana Mawardi, Fitriana Meirizka, Fathina Muhammad Ridwan Noor Asyiqah Sofia Putra, Yasjudan Rastrama Qhabibi, Faqrizal Ria Rahman, Rahma Azzalia Raynaldo, Abdul Halim Riskiyana, Rilani Rita Hamdani Samekto, Perdana Somba, Imanuel Maryo Sujalmo, Puwardi Susanti, Vina Yanti Susilowati, Eliana Syaoqi, Muhammad Tarsidin, Najmi Fauzan Thahadian, Harik Firman Uki Noviana Widyaningsih, Andhika Yasmine Fitrina Siregar