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All Journal Medika Kartika : Jurnal Kedokteran dan Kesehatan Jurnal Abdimas Kartika Wijayakusuma Acta Medical and Health Sciences (AMHS)
Roslaeni, Rini
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Journal : Acta Medical and Health Sciences (AMHS)

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The risk factors of coronary heart disease among workers at south cimahi according to the jakarta cardiovascular score Waskito, P.Pujo; Roslaeni, Rini; Wahyu Handini, Rida
ACTA Medical Health Sciences Vol. 2 No. 1 (2023): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

Coronary heart disease is the world’s biggest killer. It is influenced by several risk factors, such as age, gender, blood pressure, body mass index, physical activity, diabetes mellitus, and smoking habit. This study aimed to describe the level of risk factors for coronary heart disease in 10 years according to The Jakarta cardiovascular score. The research used a descriptive method with a cross sectional design. The population of the study was 45 workers in the subdistrict office of South Cimahi. Samples were taken using simple random sampling. The majority of the workers in South Cimahi sub-district are male employees aged 50-54 years old (24.44%). Four people (8.9%) in the population were classified as having hypertension. While the majority, 97.8%, had normal glucose levels. However, only four people included in the category of obesity (8.9%). 51.1% of the employees, or 23 individuals, were smokers. The average workers in the South Cimahi district office had heavy physical activity, namely 24 people (53.3%). Based on The Jakarta cardiovascular score tool, there were 13 respondents who were included in the low-risk category (28.9%), while 26 respondents (57.8%) were included in the medium-risk category, and 6 respondents (13.3%) were at the high-risk category. The Jakarta cardiovascular score ranked the majority of the sub-district office workers in South Cimahi to be in the medium-risk category of developing coronary heart disease; therefore, education and prevention are required. DOI : 10.35990/amhs.v2n1.p21-28 REFERENCE World Health Organization. The Top 10 Causes of Death. 2020. P2PTM Kementerian Kesehatan RI. Apa Itu Penyakit Jantung Koroner (PJK)? Catheterization, R. Abdul, W. Sjahranie. Hubungan Tingkat Pengetahuan dan Kecemasan Pasien. 2020; 2(1):1–7. Pujowaskito P, dkk. P2PTM Kementerian Kesehatan RI. Hari Jantung Sedunia: Jantungmu adalah Jantung Kami Juga. 2019. Kementerian Kesehatan Republik Indonesia. Situasi Kesehatan Jantung. 2014. Dinas Kesehatan Kota Cimahi. Profil Kesehatan Kota Cimahi Tahun 2019. Dinas Kesehatan Kota Cimahi. Profil Kesehatan Kota Cimahi Tahun 2018. Badan Pusat Statistik Kota Cimahi. Kota Cimahi Dalam Angka 2021. BPS Kota Cimahi; 2021. Kecamatan Ceppu. Tugas dan Fungsi Kecamatan. 2021. Kementerian Kesehatan RI. Peringatan Hari Jantung Sedunia 2021: Jaga Jantungmu untuk Hidup yang Lebih Sehat. Nadzir M, Prasetyo A, Fakultas Kedokteran UNEJ. Prediksi Penyakit Jantung Koroner pada PNS Melalui Metode Framingham Risk Score di RSUD dr. Soebandi Jember. 2015. Tiksnadi BB, Afrianti R, Sofiatin Y, Ridha A, Fihaya FY, Roesly RMA, dkk. Gambaran Profil Risiko Kardiovaskular Berdasarkan Skor. Yusvita F, Nandra NS. Deskripsi Tingkat Risiko Penyakit Jantung dan Pembuluh Darah pada Pekerja di PT. Forum Ilmiah X. 2018; 15. Kementerian Kesehatan. Pedoman Pengendalian Faktor Risiko Penyakit Jantung dan Pembuluh Darah. 2016; 98:64–72. Sari YA, Widiastuti, Fitriyasti B. Gambaran Faktor Risiko Penyakit Jantung Koroner di Poliklinik Jantung RSI Siti Rahmah Padang Tahun 2017-2018. 2021. Saraswati D, Lina N. Faktor Risiko Penyakit Jantung di Masyarakat pada Pos Pembinaan Terpadu (Posbindu) Puskesmas Cibeureum. Jurnal Ilmu Kesehatan Masyarakat Gorontalo. 2020; 4(1):1–7. P2PTM Kementerian Kesehatan RI. Apa Definisi Aktivitas Fisik? Rondonuwu R, Tuegeh J, Bahuwa S, Sisfiani D. Aktivitas Fisik dan Penyakit Jantung Koroner. 2020; 1(1):34–41. Yuliani F, Oenzil F, Iryani D. Hubungan Berbagai Faktor Risiko terhadap Kejadian Penyakit Jantung Koroner pada Penderita Diabetes Melitus Tipe 2. Jurnal Kesehatan Andalas. 2014; 3(1):37–40. Savia FF, Mato Rusni S. Pengaruh Merokok terhadap Kejadian Penyakit Jantung Koroner (PJK) di RS dr. Wahidin Sudirohusodo. 2013. Umar F. Perilaku Merokok dan Lingkungan Tempat Tinggal Pasien Rawat Jalan Penyakit Jantung Koroner di Makassar. Media Gizi Masyarakat Indonesia. 2011; 1.
Relationship between D-dimer level and severity in COVID-19 cases at Dustira Hospital Roslaeni, Rini; N Nawangsih, Eka; Judarisa, Tristy
ACTA Medical Health Sciences Vol. 2 No. 2 (2023): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

Coronavirus Disease-2019 (COVID-19) is an emerging disease with clinical symptoms similar to severe pneumonia. It is caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). COVID-19 encompasses various degrees of severity, including mild, moderate, severe, and critical. One of the supporting tests used to detect COVID-19 is the D-dimer test. This cross-sectional study aims to investigate the relationship between D-dimer levels and the severity of COVID-19. The study was conducted at Dustira Hospital in West Java, Indonesia, from September 2022 to January 2023. D-dimer examination utilizes the Sysmex CS-2500 instrument, with a reference value of <0.5 mg/L. A sample of 42 patients was selected using the purposive sampling technique. The results revealed that the majority of confirmed COVID-19 cases were female (59.5%), with the highest proportion in the age groups of 41-50 years and 51-60 years (33.3%). Among the patients, 52.4% had moderate severity, and 64.3% had increased D-dimer levels. The average D-dimer levels in patients with moderate, severe, and critical symptoms were 0.97 mg/L, 2.33 mg/L, and 4.35 mg/L, respectively. The data were analyzed using the Kruskal-Wallis test, which indicated a significant difference in D-dimer levels based on the severity of COVID-19 (p=0.0001). Elevated D-dimer levels occur as a result of SARS-CoV-2 infection, which triggers an exaggerated inflammatory response leading to a cytokine storm. This, in turn, causes endothelial cell dysfunction and stimulates an excessive immune response, resulting in immune cells attacking healthy tissue. The severity of symptoms worsens as the D-dimer level increases. DOI : 10.35990/amhs.v2n2.p81-87 REFERENCE World Health Organization. WHO Official COVID-19 Info [Internet]. 2022 [cited 2022 Jul 17]. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019 Magdalena, Sugiri YJ, Tantular R, Listyoko A. Karakteristik Klinis Pasien COVID-19 di Rumah Sakit Dr. Saiful Anwar, Malang. J Respirol Indones. 2021;41(1):7–14. Susilo A, Rumende CM, Pitoyo CW, Santoso WD, Yulianti M, Herikurniawan H, et al. Coronavirus Disease 2019: Tinjauan Literatur Terkini. J Penyakit Dalam Indones. 2020;7(1):45–67. Kementerian Kesehatan RI. Peta Sebaran Transmisi Lokal dan Wilayah Terkonfirmasi [Internet]. [cited 2022 Jul 18]. Available from: https://infeksiemerging.kemkes.go.id/dashboard/covid-19 Burhan E, Susanto AD, Nasution SA, Eka G, Pitoyo Ceva W, Susilo A, et al. Pedoman Tatalaksana COVID-19. 4th ed. Jakarta: 2022. p. 1–10. Willim HA, Hardigaloeh AT, Supit AI. Koagulopati pada Coronavirus Disease-2019 (COVID-19): Tinjauan pustaka. Intisari Sains Medis. 2020;11(3):749–56. Akbar MNA, Rahardjo AM, Parti DD, Sakinah EN. Analisis Hubungan NLR, D-dimer dan Saturasi Oksigen dengan Derajat Keparahan COVID-19 di RSU Kaliwates Jember. J Agromed Med Sci. 2022;8(1):51–5. Yao Y, Cao J, Wang Q, Shi Q, Liu K, Luo Z, et al. D-dimer as a biomarker for disease severity and mortality in COVID-19 patients: A case control study. J Intensive Care. 2020;8(49):2–11. Nemec HM, Ferenczy A, Iii BDC, Ashley DW, Montgomery A. Correlation of D-dimer and Outcomes in COVID-19 Patients. Am Surg. 2022;88:2115–8. Afandi D. Kaidah dasar bioetika dalam pengambilan keputusan klinis yang etis. Majalah Kedokteran Andalas. 2017;40(2):111–21. Centers for Disease Control and Prevention. Provisional COVID-19 Deaths by Sex and Age. 2023. Neves MT, de Matos LV, Vasques AC, Sousa IE, Ferreira I, Peres S, et al. COVID-19 and aging: Identifying measures of severity. SAGE Open Med. 2021;9:1–6. Liu Y, Mao B, Liang S, Yang JW, Lu HW, Chai YH, et al. Association between age and clinical characteristics and outcomes of COVID-19. Eur Respir J. 2020;55(5). Kurnianto E, Putra DH, Fannya P, Dewi DR. Tinjauan karakteristik pasien dengan kasus positif COVID-19 di Puskesmas Kecamatan Matraman. Indones Health Inf Manag J. 2021;9(2):102–8. Khaerunnisa R, Rumana NA, Yulia N, Fannya P. Gambaran Karakteristik Pasien COVID-19 di Rumah Sakit Mekar Sari Bekasi Tahun 2020–2021. J Manaj Inf Kesehat Indones. 2022;10(1):72. Berger JS, Kunichoff D, Adhikari S, Ahuja T, Amoroso N, Aphinyanaphongs Y, et al. Prevalence and Outcomes of D-Dimer Elevation in Hospitalized Patients With COVID-19. 2020;(Oct):2539–47. Tang N, Li D, Wang X, Sun Z. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost. 2020;18(4):844–7. Roslaeni R. Telaah Pustaka: D-Dimer Pada Pasien COVID-19. Med Kartika. 2022;5(3):332–42. Atmaja KS, Wicaksana AAGOS, Putra IWAS, Putra WWS. Hubungan konsentrasi serum C-Reactive Protein dan D-dimer dengan derajat keparahan dan mortalitas pasien COVID-19. Intisari Sains Medis. 2021;12(2):680. Ardiani S, Tursinawati Y, Wahab Z. Hubungan D-Dimer dengan Ketahanan Hidup Pasien Covid-19 Derajat Berat-Kritis di RSUD Tugurejo Semarang. Health Med J. 2022;5(1):44–9.
Co-Authors Anita Liliana Susanti, Anita Liliana Choerunisa, Towifah F. Choerunisa, Towifah Fauziah Eka Noneng Nawangsih Elly Noer Rochmah, Elly Noer Fathya, Nurul Aida Haeni, Linlin Hasanah, Laila Iriawan, Jusron Isnaeni, Rifat Budi Augustyo Judarisa, Tristy Koswara, Teja Kusuma, Andri Anugerah Linasari, Desy Mardliyah, Emma Mustikasari, Sylvia N Nawangsih, Eka Priyadi, Hendri Putra, Dika Kusuma Rakhmat, Iis Inayati Ratunanda, Susanti Ris Kristiana, Ris Sa'adah, Hindun Salsabila, Salma Syifa Sari, Sylvia Mustika Septiadi, Endry Susanti, Anita L. Wahyu Handini, Rida Waskito, P.Pujo