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Indonesia Black Cumin (Nigella sativa L.) Seeds Extract as Ameliorant Reproductive Function in Type-2 Diabetes Mellitus Retno Susilowati; Nailirrohmah Hidayatin; Amalia Rizka Diana; Tri Kustono Adi
Biogenesis: Jurnal Ilmiah Biologi Vol 8 No 1 (2020)
Publisher : Department of Biology, Faculty of Sci and Tech, Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/bio.v8i1.11973

Abstract

Diabetes initiates augmented damage in levels of nuclear and mitochondrial DNA in males. As a result, the sperm DNA is affected, as well, leading to lower levels of fecundity and influencing reproductive health. This study aims to improve male reproductive function and oxidative stress status in diabetic rats. Combination High Fat Diet (HFD) and Streptozotocin (STZ) injection 30 mg/kg intraperitoneally are the initiations of DM-2 for 14 weeks. Treat therapy using 80% ethanol extract of black cumin seeds takes five weeks. Based on parametric test on ANOVA test results followed by Duncan Multiple Range Tests on the concentration, abnormalities of spermatozoa and Super Oxide Dismutase (SOD) effects and the Kruskal-Wallis test followed by the Mann-Whitney test on non-parametric data of the spermatozoa motility and Malondialdehyde (MDA) levels, showed that obtaining black cumin dose 48 is an effective dose in improving sperm quality and stress oxidation level. It has the same effect with metformin, even has MDA level less than normal rats. This study finds out Ns-48 is an effective dose of ethanol extract of black cumin seeds to improving spermatozoa quality and stress oxidation level, so that it becomes valuable information for research related to the improvement of reproductive function in diabetes mellitus disease.
Sintesis dan Pemanfaatan Kitosan Berbasis Limbah Udang: Integrasi Etika Islam dan Sains dalam Pengembangan Bahan Ramah Lingkungan Choiriyah, Ainur Rizqi; Madjid, Armeida D.R; Yulianti, Eny; Mubasyiroh, Mubasyiroh; Adi, Tri Kustono; Zulfikar, M. Ali; Setiyanto, Henry
Es-Syajar:Journal of Islam, Science and Technology Integration Vol 3, No 1 (2025): Es-Syajar:Journal of Islam, Science and Technology Integration
Publisher : UNIVERSITAS ISLAM NEGERI MAULANA MALIK IBRAHIM MALANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/es.v3i1.34468

Abstract

The increasing shrimp production and consumption in Indonesia generates significant amounts of shrimp shell waste, which has not been optimally utilized and often becomes an environmental problem. This waste is rich in chitin, which can be processed into chitosan—a multifunctional biopolymer with various applications in food, health, agriculture, and environmental fields. This literature review explores the synthesis process, characterization, and utilization of chitosan derived from shrimp shell waste, while highlighting the importance of integrating Islamic ethical values in the sustainable management of natural resources. The synthesis of chitosan involves demineralization, deproteinization, and deacetylation steps, with critical parameters such as temperature, time, and base concentration affecting the degree of deacetylation. The review shows that utilizing shrimp shell waste as a source of chitosan not only supports circular economy principles and waste reduction but also aligns with Islamic teachings on responsible environmental stewardship. The integration of science and Islamic ethics is expected to promote the development of high-value, sustainable, and environmentally friendly biomaterials.
Synthesis of Bi4Ti3O12/Alga for Ciprofloxacin Degradation Prasetyo, Anton; Adi, Tri Kustono; Kartika, Siska Ela; Faturrohmi, Fauziah; Khanif, Juwita
al Kimiya: Jurnal Ilmu Kimia dan Terapan Vol. 12 No. 1 (2025): June 2025
Publisher : Department of Chemistry, Faculty of Science and Technology, UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/ak.v12i1.42256

Abstract

Antibiotic waste has become a serious issue for ecosystems, and one method that offers great potential to address this problem is photocatalysis. To enhance the photocatalytic activity, one approach is to impregnate the photocatalytic compound onto a supporting material and become composite material. In this study, Bi4Ti3O12/Algae (Spinossum cottonii, Euchema spinossum, and Sargassum sp) composite compounds were synthesized with various algae, including Sargassum and Spinosa. The diffractogram and IR spectra data indicate that the composite compounds were successfully synthesized. The photocatalytic activity test results demonstrate good potential for the Bi4Ti3O12/Euchema spinossum composite in the degradation of ciprofloxacin, as it was able to degrade 30% of ciprofloxacin within 60 minutes.