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CONTEXTUAL BASIC CHEMISTRY MODULE DEVELOPMENT FOR BIOLOGY STUDENTS WITH DIVERSE ABILITIES: AN INCLUSIVE AND DIFFERENTIATED LEARNING APPROACH Rizki, Cut Novrita; Helmanda, Cut Mawar; Fajriana, Nurul
Chimica Didactica Acta Vol 13, No 1: June 2025
Publisher : FKIP USK

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jcd.v13i1.45893

Abstract

This study explores the design and development of a contextual basic chemistry module specifically tailored to meet the diverse academic needs of undergraduate biology students. Recognizing the varying educational backgrounds and learning styles of students, the module was systematically created using the ADDIE instructional model, incorporating principles of inclusive pedagogy and differentiated instruction. To enhance accessibility and relevance, the module's content was closely linked to biological concepts and enriched with diverse features such as visual aids, interactive elements, and tasks structured at multiple levels of difficulty. The module was evaluated through a limited-scale implementation involving 25 students from the Tadris Biology program at Muhammadiyah University Aceh, who participated as respondents. Results from this implementation indicated notable improvements in students engagement, conceptual understanding of chemistry, learning motivation, and autonomy. These findings underscore the effectiveness of contextual and inclusive teaching strategies in fostering equitable learning environments and addressing conceptual gaps in interdisciplinary education, particularly for biology students navigating foundational chemistry topics.
Phytochemical Screening of Murraya paniculata L. Leaf Extract Using Methanol, N-Hexane and Ethyl Acetate as Anticholesterol Candidates Aini, Qurratu; Manja, Manja; Rizki, Cut Novrita; Suwarniati, Suwarniati; Fairuz Yusoff, Siti
Biosfer: Jurnal Tadris Biologi Vol 16 No 1 (2025): Biosfer: Jurnal Tadris Biologi
Publisher : UNIVERSITAS ISLAM NEGERI RADEN INTAN LAMPUNG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24042/biosfer.v16i1.27237

Abstract

This study aims to identify the secondary metabolite content and active compounds in plant extracts through phytochemical screening and Gas Chromatography-Mass Spectrometry (GC-MS) analysis. Phytochemical tests revealed the presence of flavonoids, alkaloids, tannins, and terpenoids, which are known for their biological activities including antioxidant and anticholesterol properties. GC-MS analysis identified 21 compounds, with dominant constituents including Phytol, 8-(2,3-Dihydroxy-3-methylbutyl)-7-methoxy-2H-chromen-2-one, and Murrayatin. Among these, Phytol was identified as the primary candidate for anticholesterol activity, supported by literature indicating its role in inhibiting cholesterol biosynthesis. These findings suggest that the extract has potential as a natural anticholesterol agent, although further pharmacological studies are needed to confirm its specific bioactivity. Skrining Fitokimia  Ekstrak Daun Murraya paniculata L. Menggunakan Metanol, N-Heksana dan Etil Asetat sebagai Kandidat Antikolesterol ABSTRAK: Penelitian ini bertujuan untuk mengidentifikasi kandungan senyawa metabolit sekunder serta senyawa aktif dalam ekstrak tumbuhan menggunakan uji fitokimia dan analisis Gas Chromatography-Mass Spectrometry (GC-MS). Uji fitokimia menunjukkan adanya senyawa flavonoid, alkaloid, tanin, dan terpenoid yang diketahui memiliki aktivitas biologis, termasuk sebagai antioksidan dan antikolesterol. Analisis GC-MS mengungkapkan 21 senyawa, dengan senyawa dominan antara lain Phytol, 8-(2,3-Dihydroxy-3-methylbutyl)-7-methoxy-2H-chromen-2-one, dan Murrayatin. Di antara senyawa tersebut, Phytol diidentifikasi sebagai kandidat utama senyawa antikolesterol berdasarkan referensi ilmiah yang mendukung aktivitasnya dalam menghambat biosintesis kolesterol. Hasil ini menunjukkan bahwa ekstrak tumbuhan ini memiliki potensi sebagai agen antikolesterol alami, namun diperlukan uji farmakologis lanjutan untuk mengonfirmasi aktivitas tersebut secara lebih spesifik.