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All Journal Jurnal Riset Kesehatan Biology, Medicine, & Natural Product Chemistry GANEC SWARA Nutriology: Jurnal Pangan, Gizi, Kesehatan ADMA: Jurnal Pengabdian dan Pemberdayaan Masyarakat Jurnal Kolaboratif Sains Alamtana
Sukanty, Ni Made Wiasty
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Edukasi PHBS dalam Upaya Peningkatan Derajat Kesehatan Masyarakat di Tatanan Rumah Tangga Sukanty, Ni Made Wiasty; Yunita, Lina; Rahmiati, Baiq Fitria; Astawan, Wanda Januar; Septian, Defel
ADMA : Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol 3 No 2 (2023): ADMA: Jurnal Pengabdian dan Pemberdayaan Masyarakat
Publisher : LPPM Universitas Bumigora

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/adma.v3i2.2498

Abstract

Clean and healthy living behavior (PHBS) in the household is one of the government's programs to improve people's welfare. PHBS indicators in homes include using clean water, washing hands with soap and clean water, and using healthy latrines. Lack of knowledge and public awareness of the importance of PHBS and inadequate health support facilities and infrastructure can be a factor causing high rates of morbidity and mortality due to a disease. One of the means of supporting public health is the availability of water sources. The decrease in river water discharge in Lembah Sari Village can affect sanitation related to PHBS in the community. We have conducted PHBS counseling activities in Lembah Sari Village using PowerPoint media, posters, and teaching aids. It was an effort to help people know, want, and practice PHBS. After receiving counseling, the community became more aware of PHBS. The community seemed enthusiastic and participated in practicing washing hands with soap as an indicator of PHBS. This activity is expected to be applied by the community daily.
Pendampingan Pencantuman Informasi Nilai Gizi pada Packaging Madu Trigona Peternak Lebah dalam Meningkatkan Penjualan Yunita, Lina; Sukanty, Ni Made Wiasty; Dewi, Novianty Tysmala; Ariani, Farida
ADMA : Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol 4 No 2 (2024): ADMA: Jurnal Pengabdian dan Pemberdayaan Masyarakat
Publisher : LPPM Universitas Bumigora

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/adma.v4i2.3189

Abstract

Bengkaung Village is a village in the Batulayar District, West Lombok Regency, NTB Province. The great potential of trigona honey bee cultivation in Bengkaung Village can be further developed and supported by the abundant availability of bee feed. Cultivation of Trigona honey bees produces genuine honey which is efficacious for health. Trigona honey bee cultivation is one of the entrepreneurs that can be introduced to the wider community, so that it can increase income. Bengkaung Village is one of the villages that produces honey with good quality, it's just that there is a problem that does not include nutritional value information on the packaging. This is because the packaging design and the inclusion of labeling nutriton fact have an influence on potential buyers to purchase the product. This activity aims to increase knowledge about the function of food labels and how to include information on food labels in accordance with laws and regulations, so partners are expected to be able to understand what information must be included at a minimum and what information is prohibited from being included on food labels so that partners make designs. Food labels that are not only attractive but also in accordance with statutory regulations. This is a solution related to solving problems in Bengkaung Village, especially for Trigona Beekeepers. With the dissemination of packaging design by including information on nutritional value for Trigona honey packaging products, beekeepers get an increase in sales
PROTEIN RAS-LIKE PROTEINS FROM RAT BRAIN SEBAGAI TARGET PENGHAMBATAN PERKEMBANGAN SEL KANKER SUKANTY, NI MADE WIASTY; SAPUTRA, I PUTU BAYU AGUS; ARIANI, FARIDA; YUNITA, LINA; DEWI, NOVIANTI TYSMALA
GANEC SWARA Vol 17, No 4 (2023): Desember 2023
Publisher : Universitas Mahasaraswati K. Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35327/gara.v17i4.661

Abstract

Ras-like proteins from rat brain (Rab) is one of the crucial proteins in the process of intracellular transport. Rab plays a role in delivering vesicles from the donor membrane to the acceptor membrane. Vesicles contain various molecules that are important in cell growth and development. These molecules are generally involved in some signaling pathways. In carrying out its functions, Rab needs to be activated first. The activation process of Rab involves various proteins. Thus, Rab activation and deactivation control are critical to regulating the movement of the transferred molecules. In cancer, there is an uncontrolled activation and deactivation of Rab. Rab's involvement in various signaling pathways by providing molecules needed for growth and development is a basis for increasing the speed of growth and development of cancer cells. Although Rab is not the main factor causing cancer, it can help the development of cancer. So, it can be one of the keys to controlling the transfer of molecules involved in the growth and development of cancer cells. There are several methods related to the activation of Rab for molecular transport. Rab activation inhibition by Rab inhibitors and inhibitors of Rab activating proteins and the use of miRNAs can prevent molecule transport. Thus, control of Rab activation can be an alternative to suppress the growth and development of cancer cells.
EFEKTIVITAS EKSTRAK ETANOL TAUGE (VIGNA RADIATA) DALAM MENINGKATKAN KADAR GLUTATION PEROKSIDASE PADA TIKUS PUTIH (RATTUS NORVEGICUS) YANG DIINDUKSI TOLUENA SUKANTY, NI MADE WIASTY; SAPUTRA, I PUTU BAYU AGUS
GANEC SWARA Vol 17, No 4 (2023): Desember 2023
Publisher : Universitas Mahasaraswati K. Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35327/gara.v17i4.673

Abstract

Toluene is an industrial volatile compound that is easily inhalable. Excessive exposure to toluene causes health problems because it can increase ROS and cause oxidative stress. Bean sprouts are a plant rich in antioxidants to ward off ROS. The known effectiveness of bean sprout ethanol in increasing antioxidants is uncertain. This study aims to determine the potency of ethanol extract from bean sprouts in increasing the GPX antioxidant levels of white rats induced by toluene. The sample consisted of 30 mice divided into groups K-, K+, P1, P2, and P3. Ethanol extract of bean sprouts is given orally at a dose of 50 mg/200 g BW (P1), 100 mg/200 g BW (P2), and 200 mg/200 g BW (P3) in samples that have been induced before by 0.2 mL toluene/200 g BB for 30 days. MDA and GPX levels were measured using ELISA and tested statistically using the One Way Anova test with α = 0.05. The test results showed that there were no significant differences in MDA levels in all groups (p > 0.05), and there were outstanding differences in GPX levels between the K+ and K- groups (p = 0.001) and P2 (p = 0.009). Based on these results, administering ethanol extract of bean sprouts at 100 mg/200 g BW can increase GPX levels in rats induced by toluene.
Status Gizi dan Kepatuhan Konsumsi Tablet Fe serta Kejadian Anemia Pada Ibu Hamil Utami, Syintia; Naktiany, Wayan Canny; Sukanty, Ni Made Wiasty
Nutriology : Jurnal Pangan,Gizi,Kesehatan Vol 5 No 1 (2024): April 2024
Publisher : Program Studi Gizi, Universitas Bumigora

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/nutriology.v5i1.3513

Abstract

Faktor penyebab anemia pada ibu hamil diantaranya sosial ekonomi, pengetahuan, pendidikan, dan budaya. Ketidakpatuhan ibu hamil dalam mengonsumsi tablet Fe juga dapat meningkatkan risiko terkena anemia. Ibu hamil berstatus gizi kurang cenderung lebih berisiko mengalami anemia Tujuan penelitian ini untuk mengetahui hubungan status gizi dan kepatuhan konsumsi tablet Fe dengan kejadian anemia. Rancangan penelitian ini berupa studi analitik dengan metode cross-sectional. Populasi pada penelitian ini adalah 88 ibu hamil. Teknik pengambilan sampel yang digunakan adalah total sampling. Instrument penelitian menggunakan kuesioner karakteristik responden dan kuesioner kepatuhan konsumsi tablet Fe. Analisis data yang digunakan adalah uji korelasi Spearman dengan nilai = 0.05. Hasil penelitian menunjukkan nilai p value 0.535 > 0.05 pada status gizi dengan kejadian anemia pada ibu hamil dan nilai p value 0.034 < 0.05 pada kepatuhan konsumsi tablet Fe dengan kejadian anemia pada ibu hamil. Kesimpulannya tidak ada hubungan antara status gizi dengan kejadian anemia pada ibu hamil dan ada hubungan antara kepatuhan konsumsi tablet Fe dengan kejadian anemia pada ibu hamil.
Pengaruh Media Ular Tangga terhadap Tingkat Pengetahuan Anemia, Asupan Sumber Zat Besi, dan Kadar Hemoglobin Siswi Menengah Atas Falindri, Jumania; Rahmiati, Baiq Fitria; Sukanty, Ni Made Wiasty
Nutriology : Jurnal Pangan,Gizi,Kesehatan Vol 5 No 1 (2024): April 2024
Publisher : Program Studi Gizi, Universitas Bumigora

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/nutriology.v5i1.3781

Abstract

Anemia merupakan salah satu permasalahan kesehatan yang dapat dialami oleh balita, remaja, ibu hamil, dan usia lanjut. Data Riskesdas 2018 menunjukkan sebanyak 32% anemia terjadi pada usia 15-24 tahun. Remaja putri yang mengalami anemia berisiko lebih besar mengalami Kekurangan Energi Kronis (KEK) pada saat kehamilan dan berisiko melahirkan dengan Berat Badan Lahir Rendah (BBLR) dan stunting. Peningkatan asupan zat besi pada remaja putri dapat dilakukan dengan program suplementasi Tablet Tambah Darah (TTD) yang mengandung zat besi (Fe), fortifikasi makanan, dan pendidikan gizi. Pemberian pendidikan kesehatan akan memengaruhi sikap remaja putri terhadap pencegahan anemia. Penelitian ini merupakan penelitian quasi eksperimental dengan rancangan pretest-posttest with control group. Populasi penelitian ini adalah siswi SMAN 9 Mataram yang mengalami anemia dengan jumlah sampel sebanyak 62 siswi yang terbagi dalam kelompok kontrol dan kelompok intervensi. Penelitian dilakukan dengan pemberian kuisioner pengetahuan tentang anemia, kuisioner SQ-FFQ asupan sumber zat besi, dan pengecekan kadar Hb. Data hasil penelitian diolah menggunakan uji paired t-test dengan nilai α = 0,05. Hasil penelitian menunjukkan terdapat pengaruh pembelajaran dengan media permainan ular tangga terhadap pengetahuan anemia kelompok intervensi (p = 0.000), asupan sumber zat besi kelompok intervensi (p = 0.000), dan kadar hemoglobin kelompok intervensi (p = 0.000) dan kelompok kontrol (p = 0,006). Berdasarkan hasil tersebut, dapat disimpulkan bahwa terdapat pengaruh yang signifikan antara pembelajaran dengan media ular tangga terhadap pengetahun, asupan sumber zat besi, dan kadar hemoglobin siswi di SMAN 9 Mataram. Kata Kunci: Anemia, hemoglobin, ular tangga, siswi, tingkat pengetahuan.
The Effectiveness of Fragrant Pandan Leaves Ethanol Extract in Reducing Cholesterol Levels In High-Fat Diet-Induced Rats Sukanty, Ni Made Wiasty; Ariani, Farida; Yunita, Lina
Biology, Medicine, & Natural Product Chemistry Vol 13, No 2 (2024)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2024.132.505-509

Abstract

Coronary heart disease was the primary cause of death in Asia in 2019. Indonesia is the country with the highest increase in cholesterol levels in Southeast Asia. One of the causes of coronary heart disease is consuming foods high in cholesterol. The commonly given therapy is simvastatin. However, long-term use of simvastatin can cause side effects, so it is necessary to use other alternatives. Pandanus ammaryllifolius also known as fragrant pandan is a plant that is often found in Indonesia and is used in the culinary industry. This study aims to test the effectiveness of fragrant pandan leaves ethanol extract (FPLEE) in reducing cholesterol levels in rats. A total of 30 rats were split into six groups (NC, C+, C-, T1, T2, and T3) and induced on a high-fat diet, except the NC group for 14 days. For the next 14 days, C+ was given a high-fat diet, C- was given simvastatin, T1, T2, and T3 were respectively given FPLEE doses of 8, 16, and 32 mg/200 g BW/day. Next, cholesterol levels were measured. The results of cholesterol levels were tested statistically using One-Way ANOVA and post hoc LSD tests with a = 0.05. There is no substantial difference between NC, C-, and T2. There is a significant difference between T1 and C+ with a higher T1 value. Meanwhile, for T3, there is no significant difference between T3 and NC, C-, and C+. Thus, the most effective dose for reducing cholesterol levels is 16 mg/200 g BW/day.
Impact Of Fragrant Pandan Leaves Ethanol Extract (Fplee) On Alt And Ast Levels In High-Fat Diet-Induced Rat Sukanty, Ni Made Wiasty; Ariani, Farida; Yunita, Lina
Jurnal Riset Kesehatan Vol 13, No 2 (2024): NOVEMBER 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jrk.v13i2.12112

Abstract

Energy-dense, low-nutrient, and ultra-processed diets rich in fat can be a risk factor for fatty liver disease. Fragrant pandan is a plant that grows widely in Indonesia and is widely used as a herbal plant. This study aimed to determine the potential of fragrant pandan leaf ethanol extract (FPLEE) to reduce ALT and AST levels. It is a posttest control group design experiment. A total of 24 Rattus norvegicus specimens. All groups were given high-fat food for two weeks, except for NC. In the next two weeks, S was induced by simvastatin and FPLEE; T1, T2, and T3 were induced by 8, 16, and 32 mg/200 g BW/day, respectively. The One-Way ANOVA test results showed α=0.000 for ALT and α=0.029 for AST. Post-hoc LSD showed that NC was significantly different from T1, T2, and T3 (p0.05); therefore, FPLEE was unable to reduce ALT levels. For AST levels, NC was significantly different from C+, T1, and T2 (P0.05). Thus, T3 (32 mg/200 g BW/day of FPLEE) yielded the best results in reducing AST levels (p0.05). Based on these results, FPLEE has side effects on liver function, as seen in increased blood ALT levels, but it can reduce blood AST levels.
Penguatan Pola Makan Sehat sebagai Pencegahan Anemia Melalui Edukasi Isi Piringku dan Piramida Makanan di Kalangan Santri Putri Anisah, Anisah; Isasih, Widani Darma; Sukanty, Ni Made Wiasty; Fajriani, Laksmi Nur; Anggriany, Nissa
Alamtana: Jurnal Pengabdian Masyarakat UNW Mataram Vol 6 No 1 (2025): Edisi Mei 2025
Publisher : LPPM UNIVERSITAS NAHDLATUL WATHAN MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51673/jaltn.v6i1.2479

Abstract

Abstrak: Anemia merupakan salah satu masalah kesehatan yang sering ditemukan pada remaja putri khususnya di pondok pesantren dikarenakan kurangnya asupan zat besi dan pengetahuan gizi. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan gizi remaja putri di Pondok Pesantren Nurul Islam Sekarbela sebagai upaya pencegahan anemia. Edukasi diberikan kepada 8 responden usia 15–17 tahun melalui pretest, penyampaian materi tentang anemia, Piringku, dan Piramida Makanan menggunakan leaflet, food flashcard, dan food model, serta posttest. Hasil penelitian menunjukkan adanya peningkatan jumlah jawaban benar pada 13 dari 20 soal yang menunjukkan adanya peningkatan pemahaman. Analisis menggunakan uji t berpasangan dengan taraf kepercayaan 95%. Kendala teknis diatasi melalui diskusi kelompok kecil. Kegiatan ini membuktikan bahwa pendekatan edukasi dengan media interaktif efektif dalam meningkatkan pengetahuan dan kesadaran remaja akan pentingnya gizi seimbang untuk mencegah anemia.
Review: Pengaruh Produk Olahan Susu Fermentasi terhadap Risiko Penyakit Kardiovaskular: Review: The Effect of Fermented Milk Products on The Risk of Cardiovaskular Disease Fajriani, Laksmi Nur; Sukanty, Ni Made Wiasty; Anisah; Isasih, Widani Darma; Anggriany, Nissa; Najiyyah, Siti Ulfatun
Jurnal Kolaboratif Sains Vol. 8 No. 7: Juli 2025 - In Progress
Publisher : Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jks.v8i7.7892

Abstract

Penyakit Kardiovaskular (PKV) merupakan penyebab utama kematian global yang diperkirakan akan terus meningkat hingga tahun 2050. Faktor risiko utama PKV meliputi hipertensi, dislipidemia, hiperkolesterolemia, dan hiperglikemia. Salah satu strategi pencegahan yang mendapat perhatian adalah konsumsi produk olahan susu fermentasi seperti yoghurt, kefir, dan keju yang mengandung probiotik dan senyawa bioaktif hasil fermentasi. Probiotik seperti Lactobacillus dan Bifidobacterium berperan dalam menurunkan kadar kolesterol total, LDL, serta meningkatkan HDL melalui berbagai mekanisme termasuk penghambatan enzim HMG-CoA reduktase dan peningkatan ekskresi asam empedu. Selain itu, produk susu fermentasi diketahui berkontribusi dalam menurunkan tekanan darah, meningkatkan kesehatan usus, serta mengurangi peradangan sistemik yang berperan dalam patogenesis aterosklerosis. Studi epidemiologis menunjukkan hubungan signifikan antara konsumsi tinggi produk susu fermentasi dengan penurunan risiko PKV, hipertensi, dan stroke. Metode penyusunan yang digunakan adalah kajian literatur metode PRISMA dengan pendekatan deskriptif menggunakan pustaka sekunder melalui empat langkah yaitu identification, screening, eligibility, dan included sehingga didapatkan 14 artikel. Hasilnya menunjukkan bahwa produk olahan susu fermentasi mengandung bakteri probiotik dan senyawa bioaktif yang berperan dalam menurunkan LDL, meningkatkan HDL, sehingga mampu menurunkan risiko PKV. Penelitian ini mengimplikasikan bahwa mengkonsumsi produk olahan susu fermentasi (yoghurt, keju, susu fermentasi) dalam jumlah tinggi dapat menurunkan risiko PKV sebesar 19% dibandingkan dengan konsumsi rendah.
Co-Authors Anggriany, Nissa ANISAH Anisah Ardian, Junendri Astawan, Wanda Januar DarmaIsasih, Widani Defel Septian Dewi, Novianti Tysmala Dewi, Novianty Tysmala Falindri, Jumania Farida Ariani I Putu Bayu Agus Saputra Jauhari, M. Thonthowi Laksmi Nur Fajriani Naktiany, Wayan Canny Novia Zuriatun Solehah Rahmiati, Baiq Fitria Santika, I Gede Panji Siti Ulfatun Najiyyah, Siti Ulfatun Utami, Syintia Widani Darma Isasih Yunita, Lina