Article Per Year (5 Year)
p-Index From 2021 - 2026
3.725
P-Index
This Author published in this journals
All Journal Pharmaciana: Jurnal Kefarmasian JPSCR : Journal of Pharmaceutical Science and Clinical Research Jurnal Riset Kefarmasian Indonesia Jurnal Ilmiah Medicamento Jurnal Pengabdian Masyarakat Asia Jurnal Pengabdian kepada Masyarakat Pharmaceutical And Biomedical Sciences Journal (PBSJ) Usadha Journal of Pharmacy Borneo Journal of Pharmacy
Nyoman Budiartha Siada
Universitas Mahasaraswati Denpasar
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

Published : 20 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 20 Documents
Search

 1   2 
SOSIALISASI CEK KLIK (KEMASAN, LABEL, IZIN EDAR, KADALUARSA) UNTUK MENDUKUNG PENGGUNAAN OBAT DENGAN AMAN DAN CERMAT DI ERA NEW NORMAL PANDEMI COVID-19 Ni Made Dharma Shantini Suena; Debby Juliadi; I Gede Made Suradnyana; Rr. Asih Juanita; Nyoman Budiartha Siada; Ni Putu Udayana Antari
J-ABDI: Jurnal Pengabdian kepada Masyarakat Vol. 1 No. 11: April 2022
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53625/jabdi.v1i11.1853

Abstract

Masyarakat dapat mengetahui keamanan dan mutu obat, serta kesesuaiannya dengan keluhan yang diderita, dengan cara mencermati dengan baik informasi obat sebelum digunakan. Cek KLIK merupakan Slogan yang dicetuskan oleh BPOM yang merupakan singkatan dari Cek Kemasan, Label, Izin Edar, Kadaluarsa, dari obat maupun olahan pangan yang akan dikonsumsi. Namun sebagian masyarakat belum mengetahui dengan baik langkah-langkah Cek KLIK maupun pentingnya melakukan hal ini demi menjamin penggunaan obat dengan tepat dan aman. Pandemi COVID-19 menyebabkan terjadinya peningkatan konsumsi sediaan farmasi khususnya suplemen kesehatan demi menjaga imunitas dalam menghadapi pandemi. New Normal adalah kebijakan membuka kembali aktifitas ekonomi sosial dan kegiatan publik secara terbatas dengan menggunakan standar kesehatan yang sebelumnya tidak ada sebelum pandemi. New normal diberlakukan di Indonesia sejak awal Juni 2020. Untuk meningkatkan pengetahuan masyarakat tentang penggunaan obat yang aman, cermat, dan bermutu di masa new normal pandemi COVID-19, dilakukan kegiatan pengabdian masyarakat berupa sosialisasi Cek KLIK sediaan obat.
Antibiotic consumption and resistance: a 3-years ecological study for four critical groups of bacteria in a general regional hospital Dwi Arymbhi Sanjaya; Nyoman Budiartha Siada; Rr Asih Juanita; I Putu Yudistira Mahaputra; Made Gek Adisti Kamalia; Herleeyana Meriyani
Pharmaciana Vol 14, No 1 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i1.27321

Abstract

Pseudomonas aeruginosa, Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae are the most critical groups of multi-drug resistant (MDR) bacteria that cause a threat in hospitals. This study identified the trend of antibiotic consumption, antibiotic resistance pattern, and the relationship between antibiotic consumption and antibiotic resistance in a critical group of bacteria in a general regional hospital. This ecological study was based on retrospective data from inpatient databases in a general regional hospital over three years (2017-2019). The trend for annual antibiotic consumption over 2017-2019 was defined as defined daily doses/100 bed-days. The relationship between total antibiotic consumption and the percentage of antibiotic resistance among four isolated critical bacteria was explored in time series analysis and linear regression. The most frequently used antibiotic was ampicillin (220.33 DDD/100 bed-days), ciprofloxacin (126.86 DDD/100 bed-days), and ampicillin-sulbactam (126.34 DDD/100 bed-days). There was a significant relationship between antibiotic consumption (ampicillin, ampicillin-sulbactam, ceftazidime, gentamicin, amikacin, and ciprofloxacin) in DDD/100 bed-days and antibiotic resistance in E. coli, K. pneumoniae, and P. aeruginosa (p<0.05) but not statically significant in A. baumannii (p=0.062). The annual usage fluctuated or remained stable, with no statistically significant trends change. The relationship between antibiotic consumption and antibiotic resistance was significant in three out of four critical groups of bacteria.
Cultivation and Analysis of Citronella Essential Oil Compounds for Traditional Medicine Development Dewa Ayu Ika Pramitha; Agung Ari Chandra Wibawa; Nyoman Budiartha Siada; Gde Nyoman Astika; Ni Made Sukma Sanjiwani
Jurnal Pengabdian Masyarakat Vol 4 No 2 (2023): Jurnal Pengabdian Masyarakat
Publisher : Institut Teknologi dan Bisnis Asia Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32815/jpm.v4i2.1234

Abstract

Purpose: This study addresses challenges faced by Mahapraja, a Bali tourist cottage. It explores issues related to citronella cultivation, trust-building, limited land, equipment underutilization, and marketing hurdles. It is relevant for regional traditional medicine and agriculture. Method: This research uses a mixed-method approach, combining qualitative data collection (interviews, surveys, observations) with quantitative analysis (Gas Chromatography-Mass Spectrophotometer). Pre- and post-tests gauge knowledge enhancement during socialization activities. Practical Applications: The findings improve citronella cultivation in Mahapraja, boosting essential oil production and benefiting the cottage and traditional medicine industry. It informs marketing strategies, instilling confidence in producing and selling derivative products. Conclusion: This study highlights Mahapraja's citronella challenges, setting the stage for agricultural improvements and effective marketing. It underscores research's role in advancing regional traditional medicine and agriculture, positioning Mahapraja for success in citronella essential oil production and sales.
POLA PERESEPAN OBAT ANTIHIPERTENSI DI POLI RAWAT JALAN RUMAH SAKIT “X” DI BALI PERIODE TAHUN 2022 Ni Nyoman Yudianti Mendra; I Gusti Ayu Puspasari; Nyoman Budiartha Siada
Usadha Journal of Pharmacy Vol. 3 No. 2 (2024): Mei
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/ujp.v3i2.311

Abstract

Hipertensi merupakan salah satu penyakit kronis dengan tingkat kejadian yang tinggi dan beresiko menyebabkan komplikasi. Pengobatan dan peresepan obat yang rasional diperlukan untuk mengontrol tekanan darah pasien serta mencegah terjadinya komplikasi. Penelitian ini bertujuan untuk mengetahui pola peresepan dan rasionalitas terapi antihipertensi pada pasien rawat jalan di salah satu rumah sakit umum di Bali tahun 2022 dengan BPJS sebagai jaminan asuransi kesehatan. Penelitian ini merupakan penelitian deskriptif dengan pengambilan data secara retrospektif dimana teknik pengambilan sampelnya menggunakan purposive sampling. Kriteria inklusi dalam penelitian ini meliputi pasien hipertensi dengan dan tanpa komorbid, telah menjalani pengobatan minimal 3 bulan terapi pada periode Januari - Desember 2022. Rasionalitas terapi meliputi tepat obat, tepat pasien, tepat dosis, dan tepat interval waktu pemberian yang dinilai berdasarkan pedoman JNC 8 dan Konsensus Penatalaksanaan Hipertensi Tahun 2021. Berdasarkan data dari 368 pasien rawat jalan, antihipertensi yang diresepkan meliputi Angiotensin receptor blocker (ARB) dengan persentase 64,13%; Calsium Channel Blocker (CCB) 59,51%; Angiotensin Converting Enzim Inhibitor (ACEI) 16,85%; Beta Blocker 15,22% dan diuretik sebesar 0,81%. Pada hasil evaluasi peresepan obat antihipertensi diperoleh tepat obat sebanyak 98,64%, tepat pasien sebanyak 96,74%, tepat dosis sebanyak 100%, dan tepat interval waktu pemberian sebanyak 100%.
Kualitas Penggunaan Antibiotik pada Pasien Community-Acquired Pneumonia di Salah Satu Rumah Sakit di Bali Meriyani, Herleeyana; Sanjaya, Dwi Arymbhi; Juanita, Rr. Asih; Siada, Nyoman Budiartha
Jurnal Ilmiah Medicamento Vol 10 No 1 (2024): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v10i1.7592

Abstract

Community-acquired pneumonia (CAP) is an infectious disease with high morbidity and mortality rates. Antibiotics are essential therapies for bacterial CAP. The use of antibiotics is a critical point in CAP treatment. Inappropriate use of antibiotics leads to antibiotic resistance. The study aimed to evaluate the proper use of antibiotics in CAP patients and identify the relationship between the appropriate use of antibiotics and the use of single/combined antibiotics with prolonged length of stay. This study was a cross-sectional study with retrospective data collection at a general hospital in Bali. Evaluation of the proper use of antibiotics was done using the Gyssens algorithm. The relationship between the appropriate use of antibiotics and the type of antibiotic (single/combined) with the length of stay was carried out using the Chi-square test with a 95% confidence interval. There were 151 CAP patients as samples in this study consisting of 55.63% men and 44.37% women with a median age of 60 years (18-89). The appropriate use of antibiotics was 17.88%, while 82.18% of the total antibiotic use was inappropriate. The Inappropriate use of antibiotics in category IIA (incorrect dosage) is 3.97%, category IIIB (inappropriate interval) is 4.64%, category IVC (cheaper alternative antibiotics were available) is 41.72%, and category V (no indication) is 37.79%. There is no significant relationship between the appropriate use of antibiotics and prolonged LOS [p>0.05; OR: 1.132 (CI: 0.466-2.746)] however the use of antibiotics (single or in combination) significantly affects the prolonged LOS [p<0.05; OR: 0.027 (CI: 0.004-0.204)].
Studi Retrospektif Penggunaan Antibiotik pada Pasien Covid-19 dengan Pneumonia di Rumah Sakit “X” Provinsi Bali, Indonesia Siada, Nyoman Budiartha; Juanita, Rr Asih; Sanjaya, Dwi Arymbhi; Meriyani, Herleeyana
Jurnal Ilmiah Medicamento Vol 10 No 1 (2024): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v10i1.7637

Abstract

COVID-19 with bacterial pneumonia co-infection is a condition with bacteria present in COVID-19 patients. The prevalence of bacterial co-infection in COVID-19 patients ranges from 12.4%–50%. This study aims to determine the relationship between the appropriate use of antibiotics and the severity of inpatients with COVID-19 and pneumonia co-infection at Hospital "X" Bali Province, Indonesia. This research is an observational study with a cross-sectional approach. Data collection was carried out retrospectively on medical record data of COVID-19 inpatients with pneumonia co-infection at Hospital "X" Bali Province, Indonesia for the period January - December 2021. The sampling technique used total sampling according to inclusion and exclusion criteria. Appropriate use of antibiotics antibiotic was analyzed using Pharmaceutical Care Network Europe (PCNE) version 9.1. The patient severity index was an assessment based on the Pneumonia Severity Index (PSI) score. The relationship between the appropriate use of antibiotics and the severity of inpatients with COVID-19 and pneumonia co-infection was analyzed using Fisher's test. Of the 80 COVID-19 inpatients with pneumonia co-infection, 90% experienced inappropriate use of antibiotics. Fisher's test results showed that there was no significant relationship between the appropriate use of antibiotics and the severity of inpatients with COVID-19 and pneumonia co-infection at Hospital "X" Bali Province, Indonesia (p > 0.05).
Eribulin Effectiveness and Safety in Metastatic Triple-Negative Breast Cancer: A Narrative Review Meriyani, Herleeyana; Sanjaya, Dwi Arymbhi; Juanita, Rr. Asih; Siada, Nyoman Budiartha; Chusna, Nurul; Ketupapa, Florentina Gabriela
Borneo Journal of Pharmacy Vol. 8 No. 1 (2025): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v8i1.7913

Abstract

Triple-negative breast cancer is an aggressive and poor prognosis subtype of breast cancer. Eribulin has shown promise in the treatment of metastatic triple-negative breast cancer (mTNBC). This review aimed to provide a specific description, evidence, and discussion of the efficacy and safety of eribulin both as monotherapy and in combination with another agent in patients with mTNBC. The search was conducted in five databases (PubMed, ScienceDirect, PLoS One, Wiley Online Library, and Cochrane Library) towards published articles during the 2013-2023 period. A total of 237 articles were identified. After removing 69 duplicates, 168 articles underwent the screening process and 10 articles met the research criteria. Eribulin monotherapy effectiveness profile includes: overall survival (10.8-17.6 months), progression-free survival (2.8-3.2 months), partial response (21.0%-58.7%), progressive disease (15.5% -47.0%), and stable disease (28.8%-32%). However, there were no cases of complete response. Combination of eribulin with other agents' effectiveness profiles includes: overall survival (8.3-14.5 months), PFS (2.6-8.1 months), partial response (31.8-76.0%), complete response (2.4-8%), progressive disease (8.0-28%), and stable disease (8.0-52.3%). Eribulin monotherapy's safety profile is similar to that of combination therapy. No grade 5 adverse event was reported during monotherapy or in combination with other agents. The grade 4 adverse events reported are neutropenia, leukopenia, thrombocytopenia, anemia, peripheral neuropathy, fatigue, diarrhea, vomiting, dyspnea, back pain, arthralgia, febrile neutropenia, dyspnea, constipation, general physical health deterioration, alopecia. The all-grade adverse events with a percentage above 50% are neutropenia, leukopenia, thrombocytopenia, asthenia, alopecia, elevated AST, elevated ALT, hand-foot syndrome, fatigue, anemia, peripheral neuropathy, oral mucositis, and nausea.
Cross-resistance to antibiotics of Escherichia coli in the inpatient installation of general regional hospital “X” Bali, Indonesia Mahaputra, I Putu Yudistira; Sanjaya, Dwi Arymbhi; Meriyani, Herleeyana; Juanita, Rr Asih; Siada, Nyoman Budiartha; Kamalia, Made Gek Adisti; Adrianta, Ketut Agus; Noviani, Lusy
Pharmaciana Vol. 15 No. 1 (2025): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v15i1.29209

Abstract

Escherichia coli (E. coli) is a critical-priority group of MDR bacteria and its spread can occur in hospital inpatient settings. Several studies showed that antibiotics consumption for inpatients can cause E. coli resistance to other antibiotics called cross-resistance. The aim of this study to determine the cross-resistance in E. coli to antibiotics in the inpatient installation of the regional general hospital "X" in Bali, Indonesia by analyzing the relationship between the antibiotic consumption and the percentage of antibiotic resistance of E. coli. This research is an ecological study with the independent variable is the antibiotics consumption defined as defined daily doses/100 bed-days and the dependent variable is the percentage of E. coli resistance during 2017-2020. The correlation between the level of antibiotic consumption and the percentage of E. coli resistance to antibiotics was analyzed using the Pearson correlation tests. The results showed that the consumption of tetracycline had a significant correlation with increased resistance of E. coli to meropenem and piperacillin-tazobactam (r=0.8-1.0; p<0.05). This showed that there is cross-resistance in E. coli. This incident is associated with selective pressure, horizontal and vertical gene transfer in E. coli. The consumption of tetracycline, apart from inducing the production of the tet gene which is the cause of resistance to tetracycline, can also induce the production of resistance genes to broad-spectrum beta-lactam antibiotics such as piperacillin-tazobactam and meropenem.
Efektivitas dan Efek Samping pada Terapi Multi-Drug-Resistant Tuberculosis (MDR-TB): Kajian Literatur Sanjaya, Dwi Arymbhi; Meriyani, Herleeyana; Juanita, Rr. Asih; Siada, Nyoman Budiartha; Noviani, Lusy
Jurnal Ilmiah Medicamento Vol 11 No 1 (2025): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v11i1.9685

Abstract

Multi-drug-resistant tuberculosis (MDR-TB) leads to a reduced cure rate for tuberculosis treatment. The global number of MDR-TB cases remained relatively stable between 2015 and 2020 but increased in 2021. In 2020, the World Health Organization (WHO) estimated 437,000 MDR-TB cases worldwide, which rose to 450,000 cases in 2021. Various treatment regimens recommended by the WHO require a review of the literature on the efficacy and side effects of drug use in MDR-TB. This review aims to provide updated information that can be used as a reference for the early identification and management of side effects. The article was a narrative review that collected and analyzed information from various international articles on databases such as PubMed, PlosOne, and ScienceDirect from January 2014 to June 2024. A total of six relevant articles were synthesized from 609 articles. The effectiveness of MDR-TB therapy with WHO-recommended drugs has shown a high cure rate (cured>50%). The incidence of side effects in MDR-TB therapy is smaller compared to the effectiveness of treatment. However, a study conducted at Wuhan Jinyintan Hospital in China from July 2019 to December 2020 showed that all study subjects experienced side effects. This included nausea and vomiting from protionamide, gatifloxacin, and ethambutol; hyperuricemia from pyrazinamide, and hyperpigmentation from clofazimine. It is recommended that a therapy regimen be selected based on culture test results, patient conditions, and drug availability in each country.
Faktor-Faktor yang Mempengaruhi Lama Rawat Inap Pasien Dengue Hemorrhagic Fever di Salah Satu Rumah Sakit Umum Daerah di Bali Siada, Nyoman Budiartha; Juanita, Rr Asih
Jurnal Ilmiah Medicamento Vol 11 No 1 (2025): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v11i1.9852

Abstract

The World Health Organization (WHO) reported one to five million dengue infections from 2020 to 2022. According to Indonesian Health Profile data in 2020, the province of Bali had the highest Dengue Hemorrhagic Fever (DHF) Incidence Rate (IR), 273.1 morbidity, and a Case Fatality Rate (CFR) of 0.2%. The longer the patient's stay, the greater the costs are incurred for hospital treatment. Therefore, this study aims to analyze the factors influencing the length of stay of DHF patients with complications and comorbidities. This study was an observational study. Medical record data of DHF patients with complications and comorbidities were collected using a retrospective technique from January 2020 to December 2020 during hospitalization at a regional public hospital in Bali. The independent variables in this study include age, the severity of DHF, complications and comorbidities, and the amount of fluid therapy patients use during hospitalization. The dependent variable in this study is the patient's length of stay. The relationship between the independent and dependent variables was analyzed using logistic regression with a significance level set at p<0.05. There were 115 hospitalized DHF patients with complications and comorbidities, consisting of 52% males and 48% females. Most patients were in the age range of 6-11 years (43%). Based on the analysis that has been carried out, there is a factor that is significantly related to the length of stay of DHF patients, namely the use of the amount of fluid therapy (p=0.02). The findings of this study support the evaluation of DHF therapy, particularly in selecting the type and volume of fluids.
Co-Authors Agung Ari Chandra Wibawa Ambara Damayanti, Made Elvenia Chusna, Nurul Debby Juliadi Dewa Ayu Ika Pramitha Dwi Arymbhi Sanjaya Gde Nyoman Astika Herleeyana Meriyani I Gede Made Suradnyana I Gusti Ayu Puspasari I Komang Gede Mahardika I Putu Yudistira Mahaputra Kamalia, Made Gek Adisti Ketupapa, Florentina Gabriela Ketut Agus Adrianta Made Gek Adisti Kamalia Mahaputra, I Putu Yudistira Mahaputra, Yudistira Mahardika, I Komang Gede Marwati, I Gusti Ayu Mendra, Ni Nyoman Yudianti Meriyani, Herleeyana Ni Made Dharma Shantini Suena Ni Made Sukma Sanjiwani Ni Nyoman Yudianti Mendra Ni Putu Udayana Antari Noviani, Lusy Prascitasari, Nyoman Ayu Puspasari, I Gusti Ayu Putu Sukma Purnamasari RR. Asih Juanita Suradnyana, I Gede Made Suryawan, Kadek Triska Ananda Rahayu Wulandari, Ni Putu Nadya Kirana Yudiartha, I Wayan Maysa