Article Per Year (5 Year)
p-Index From 2021 - 2026
3.298
P-Index
This Author published in this journals
All Journal Jurnal Riset Kesehatan Biology, Medicine, & Natural Product Chemistry GANEC SWARA Bioscientist : Jurnal Ilmiah Biologi Nutriology: Jurnal Pangan, Gizi, Kesehatan ADMA: Jurnal Pengabdian dan Pemberdayaan Masyarakat Jurnal Kolaboratif Sains JAPI: Jurnal Akses Pengabdian Indonesia Bakti Sekawan : Jurnal Pengabdian Masyarakat Alamtana
Sukanty, Ni Made Wiasty
Unknown Affiliation
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

Published : 23 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 23 Documents
Search

 1   2   3 
Beneficial Effect of Sumbawa Wild Horse Milk Yogurt on Lipid Profile and Cardiovascular Risk in Rats on a High-Cholesterol Diet Fajriani, Laksmi Nur; Sukanty, Ni Made Wiasty; Putri, Dea Pratiwi Silpia; Febriani, Esya Mariska
Biology, Medicine, & Natural Product Chemistry Vol 14, No 2 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.142.1129-1135

Abstract

Cardiovascular disease (CVD) is a leading cause of death in Indonesia, with a high prevalence due to a high-cholesterol diet that triggers hypercholesterolemia. The use of statins as a long-term pharmacological therapy often causes side effects, so safe natural alternatives are needed. Sumbawa wild horse milk is a potential functional food source that contains essential fatty acids and lactic acid bacteria (LAB), which have probiotic potential. This study aims to evaluate the effect of Sumbawa wild horse milk yogurt on total cholesterol, HDL, LDL, Atherogenic Index (AI), and Cardiac Risk Ratio (CRR) levels in hypercholesterolemic male Wistar rats. A total of 30 rats were divided into six groups: normal, positive control (high-cholesterol diet), negative control (simvastatin), and three treatment groups, T1, T2, and T3, with doses of Sumbawa wild horse milk yogurt of 2, 3, and 4 ml/day, respectively, for 28 days. The results showed a significant decrease in total cholesterol levels (p = 0.006), with the lowest levels observed in the T3 treatment group (95.25 ± 20.17 mg/dL). Although HDL, LDL, IA, and CRR levels did not show significant differences (p > 0.05), a trend of improvement in lipid profiles was observed in the treatment group, characterized by an increase in HDL and a decrease in LDL, AI, and CRR compared to the positive control. The mechanism of cholesterol reduction is thought to be mediated through the activity of LAB, which assimilates cholesterol, facilitates bile acid deconjugation, and produces short-chain fatty acids that inhibit cholesterol absorption. Thus, Sumbawa wild horse milk yogurt has the potential to be a hypocholesterolemic functional food that can improve lipid profiles and reduce the risk of atherosclerosis and CVD.
Fragrant Pandan (Pandanus ammaryllifolius) Leaves Ethanol Extract as an Enhancer of Endogenous Antioxidant Defence under High-Fat Diet Conditions Sukanty, Ni Made Wiasty; Fajriani, Laksmi Nur; Saputra, I Putu Bayu Agus; Ariki, Iptan; Aditya, I Ketut Agus Yura
Biology, Medicine, & Natural Product Chemistry Vol 14, No 2 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.142.1171-1176

Abstract

Excessive fat consumption, especially saturated and trans fatty acids, plays a significant role in metabolic disorders such as obesity, dyslipidemia, and cardiovascular disease through increased oxidative stress. Malondialdehyde (MDA), the end product of lipid peroxidation, serves as a biomarker of oxidative damage, whereas indirect bilirubin acts as an endogenous antioxidant. This study aimed to evaluate the effect of fragrant pandan leaves ethanol extract (FPLEE) in reducing MDA levels and modulating indirect bilirubin activity in rats fed a high-fat diet (HFD). The experimental method used 24 male Rattus norvegicus divided into six treatment groups: normal control (NC), positive control (C+), negative control (C-), and three FPLEE treatment groups with different doses (8, 16, and 32 mg/200 g BW/day). Administration was carried out for 14 days after 14 days of HFD induction. MDA levels were measured using the ELISA method, while total bilirubin and direct bilirubin were measured using spectrophotometry to determine indirect bilirubin levels. Statistical analysis was performed using one-way ANOVA and the post hoc Bonferroni test. The results showed that there were no significant differences in MDA levels between groups, although the C+ group fed a HFD showed a tendency toward increased MDA. Indirect bilirubin levels increased significantly in the low-dose FPLEE group (8 mg/200 g BW/day), indicating increased endogenous antioxidant activity, while higher doses did not. Thus, FPLEE has the potential to be an effective natural phytopharmaceutical agent in enhancing the body's antioxidant defence against oxidative stress caused by excessive fat consumption, especially at low doses.
Kesehatan Fisik dan Mental Remaja: Hubungan Status Gizi dan Tingkat Stres Di Sekolah Menengah Kejuruan Anggriany, Nissa; Fajriani, Laksmi Nur; Sukanty, Ni Made Wiasty; Anisah, Anisah; Isasih, Widani Darma; Ardian, Junendri; Saputra, I Putu Bayu Agus
Bakti Sekawan : Jurnal Pengabdian Masyarakat Vol. 6 No. 1 (2026): Juni
Publisher : Puslitbang Sekawan Institute Nusa Tenggara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35746/bakwan.v6i1.931

Abstract

Adolescents are an age group vulnerable to various health problems, both physical and mental, along with the biological and psychosocial changes that occur during their developmental phase. Nutritional status and stress levels are two important aspects that play a role in determining adolescent well-being, however existing evidence regarding the relationship between these two variables remains inconsistent. This community service activity aims to describe the nutritional status and stress levels of adolescents and analyze the relationship between nutritional status and stress levels in adolescents in the school environment. The activity was carried out at SMKN 2 Lembar involving 21 adolescents aged 15–17 years using an observational analytical approach with a cross-sectional design. Data collection was carried out by filling out questionnaires on respondent characteristics and stress levels, as well as anthropometric measurements to determine nutritional status. Data were analyzed univariately and bivariately using the Fisher Exact test as an alternative. The results showed that most respondents were 16 years old (42.8%), had good nutritional status (90.5%), and experienced moderate stress (90.5%). The results of the bivariate analysis showed no significant relationship between nutritional status and stress levels in adolescents (p = 0.890). The conclusions of this activity indicate that stress levels in adolescents are not directly related to nutritional status but are likely more influenced by psychosocial factors. Therefore, community service programs in schools need to be implemented holistically, integrating nutrition education and mental health promotion to improve adolescent well-being.
Co-Authors Aditya, I Ketut Agus Yura Anggriany, Nissa ANISAH Anisah Anwariah, Jukhairiatun Ariki, Iptan Astawan, Wanda Januar Azani, Anggun Sukma DarmaIsasih, Widani Defel Septian Dewi, Novianti Tysmala Dewi, Novianty Tysmala Erna Sari, Erna Falindri, Jumania Farida Ariani Febriani, Esya Mariska I Putu Bayu Agus Saputra Jauhari, M. Thonthowi Laksmi Nur Fajriani Naktiany, Wayan Canny Novia Zuriatun Solehah Putri, Baiq Amelia Eka Helvyana Putri, Dea Pratiwi Silpia Rahmiati, Baiq Fitria Santika, I Gede Panji Siti Ulfatun Najiyyah, Siti Ulfatun Utami, Syintia Widani Darma Isasih Yunita, Lina