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Kegawat Daruratan dan Treatment Pasien Schizophrenia Dengan Perilaku Kekerasan Berulang : Study Case Hery Wibowo; Islamiyah; Herdaetha, Adriesti; Septiawan, Debree
Dunia Keperawatan: Jurnal Keperawatan dan Kesehatan Vol 10 No 3 (2022): Dunia Keperawatan: Jurnal Keperawatan dan Kesehatan
Publisher : School of Nursing, Faculty of Medicine and Health Science, Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (197.884 KB) | DOI: 10.20527/jdk.v10i3.142

Abstract

 Pendahuluan : Tingkat kejahatan yang dilakukan oleh pasien schizophrenia secara umum lebih rendah biladilakukan treatment dengan benar dan teratur. Tapi pasien dengan schizophrenia bisa sepuluh kali lebihberkomitmen dalam melakukan pembunuhan dari pada populasi umum bila treatment pasien dengan masalahpsikiatri forensik tidak teratur, bahkan cenderung lebih sering melakukan perilaku kekerasan.Tujuan dari kasus ini untuk menjelaskan keberlangsungan terapi dalam mengendalikan perilaku kekerasan.Metode disajikan dengan menampilkan 5 kasus dengan perilaku kekerasan berulang yang dilakukan pasienschizophrenia dengan observasi dan in-dept interview.Hasil : Pada pemeriksaan semua pasien tidak mampu menceritakan kronologis penganiayaan dan perilakukekerasan secara konsisten, rinci dan runtut. Pada pemeriksaan status mentalis ditemukan bentuk fikir tidakrealistis, Isi pikir thought insertion, thought of being control, penilaian realita terganggu, Selama observasipelaku tidak menunjukkan adanya perilaku yang tidak wajar, jarang berinteraksi dengan pasien lain. Semuakasus yang disajikan memiliki riwayat putus treatment 2-3 bulan sebelum terulangnya perilaku kekerasankarena mayoritas kehilangan sosok care giver
Basic Data on Relapse Conditions of Mental Disabilities (People with Mental Disorders) in Kebumen District, Central Java Indonesia Agustin, Ike Mardiati; Yusuf, Munawir; Herdaetha, Adriesti; Wibowo, Agung
Proceedings of the International Conference on Nursing and Health Sciences Vol 5 No 1 (2024): January-June 2024
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/picnhs.v5i1.2783

Abstract

Healing psychosis in people with mental disabilities (People with Mental Disorder) requires a long-term treatment process followed by potential recurrence or relapse with varying causal factors, both internal and external. This research aims to present a database obtained from various sources resulting from identification of mental disability relapse conditions (people with severe mental disorders) in Kebumen district. The research method uses analytical descriptive using a survey approach to the community Public health center database in the Kebumen district on 4545 sufferers of serious mental disorders who had been treated and received routine treatment at health service facilities, the data was analyzed univariately with frequency distribution. The results of the study showed that of 4545 people with mental disabilities (severe mental disorders) 2692 (64.51%) experienced relapses or recurrences spread across all Public health center areas in Kebumen district with 3 Public health centers that had the highest relapses being at Mirit 265 Public health center (9.84 %) of relapse cases, Sruweng Public health center 249 (9.24%) and Kebumen 1 Public health center 110 (4%). Recommendations from the results of this study can be used as basic data for further efforts to treat relapse or recurrence in people with serious mental disorders.
The Effectiveness of Meloxicam Adjuvant Therapy to Improve Cognitive Function of Schizophrenic Patients Islamy, Nabila Nur Bilqis; Nugroho, I Gusti Bagus Indro; Herdaetha, Adriesti
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 14 No. 2 (2023): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V14I22023.52-56

Abstract

Highlights:1. Schizophrenic patients have cognitive dysfunction.2. Meloxicam, as an adjuvant therapy, can improve cognitive function in schizophrenic patients. AbstractIntroduction: Schizophrenia is a chronic psychotic disorder triggered by genetic and environmental factors such as an inflammatory response. The inflammatory response in schizophrenic patients increases with cognitive decline. Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) group with Cyclo-oxygenase (COX-2) inhibitory activity and can suppress the production of inflammatory cytokines. This study aimed to determine the efficacy of Meloxicam as an adjuvant therapy to improve cognitive function in schizophrenic patients.Methods: This was a quasi-experimental study using a single-blind, pretest–post-test design. The sample size in this study was 34 subjects who had met the inclusion and exclusion criteria. All samples were divided into two groups, namely the treatment group, with as many as 17 subjects receiving additional therapy with Meloxicam 15 mg/day for 4 weeks, and the control group, with 17 subjects. The score of the Schizophrenia Cognition Rating Scale (ScoRS) was assessed before and after therapy. Data analysis used SPSS 25.0. In both groups, the SCoRS score was different.Results: In the treatment group, there was a decrease in the SCoRS score that was greater than in the control group. There was a statistically significant difference with p = 0.002 in decreasing SCoRS scores.Conclusion: In the treatment group, there was a decrease in the SCoRS score that was greater than in the control group. There was a statistically significant difference with p = 0.002 in decreasing SCoRS scores.
The Differences in Adjuvant Therapy Effectiveness Meloxicam and N-Acetylcysteine against Negative Symptoms of Schizophrenia Murda, Banu Kadgada Kalingga; Nugroho, I Gusti Bagus Indro; Herdaetha, Adriesti
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 14 No. 2 (2023): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V14I22023.63-69

Abstract

Highlights:1. Schizophrenic patients can have negative symptoms.2. Adjuvant therapy is needed to assist antipsychotics in reducing the negative symptoms of schizophrenic patients. AbstractIntroduction: Meloxicam and N-Acetylcysteine are examples of drugs with anti-inflammatory effects that have been widely studied, and are considered to reduce negative symptoms of schizophrenia. Both of these drugs are also widely available in Indonesia and can be obtained at an affordable price. This study aimed to analyze the differences in the effectiveness of adjuvant therapy meloxicam and N-Acetylcysteine on negative symptoms of schizophrenic patients. Methods: This was a quasi-experimental study using a single-blind, pretest–post-test design. Determination of the subject used a purposive sampling technique according to the inclusion criteria. This study examined 34 samples and divided them into two groups. In group A, 17 subjects received adjuvant meloxicam therapy of 15 mg/day for 4 weeks; in group B, 17 subjects received adjuvant therapy of N-Acetylcysteine 400 mg/day for 4 weeks. Score assessment was performed using the positive scale, negative scale, and general psychopathology scale (PANSS) negative subscale pre- and post-therapy, then compared the effectiveness. Data analysis used SPSS 25.0.Results: The mean score of the PANSS post-test subscale was negative in the meloxicam adjuvant therapy group 15.58, while for the N-Acetylcysteine adjuvant therapy group was 17.64 with a p-value of 0.009. The mean decrease in the negative subscale PANSS score in the meloxicam adjuvant therapy group was 11.00, while the N-Acetylcysteine adjuvant therapy group was 19.70 with a p-value of 0.000.Conclusion: There was no difference in the effectiveness of adjuvant therapy meloxicam and N-Acetylcysteine in improving negative symptoms of schizophrenic patients.
Effectiveness of Adjuvant Treatment of N-Acetylcysteine on Negative Symptoms and Neutrophil-Lymphocyte Ratio (NLR) in Schizophrenic Patients Ranto, Ipak; Herdaetha, Adriesti; Kusuma, Wijaya
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 14 No. 2 (2023): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V14I22023.70-75

Abstract

Highlights:1. The essence of schizophrenia is the negative symptoms.2. Adding meloxicam can improve the negative symptoms and changes in the NLR in schizophrenic patients. AbstractIntroduction: Schizophrenia is a mental disorder that has a negative symptom domain. Negative symptoms are commonly referred to as the essence of schizophrenia. Treatment of negative symptoms is still considered less than optimal. The ratio of neutrophils and lymphocytes is one of the markers of inflammation. This study aimed to analyze the effectiveness of N-acetylcysteine as adjuvant therapy for improving negative symptoms and changes in the neutrophil-lymphocyte ratio (NLR) in schizophrenic patients. Methods: This was a quasi-experimental study using a single-blind, pretest–post-test design. The subjects were 34 schizophrenic patients who were inpatients at Dr. Arif Zainuddin Regional Mental Hospital (RSJD), Surakarta, from May to July 2020. The subjects were assigned using a purposive sampling technique based on inclusion criteria and received adjuvant N-acetylcysteine therapy at 400 mg/day for 4 weeks. Data collection was obtained from medical records, interviews, field notes, positive scale, negative scale, and general psychopathology scale (PANSS) assessment sheets, and blood NLR examinations. Data analysis used SPSS 25.0.Results: There was a significant difference between the treatment and control groups in reducing negative PANSS subscale measurement after adjuvant N-acetylcysteine treatment. However, there was no significant difference between the control and treatment groups after N-acetylcysteine administration for NLR.Conclusion: The dose of adjuvant therapy N-acetylcysteine given to patients in this study had an effect on decreasing the negative subscale PANSS score.
Intervensi Electroconvulsive Therapy (ECT) pada Skizofrenia Katatonik Muljanto, Rahaju Budhi; Herdaetha, Adriesti; Kusuma, Wijaya; Ahmad, Ahmad
Bima Nursing Journal Vol 6, No 1 (2024): November
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/bnj.v6i1.1717

Abstract

Laporan kasus ini mendokumentasikan intervensi Electroconvulsive Therapy (ECT) pada seorang pria berusia 30 tahun yang didiagnosis dengan skizofrenia katatonik, di mana pengobatan farmakologis tidak memberikan hasil yang memadai. Skizofrenia katatonik merupakan subtipe yang jarang namun parah, ditandai dengan gangguan motorik seperti katalepsi, mutisme, dan gerakan motorik yang tidak teratur. Pasien dalam laporan ini menunjukkan resistensi terhadap obat-obatan antipsikotik, termasuk Haloperidol dan Clozapine, yang mendorong tim medis untuk melakukan ECT sebagai alternatif terapeutik. Prosedur ECT dilakukan dengan pengawasan ketat, dan hasilnya menunjukkan perbaikan signifikan pada gejala katatonik pasien, dengan pengurangan halusinasi dan peningkatan interaksi sosial. Laporan ini menegaskan efektivitas ECT dalam mengatasi gejala katatonik pada kasus skizofrenia yang resisten terhadap pengobatan, serta pentingnya pendekatan individualisasi dalam pengelolaan gangguan ini.
Factors Influence Non-suicidal Self-Injury Behavior among Young Adults Herdaetha, Adriesti; Ismaya, Matius Dimas Reza Dana; Suwito, Joko
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5481

Abstract

Background: Non-suicidal self-injury (NSSI) behavior is increasing among young adults in Indonesia due to the experienced stress. This behavior is influenced by sleep quality, parenting style, and alexithymia mediated by emotional dysregulation. Objectives: To determine the influence of sleep quality, parenting style, and alexithymia on NSSI behavior mediated by emotional dysregulation in the young adult population. Methods: This study used an analytical observational design with a cross-sectional approach. The study subjects consisted of 573 young adult respondents who met the inclusion and exclusion criteria. The study was conducted using a Google Form distributed through social media. Statistical tests were performed using structural equation modeling-partial least square (SEM-PLS). Results: Directly, sleep quality increased NSSI (p=0,000; OS=0,219) and emotional dysregulation (p=0,012; OS=0,076), authoritative parenting style decreased emotional dysregulation (p=0,000; OS=-0,109), authoritarian parenting style increased NSSI (p=0,013; OS=0,125), alexithymia increased emotional dysregulation (p=0,000; OS=0,655), and emotional dysregulation increased NSSI (p=0.000; OS=0.252). Indirectly, through emotional dysregulation mediation, sleep quality increased NSSI (p=0,032; OS=0,019), authoritative parenting style decreased NSSI (p=0,008; β=-0,027), and alexithymia increased NSSI (p=0,000; OS=0,165). Conclusions: Sleep quality, parenting style, and alexithymia influence NSSI behavior directly and indirectly through emotional dysregulation mediation.