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Complete recovery of severe coronavirus disease 2019 (COVID-19) infection in an obese patient Susanti, Vina Yanti; Anggraeni, Vita Yanti; Akbar, Adrianus; Leo, Benedreky
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 55, No 3 (2023)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/JMedSci005503202308

Abstract

There is strong evidence indicating that excess adiposity in obesity impacts immune function and host defence. However, almost no known mechanism of how the immune and host defence are affected by the low-grade inflammatory response of the obese has been established. The significance of altered immune response in obesity was presumed to be an independent risk factor for increased morbidity and mortality following the influenza pandemic back in 2009. Similarly, obesity is linked with a higher risk of severity and a worse clinical outcome of severe acute respiratory coronavirus 2 (SARS-COV-2) infection.This case reports a complete recovery of a severe coronavirus disease 2019 (COVID-19) infection despite having morbid obesity aggravated by metabolic syndrome.
IMPROVEMENT OF STUDENTS’ KNOWLEDGE AND READINESS AFTER A SHORT COURSE PILOT OF IPE IN GERIATRIC CARE Setiawan, Ide Pustaka; Mawardi, Fitriana; Riskiyana, Rilani; Arjuna, Tony; Samekto, Perdana; Madyaningrum, Ema; Anggraeni, Vita Yanti; Ariwibowo, Eko
Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Vol 12, No 3 (2023): September
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpki.84788

Abstract

Background: A five-day interprofessional education (IPE) pilot program in geriatric care was introduced to advanced students in clinical rotation. The program focused on providing students with interprofessional experience in managing elderly care. This study aimed to understand the knowledge, readiness, and perception of students from three different professional programs (medical, nursing, and health nutrition students regarding this pilot program Methods: A descriptive quantitative research with open-ended questions was conducted. Wilcoxon analysis was performed to find the difference in students' knowledge and readiness regarding interprofessional collaboration practice before and after the pilot program. Open-ended questions were distributed online to evaluate students' reflections upon participating in the program. Results: There were 27 participants consisting of 8 medical students, 10 nursing students, and 9 health nutrition students involved in this study. The quantitative study found an increase in interprofessional knowledge and readiness (p<0.001). There were also improvements in intra-professional knowledge of the medical, nursing, and dietetics students with p<0.001 in each profession. A descriptive analysis of open-ended questions revealed that teacher competence and good program coordination were regarded as important for the program's success. Students reported that they had a better understanding of the role of other professions in managing patients’ problems. Interprofessional communication was regarded as important to ensure patient safety. Students also learned that interprofessional collaboration in elderly care is important to improve the patient’s quality of life. Conclusion: The pilot IPE program improved both interprofessional and intra-professional knowledge and readiness of the students in geriatric clinical rotation. Moreover, students felt this activity had a positive impact on their understanding of interprofessional collaboration and patient health outcomes.
Correlation Between Systemic Immune-Inflammation Index and Depression in Patient with Heart Failure Reduced Ejection Fraction in Sardjito Hospital Yogyakarta Somba, Imanuel Maryo; Sofia, Noor Asyiqah; Anggraeni, Vita Yanti
Acta Interna The Journal of Internal Medicine Vol 13, No 1 (2024): Acta Interna The Journal of Internal Medicine
Publisher : Faculty of Medicine Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/actainterna.101285

Abstract

Background. Depression is highly prevalent in patients with heart failure reduced ejection fraction (HFrEF). The pathophysiology between these two conditions is related to the inflammation process, therefore some inflammatory markers can be used to assess those conditions. In recent years, the systemic immune-inflammation index (SII) has been developed as a simple and inexpensive indicator of inflammation. Unfortunately, we did not find any study that assessed the correlation between SII and depression in patients with HFrEF.Objective. To investigate the correlation between SII and depression in patients with HFrEF in Sardjito Hospital YogyakartaMethods. This was a cross-sectional study on patients with HFrEF in Sardjito Hospital between February 2023 and May 2023. The normality test was carried out using the Shapiro-Wilk test. Bivariate analysis was carried out using the Spearman correlation test. The result was considered statistically significant when p-value <0.05. Multivariate analysis was carried out using multiple linear regression test.Results. There were 47 HFrEF patients with depression. There was a significant relationship between SII and depression scores from the Spearman Correlation test results of SII with depression scores, with p=0.009. The result showed that the higher the SII, the higher the depression score. The correlation coefficient between the two variables was r=0.375, showing that the correlation was in the weak category.Conclusion. There is a positive correlation between the systemic immune-inflammation index and depression in patients with heart failure reduced ejection fraction.
Simplified AHA/ACC ASCVD risk score implementation in a community-driven approach to initiate statin primary prevention Adhikara, Imam Manggalya; Noviana, Uki; Thahadian, Harik Firman; Putra, Yasjudan Rastrama; Handayaningsih, Anastasia Evi; Adyarini, Dwita Dyah; Akhmadi, Akhmadi; Sujalmo, Puwardi; Widyaningsih, Andhika; Rachmawati, Annisa; Rahman, Rahma Azzalia; Meirizka, Fathina; Anggraeni, Vita Yanti
Journal of Community Empowerment for Health Vol 8, No 1 (2025)
Publisher : Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jcoemph.99182

Abstract

Introduction: One of the objectives of the third Sustainable Development Goal is to lower the prevalence of non-communicable diseases (NCD). Cardiovascular disease (CVD) is one of the NCDs that remains the primary cause of mortality in Indonesia and the rest of the world. The most common CVD is coronary artery disease (CAD). It is crucial to perform risk factor assessments on individuals to facilitate early intervention and prevention. A simple instrument to stratify the population's CVD risk factor is the atherosclerotic cardiovascular disease (ASCVD) Risk Score. This study aims to determine the CAD risk stratification through screening using the ASCVD Risk Score in the Sumberadi, Mlati, Sleman, Yogyakarta populations.Methods: A descriptive study screening for CAD was conducted in a population of Sumberadi aged >15 years, especially aged 40-75 years old. The instrument used in this study was the simplified ASCVD Risk Score. The risk factors for CAD, including blood pressure, blood glucose, and cholesterol, were measured with Indonesian-standard instruments. Data was collected by Posbindu cadres with the aid of the research team. Data was analyzed univariately and presented in the form of a descriptive table.Results: This study's sample is mainly female (87%), and the age average is 48.4 ± 9.6 years old. The samples mostly have normal random blood glucose(RBG) levels (82.6%) with a mean of 117.9 ± 55.2 mg/dL. Meanwhile, the total cholesterol level of the samples is mainly normal (51.6%) with a mean of 201.4 ± 40.2 mg/dL. Four samples of people aged>75 years old needed expert consultation. The remaining 403 samples were classified based on the statin requirements (no statin required, moderate-intensity statin, and high-intensity statin). The 148 samples require moderate-intensity statin, and 64 require high-intensity statin.Conclusion: Half of the subjects in this study were included in the statin-required group. And none of them received statin as CAD primary prevention strategy. Most CAD risk factors are conditions that have no symptoms and remain neglected in the population. Therefore, screening CAD risk in the population with simple and easy instruments is still needed to detect individual CAD-risk profiling early. The screening program enables delegates to the Posbindu's cadres who the expertise had trained. 
Indonesia-INTERASPIRE study: an Indonesian cross-sectional multicenter survey on cardiovascular secondary prevention in coronary heart disease Ambari, Ade Meidian; Hasan, Harris; Dwiputra, Bambang; Desandri, Dwita Rian; Hamdani, Rita; Krevani, Citra Kiki; Syaoqi, Muhammad; Ridwan, Muhammad; Anandini, Hesti; Fitra, Maha; Arso, Irsad Andi; Anggraeni, Vita Yanti; Hartopo, Anggoro Budi; Siregar, Yasmine Fitrina; Tjahjono, Cholid Tri; Tiksnadi, Badai Bhatara; Febrianora, Mega; Tarsidin, Najmi Fauzan; Arityanti, Dean; Qhabibi, Faqrizal Ria; Makes, Indira Kalyana; Susilowati, Eliana; Erwan, Nabila Erina; Hergaf, Indah Widyasari; Raynaldo, Abdul Halim
Medical Journal of Indonesia Online First
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.257833

Abstract

BACKGROUND Cardiovascular disease (CVD) is projected to affect more than 23.3 million people by 2030. Therefore, CVD prevention strategies were established to decrease morbidity and mortality while enhancing overall well-being. The Joint European Societies (JES) guidelines on CVD prevention were developed to enhance preventive cardiology practices. This study aimed to evaluate the adherence to JES guidelines for cardiovascular prevention in routine clinical practice for secondary prevention. METHODS This multicenter cross-sectional study was conducted in 7 centers between August 2020 and June 2021. Patients under 80 years old who had undergone percutaneous transluminal coronary angioplasty, coronary artery bypass graft, percutaneous coronary intervention, or experienced acute coronary syndrome were identified from medical records and interviewed a year later. Descriptive statistics were used to calculate the occurrence of risk variables, medication use, and index events associated with low-density lipoprotein cholesterol (LDL-C), hemoglobin A1c, and blood pressure (BP). RESULTS A total of 402 participants (13.9% female) were interviewed, and their medical records were reviewed. Among the study population, 74.4% had a smoking history, 35.4% had dyslipidemia, 33.1% did not meet the BP target, and only 28.4% achieved the LDL-C target. Additionally, less than half (43.8%) participated in physical activity for >150 min/week. Only 15.6% of the patients among the centers who had scored >8 for the guideline-based target score. CONCLUSIONS Most patients did not meet the guidelines for secondary prevention, primarily due to the high prevalence of dyslipidemia and physical inactivity, although some achieved the LDL-C target.