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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Cermin Dunia Kedokteran Media Dermato-Venereologica Indonesiana
Rahma, Alfina
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Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Terapi Kortikosteroid Sistemik untuk Sindrom Steven Johnson (SSJ)- Nekrolisis Epidermal Toksik (NET) di RSUD DR Moewardi, Surakarta, Indonesia Novi Diana, Eka Devinta; Tri Irfanti, Rakhma; Rahma, Alfina; -, Frieda; Nugraha, Wibisono; Eko Irawanto, Muhammad
Cermin Dunia Kedokteran Vol 48, No 4 (2021): Dermatologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1195.538 KB) | DOI: 10.55175/cdk.v48i4.1363

Abstract

Latar belakang :Sindrom Steven Johnson (SSJ) dan nekrolisis epidermal toksik (NET) adalah manifestasi reaksi alergi obat paling berat dan mengancam jiwa yang dimediasi sel T. Salah satu terapi SSJ-NET yaitu kortikosteroid sistemik. Tujuan : Mengetahui pola terapi kortikosteroid sistemik di Instalasi Rawat Inap RSUD Dr. Moewardi Surakarta periode Januari 2014-Desember 2018. Metode : Penelitian deskriptif retrospektif atas data rekam medis pasien SJS-NET di Instalasi Rawat Inap RSUD Dr. Moewardi Surakarta periode Januari 2014-Desember 2018. Hasil : Didapatkan 80 pasien SJS-NET, usia terbanyak 46-65 tahun (39%), lebih banyak laki-laki (52%). Diagnosis SSJ paling banyak (61%) dibandingkan SSJ overlap NET (24%) maupun NET (15%) dengan keterlibatan mukosa mulut terbanyak (64%). Penyakit penyerta terbanyak adalah diabetes melitus (18 %). Penyebab SSJ-NET terbanyak diduga lebih dari satu obat (44%). Terapi kortikosteroid sistemik berupa injeksi metilprednisolon dengan rata-rata dosis 65 mg/hari dan lama perawatan 10 hari. Simpulan :Kortikosteroid sistemik merupakan terapi semua kasus SSJ-NET di RSUD dr. Moewardi Surakarta.Background: Steven Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are the severest primarily T-cell mediated manifestation and life threatening drug reaction. Systemic corticosteroid is used for SJS-TEN management. Objective: To study the pattern of systemic corticosteroid therapy for SJS-TEN in Dr.Moewardi General Hospital Surakarta Januari 2014-December 2018. Method: A descriptive retrospective study on medical record data of SJS-TEN patients hospitalized at Dr.Moewardi General Hospital Surakarta between January 2014 and December 2018. Results: From a total 80 SJS–TEN patients in this study, 39% was 46-65 year-old, male (52%). The most frequent diagnosis was SJS (61%) followed by SJS overlap TEN (24%) and TEN (15%), mostly with mucosal mouth involvement (64%). The most frequent comorbidities was DM (18%). More than one drug were related to SJS-TEN (44%). Therapy for all cases was systemic corticosteroids with an average dose of methylprednisolone 65 mg per day in 10 days. Conclusion :Systemic corticosteroids was used in all cases of SSJ-NET in Dr.Moewardi General Hospital Surakarta.  
Hand Eczema in Nurses in COVID-19 Treatment Room: Frequency of Handwashing, Hand Sanitizer, Moisturizer, and Duration of Latex Gloves Use Rosmarwati, Ervina; Widhiati, Suci; Novriana, Dita Eka; Rahma, Alfina; Kariosentono, Harijono; Irawanto, Muhammad Eko; Kusumawardani, Arie; Ellistasari, Endra Yustin; Oktavriana, Triasari
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 2 (2022): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.2.2022.92-98

Abstract

Background: The COVID-19 pandemic causes health workers to use level 2 and level 3 personal protective equipment. Hand washing and the use of latex gloves are important in limiting the spread of COVID-19, but they can potentially induce hand eczema and skin pH disturbance if used too frequently. Purpose: Determine the correlation between the frequency of handwashing and duration of using hand sanitizer and moisturizer as well as skin pH level on the incidence of hand eczema in nurses in the COVID-19 treatment room at RSUD Dr. Moewardi Surakarta. Methods: This cross-sectional study was conducted in the COVID-19 treatment room at RSUD Dr. Moewardi Surakarta with 90 nurses as subjects. A validated questionnaire carried out the frequency of handwashing, hand sanitizer, moisturizer, duration of using latex gloves, and hand eczema complaints. The subject's pH assessment was conducted after 4-5 hours in the COVID-19 treatment room. Data were analyzed bivariately with a Spearman rank correlation test. Result: There was a significant correlation with the incidence of hand eczema with the frequency of handwashing with soap (r=0.305 and p=0.003) and the duration of using latex gloves (r=0.328 and p=0.002) with a weak category correlation (r=0.200-0.399). The frequency of using hand sanitizer, moisturizer, and skin pH did not correlate with the incidence of hand eczema. Conclusion: Frequency of handwashing and the duration of using latex gloves correlated with the incidence of hand eczema, meanwhile frequency of using hand sanitizer, using moisturizer, and skin pH didn't correlate with the incidence of hand eczema.
STUDI RETROSPEKTIF HEMANGIOMA INFANTIL DI RUMAH SAKIT PUSAT RUJUKAN DI SURAKARTA JAWA TENGAH Widhiati, Suci; Rahma, Alfina; Ellistasari, Endra Yustin; Nareswari, Adniana
Media Dermato-Venereologica Indonesiana Vol 52 No 2 (2025): Media Dermato Venereologica Indonesiana
Publisher : Perhimpunan Dokter Spesialis Kulit dan Kelamin Indonesia (PERDOSKI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33820/mdvi.v52i2.398

Abstract

   Pendahuluan: Hemangioma infantil (HI) merupakan tumor jinak vaskular yang muncul dalam beberapa minggu pertama kehidupan. Prevalensi HI secara global sekitar 4,5%. Umumnya HI tidak memerlukan terapi dan mengalami regresi spontan, namun 10-15% akan mengakibatkan komplikasi seperti obstruksi, ulserasi atau cacat. Tujuan penelitian ini untuk mengetahui karakteristik pasien baru HI di instalasi rawat jalan RSUD Dr. Moewardi Surakarta periode 1 Januari 2019 - 31 Desember 2021. Metode: Metode penelitian ini merupakan retrospektif dengan desain potong lintang, Data diambil dari rekam medis pasien hemangioma yang datang ke Instalasi Rawat Jalan RSUD Dr. Moewardi Surakarta periode 1 Januari 2019 - 31 Desember 2021. Hasil: Terdapat 135 pasien yang didiagnosis HI dengan kisaran usia 7 hari hingga 13 tahun. Kelompok usia terbanyak adalah 0-1 tahun sebanyak 69 pasien (51,11%), perempuan sebanyak 88 pasien (65,19%). Awitan terbanyak usia < 2 bulan yaitu 94 pasien (69,63%). Ujud kelainan kulit terbanyak berupa nodul sebanyak 101 pasien (74,81%), soliter pada 124 pasien (91,85%). Predileksi pada kepala dan leher sebanyak 76 pasien (56,29%). Pasien lahir aterm sebanyak 111 pasien (82,22%), berat badan lahir cukup 123 pasien (91,11%). Riwayat persalinan pervaginam 100 pasien (74,07%). Modalitas terapi terbanyak propranolol pada 37 pasien (27,42%). Kesimpulan: Gambaran HI di RSUD Dr. Moewardi Surakarta berdasarkan awitan, predileksi, jumlah lesi, manifestasi klinis dan terapi sesuai dengan deskripsi teori, namun faktor risiko yang diteliti tidak sejalan dengan teori. 
Co-Authors -, Frieda Dita Eka Novriana Eko Irawanto, Muhammad Ellistasari, Endra Yustin Irawanto, Muhammad Eko Kariosentono, Harijono Kusumawardani, Arie Nareswari, Adniana Novi Diana, Eka Devinta Nugraha, Wibisono Rosmarwati, Ervina Tri Irfanti, Rakhma Triasari Oktavriana Widhiati, Suci