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Journal : Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan

UJI STABILITAS DAN UJI HEDONIK MASKER GEL PEEL-OFF EKSTRAK DAUN BINAHONG (Anredera cordifolia (Ten.) Steenis) DENGAN VARIAN KONSENTRASI POLIVINIL ALKOHOL (PVA) SEBAGAI FILMING AGENT Tri Puji Lestari; Anisa Riana Putri; Ida Kristianingsih; Evi kurniawati; Fita Sari
Jurnal Ilmiah Manuntung Vol 8 No 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.639

Abstract

Research on the Formulation Physical Stability Test and hedonic test of the peel-off gel mask of binahong Leaf Extract has been conducted. This study aims to determine the best formula of the binahong Leaf Extract peel-off gel mask preparation with PVA as a filming agent. The steps of the procedure in this research include plant determination, sample preparation, making binahong leaves simplicia, making binahong leaves extract, formulation of peel off gel mask evaluation of physical properties, stability test, irritation test and hedonic test. Formulation of binahong Leaf Extract peel-off gel mask were carried out in three formulas with various variations of PVA concentrations of 5%, 5,5%, and 6%. The results of the physical properties test shows that peel-off extract masks of binahong leaves with different concentration variations differ in organoleptic, ph test, and drying time test a statistical data analysis. Based on the results of the stability test using the cycling test method with temperature ± 4̊ C and ± 40̊ C over the course of six cycles. he most stable results of existing tests are F2 and F3 showed no significant differences in each evaluation. Test irritation suggests that the gel peel-off mask was not irritating. From the hedonic test results, panelists prefer F3 compared to other formulas.
AKTIVITAS ANTIBAKTERI DARI SEDIAAN GEL EKSTRAK TERPURIFIKASI KELOPAK ROSELLA TERHADAP BAKTERI Escherichia coli Fita Sari; Ida Kristianingsih; Tri Puji Lestari; Fathul Hidayatul; Yuyun Wulandari
Jurnal Ilmiah Manuntung Vol 9 No 1 (2023): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v9i1.674

Abstract

Natural materials had various types of primary and secondary metabolite compounds that were useful for treating a disease. Plant materials that contain high levels of secondary metabolites could be developed into raw materials for traditional medicines. An example of the development of natural medicine which was in high demand is making traditional medicinal raw materials which have antibacterial properties. These could add to the type of therapy for a disease with smaller side effects. The aim of this study was to determine the activity of the purified extract gel preparation of rosella petals as an antibacterial. The extract was obtained from the maceration method which was then followed by purification. The antibacterial activity test in this study used the well diffusion method. Detection of metabolites by Thin Layer Chromatography (TLC) includes the stationary phase of silica GF254 and the mobile phase Toluene: Acetic acid: Formic acid (6:6:1). The concentration of purified extract of rosella petals for the formulation was 5, 15 and 25%. Data analysis was carried out with the One Way Anova test with a 95% confidence level. The results of the research that the purified extract gel preparation of rosella petals has the potential to inhibit the growth of Escherichia coli bacteria in the sensitive category at a concentration of 25%. The results of a positive phytochemical screening for flavonoid compounds were indicated by the formation of a red-orange color in the test and identification using TLC produced an Rf of 0.85 which has similarities with previous studies. The conclusion of this study was that the ETKR gel preparation with a concentration of 25% was sensitive as an antibacterial
AKTIVITAS ANTIOKSIDAN EKSTRAK DAUN BELUNTAS (Pluchea indica L.) ETANOL 70% DAN ETIL ASETAT MENGGUNAKAN DPPH Hari Purwani, Asih Imulda; Fita Sari; Muhammad Dhika Ramadhan; Herlinda Mawardika
Jurnal Ilmiah Manuntung Vol 10 No 1 (2024): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v10i1.740

Abstract

Pluchea indica L. is a herbaceous plant of the Asteraceae family that has been known to the public as fresh vegetables and traditional medicine since ancient times. This study aims to determine the antioxidant activity of beluntas leaves obtained from the extraction using 70% ethanol and ethyl acetate. The identification of phytochemical screening of beluntas leaves revealed the presence of flavonoids, tanninsand alkaloids. The test of antioxidant activity was performed using the DPPH method as free radical and vitamin C as a comparison. The average IC50 value beluntas leaves in 70% ethanol solvent is 94.06 ppm, in ethyl acetate is